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16篇 您的检索式:作者名="Mshelia"
    题名 作者 年代 出处 被引量
1Oestrus detection in the Nigerian Mongrel bitch:application of vaginal cytology显示文摘Mshelia G D Amin J D Chaudhari S U R 2001Pakistan Veterinary Journal2001,21,1:1
2The use of plasma lipid and lipoprotein ratios in interpreting the hyperlipidaemia of pregnancy显示文摘Mshelia DS Kullima A Gali RM 2010J Obstet Gynaecol2010,30,8:1
3The Production of Oxygen Gas显示文摘Onuchukwu IA I Mshelia P B 1985J Chem Edu1985,62,9:1
4The prodution of oxygex gas显示文摘Onuchukwu A I Mshelia P B 1985J Chem Educ1985,62,9:1
5Prevalence and pattern of brown adipose tissue distribution of 18 F-FDG in patients undergoing PET-CT in a subtropical climatic zone显示文摘Perkins AC Mshelia DS Symouds ME 2013Nucl Med Commun2013,34,2:1
6Antibacterial Susceptibility of Klebsiella pneumoniae Isolates from Respiratory Tract Infections to Honey and Lemon显示文摘G. O. Adeshina B. M. Mshelia J. A. Onaolapo 2014Annual Research & Review in Biology2014,,4:1
7The prevalence of bovine venereal campylobacteriosis in cattle herds in the Lake Chad basin of Nigeria显示文摘Mshelia GD Amin JD Egwu GO 0,,07:1
8The immune status of the bovine uterus during the peripartum period显示文摘Singh J Murray R D Mshelia G 0,,:1
9Effect of increased patient - physician contact time and health edu- cation in achieving diabetes mellitus management objectives in a resource - poor environment 显示文摘Mshelia DS Akinosun OM Abbiyesuku FM 2007Singapore Med J2007,48,1:1
10Beta-lactamase Escherichia coli and Staphylococcus aureus isolated from chickens in Nigeria显示文摘MAMZA S A EGWU G O MSHELIA G D 2010Veterinaria Italian2010,46,2:1
11The immune status of the bovine uterus during the peripartum period 显示文摘Singh J Murray R Mshelia G 2008Vet J2008,175,3:1
12The inunune status of the bovine uterus during the peripartum period 显示文摘SINGH J MURRAY R D MSHELIA G 2008Vet J2008,175,:1
13Prevalence and pattern of brown adipose tissue distribution of 18lF-FDG in patients undergoing PET CT in a subtropical climatic zone显示文摘Perkins AC Mshelia DS Symonds ME 0,,:1
14Effect of increased patient-physician contact time and health education in achieving diabetes mellitus management objectives in a resource-poor environment显示文摘Mshelia DS Akinosun OM Abbiyesuku FM 2007Singapore Med J2007,48,1:1
15Point of care testing:a delight or a dilemma in the developing world?:an overview显示文摘Mshelia DS Buba AA 0,,02:1
16Therapeutic efficacy of voltage‑gated sodium channel inhibitors in epilepsy显示文摘Epilepsy is a neurological disease characterized by excessive and abnormal hyper-synchrony of electrical discharges of the brain and a predisposition to generate epileptic seizures resulting in a broad spectrum of neurobiological insults,imposing psychological,cognitive,social and also economic burdens to the sufferer.Voltage-gated sodium channels(VGSCs)are essential for the generation and propagation of action potentials throughout the central nervous system.Dysfunction of these channels has been implicated in the pathogenesis of epilepsy.VGSC inhibitors have been demonstrated to act as anticonvulsants to suppress the abnormal neuronal firing underlying epileptic seizures,and are used for the management and treatment of both genetic-idiopathic and acquired epilepsies.We discuss the forms of idiopathic and acquired epilepsies caused by VGSC mutations and the therapeutic efficacy of VGSC blockers in idiopathic,acquired and pharmacoresistant forms of epilepsy in this review.We conclude that there is a need for better alternative therapies that can be used alone or in combination with VGSC inhibitors in the management of epilepsies.The current anti-seizure medications(ASMs)especially for pharmacoresistant epilepsies and some other types of epilepsy have not yielded expected therapeutic efficacy partly because they do not show subtype-selectivity in blocking sodium channels while also bringing side effects.Therefore,there is a need to develop novel drug cocktails with enhanced selectivity for specific VGSC isoforms,to achieve better treatment of pharmacoresistant epilepsies and other types of epileptic seizures.John Agbo Zainab G.Ibrahim Shehu Y.Magaji Yahkub Babatunde Mutalub Philemon Paul Mshelia Daniel H.Mhyha 2023Acta Epileptologica2023,6,2:0
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