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| 1 | CoolClot,a novel hemostatic agent for controlling life-threatening arterial bleeding显示文摘BACKGROUND:Uncontrolled bleeding is the first leading cause of preventable death in the battlefield and the 2nd cause of mortality in civil accidents.Incompressible hemorrhage control is among the interventions that drastically increase the survival rate in wound individuals.We have previously shown that a certain mixture of bentonite and zeolite minerals can significantly decrease the bleeding in rats.METHODS:In this study,nine healthy hybrid dogs were selected and after induction of anesthesia with ether,either arterial puncture by a needle or arteriotomy was performed on both groin regions of the dogs.For control arteries(either the right or left femoral artery),only pressure by sterilized gauze was performed,while for the femoral arteries of the opposite side,our invented hemostatic agent,namely CoolClot,was topically used before applying the pressure.In the second stage of the study,to assess the coagulation time,blood samples were collected from 10 volunteer students.RESULTS:CoolClot significantly decreased the bleeding time in animals whose femoral arteries were cut or punctured.In the human phase of the study,the mean coagulation time in control blood samples was 253.4+44.1 seconds,whereas it was 149.5+50.0,162.3±74.6 and 143.4±114.6seconds,respectively in blood samples treated with bentonite,zeolite and CoolClot(P<0.05).CONCLUSIONS:As controlling bleeding after a life-threatening arterial damage is critical for increasing the chance of survival,the results obtained in this study indicate the significant efficacy of CoolClot in shortening the bleeding time.Our experiments also indicate that CoolClot can significantly reduce the clotting time in human blood samples. | SMJ Mortazavi A Tavasoli M Atefi N Tanide N Radpey P Roshan-shomal H Moradi S Taeb | 2013 | World Journal of Emergency Medicine2013，4，2： | 2 |
| 2 | The effect of different molar ratios of ZnO on characterization and photocatalytic activity of TiO2/ZnO nanocomposites显示文摘 | MORADI S ABEROOMAND-AZAR P RAEIS-FARSHID S | 2012 | Journal of Saudi Chemical Society2012，8，2： | 1 |
| 3 | Modular construc- tion of multifunctional bioresponsive cell-targeted nanoparti- cles for gene delivery 显示文摘 | Saeed A O Magnusson J P Moradi E | 2011 | Bioconjugate Chem2011，22，： | 1 |
| 4 | Factors associatedwith death or intensive care unit admission due to pandemic2009 influenza A (H1N1) infection 显示文摘 | Tabarsi P Moradi A Marjani M | 2011 | Ann Thorac Med2011，6，2： | 1 |
| 5 | Velocity based artificial bee colony algorithm for high dimensional continuous optimization problems 显示文摘 | Imanian N Shiri M E Moradi P | 2014 | Engineering Applications of Artificial Intelligence2014，，36： | 1 |
| 6 | Factors associated with death or intensive care unit admission due to pandemic 2009 influenza A ( H1 N1 ) infection 显示文摘 | TABARSI P MORADI A MARJANI M | 2011 | Ann Thorac Med2011，6，2： | 1 |
| 7 | Factors associated with death or intensive care unit admission due to pandemic 2009 influenza A(H1N1) infection显示文摘 | Tabarsi P Moradi A Marjani M | 2011 | Ann Thorac Med2011，6，2： | 1 |
| 8 | Hydrolysis and precipitation of poly- acrylamide in hard brines at elevated temperatures 显示文摘 | Moradi A A Doe P H | 2007 | Soc Pet Eng Reservoir Eng2007，，2： | 1 |
| 9 | Standardised second-line treatment of multidrug-resistant tuberculosis during pregnancy显示文摘 | Tabarsi P Moradi A Baghaei P | | 0，，04： | 1 |
| 10 | An unsupervised feature selection algorithm based on ant colony optimization显示文摘 | TABAKHI S MORADI P AKHLAGHIAN F | 2014 | Engineering Applications of Artificial Intelligence2014，32，： | 1 |
| 11 | Responses of photosynthesis, chloro- phyll fluorescence and ROS-scavenging systems to salt stress during seedling and reproductive stages in rice 显示文摘 | Moradi P Ismail A M | 2007 | Annals of Botany2007，99，6： | 1 |
| 12 | Response to Pacing at Sites of Isolated Diastolic Potentials During Ventricular Tachycardia in Patients With Previous Myocardial Infarction显示文摘 | Frank Bogun Marwan Bahu Bradley P Knight Raul Weiss Rajiva Goyal Emile Daoud K.Ching Man S.Adam Strickberger Fred Morady | 1997 | Journal of the American College of Cardiology1997，，： | 1 |
| 13 | Augmenting detection of prostate cancer in transrectal ultrasound images using SVM and RF time series 显示文摘 | Moradi M Mousavi P Boag AH | 2009 | IEEE Trans Biomed Eng2009，56，9： | 1 |
| 14 | A Novel ap- proach in R peak detection using hybrid complex wave- let (HCW) 显示文摘 | Fard P J M Moradi M H Tajvidi M R | 2008 | International Journal of Cardiology2008，124，2： | 1 |
| 15 | Discrete Fourier analysis of ultrasound RF time series for detection of prostate cancer 显示文摘 | Moradi M Mousavi P Siemens DR | 2007 | Conf Proc IEEE Eng Med Biol Soc2007，2007，29： | 1 |
| 16 | Standardised secondline treatment of multidrug-resistant tuberculosis during pregnancy显示文摘 | Tabarsi P Moradi A Baghaei P | | 0，，04： | 1 |
| 17 | Reconstruction of pharyngo- laryngectomy defects using the jejunal free flap: a 10-year experience from a single reconstructive center显示文摘 | Moradi P Glass GE Atherton DD | 2010 | Plast Reconstr Surg2010，126，6： | 1 |
| 18 | Effect of chronic kidney disease on the expression of thiamin and folic acid transporters显示文摘 | Bukhari FJ Moradi H Gollapudi P | | 0，，7： | 1 |
| 19 | Tissue characterization using fractal dimension of high frequency ultrasound RF time series 显示文摘 | Moradi M Mousavi P Abolmaesumi P | 2007 | Med Image Comput Comput Assist Interv2007，10，2： | 1 |
| 20 | A human health risk assessment of soil and crops contaminated by heavy metals in industrialregions,central Iran显示文摘 | MORADI A HONARJOO N NAJAFI P | 2016 | Human and ecological risk assessment:An international journal2016，22，1： | 1 |
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