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| 1 | A numerical study of macro-mesoscopic mechanical properties of gangue backfill under biaxial compression显示文摘Based on the Particle Flow Code(PFC^(2D)) program,we set up gangue backfill models with different gangue contents and bond strength,and studied the stress-strain behaviours,the pattern of shear band and force chains,motion and fragmentation of particles under biaxial compression.The results show that when the bond strength or contents of gangue are high,the peak strength is high and the phenomena of post-peak softening and fluctuation are obvious.When gangue contents are low,the shape of the shear band is symmetrical and most strong force chains transfer in soil particles.With an increase in gangue content,the shape of the shear band becomes irregular and the majority of strong force chains turn to transfer in gangue particles gradually,most of which distribute along the axial direction.When the gangue content is higher than 50%,the interconnectivity of strong force chains decreases gradually:at the same time,the strong force chains become tilted and the stability of the system tends to decrease.With an increase in external loading,the coordination numbers of the system increase at first and then decrease and the main pattern of force chains changes into columnar from annular.However,after the forming of the advantageous shear band,the force chains external to the shear band maintain their columnar shape while the inner ones bend obviously.As a result,annular force chains form. | Huang Zhimin Ma Zhanguo Zhang Lei Gong Peng Zhang Yankun Liu Fei | 2016 | International Journal of Mining Science and Technology2016，26，2： | 8 |
| 2 | Single-Crystalline In Ga As Nanowires for Room-Temperature High-Performance Near-Infrared Photodetectors显示文摘In Ga As is an important bandgap-variable ternary semiconductor which has wide applications in electronics and optoelectronics. In this work, single-crystal In Ga As nanowires were synthesized by a chemical vapor deposition method.Photoluminescence measurements indicate the In Ga As nanowires have strong light emission in near-infrared region. For the first time, photodetector based on as-grown In Ga As nanowires was also constructed. It shows good light response over a broad spectral range in infrared region with responsivity of 6.5×10~3 AW^(-1) and external quantum efficiency of 5.04×10~5%. This photodetector may have potential applications in integrated optoelectronic devices and systems. | Huang Tan Chao Fan Liang Ma Xuehong Zhang Peng Fan Yankun Yang Wei Hu Hong Zhou Xiujuan Zhuang Xiaoli Zhu Anlian Pan | 2016 | Nano-Micro Letters2016，8，1： | 6 |
| 3 | Feature extraction method of hyperspectral scattering images for prediction of total viable count in pork meat显示文摘This study aimed to investigate the capabilities of hyperspectral scattering imaging in tandem with Gaussian function,Exponential function and Lorentzian function for rapid and nondestructive determination of total viable count(TVC)in pork meat.Two batches of fresh pork meat was purchased from a local market and stored at 10°C for 1-9 d.Totally 60 samples were used,and several samples were taken out randomly for hyperspectral scattering imaging and conventional microbiological tests on each day of the experiments.The functions of Gaussian,Exponential and Lorentzian were employed to model the hyperspectral scattering profiles of pork meat,and good fitting results were obtained by all three functions between 455 nm and 1000 nm.The Lorentzian function performed best for fitting the hyperspectral scattering profiles of pork meat compared with other functions.Both principal component regression(PCR)and partial least squares regression(PLSR)methods were performed to establish the prediction models.Among all the developed models,the models developed using parameters CE(scattering width parameter of Exponential function)and CL(scattering width parameter of Lorentzian function)by PLSR method gave superior results for predicting pork meat TVC,with RV and RMSEV of 0.92,0.59 log CFU/g,and 0.91,0.61 log CFU/g,respectively.In addition,based on the improved hyperspectral scattering system,parameter c which represented the scattering widths in all three functions gave more accurate prediction results,regardless of the modeling methods(PCR or PLSR).The obtained results demonstrated that hyperspectral scattering imaging combined with the presented data analysis algorithm can be a powerful tool for evaluating the microbial safety of meat in the future. | Tao Feifei Peng Yankun Li Yongyu | 2015 | International Journal of Agricultural and Biological Engineering2015，8，4： | 5 |
