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| 1 | Dynamic tubulation of mitochondria drives mitochondrial network formation显示文摘 | Chong Wang Wanqing Du Qian Peter Su Mingli Zhu Peiyuan Feng Ying Li Yichen Zhou Na Mi Yueyao Zhu Dong Jiang Senyan Zhang Zerui Zhang Yujie Sun Li Yu | 2015 | Cell Research2015,25,10: | 8 |
| 2 | AlxGa1-xN for solar-blind UV detectors 显示文摘 | Peter Sandvik Kan Mi Fatemeh Shahedipour | 2001 | Journal of Crystal Growth2001,231,: | 1 |
| 3 | The role of chemotherapy in the management of Nasopharyngeal carcinoma显示文摘 | Chan Peter MI Teo | 1998 | J Cancer1998,82,: | 1 |
| 4 | CD40 is consrirutively expressed on platelets and provides a novel mechanism for platelet activation 显示文摘 | Inwald DP McDowall A Peters MI | 2003 | Cir Res2003,92,: | 1 |
| 5 | Innate and acquired immtmity in atherosclerosis显示文摘 | Christoph JB Mi KC Peter XS | 2002 | Natur Med2002,8,11: | 1 |
| 6 | Innate and acquired immunity in atherosclerosis显示文摘 | Christoph J Binder Mi -Kyung Chang Peter X Shaw | 2002 | Natur Medicine2002,8,11: | 1 |
| 7 | Innate and acquired immunity in atherosclerosis显示文摘 | Christoph JB Mi KC Peter XS etal | 2002 | Natur Med2002,8,11: | 1 |
| 8 | Pay-it-forward gonorrhea and chlamydia testing among men who have sex with men in China:a study protocol for a three-arm cluster randomized controlled trial显示文摘Background:Gonorrhea and chlamydia testing rates are poor among Chinese men who have sex with men(MSM).A quasi-experimental study suggested that a pay-it-forward strategy increased dual gonorrhea/chlamydia testing among MSM.Pay-it-forward offers an individual a gift(e.g.,a free test)and then asks the same person if they would like to give a gift to another person.This article reports the protocol of a randomized controlled trial to evaluate dual gonorrhea/chlamydia test uptake and other outcomes among MSM in three arms-a pay-it-forward arm,a pay-what-you-want arm,and a standard of care arm.Methods:Three hundred MSM will be recruited at three HIV testing sites in Guangzhou and Beijing.Testing sites include two hospital-based MSM sexually transmitted diseases clinics and one MSM community-based organization.Eligible participants will be born biologically male,aged 16 years or older,reporting previous anal sex with another man,having never participated in the pay-it-forward program,without previous gonorrhea and chlamydia testing in the past 12 months,and residing in China.Following a cluster randomized design,every cluster of ten participants will be randomly allocated into one of three arms:(1)a pay-it-forward arm in which men are offered free gonorrhea and chlamydia testing and then asked whether they would like to donate('pay it forward')toward testing for future testers;(2)a pay-what-you-want arm in which men are offered free testing and told to decide how much to pay after receiving the test;(3)a standard of care arm in which men can pay the full price for dual gonorrhoea and chlamydia testing.The primary outcome is dual gonorrhoea/chlamydia testing as verified by administrative records.Secondary outcomes include incremental cost per test,incremental cost per diagnosis,community connectedness,and social cohesion.Primary outcome will be calculated for each arm using intention-to-treat and compared using one-sided 95%confidence intervals with a margin of 20%increase defined as superiority.Discussion:This study will examine the pay-it-forward strategy in comparison to the standard of care in improving test uptake for gonorrhea and chlamydia.We will leverage the cluster randomized controlled trial to provide scientific evidence on the potential effect of pay-it-forward.Findings from this study will shed light on novel intervention methods for increasing preventive health service utilization and innovate ways to finance it among communities.Trial registration:ClinicalTrials.gov,NCT03741725.Registered on 12 November 2018. | Tiange P.Zhang Fan Yang Weiming Tang Marcus Alexander Laura Forastiere Navin Kumar Katherine Li Fei Zou Ligang Yang Guodong Mi Yehua Wang Wenting Huang Amy Lee Weizan Zhu Peter Vickerman Dan Wu Bin Yang Nicholas A.Christakis Joseph D.Tucker | 2019 | Infectious Diseases of Poverty2019,8,4: | 1 |
| 9 | Innate and acquired immunity in atherosclerosis 显示文摘 | Christoph JB Mi KC Peter XS | 2002 | Natur Meal2002,8,11: | 1 |
| 10 | Nano-fibrous scaffolding promotes osteoblast differentiation and biomineralization显示文摘 | Kyung Mi Woo Ji-Hae Jun Victor J. Chen Jihye Seo Jeong-Hwa Baek Hyun-Mo Ryoo Gwan-Shik Kim Martha J. Somerman Peter X. Ma | 2006 | Biomaterials2006,,2: | 1 |
