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| 1 | Parameter sensitivity and inversion analysis of a concrete faced rock-fill dam based on HS-BPNN algorithm显示文摘Considering the complex nonlinear relationship between the material parameters of a concrete faced rock-fill dam(CFRD) and its displacements, the harmony search(HS) algorithm is used to optimize the back propagation neural network(BPNN), and the HS-BPNN algorithm is formed and applied for the inversion analysis of the parameters of rock-fill materials. The sensitivity of the parameters in the Duncan and Chang's E-B model is analyzed using the orthogonal test design. The case study shows that the parameters φ0, K, Rf, and Kb are sensitive to the deformation of the rock-fill dam and the inversion analysis for these parameters is performed by the HS-BPNN algorithm. Compared with the traditional BPNN, the HS-BPNN algorithm exhibits the advantages of high convergence precision, fast convergence rate, and strong stability. | SUN PengMing BAO TengFei GU ChongShi JIANG Ming WANG Tian SHI ZhongWen | 2016 | Science China(Technological Sciences)2016,59,9: | 9 |
| 2 | Composition variations of the Sinian-Cambrian sedimentary rocks in Hunan and Guangxi and their tectonic significance显示文摘This paper reports the geochemical and zircon U-Pb dating data of the Sinian to Cambrian low-grade metamorphic rocks in the Miaoer Mountain area,Guangxi and the Jinjiling area,Hunan Province.Petrographic and geochemical features indicate that protoliths of these metamorphic rocks are clastic sedimentary rocks with medium weathering,which were formed in the passive continental margin.Geochemistry and zircon U-Pb ages indicate that the Sinian and Cambrian sedimentary rocks in the Jinjiling area have similar detritus components,which are characterized by abundant Grenvillian detrital zircons,suggesting a close affinity with the Cathaysia Block.The Cambrian sedimentary rocks in the Miaoer Mountain area have similar geochemistry and zircon geochronology to those in the Jinjiling area,showing an affinity with the Cathaysia Block.However,the Sinian sedimentary rocks in the Miaoer Mountain area show different geochemical features from the Cambrian sedimentary rocks and those in the Jinjiling area,and are characterized by abundant 840–700 Ma detrital zircons and less^2.0 Ga ones,showing a close affinity with the Yangtze Block.These variations suggest that the Jinjiling area continuously accepted the fragments from the Cathaysia from the Sinian to the Cambrian,whereas the provenance of the Miaoer Mountain sedimentary basin changed from the Yangtze Block to the Cathaysia Block during this interval.This change implies a tectonic movement,which caused the further sinking of the basin in the Miaoer Mountain area and northwestward transferring of the basin center before the Middle Cambrian,so that the Miaoer Mountain basin received the detritus from the Cathaysia Block in the Middle Cambrian.This fact also proves that the Yangtze and Cathaysia blocks have converged at least in Middle Cambrian,and the southwestern boundary between them is located between the Miaoer Mountain and Jinjiling areas. | WANG PengMing YU JinHai SUN Tao SHI Yu CHEN PeiRong ZHAO KuiDong CHEN WeiFeng LIU Qian | 2013 | Science China Earth Sciences2013,56,11: | 6 |
| 3 | Solute clusters-promoted strength-ductility synergy in Al-Sc alloy显示文摘Sc solute clusters with a high number density were produced in an Al-0.3 wt.%Sc alloy when aged at250℃,while fine Al_(3)Sc precipitates were predominantly formed in the same alloy aged at 300℃.The alloy strengthened by Sc solute clusters displayed higher yield strength and simultaneously greater ductility than its counterpart strengthened by Al_(3)Sc precipitates.This clearly demonstrates a superior strengthductility synergy promoted by the Sc solute clusters in Al-Sc alloys.The effects of Al_(3)Sc precipitates and Sc solute clusters on ductility were discussed in comparison by using a micromechanics fracture model.Since the Sc clusters were stabilized at 250℃,the Al-Sc alloys strengthened by Sc solute clusters should find extensive application fields within a wide temperature range,due to their high temperature resistance. | Chong Yang Pengming Cheng Baoan Chen Jinyu Zhang Gang Liu Jun Sun | 2022 | Journal of Materials Science & Technology2022,,1: | 3 |
| 4 | Clinical significance of extended high-risk human papillomavirus genotyping and viral load in cervical cancer and precancerous lesions显示文摘Persistent infections with specific high-risk human papillomavirus(HR-HPV)strains are the leading cause of cervical cancer and precancerous lesions.HPV-16 and HPV-18 are associated with more than 70%of cervical cancer.However,with recent widespread vaccination efforts against cervical cancer,the infection rates of HPV-16 and HPV-18 have decreased across all age groups,while the infection rates of other HR-HPV strains have increased.The non-16/18 HR-HPV strains play an important role in cervical lesions.These strains can be identified with extended genotyping,and the 2019 American Society for Colposcopy and Cervical Pathology(ASCCP)guidelines recommended an HPV-based testing to assess the risk of cervical disease in patients.We reviewed and analyzed the clinical benefits of applying extended HR-HPV genotyping,which was published by the International Agency for Research on Cancer(HPV-16,18,31,33,35,39,45,51,52,56,58,59,66,and 68),to cervical cancer screening.This review concluded that cervical cancer screening needs to include extended HR-HPV genotyping.The examination of extended HR-HPV genotyping in cervical intraepithelial lesions and cervical cancers can help guide clinical practices. | Pingping Su Jincheng Ma Lirui Yu Shuting Tang Pengming Sun | 2023 | Gynecology and Obstetrics Clinical Medicine2023,3,1: | 2 |