| 4 | Shortwave infrared hyperspectral imaging for detection of pH value in Fuji apple显示文摘pH value is regarded as one of the most important attributes that affect sensory characteristics and edible quality of apple.The objective of the research was to explore the feasibility of applying shortwave infrared hyperspectral imaging system to detect the pH value of apple.A shortwave infrared hyperspectral imaging system was developed over the wavelength region of 1000-2500 nm and used to acquire hyperspectral images of apple samples.After reflectance calibration,mean reflectance spectral was calculated by averaging the intensity of all pixels within the roundness region of interest(ROI).Synergy interval partial least squares(siPLS)algorithms as an effective multivariable method was conducted on the calibration of regression model to estimate the pH value in Fuji apple.The performance of the final model was back-evaluated according to root mean square error of calibration(RMSEC)and correlation coefficient(Rc)in calibration set,and tested in prediction set.The optimal prediction siPLS model was obtained with correlation coefficient(Rp)of 0.8474 and mean square error of prediction(RMSEP)of 0.0398.The results indicated that shortwave infrared hyperspectral imaging combined with siPLS chemometrics could be an accurate and fast method for nondestructive prediction of pH value in Fuji apple. | Guo Zhiming Huang Wenqian Chen Liping Peng Yankun Wang Xiu | 2014 | International Journal of Agricultural and Biological Engineering2014，7，2： | 3 |
| 5 | Hepatitis B virus evades immune recognition via RNA adenosine deaminase ADAR1-mediated viral RNA editing in hepatocytes显示文摘HBV is considered as a“stealth”virus that does not invoke interferon(IFN)responses;however,the mechanisms by which HBV bypasses innate immune recognition are poorly understood.In this study,we identified adenosine deaminases acting on RNA 1(ADAR1),which is a key factor in HBV evasion from IFN responses in hepatocytes.Mechanically,ADAR1 interacted with HBV RNAs and deaminated adenosine(A)to generate inosine(I),which disrupted host immune recognition and thus promoted HBV replication.Loss of ADAR1 or its deficient deaminase activity promoted IFN responses and inhibited HBV replication in hepatocytes,and blocking the IFN signaling pathways released the inhibition of HBV replication caused by ADAR1 deficiency.Notably,the HBV X protein(HBx)transcriptionally promoted ADAR1 expression to increase the threshold required to trigger intrinsic immune activation,which in turn enhanced HBV escape from immune recognition,leading to persistent infection.Supplementation with 8-azaadenosine,an ADAR1 inhibitor,efficiently enhanced liver immune activation to promote HBV clearance in vivo and in vitro.Taken together,our results delineate a molecular mechanism by which HBx promotes ADAR1-derived HBV immune escape and suggest a targeted therapeutic intervention for HBV infection. | Liyuan Wang Yang Sun Xiaojia Song Zehua Wang Yankun Zhang Ying Zhao Xueqi Peng Xiaodong Zhang Chunyang Li Chengjiang Gao Nailin Li Lifen Gao Xiaohong Liang Zhuanchang Wu Chunhong Ma | 2021 | Cellular & Molecular Immunology2021，18，8： | 2 |
| 6 | D609 protects retinal pigmented epithelium as a potential therapy for age-related macular degeneration显示文摘Accumulated oxidative damage may lead to irreversible retinal pigmented epithelium(RPE)cell death,which is considered to be the primary cause of dry age-related macular degeneration(AMD),leading to blindness in the elderly.However,an effective therapy for this disease is lacking.Here,we described a robust high-content screening procedure with a library of 814 protective compounds and found that D609 strongly protected RPE cells from sodium iodate(SI)-induced oxidative cell death and prolonged their healthy survival.D609 effectively attenuated excessive reactive oxygen species(ROS)and prevented severe mitochondrial loss due to oxidative stress in the RPE cells.Surprisingly,the potent antioxidative effects of D609 were not achieved through its own reducibility but were primarily dependent on its ability to increase the expression of metallothionein.The injection of this small water-soluble molecule also showed an explicit protective effect of the RPE layer in an SI-induced AMD mouse model.These findings suggested that D609 could serve as a novel antioxidative protector of RPE cells both in vitro and in vivo and unveiled a novel antioxidative mechanism of D609,which may ultimately have clinical applications for the treatment of AMD. | Bowen Wang Li Wang Sijie Gu Yankun Yu Huaxing Huang Kunlun Mo He Xu Fanzhu Zeng Yichen Xiao Lulu Peng Chunqiao Liu Nan Cao Yizhi Liu Jin Yuan Hong Ouyang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 2 |
