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| 1 | 全球食品和饲料链中生物毒素早期预警、监测和毒性评估的挑战和解决方案显示文摘确保世界人口不断增长下的食品供应安全和保障是巨大和紧迫的需求。然而,全球农业和食品行业仍易受植物、藻类,尤其是真菌产生的生物毒素污染问题的挑战;随着全球变暖和极端天气事件频发,这些有毒代谢产物的发生愈发难以预测。为了提升食品和饲料链中生物毒素的预警、监测和毒性评估方法,总结在各个科学领域和方法中创新所需的多学科、多部门互补能力,具体包括使用卫星和无人机成像的大数据方法、便携式监测设备以及使用蛋白质组学和转录组学对(新兴)生物毒素进行(联合)毒性测试。 | Rudolf Krska Eskola Mari Berthiller Franz Nielen Michel Oswald Isabelle Elliott Chris McNerney Oonagh BotanaLuis Miguel MalachováAlexandra | 2021 | 粮油食品科技2021，29，6： | 2 |
| 2 | The transition from medical student to junior doctor : today's experiences of Tomorrow's Doctors 显示文摘 | Nicola B Oonagh C Jon A | 2010 | Med Educ2010，，44： | 1 |
| 3 | Antibacterial activity of the contact and complement systems is blocked by SIC, a protein secreted by streptococcus pyogenes显示文摘 | INGA-MARIA F OONAGH S PER AKESSON | 2011 | J Biol Chem2011，286，： | 1 |
| 4 | DMRT1 expression during gonadal differentiation and spermatogenesis in the rainbow trout, Oncorhynchus mykiss显示文摘 | Oriane Marchand Marina Govoroun Helena D’Cotta Oonagh McMeel Jean-Jacques Lareyre Alain Bernot Vincent Laudet Yann Guiguen | 2000 | BBA - Gene Structure and Expression2000，，1： | 1 |
| 5 | Plant-insect coevolution and inhibition of acetylcholinesterase显示文摘 | M. F. Ryan Oonagh Byrne | 1988 | Journal of Chemical Ecology1988，，10： | 1 |
| 6 | Magnesium sulfate suppresses inflammatory responses by human umbilical vein endothelial cells (HuVECs) through the NFκB pathway显示文摘 | Burton Rochelson Oonagh Dowling Nadav Schwartz Christine N. Metz | 2006 | Journal of Reproductive Immunology2006，，： | 1 |
| 7 | Dietary intake in patients with chronic pancreatitis:A systematic review and meta-analysis显示文摘BACKGROUND A progressive reduction in the secretion of pancreatic enzymes in patients with chronic pancreatitis(CP)results in malabsorption and ultimate malnutrition.However,the pathogenesis of malnutrition is multifactorial and other factors such as chronic inflammation,alcohol excess and poor dietary intake all contribute.Patients may restrict their dietary intake due to poor appetite or to avoid gastrointestinal symptoms and abdominal pain.Whilst up to half of patients with chronic pancreatitis are reportedly malnourished,the dietary intake of patients with CP is relatively understudied and has not been systematically reviewed to date.AIM To perform a systematic review and meta-analysis of the dietary intakes of patients with CP compared to healthy controls,and to compare the dietary intake of patients with alcohol-related CP and non-alcohol-related CP.METHODS A systematic literature search was performed using EMBASE,MEDLINE,and Cochrane review on studies published between 1946 and August 30th,2019.Adult subjects with a diagnosis of CP who had undergone dietary assessment were included in the systematic review(qualitative analysis).Studies on patients with other pancreatic diseases or who had undergone pancreatic surgery were not included.Studies comparing the dietary intake of patients with CP to that of healthy controls were included in the meta-analysis(quantitative analysis).Metaanalysis was performed using Review Manager 5.3.Newcastle Ottawa Scale(NOS)was used to assess quality of studies.RESULTS Of 6715 studies retrieved in the search,23 were eligible for qualitative analysis while 12 were eligible for quantitative analysis.In the meta-analysis,the total energy(calorie)intake of patients with CP was similar to that of healthy controls[mean difference(MD):171.3;95%confidence interval(CI):-226.01,568.5;P=0.4],however patients with CP consumed significantly fewer non-alcohol calories than controls[MD:-694.1;95%CI:-1256.1,(-132.1);P=0.02].CP patients consumed more protein,but carbohydrate and fat intakes did not differ significantly.Those with alcohol-related CP consumed more mean(standard deviation)calories than CP patients with a non-alcohol aetiology[2642(1090)kcal and 1372(394)kcal,respectively,P=0.046],as well as more protein,fat,but not carbohydrate.CONCLUSION Although patients with CP had similar calorie intake to controls,studies that analysed the contribution of alcohol to energy intake showed that patients with CP consumed fewer non-alcohol calories than healthy controls.A high calorie intake,made up to a large degree by alcohol,may in part contribute to poor nutritional status in CP. | Qurat Ul Ain Yasir Bashir Linda Kelleher David M Bourne Suzanne M Egan Jean McMahon Laura Keaskin Oonagh M Griffin Kevin C Conlon Sinead N Duggan | 2021 | World Journal of Gastroenterology2021，27，34： | 1 |
| 8 | Global Challenges and Solutions in the Early Warning,Monitoring and Toxicity Assessment of Biotoxins in the Food and Feed Chain显示文摘There is a massive and urgent need to ensure safety and security of the food supply of the world´s growing population.However,global agriculture and food industries continue to be vulnerable to problems of contamination with biotoxins produced by plants,algae and particularly by fungi;with global warming and extreme weather events making the occurrence of these toxic metabolites even more unpredictable.In this paper we summarize the multidisciplinary,multi-sectoral complementary competencies needed to innovate in various scientific fields and approaches,so strongly needed to develop improved early warning,monitoring and toxicity assessment of biotoxins in the food and feed chain.These include big data approaches using satellite and drone images,portable monitoring devices and(combined)toxicity testing of(emerging)biotoxins using proteomics and transcriptomics. | Rudolf Krska Eskola Mari Berthiller Franz Nielen Michel Oswald Isabelle Elliott Chris McNerney Oonagh BotanaLuis Miguel MalachováAlexandra | 2021 | 粮油食品科技2021，29，6： | 0 |
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