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您的检索式：作者名="Mehta Abhinav"
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| 1 | Evaluation of anti-apoptotic activity of different dietary antioxidants in renal cell carcinoma against hydrogen peroxide显示文摘Objective:To evaluate the anti-apoptotic and radical scavenging activities of dietary phenolics, namely ascorbic acid,a-tocopherol acetate,citric acid,salicylic acid,and estimate H_2O_2induced apoptosis in renal cell carcinoma cells.Methods:The intracellular antioxidant potency of antioxidants was investigated.H_2O-2-induced apoptosis in RCC-26 was assayed with the following parameters:cell viability(%apoptosis),nucleosomal damage and DNA fragmentation, bcl-2 levels and flow cytometery analysis(ROS production evaluation).Results:Ine anticancer properties of antioxidants such as ascorbic acid,a- tocopherol acetate,citric acid,salicylic acid with perdurable responses were investigated.It was observed that these antioxidants had protective effect(anti-apoptotic activity) against hydrogen peroxide(H_2O_2) in renal cell carcinoma(RCC-26) cell line.Conclusions:This study reveals and proves the anticancer properties.However,in cancer cell lines anti-apoptotic activity can indirectly reflect the cancer promoter activity through radicals scavenging,and significantly protect nucleus and bcl-2. | Garg Neeraj K Mangal Sharad Sahu Tejram Mehta Abhinav Vyas Suresh P Tyagi Rajeev K | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，1： | 4 |
| 2 | Glucose levels compared with diabetes history in the risk assessment of patients with acute myocardial infarction显示文摘 | Abhinav Goyal Shamir R. Mehta Hertzel C. Gerstein Rafael Díaz Rizwan Afzal Denis Xavier Jun Zhu Prem Pais Liu Lisheng Khawar A. Kazmi Mohammad Zubaid Leopoldo S. Piegas Petr Widimsky Andrzej Budaj Alvaro Avezum Salim Yusuf | 2009 | American Heart Journal2009，，4： | 1 |
| 3 | The Versatility and Diagnostic Potential of VOC Profiling for Noninfectious Diseases显示文摘variety of volatile organic compounds(VOCs)are produced and emitted by the human body every day.The identity and concentration of these VOCs reflect an individual’s metabolic condition.Information regarding the production and origin of VOCs,however,has yet to be congruent among the scientific community.This review article focuses on the recent investigations of the source and detection of biological VOCs as a potential for noninvasive discrimination between healthy and diseased individuals.Analyzing the changes in the components of VOC profiles could provide information regarding the molecular mechanisms behind disease as well as presenting new approaches for personalized screening and diagnosis.VOC research has prioritized the study of cancer,resulting in many research articles and reviews being written on the topic.This review summarizes the information gained about VOC cancer studies over the past 10 years and looks at how this knowledge correlates with and can be expanded to new and upcoming fields of VOC research,including neurodegenerative and other noninfectious diseases.Recent advances in analytical techniques have allowed for the analysis of VOCs measured in breath,urine,blood,feces,and skin.New diagnostic approaches founded on sensor-based techniques allow for cheaper and quicker results,and we compare their diagnostic dependability with gas chromatography-and mass spectrometry-based techniques.The future of VOC analysis as a clinical practice and the challenges associated with this transition are also discussed and future research priorities are summarized. | Micah Oxner Allyson Trang Jhalak Mehta Christopher Forsyth Barbara Swanson Ali Keshavarzian Abhinav Bhushan | 2023 | Biomedical Engineering Frontiers2023，4，1： | 0 |
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