| 7 | Potential prediction of the microbial spoilage of beef using spatially resolved hyperspectral scattering profiles显示文摘 | Yankun Peng Jing Zhang Wei Wang Yongyu Li Jianhu Wu Hui Huang Xiaodong Gao Weikang Jiang | 2010 | Journal of Food Engineering2010，，2： | 1 |
| 8 | Hyperspectral scattering for assessing peach fruit firmness显示文摘 | LU Renfu PENG Yankun | 2006 | Biosystems Engineering2006，93，2： | 1 |
| 9 | Hyperspectral scattering for assessing peach fruit firmness显示文摘 | Lu Renfu Peng Yankun | 2006 | Biosystems Engineering2006，93，2： | 1 |
| 10 | Simultaneous determination of tenderness and Escherichia coli contamination of pork using hyperspectral scattering technique显示文摘 | Feifei Tao Yankun Peng Yongyu Li Kuanglin Chao Sagar Dhakal | 2011 | Meat Science2011，，3： | 1 |
| 11 | Detection of chlorpyrifos in apples using gold nanoparticles based on surface enhanced Raman spectroscopy显示文摘In this study,gold nanoparticles(AuNPs)were synthesized for rapid and sensitive characterization and quantification of chlorpyrifos in apples.Min-max signal adaptive zooming and second derivative transformation method were adopted to pre-process Raman spectral signal.The min-max signal adaptive zooming method showed a higher correlation coefficient than derivative transformation when developing linear calibration curve between chlorpyrifos pesticide and Raman spectral peak intensity.The present method had a high reproducibility with the relative standard deviation less than 15%.Regression models showed a good linear relationship(R=0.962)between intensity of characteristic spectral peaks(at 677 cm-1)and chlorpyrifos concentration on whole apples ranging from 0.13 mg/kg to 7.59 mg/kg.The application of surface enhancement Raman spectroscopy(SERS)detected chlorpyrifos pesticide to the detection limit of 0.13 mg/kg,which can be applied further for lower concentration in the future.The method presented in this study can provide a way-out for detection of pesticide residue in whole apple to trace amount. | Zhai Chen Li Yongyu Peng Yankun Xu Tianfeng | 2015 | International Journal of Agricultural and Biological Engineering2015，8，5： | 1 |
| 12 | Analys is of spatially resolved hyper- spectral scattering images for assessing apple fruit firmness and soluble solids content显示文摘 | Peng Yankun Lu Renfu | 2008 | Postharvest Biology and Technology2008，48，1： | 1 |
| 13 | Potential prediction of the microbial spoilage of beef using spatially resolved hyperspectral scattering profiles显示文摘 | Yankun Peng Jing Zhang Wei Wang Yongyu Li Jianhu Wu Hui Huang Xiaodong Gao Weikang Jiang | 2010 | Journal of Food Engineering2010，，2： | 1 |
| 14 | Improving apple fruit firmness predictions by effective correction of multispectral scattering images显示文摘 | Yankun Peng Renfu Lu | 2006 | Postharvest Biology and Technology2006，，3： | 1 |
| 15 | Hyperspectral scattering for assessing peach fruit firmness显示文摘 | Lu Renfu Peng Yankun | 2006 | Biosystems Engineering2006，93，2： | 1 |
| 16 | Improving apple fruit firmness predictions by effective correction of multispectral scattering images显示文摘 | Peng Yankun Lu R | 2006 | Postharvest biology and technology2006，41，3： | 1 |
| 17 | Hyperspectral scattering for assessing peach fruit firmness 显示文摘 | Lu Renfu Peng Yankun | 2006 | Biosystems Engi- neering2006，93，2： | 1 |
| 18 | Potential prediction of the microbial spoilage of beef using spatially resolved hyperspectral scattering profiles显示文摘 | Yankun Peng Jing Zhang Wei Wang Yongyu Li Jianhu Wu Hui Huang Xiaodong Gao Weikang Jiang | 2010 | Journal of Food Engineering2010，，2： | 1 |
| 19 | Prediction of apple fruit firmness and soluble solids content using characteristics of multispectral scattering images显示文摘 | Yankun Peng Renfu Lu | 2007 | Journal of Food Engineering2007，，2： | 1 |
| 20 | Prediction of beef quality attributes using VIS/NIR hyperspectral scattering imaging technique显示文摘 | Jianhu Wu Yankun Peng Yongyu Li Wei Wang Jingjing Chen Sagar Dhakal | 2011 | Journal of Food Engineering2011，，2： | 1 |
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