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| 1 | Cloning and sequence characteristics of the genomic gene of a rice metallothionein显示文摘Northern blot analysis showed that a metallothionein gene, ricMT is expressed strongly in the stem of rice with an expression level that could be more than 100-fold stronger than in leaf blades. The results suggest that the 5’ upstream region flanking the coding sequence of the ricMT may contain a fairly strong promoter To elucidatr its regulation and promoter structure, the genomic clones of ricMT were screened out from a rice genomic library and a fragment of about 4084 bp was sequenced. The fragment included a 5’ upstream region of ca. 2970 bp, a transcription region of ca. 690 bp and a 3’ downstream region of ca. 420 bp. Computer analysis of the sequence homology showed that the 5’ upstream region included a putative TATA box, a putative CAAT box, and a typical metal-responsive element TGCGCGCG. The results will promote further understanding of the mechanisms of gene regulation and metal response of plant metallothionein proteins. | YU Lihua, LIU Jinyuan, Masaaki Umeda, Hirofumi Uchimiya & ZHAO Nanming Department of Biological Sciences and Biotechnology, State Key Laboratory of Biomembrane and Membrane Biotechnology, Beijing 100084, China Institute of Molecular and Cellular Bioscie | 2000 | Chinese Science Bulletin2000，45，2： | 4 |
| 2 | The mitochondrial function was impaired in APP knockout mouse embryo fibroblast cells显示文摘The amyloid precursor protein (APP) is recognized as the source of Aβ, which plays an important role in Alzheimer’s disease. However, the biological function of APP is obscure. Previous studies showed that mitochondria could be a target of APP. In this work, APP knockout mouse embryo fibroblast (MEF) cells were used to test if APP plays any role in maintaining the mitochondrial function. As the result, APP knockout MEF cells (APP-/- cells) showed the abnormal mitochondrial function, including slower cell proliferation, lower mitochondrial membrane potential, lower intracellular ROS, higher mitochondrial membrane fluidity and lower cytochrome c oxidase activity than their wild-type counterparts. However, no change was found in the amount of mitochondria in MEF APP-/-cells. | SHENG BaiYang NIU Ying ZHOU Hui ZHOU Hui YAN JiaXin ZHAO NanMing ZHANG XiuFang GONG YanDao | 2009 | Chinese Science Bulletin2009，54，10： | 2 |
| 3 | Progress in artificial control system for gene expression显示文摘Along with the increasingly wide application of transgenic techniques, new stricter criteria have been raised for controlling the expression of exogenous genes. For these demands, a series of artificial control systems for gene expression have been developed and testified in recent years, which can control exogenous genes expression in exact time and certain level by administration of a specific drug or hormone. The successful construction of these systems offers a practicable method to control precise expression of exogenous gene in organisms, and raises the feasibility of wide application of gene therapy. | ZHANG Yong ZHAO Nanming LIU Qiang | 2000 | Chinese Science Bulletin2000，45，10： | 2 |
| 4 | Short term hydrothermal coordination using multi-pass dynamic programming显示文摘 | Yang Jin-Shyr Chen Nanming | 1989 | IEEE Transactions on Power Systems1989，4，3： | 1 |
| 5 | Effects of ELF electric field on proliferation of mouse osteoblastic cells 显示文摘 | Qing T Gung C Nanming Z | 1998 | Bioelectrochem Bioenerg1998，47，： | 1 |
| 6 | Modes of operation in parallel-connected 12-pulse uncontrolled bridge rectifiers without an interphase transformer显示文摘 | Yii-Shen Tzeng Nanming Chen Ruay-Nan Wu | | 0，，03： | 1 |
| 7 | Short term hydrothermal coordination using multi-pass dynamic programming显示文摘 | Yang Jin-Skyr Chen Nanming | 1989 | IEEE Transactions on Power Systems1989，4，3： | 1 |
| 8 | Studies on nerve cell affinity of biodegradable modified chitosan films显示文摘 | Mingyu Cheng Wenling Cao Yuan Gao Yandao Gong Nanming Zhao Xiufang Zhang | 2003 | Journal of Biomaterials Science Polymer Edition2003，，10： | 1 |