| 5 | Expression of estrogen receptor-related receptors, a subfamily of orphan nuclear receptors, as new tumor biomarkers in ovarian cancer cells显示文摘 | Pengming Sun Jalid Sehouli Carsten Denkert Alexander Mustea Dominique K?nsgen Ines Koch Lihui Wei Werner Lichtenegger | 2005 | Journal of Molecular Medicine2005,,6: | 1 |
| 6 | Electron-ion collider in China显示文摘Lepton scattering is an established ideal tool for studying inner structure of small particles such as nucleons as well as nuclei.As a future high energy nuclear physics project,an Electron-ion collider in China(EicC)has been proposed.It will be constructed based on an upgraded heavy-ion accelerator,High Intensity heavy-ion Accelerator Facility(HIAF)which is currently under construction,together with a new electron ring.The proposed collider will provide highly polarized electrons(with a po-larization of 80%)and protons(with a polarization of 70%)with variable center of mass energies from 15 to 20 GeV and the luminosity of(2–3)×1033 cm^(−2)·s^(−1).Polarized deuterons and Helium-3,as well as unpolarized ion beams from Carbon to Uranium,will be also available at the EicC.The main foci of the EicC will be precision measurements of the structure of the nucleon in the sea quark region,including 3D tomography of nucleon;the partonic structure of nuclei and the parton interaction with the nuclear environment;the exotic states,especially those with heavy flavor quark contents.In addition,issues fundamental to understanding the origin of mass could be addressed by measurements of heavy quarkonia near-threshold production at the EicC.In order to achieve the above-mentioned physics goals,a hermetical detector system will be constructed with cutting-edge technologies.This document is the result of collective contributions and valuable inputs from experts across the globe.The EicC physics program complements the ongoing scientific programs at the Jefferson Laboratory and the future EIC project in the United States.The success of this project will also advance both nuclear and particle physics as well as accelerator and detector technology in China. | Daniele PAnderle Valerio Bertone Xu Cao Lei Chang Ningbo Chang Gu Chen Xurong Chen Zhuojun Chen Zhufang Cui Lingyun Dai Weitian Deng Minghui Ding Xu Feng Chang Gong Longcheng Gui Feng-Kun Guo Chengdong Han Jun He Tie-Jiun Hou Hongxia Huang Yin Huang KrešImir KumeričKi LPKaptari Demin Li Hengne Li Minxiang Li Xueqian Li Yutie Liang Zuotang Liang Chen Liu Chuan Liu Guoming Liu Jie Liu Liuming Liu Xiang Liu Tianbo Liu Xiaofeng Luo Zhun Lyu Boqiang Ma Fu Ma Jianping Ma Yugang Ma Lijun Mao Cédric Mezrag HervéMoutarde Jialun Ping Sixue Qin Hang Ren Craig DRoberts Juan Rojo Guodong Shen Chao Shi Qintao Song Hao Sun PawełSznajder Enke Wang Fan Wang Qian Wang Rong Wang Ruiru Wang Taofeng Wang Wei Wang Xiaoyu Wang Xiaoyun Wang Jiajun Wu Xinggang Wu Lei Xia Bowen Xiao Guoqing Xiao Ju-Jun Xie Yaping Xie Hongxi Xing Hushan Xu Nu Xu Shusheng Xu Mengshi Yan Wenbiao Yan Wencheng Yan Xinhu Yan Jiancheng Yang Yi-Bo Yang Zhi Yang Deliang Yao Zhihong Ye Peilin Yin C-PYuan Wenlong Zhan Jianhui Zhang Jinlong Zhang Pengming Zhang Yifei Zhang Chao-Hsi Chang Zhenyu Zhang Hongwei Zhao Kuang-Ta Chao Qiang Zhao Yuxiang Zhao Zhengguo Zhao Liang Zheng Jian Zhou Xiang Zhou Xiaorong Zhou Bingsong Zou Liping Zou | 2021 | Frontiers of physics2021,16,6: | 1 |
| 7 | Molecular targeted therapy of gynecological malignanttumors: the development and challenge, from laboratory toclinic显示文摘More and more molecular drugs based on targeted therapy have been utilized in the treatment of gynecologic cancer,especially in ovarian cancer.In this article,we systematically review the current targeted therapeutic trials running in clinic.Large,randomized trials have been conducted in the treatment of ovarian cancer,endometrial cancer and cervical cancer by using small molecule,antisense,mutational gene as well as antibodies.Other planned or ongoing trials currently targeted at molecular markers which may play important roles in gynecological carcinogenesis and progression suggest that combination chemotherapy with molecular targeted therapy will ultimately be an important option. | Pengming SUN Jalid SEHOULI Lihui WEI | 2009 | Frontiers of Medicine2009,3,3: | 0 |
| 8 | Trichomonas vaginalis and human papillomavirus:Association with the microbiota and burden on the cervix显示文摘Trichomoniasis and HPV infection are common non-viral and viral sexually transmitted diseases worldwide.Emerging evidence shows that the female genital tract and its microbiota are greatly affected by these pathogens.However,the relationship between Trichomonas vaginalis,the vaginal microbiome,and High-risk(HR)-HPV infection is complex and multifaceted.Studies have proven that concurrent infections of HIV and HPV increase the risk of cervical cancer.With this basis,a question arises:How does the concurrent infection of trichomonas vaginalis and HPV affect genital tract health?Does this concurrent infection enhance or inhibit the development of cervical lesions?This review aims to bring light to these questions.This review also covers the association of trichomonas vaginalis and HPV with the microbiota of the genital tract. | Kelvin Stefan Osafo Wenyu Lin Binhua Dong Pengming Sun | 2023 | Gynecology and Obstetrics Clinical Medicine2023,3,4: | 0 |