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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | 查看详情显示文摘 | MO Y R BAO P GAO J L | | 0，，： | 1 |
| 3 | A nonstationary signal simulation model for continuous wave and pulsed doppler ultrasound显示文摘 | MO L Y L (30BBOLD R S C | 1989 | IEEE Trans Ultrason Ferroelec Freq Contr1989，36，： | 1 |
| 4 | An inactivated enterovirus 71 vaccine in healthy children显示文摘 | Li R Liu L Mo Z et ai | 2014 | N EnglJ Med2014，370，9： | 1 |
| 5 | An inactivated enterovirus 71vaccine in healthy children显示文摘 | Li R Liu L Mo Z | 2014 | N Engl J Med2014，370，9： | 1 |
| 6 | Interplays of Gli2 and Gli3 and their requirement in mediating Shh - dependent sclerotome in- duction显示文摘 | Buttitta L Mo R Hui CC | 2003 | Development2003，130，： | 1 |
| 7 | Analysis of functional properties of Lactobacillus acidophilus 显示文摘 | Zhao R X Sun J L Mo H Z | 2007 | World J Microbiol Biotechol2007，23，2： | 1 |
| 8 | Biology of cutaneous squamous cell carcinoma 显示文摘 | KWA R E CAMPANA K Mo~ R L | 1992 | Journal of the American Academy of Dermatology1992，26，1： | 1 |
| 9 | New methods of creating MBD process model:on the basis of machining knowledge显示文摘 | WAN N MO R LIU L L | 2014 | Computers in Industry2014，65，4： | 1 |
| 10 | Diagnostic and therapentic interventions in post laparoscopic cholecystectomy biliary complications显示文摘 | YAU M P TSAI C C MO L R | 1991 | Hepato Gastroenterol1991，40，： | 1 |
| 11 | Palliative percutane- ous transhepatic gallbladder drainage of gallbladder empyema before laparoscopic cholecystectomy 显示文摘 | TSENG L J TSAI C C MO L R | 2000 | Hepatogastroenterology2000，34，47： | 1 |
| 12 | F l u i d –solid interaction simulation of flow and stress pattern inthoracoabdominal aneurysms:a patient-specific study显示文摘 | B o r g h i A Wo o d NB Mo h i a d d i n RH e t a l | 2008 | JFluids Struct2008，24，2： | 1 |
| 13 | Analysis of functional properties of Lactobacillus acidophilus 显示文摘 | Zhao R X Sun J L Mo H Z | 2007 | World Journal of Microbiology and Biotechnology2007，23，2： | 1 |
| 14 | Finding the most vital arcs in a network显示文摘 | Ball Mo Golden B L Vohra R V | 1989 | Operation Research Letters1989，8，2： | 1 |
| 15 | H ydrothermal syntheses and structural diversity of cobalt complexes with 2, 2'-Bibenzimidazole ligand by temperature tuning strategy 显示文摘 | MO H J ZHONG Y R CAO M L | 2009 | Inorg Chem2009，9，1： | 1 |
| 16 | The NCEP/NCAR 40-yeax reanalysis project 显示文摘 | E Kalnay M Kanamitsu R Kistler WCollins D Deaven L Gandin M Iredell S Saha G White J Woollen Y Zhu M Chelliah W Ebisuzaki W Higgins J Janowiak KC Mo C Ropelewski J Wang A Leetmaa R Reynolds R Jenne D Joseph | 1996 | Bulletin of the American Meteorological Society (S0003-0007)1996，77，3： | 1 |
| 17 | Preoperative endoscopic sphinctemtomy in the treatment of patients with cholecystocholedoe holithiasis 显示文摘 | Mo L R Chang K K Wang C H | 2002 | J Hepatobiliary Surg2002，9，2： | 1 |
| 18 | An inactivated enteruvirus 71 vaccine in healthy children 显示文摘 | Li R Liu L Mo Z et ol | 2014 | N Engl J Med2014，370，9： | 1 |
| 19 | capsule endoscopy for gastrointestinal bleeding with an obscure etiology 显示文摘 | Chao C C Ng Jao Y T Mo L R | 2005 | J Formos Med Assoc2005，104，9： | 1 |
| 20 | Rapid diagnosis of choledocholithiasis using biochemical tests in patients undergoing laparoscopic cholecystectomy 显示文摘 | Wang C H Mo L R Lin R C | 2001 | Hepatogas Troenterology2001，48，39： | 1 |
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