| 9 | Expression of vascular endothelial growth factor and vascular endothelial growth factor recep- tors 1 and 2 in invasive breast carcinoma: prognostic significance and relationship with markers for aggressiveness 显示文摘 | Dhakal HP Nanme B Synnestvedt M | 2012 | Histopathology2012，61，： | 1 |
| 10 | Direct search method for solving economic dispatch problem considering transmission capacity constraints 显示文摘 | Chun-Lung Chen Nanming Chen | 2001 | IEEE Transactions on Power Systems2001，16，4： | 1 |
| 11 | Properties and biocompatibility of chitosan films modified by blending with PEG显示文摘 | Zhang Miao Li Xunhu Gong Yandao Zhao Nanming Zhang Xiufang | | 0，，： | 1 |
| 12 | Determination of optimal contract capacities and optimal sizes of battery energy storage systems for time-of-use rates industrial customers显示文摘 | Lee Tsung-Ying Chen Nanming | | 0，，03： | 1 |
| 13 | Slip-Control Strategy of Dual Independent Electric Drive Tracked Vehicle显示文摘In order to improve the brake performance of a dual independent electric drive tracked vehicle,a dynamic model for braking situation was established.Then,a sliding model controller(SMC)with an auxiliary system was designed to control the slip and its effectiveness was proved.A hardware-in-loop simulation through MATLAB/XPC was compared with the normal SMC and normal integral sliding mode controller(ISMC),the results show that SMC with the auxiliary system has a better performance:a smaller overshoot and steady state error.The disturbance is suppressed effectively.In the initial speed of 65.km/h,the brake distance was shortened by 3.4%and 6.8%compared with the other two methods,respectively.Finally,initial speeds of 30-36.km/h tests was carried out on a flat soil road.Compared with a no-control brake,the displacement was shortened by 1.8.m.It demonstrates the effectiveness of the slip-control strategy.In the same situation,the error between the simulation and test is 18.1%,which validates the accuracy of models. | Shuyang Zhang Yunan Zhang Keyan Ning Nanming Yan Qingfeng Fang | 2019 | Journal of Beijing Institute of Technology2019，28，4： | 1 |
| 14 | Electronic structure of disordered Au-Pd alloys studied by electron spectroscopies显示文摘 | Nanm T Jung R | 1998 | Phys Rev B1998，58，15： | 1 |
| 15 | circulating and disseminated tumor cells显示文摘 | Braun S Nanme B | 2005 | J Clin Oncol2005，23，8： | 1 |
| 16 | Studies on nerve cell affinity of biodegradable modified chitosan films显示文摘 | Mingyu Cheng Wenling Cao Yuan Gao Yandao Gong Nanming Zhao Xiufang Zhang | 2003 | Journal of Biomaterials Science Polymer Edition2003，，10： | 1 |
| 17 | Short Term Hydrothermal Coordination Using Multi-pass Dynamic Programming显示文摘 | Jin-Shyr Yang Nanming Chen | 1989 | IEEE Transactions on Power Systems1989，4，3： | 1 |
| 18 | Endogenously generated amyloid β increases membrane fluidity in neural 2a cells显示文摘The effect of endogenously generated amyloid β on membrane fluidity was investigated in Neural 2a cells stably expressing Swedish mutant amyloid precursor protein (APPswe). Membrane fluidity was studied by fluorescence polarizability using 1,6-Diphenyl-1,3,5-Hexatriene (DPH) as the fluorescence probe. It was found that the membrane fluidity in APPswe cells was significantly higher than that in its wild type counterparts. Alleviating the effect of amyloid β either by γ secretase activity inhibition or by amyloid antibody treatment decreased membrane fluidity, which indicated an important role of amyloid β in increasing membrane fluidity. Treatment using amyloid β channel blocker, tromethamine and NA4 suggested that channel formed by amyloid β on the cell membrane is a way through which amyloid β takes its membrane fluidizing effect. | NIU Ying SHENG BaiYang SONG Bo LIU LingLing ZHANG XiuFang ZHAO NanMing GONG YanDao | 2009 | Chinese Science Bulletin2009，54，3： | 1 |
| 19 | Study on physical properties and nerve cell affinity of composite films from chitosan and gelatin solutions显示文摘 | Mingyu Cheng Jinguang Deng Fei Yang Yandao Gong Nanming Zhao Xiufang Zhang | 2003 | Biomaterials2003，，17： | 1 |
| 20 | Determination of optimal contract capacities and optimal sizes of battery energy storage systems for time-of-use rates industrial customers 显示文摘 | Lee Tsung-Ying Chen Nanming | 1995 | IEEE Trans on Energy Conversion1995，0，3： | 1 |
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