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| 1 | Antihyperglycemic activity,antihyperlipedemic activity,haematological effects and histopathological analysis of Sapindus mukorossi Gaerten fruits in streptozotocin induced diabetic rats显示文摘Objective:To investigate the antihyperglycemic and antihyperlipidemie properties of hydroalcoholic extract of fruits of Sapindus mukorossi Caerlen and its beneficial effect on haeniatological parameters with histopathological analysis in streptpzotocin induced diabetic rats.Methods:Sapindus mukorossi fruits extract(250 and 500 mg/kg body weight) and standard drug glybenclamide(0.5 mg/kg body weight) were administered to diabetic rats.Effect of extract on hyperglycemia,hyperlipidemia and hematological parameters was studied in diabetic rats.Histopathological changes in diabetic rat pancreas were also observed after extract and glybenclamide treatment.Results:Daily oral administration of Sapindus mukorossi fruits extract(250 and 500 mg/kg body weight) and glybenclamide for 20 days showed beneficial effects on blood glucose level(P<0.01) and lipid level.The extract has a favorable effect on the histopathological changes of the pancreas in streptozotocin induced diabetes.Conclusions: These findings reveal that the hydroalcoholic extract of Sapindus mukorossi fruits extract possesses antihyperglycemic and antihyperlipidemie properties.In addition.the extract can prevent various complications of diabetes and improve some haeniatological parameters. | Neeraj Verma G Amresh P K Sahu Neelam Mishra Anil P Singh Ch V Rao | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，7： | 14 |
| 2 | Evaluation of anti-apoptotic activity of different dietary antioxidants in renal cell carcinoma against hydrogen peroxide显示文摘Objective:To evaluate the anti-apoptotic and radical scavenging activities of dietary phenolics, namely ascorbic acid,a-tocopherol acetate,citric acid,salicylic acid,and estimate H_2O_2induced apoptosis in renal cell carcinoma cells.Methods:The intracellular antioxidant potency of antioxidants was investigated.H_2O-2-induced apoptosis in RCC-26 was assayed with the following parameters:cell viability(%apoptosis),nucleosomal damage and DNA fragmentation, bcl-2 levels and flow cytometery analysis(ROS production evaluation).Results:Ine anticancer properties of antioxidants such as ascorbic acid,a- tocopherol acetate,citric acid,salicylic acid with perdurable responses were investigated.It was observed that these antioxidants had protective effect(anti-apoptotic activity) against hydrogen peroxide(H_2O_2) in renal cell carcinoma(RCC-26) cell line.Conclusions:This study reveals and proves the anticancer properties.However,in cancer cell lines anti-apoptotic activity can indirectly reflect the cancer promoter activity through radicals scavenging,and significantly protect nucleus and bcl-2. | Garg Neeraj K Mangal Sharad Sahu Tejram Mehta Abhinav Vyas Suresh P Tyagi Rajeev K | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，1： | 4 |
| 3 | Anti-arthritis activity of roots of Hemidesmus indicus R.Br.(Anantmul)in rats显示文摘Objective:To investigate the protective effects of hydroalcoholic and its fractions from roots of Hemidesmus indicus on arthritis in in vitro models of rodents.Methods:Preliminary phytochemical analysis and thin-layer chromoatography were performed to analyze constituents of hydroalcoholic extract and its three fraction namely ethyl acetate fraction,chloroform fraction and residual fraction of mot of Hemidesmus indicus.Arthritis rats models were established by Complete Freund’s Adjuvant.The parameters including paw edema,body weight,arthritic index,erythrocyte sedimentation rate,serum rheumatoid factor,serum C-reactive protein,serum nitrite level,and histopathology of synovial joints were observed.Methotrexate was taken as positive control.Results:Rats treated with hydroalcoholic extract(450 mg/kg,p.o.),ethyl acetate (75 mg/kg,p.o.),chloroform(60 mg/kg,p.o) and residual fractions(270 