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| 1 | Infectious burden and atherosclerosis: A clinical issue显示文摘Atherosclerotic cardiovascular diseases, chronic inflam-matory diseases of multifactorial etiology, are the lead-ing cause of death worldwide. In the last decade, more infectious agents, labeled as 'infectious burden', rather than any single pathogen, have been showed to con-tribute to the development of atherosclerosis through different mechanisms. Some microorganisms, such as Chlamydia pneumoniae(C. pneumoniae), human cytomegalovirus, etc. may act directly on the arterial wall contributing to endothelial dysfunction, foam cell formation, smooth muscle cell proliferation, platelet ag-gregation as well as cytokine, reactive oxygen specie, growth factor, and cellular adhesion molecule produc-tion. Others, such as Helicobacter pylori(H. pylori), in-fluenza virus, etc. may induce a systemic inflammation which in turn may damage the vascular wall(e.g., by cytokines and proteases). Moreover, another indirect mechanism by which some infectious agents(such as H. pylori, C. pneumoniae, periodontal pathogens, etc.) may play a role in the pathogenesis of atherosclero-sis is molecular mimicry. Given the complexity of the mechanisms by which each microorganism may con-tribute to atherosclerosis, defining the interplay of moreinfectious agents is far more difficult because the pro-atherogenic effect of each pathogen might be ampli-fied. Clearly, continued research and a greater aware-ness will be helpful to improve our knowledge on the complex interaction between the infectious burden and atherosclerosis. | Rosa Sessa Marisa Di Pietro Simone Filardo Ombretta Turriziani | 2014 | World Journal of Clinical Cases2014,2,7: | 17 |
| 2 | Protein Domains Involved in Assembly in the Endoplasmic Reticulum Promote Vacuolar Delivery when Fused to Secretory GFP, Indicating a Protein Quality Control Pathway for Degradation in the Plant Vacuole显示文摘正确合拢和最新综合的能分泌的蛋白质的汇编被 endoplasmic 蜂窝胃的蛋白质质量控制系统监视(嗯) 。通过和象有约束力的蛋白质(BiP ) 和另外的合拢的助手那样的女伴的相互作用,质量控制赞成为降级有缺陷者蛋白质的高效的合拢和种类。为在酵母,植物,和动物识别的质量控制降级的一条主要线路被 ubiquitin/proteasome 系统,而是选择被 retrotranslocation 从 ER 组成到 cytosol 和随后的处理包含液泡的线路在酵母被识别了。在这研究,我们学习了 sGFP418 的命运,在 GFP 和涉及 phaseolin 的正确汇编并且在 unassembled 子单元的 BiP 识别的 vacuolar 蛋白质 phaseolin 的域的一种能分泌的形式之间的熔化。我们证明尽管有缺乏排序信号的 phaseolin vacuolar, sGFP418 被送到液泡并且碎裂,在被能分泌的交通禁止者 brefeldin A 禁止的一个过程。而且,在 GFP 之间的熔化和涉及玉米朊聚合的玉米存储蛋白质玉米朊的一个领域也经历类似于 sGFP418 的 translational 以后破碎。这些结果证明有通常涉及 oligomerization 的永久地暴露的序列的有缺点的能分泌的蛋白质能被能分泌的交通送到液泡。这强烈建议排序奉献给有缺点的能分泌的蛋白质的处理的机制的植物 vacuolar 的存在。 | Ombretta Foresti Francesca De Marchis Maddalena de Virgilio Eva M. Klein Sergio Arcioni Michele Bellucci Alessandro Vitale | 2008 | Molecular Plant2008,1,6: | 2 |
| 3 | The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study显示文摘 | Ombretta Salvucci Amélie Bouchard Andrea Baccarelli Jean Deschenes Guido Sauter Ronald Simon Rosella Bianchi Mark Basik | 2006 | Breast Cancer Research and Treatment2006,,3: | 2 |
| 4 | Intracellular, Intercellular, and Stromal Invasion of Gastric Mucosa, Preneoplastic Lesions, and Cancer by Helicobacter pylori显示文摘 | Vittorio Necchi Maria Elena Candusso Francesca Tava Ombretta Luinetti Ulderico Ventura Roberto Fiocca Vittorio Ricci Enrico Solcia | 2007 | Gastroenterology2007,,3: | 2 |
| 5 | Insulin-like growth factor-1 is associated with bone formation markers, PTH and bone mineral density in healthy premenopausal women显示文摘 | Silvano Adami Alessandra Zivelonghi Vania Braga Elena Fracassi Davide Gatti Maurizio Rossini Fabio M. Ulivieri Ombretta Viapiana | 2009 | Bone2009,,1: | 1 |
