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| 1 | Endoscopy vs surgery in the treatment of early gastric cancer:Systematic review显示文摘AIM: To report a systematic review,establishing the available data to an unpublished 2a strength of evidence,better handling clinical practice.METHODS: A systematic review was performed using MEDLINE,EMBASE,Cochrane,LILACS,Scopus and CINAHL databases. Information of the selected studies was extracted on characteristics of trial participants,inclusion and exclusion criteria,interventions(mainly,mucosal resection and submucosal dissection vs surgical approach) and outcomes(adverse events,different survival rates,mortality,recurrence and complete resection rates). To ascertain the validity of eligible studies,the risk of bias was measured using the Newcastle-Ottawa Quality Assessment Scale. The analysis of the absolute risk of the outcomes was performed using the software Rev Man,by computingrisk differences(RD) of dichotomous variables. Data on RD and 95%CIs for each outcome were calculated using the Mantel-Haenszel test and inconsistency was qualified and reported in χ2 and the Higgins method(I2). Sensitivity analysis was performed when heterogeneity was higher than 50%,a subsequent assay was done and other findings were compiled.RESULTS: Eleven retrospective cohort studies were selected. The included records involved 2654 patients with early gastric cancer that filled the absolute or expanded indications for endoscopic resection. Threeyear survival data were available for six studies(n = 1197). There were no risk differences(RD) after endoscopic and surgical treatment(RD = 0.01,95%CI:-0.02-0.05,P = 0.51). Five-year survival data(n = 2310) showed no difference between the two groups(RD = 0.01,95%CI:-0.01-0.03,P = 0.46). Recurrence data were analized in five studies(1331 patients) and there was no difference between the approaches(RD = 0.01,95%CI:-0.00-0.02,P = 0.09). Adverse event data were identified in eight studies(n = 2439). A significant difference was detected(RD =-0.08,95%CI:-0.10--0.05,P < 0.05),demonstrating better results with endoscopy. Mortality data were obtained in four studies(n = 1107). There was no difference between the groups(RD =-0.01,95%CI:-0.02-0.00,P = 0.22).CONCLUSION: Three-,5-year survival,recurrence and mortality are similar for both groups. Considering complication,endoscopy is better and,analyzing complete resection data,it is worse than surgery. | André Kondo Eduardo Guimaraes Hourneaux de Moura Wanderley Marques Bernardo Osmar Kenji Yagi Diogo Turiani Hourneaux de Moura Eduardo Turiani Hourneaux de Moura José Gon?alves Pereira Bravo Kendi Yamazaki Paulo Sakai | 2015 | World Journal of Gastroenterology2015，21，46： | 12 |
| 2 | Ectopic expression of homeodomain protein CDX2 in intestinal metaplasia and carcinomas of the stomach显示文摘 | Yun-Qing Bai Hiroshi Yamamoto Yoshimitsu Akiyama Hiroyuki Tanaka Touichirou Takizawa Morio Koike Osmar Kenji Yagi Kiyoshi Saitoh Kimiya Takeshita Takehisa Iwai Yasuhito Yuasa | 2002 | Cancer Letters2002，，1： | 2 |
| 3 | Thyroid carcinoma during childhood and adolescence 显示文摘 | Osmar M Carlos AL Luiz Eduardo P | 2005 | Endocrinologist2005，15，1： | 1 |
| 4 | Can the Interpedicular Distance Reliably Assess the Severity of Thoracolumbar Burst Fractures?显示文摘 | Maria Fernanda Silber Caffaro Osmar Avanzi | 2012 | Spine2012，，4： | 1 |
| 5 | Building Virtual Web Views显示文摘 | | 2001 | Data and Knowledge Engineering2001，，39： | 1 |
| 6 | Illumination Invariance and Object Model in Content-based Image and Video Retrieval显示文摘 | Li Zenian Osmar R Z Zinovi T | 1999 | Journal of Visual Communication and Image Representation1999，10，3： | 1 |
| 7 | Histological evolution of hepatitis C virus infection after renal transplantation显示文摘 | Silvia Naomi Oliveira Uehara Christini Takemi Emori Patrícia da Silva Fucuta Pereira Renata M. Perez José Osmar Medina Pestana Valéria Pereira Lanzoni Ivonete Sandra Souza e Silva Antonio Eduardo Benedito Silva Maria Lucia Cardoso Gomes Ferraz | 2012 | Clin Transplant2012，，6： | 1 |
| 8 | Associative Classifiers for Medical image 显示文摘 | Maria- Luiza Antonie Osmar R Zaiane | 2003 | Mining Multimedia and Canplex Data2003，27，： | 1 |
| 9 | Characterization of Mo-MnO catalyst for propane oxidative dehydrogenation显示文摘 | Luis E Cadus Osmar Ferretti | 2002 | Appl Catal A: General2002，233，12： | 1 |
| 10 | Associative Clas- sifters for Medical image 显示文摘 | Maria- Luiza Antonie Osmar R Zaiane | 2003 | Mining Multimedia and Complex Data2003，27，： | 1 |
| 11 | Development of a fast multiresidue method for the determination of pesticides in dry samples (wheat grains, flour and bran) using QuEChERS based method and GC–MS显示文摘 | Diana I. Kolberg Osmar D. Prestes Martha B. Adaime Renato Zanella | 2010 | Food Chemistry2010，，4： | 1 |
| 12 | Thyroid carcinoma during childhood and adolescence 显示文摘 | Osmar M Carlos AL Luiz Eduardo P | 2005 | Endocrinologist2005，15，1： | 1 |
| 13 | Clustering spatial data in the presence of obstacles a density-based approach 显示文摘 | Osmar R Ziane Chi-Hoon Lee | 2002 | IEEE2002，，： | 1 |
| 14 | Multimedia data mining for the second time 显示文摘 | OSMAR R Z SIMEON J S | 2002 | SIGKDD Explorations2002，3，2： | 1 |
| 15 | Thyroid carcinoma During childhood and Adolescence 显示文摘 | Osmar M Carlos AL Luiz Eduardo P | 2005 | Endocrinologist2005，15，1： | 1 |
| 16 | Obstructive Sleep Apnea and P300 Evoked Auditory Potential显示文摘 | Carlos Henrique Martins Ney de Castro Orozimbo Alves Costa Filho Osmar Mesquita de Souza Neto | 2011 | Brazilian Journal of Otorhinolaryngology2011，，6： | 1 |
| 17 | gastric carcinoma in a 13-year old girl显示文摘 | Fernanda Deutsch Bruno Zilberstern Osmar Kenji Yagi etal | 2004 | Gastric can-cer2004，7，3： | 1 |
| 18 | Electrophysiologic characteristics of human atrial muscle in paroxysmal atrial fibrillation显示文摘 | Kunitake H Osmar AC Akihiko S | 1996 | Am Heart J1996，131，8： | 1 |
| 19 | A Framework for Enforcing Privacy in Mining Frequent Patterns显示文摘 | Stanley R M Oliveira Osmar R Z | 2002 | Technical Report2002，6，： | 1 |
| 20 | Antibacterial Peptides from Plants: What They Are and How They Probably Work显示文摘 | Patrícia Barbosa Pelegrini Rafael Perseghini del Sarto Osmar Nascimento Silva Octávio Luiz Franco Maria Fátima Grossi-de-Sa Stefano Gianni | 2011 | Biochemistry Research International2011，，： | 1 |
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