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		题名	作者	年代	出处	被引量
	1	AATYK is a Novel Regulator of Oligodendrocyte Differentiation and Myelination显示文摘Oligodendrocytes(OLs) are myelinating glial cells that form myelin sheaths around axons to ensure rapid and focal conduction of action potentials. Here, we found that an axonal outgrowth regulatory molecule, AATYK(apoptosis-associated tyrosine kinase), was up-regulated with OL differentiation and remyelination. We therefore studied its role in OL differentiation. The results showed that AATYK knockdown inhibited OL differentiation and the expression of myelin genes in vitro. Moreover, AATYKdeficiency maintained the proliferation status of OLs but did not affect their survival. Thus, AATYK is essential for the differentiation of OLs.	Chunxia Jiang Wanqing Yang Zhihong Fan Peng Teng Ruyi Mei Junlin Yang Aifen Yang Mengsheng Qiu Xiaofeng Zhao	2018	Neuroscience Bulletin2018，34，3：	2
	2	Inhibition of fatty acid synthase suppresses osteosarcoma cell invasion and migration via downregulation of the PI3K/Akt signaling pathway in vitro显示文摘	LIU Zhili MAO Jianhua PENG Aifen	2013	Mol Med Rep2013，7，2：	1
	3	TAPP1 inhibits the differentiation of oligodendrocyte precursor cells via suppressing the Mek/Erk pathway显示文摘Oligodendrocytes(OLs) are glial cells that form myelin sheaths around axons in the central nervous system(CNS).Loss of the myelin sheath in demyelinating and neurodegenerative diseases can lead to severe impairment of movement.Understanding the extracellular signals and intracellular factors that regulate OL differentiation and myelination during development can help to develop novel strategies for enhancing myelin repair in neurological disorders.Here,we report that TAPP1 was selectively expressed in differentiating OL precursor cells(OPCs).TAPP1 knockdown promoted OL differentiation and myelin gene expression in culture.Conversely,over-expression of TAPP1 in immature OPCs suppressed their differentiation.Moreover,TAPP1 inhibition in OPCs altered the expression of Erk1/2 but not AKT.Taken together,our results identify TAPP1 as an important negative regulator of OPC differentiation through the Mek/Erk signaling pathway.	Yidan Chen Ruyi Mei Peng Teng Aifen Yang Xuemei Hu Zunyi Zhang Mengsheng Qiu Xiaofeng Zhao	2015	Neuroscience Bulletin2015，31，5：	1
	4	Maternal urinary bisphenol A levels and infant low birth weight: A nested case–control study of the Health Baby Cohort in China显示文摘	Wenqian Huo Wei Xia Yanjian Wan Bin Zhang Aifen Zhou Yiming Zhang Kai Huang Yingshuang Zhu Chuansha Wu Yang Peng Minmin Jiang Jie Hu Huailong Chang Bing Xu Yuanyuan Li Shunqing Xu	2015	Environment International2015，，：	1
	5	Mitochondrial 12S rRNA variants in 1642 Han Chinese pediatric subjects with aminoglycoside-induced and nonsyndromic hearing loss显示文摘	Jianxin Lu Zhiyuan Li Yi Zhu Aifen Yang Ronghua Li Jing Zheng Qin Cai Guanghua Peng Wuwei Zheng Xiaowen Tang Bobei Chen Jianfu Chen Zhisu Liao Li Yang Yongyan Li Junyan You Yu Ding Hong Yu Jindan Wang Dongmei Sun Jianyue Zhao Ling Xue Jiying Wang Min-Xin	2010	Mitochondrion2010，，4：	1

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