mg/kg,p.o.),showed significant decrease in physical and biochemical parameters compared with arthritic model rats. Hydroalcoholic extract and its ethyl acetate fraction of Hemidesmus indicus showed significantly higher anti-arthritic activity than chloroform and residual fraction.Histopathological analysis demonstrated that both of hydroalcoholic extract and its ethyl acetate fraction had comparable anti-arthritic activity with methotrexates.Conclusions:The present study suggests that Hemidesmus indicus has protective activity against arthritis and the activity might be attributed to presence of terpenoid in hydroalcoholic extract,as well as in ethyl acetate fraction. | Alka Mehta Neeraj K Sethiya Chetan Mehta GB Shah | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，2： | 4 |
| 4 | Biosorptionof Chromium (Vl) from Aqueous Solutions by Green Algae Spirogyra Species显示文摘 | Gopta V K Shfivastava A K Neeraj Jain | 2001 | Water Research2001，35，17： | 1 |
| 5 | White light upconversion emissions from Tm^3+-Ho^3+-Yb^3+ codoped tellurite and germinate glasses on exeitation with 798 nm radiation 显示文摘 | Neeraj K G Rai D K Rai S B | 2008 | J Appl Phys2008，104，11： | 1 |
| 6 | Probabilistic trust aware data replicaplacement strategy for online video streaming applications delaytolerant networks 显示文摘 | Neeraj K Jongsung K | 2013 | Mathematical and Computer Modeling2013，58，12： | 1 |
| 7 | Novel red phosphors for solid-state lighting: the system NaM (WO4)2-x (MoO4)x : Eu^3+(M=Gd, Y, Bi) 显示文摘 | Neeraj S Kijima N Cheetham A K | 2004 | Chemical Physics Letters2004，387，： | 1 |
| 8 | Single nucleotide mutation in the barley acetohydroxy acid synthase (AHAS) gene confers resistance to imidazoline herbi- cides 显示文摘 | Lee I-I Sachin R Neeraj K | 2011 | Proc Natl Acda Sci USA2011，108，： | 1 |
| 9 | Structure and magnetic properties of a three-dimensional framework manganese (II) phosphate, 显示文摘 | Neeraj S Maria L Noy Anthony K Cheetham | 2002 | Solid State Sciences2002，4，： | 1 |
| 10 | Steady-state and dynamic modeling of gas-phase polypropylene processed using stirred-bed reactors 显示文摘 | Neeraj P Hare K Bruce Lucas | 2004 | Ind Eng Chem Res2004，43，： | 1 |
| 11 | 查看详情显示文摘 | Neeraj S Kijima N Cheetham A K | | 0，，1： | 1 |
| 12 | Novel red phosphors for solid-state lighting: the system NaM(WO4 ) z- x (MOO4) x Eu3+ (M= Gd, Y, Bi) 显示文摘 | Neeraj S Kijima N CheethamA K | 2004 | Chem Phys Lett2004，387，： | 1 |
| 13 | Reliability properties of reversed residual lifetime显示文摘 | Asok K Nanda Harshinder Singh Neeraj Misra | 2003 | Communications in Statistics Theory and Methods2003，32，10： | 1 |
| 14 | Novel red phosphors for solid state lighting; the system Bi_xLn_(1-x)VO_4; Eu~(3+)/Sm~(3+) (Ln = Y, Gd)显示文摘 | Neeraj S Kijima N Cheetham A K | | 0，，01： | 1 |
| 15 | Novel red phosphors for solid state lighting; the system BixLnl_x V04; Eu3+/Sm3+ (Ln= Y, Gd) 显示文摘 | Neeraj S Kijima N Cheetham A K | 2004 | Solid State Communications2004，131，： | 1 |
| 16 | Trend analysis of antimicrobial consumption and development of resistance in non-fermenters in a tertiary care hospital in Delhi,India显示文摘 | Neeraj G Chand W Jaswinder K Ob | | 0，，07： | 1 |
| 17 | Importance of patient-centered care in enhancing patient well-being:a cancer survivor's perspective显示文摘 | Neeraj K A | 2009 | Qual Life Res2009，18，： | 1 |
| 18 | Trend analysis of antimicrobial consumption and development of resistance in non-fermenters in a tertiary care hospital in Delhi, India 显示文摘 | Neeraj G Chand W Jaswinder K O b | 2011 | J Antimicrob Agents2011，66，7： | 1 |
| 19 | Novel red phosphors for solid-state lighting: the system NaM (WO4)2-x( MoO4 )x: Eu^3+ ( M = Gd, Y, Bi ) 显示文摘 | Neeraj S Kijima N Cheetham A K | 2004 | Chemi Phys Lett2004，387，123： | 1 |
| 20 | Grain boundary effects on the electrical and magnetic properties of Pr2/3Ba1/3MnO3 and La2/3Ca1/3MnO3 manganites 显示文摘 | NEERAJ P VIKRAM S PANDVA D K AGARAWAL S K | 2007 | Mater Lett2007，61，： | 1 |
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