| 6 | Molecular Signature in HCV-Positive Lymphomas显示文摘 | Valli De Re Laura Caggiari Marica Garziera Mariangela De Zorzi Ombretta Repetto Domenico Sansonno | 2012 | Clinical and Developmental Immunology2012,,: | 1 |
| 7 | The contribution of cell phenotype to the behavior of gastric cancer显示文摘 | Enrico Solcia Catherine Klersy Alessandro Vanoli Federica Grillo Rachele Manca Francesca Tava Ombretta Luinetti Roberto Fiocca | 2013 | Gastric Cancer2013,,4: | 1 |
| 8 | Vitamin extraction by analyticalsupercritical carbon dioxide显示文摘 | GIUSEPPE PERRETTI OMBRETTA MARCONI LUIGI MONTANARI | 2003 | Journal of the American OilChemists Society2003,6,80: | 1 |
| 9 | GKLF in thymus epithelium as a developmentally regulated element of thymocyte-stroma cross-talk显示文摘 | Maddalena Panigada Simona Porcellini Francesca Sutti Luisa Doneda Ombretta Pozzoli G.Giacomo Consalez Maria Guttinger Fabio Grassi | 1999 | Mechanisms of Development1999,,1: | 1 |
| 10 | Histologic changes in type A chronic atrophic gastritis indicating increased risk of neuroendocrine tumor development: the predictive role of dysplastic and severely hyperplastic enterochromaffin-like cell lesions显示文摘 | Alessandro Vanoli Stefano La Rosa Ombretta Luinetti Catherine Klersy Rachele Manca Costanza Alvisi Sandro Rossi Erminio Trespi Adriano Zangrandi Fausto Sessa Carlo Capella Enrico Solcia | 2013 | Human Pathology2013,,9: | 1 |
| 11 | Myocardial infarction induces embryonic reprogramming of epicardial c-kit + cells: Role of the pericardial fluid显示文摘 | Federica Limana Chiara Bertolami Antonella Mangoni Anna Di Carlo Daniele Avitabile David Mocini Pina Iannelli Roberta De Mori Carlo Marchetti Ombretta Pozzoli Carlo Gentili Antonella Zacheo Antonia Germani Maurizio C. Capogrossi | 2009 | Journal of Molecular and Cellular Cardiology2009,,4: | 1 |
| 12 | Essential Roles of EphB Receptors and EphrinB Ligands in Endothelial Cell Function and Angiogenesis显示文摘 | Ombretta Salvucci Giovanna Tosato | 2012 | Advances in Cancer Research2012,,: | 1 |
| 13 | The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study 显示文摘 | Ombretta S Amelie B Guido S | 2006 | Breast Cancer Res Treat2006,97,3: | 1 |
| 14 | Polyphasic characterization of bacterial community infresh cut salads 显示文摘 | Cinzia Lucia Randazzo Giovanna Ombretta Scifb FilippoTomaselli | 2009 | International Journal of Food Microbiology2009,128,: | 1 |
| 15 | Regulation of endothelial cell branching morphogenesis by endogenous chemokine stroma derived factor显示文摘 | Ombretta S Lei Y Sabrina V | 2002 | Blood2002,99,: | 1 |
| 16 | The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study显示文摘 | Ombretta Salvucci Amélie Bouchard Andrea Baccarelli Jean Deschenes Guido Sauter Ronald Simon Rosella Bianchi Mark Basik | 2006 | Breast Cancer Research and Treatment2006,,3: | 1 |
| 17 | Template-Based Generation of Multimedia Presentations显示文摘 | Augusto Celentano Ombretta Gaggi | 2003 | International Journal of Software Engineering and Knowledge Engineering (S0218-1940)2003,13,4: | 1 |
| 18 | Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1显示文摘 | Ombretta S Lei Y Sabrina V | 2002 | Blood2002,99,: | 1 |
| 19 | Targeted proteomics to identify cadmium-induced protein modifications in Glomus mosseae-inoculated pea roots显示文摘 | Ombretta Repetto Gwenaelle Bestel-Corre Eliane Dumas-Gaudot | 2003 | New Phytol2003,157,: | 1 |
| 20 | Fat-soluble vitamin extraction by analytical supercritical carbon dioxide显示文摘 | Giuseppe Perretti Ombretta Marconi Luigi Montanari Paolo Fantozzi | 2003 | Journal of the American Oil Chemists’ Society2003,,7: | 1 |