| 11 | Interleukin-4 but not interleukin-10 protects against spontaneous and recurrent type 1 diabetes by activated CDldrestricted invariant natural killer T-cells 显示文摘 | Mi QS Dalam L Peter Z | 2004 | Diabetes2004,53,5: | 1 |
| 12 | Significance of proximal biliary dilatation in patients with anastomotie strictures after liver transplantation显示文摘 | St Peter S Rodriquez-Davalos MI Rodriguez-Luna HM | 2004 | Dig Dis Sci2004,49,78: | 1 |
| 13 | Tacrolimus as a liver flush solution to ameliorate the effects of ischemia/ reperfusion injury following liver transplantation 显示文摘 | St Peter SD Post DJ Rodriguez-Davalos MI | 2003 | Liver Transpl2003,9,2: | 1 |
| 14 | The effects of UV-B irradiation on the corneal endothelium 显示文摘 | Riley MV Susan S Peters MI | 1987 | Curr Eye Res1987,6,8: | 1 |
| 15 | Significance of proximal biliary dilatation in patients with anastomotic strictures after liver transplantation显示文摘 | Peter SS Rodriquez-Davalos MI Rodriguez-Luna HM | 2004 | Dig Dis Sci2004,49,7: | 1 |
| 16 | Maternal use of hydroxychloro- quine is associated with a reduced risk of recurrent anti-ssa/ro associ- ated cardiac manifestations of neonatal lupus 显示文摘 | Peter MI Nathalie CC Cecilia P | 2012 | Circulation2012,126,1: | 1 |
| 17 | Regulation of corneal endothelial barrier function by adenosine, cyclic AMP, and protein kinases显示文摘 | Riley MV Winkler BS Starnes CA Peters MI Dang L | 1998 | Invest Ophthalmol Vis Sci1998,39,11: | 1 |
| 18 | Nano-fibrous scaffolding architecture selectively enhances protein adsorption contributing to cell attachment显示文摘 | Woo Kyung Mi Chen Victor J Ma Peter X | 2003 | J Biomed Mater Res2003,67,: | 1 |
| 19 | VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway显示文摘Although VEGF-B was discovered as a VEGF-A homolog a long time ago,the angiogenic effect of VEGF-B remains poorly understood with limited and diverse findings from different groups.Notwithstanding,drugs that inhibit VEGF-B together with other VEGF family members are being used to treat patients with various neovascular diseases.It is therefore critical to have a better understanding of the angiogenic effect of VEGF-B and the underlying mechanisms.Using comprehensive in vitro and in vivo methods and models,we reveal here for the first time an unexpected and surprising function of VEGF-B as an endogenous inhibitor of angiogenesis by inhibiting the FGF2/FGFR1 pathway when the latter is abundantly expressed.Mechanistically,we unveil that VEGF-B binds to FGFR1,induces FGFR1/VEGFR1 complex formation,and suppresses FGF2-induced Erk activation,and inhibits FGF2-driven angiogenesis and tumor growth.Our work uncovers a previously unrecognized novel function of VEGF-B in tethering the FGF2/FGFR1 pathway.Given the anti-angiogenic nature of VEGF-B under conditions of high FGF2/FGFR1 levels,caution is warranted when modulating VEGF-B activity to treat neovascular diseases. | Chunsik Lee Rongyuan Chen Guangli Sun Xialin Liu Xianchai Lin Chang He Liying Xing Lixian Liu Lasse DJensen Anil Kumar Harald FLanger Xiangrong Ren Jianing Zhang Lijuan Huang Xiangke Yin JongKyong Kim Juanhua Zhu Guanqun Huang Jiani Li Weiwei Lu Wei Chen Juanxi Liu Jiaxin Hu Qihang Sun Weisi Lu Lekun Fang Shasha Wang Haiqing Kuang Yihan Zhang Geng Tian Jia Mi Bi-Ang Kang Masashi Narazaki Aaron Prodeus Luc Schoonjans David MOrnitz Jean Gariepy Guy Eelen Mieke Dewerchin Yunlong Yang Jing-Song Ou Antonio Mora Jin Yao Chen Zhao Yizhi Liu Peter Carmeliet Yihai Cao Xuri Li | 2023 | Signal Transduction and Targeted Therapy2023,8,9: | 0 |
| 20 | Fur glowing under ultraviolet:in situ analysis of porphyrin accumulation in the skin appendages of mammals显示文摘Examples of photoluminescence(PL)are being reported with increasing frequency in a wide range of organisms from diverse ecosystems.However,the chemical basis of this PL remains poorly defined,and our understanding of its potential ecological function is still superficial.Among mammals,recent analyses have identified free-base por-phyrins as the compounds responsible for the reddish ultraviolet-induced photoluminescence(UV-PL)observed in the pelage of springhares and hedgehogs.However,the localization of the pigments within the hair largely remains to be determined.Here,we use photoluminescence multispectral imaging emission and excitation spec-troscopy to detect,map,and characterize porphyrinic compounds in skin appendages in situ.We also document new cases of mammalian UV-PL caused by free-base porphyrins in distantly related species.Spatial distribution of the UV-PL is strongly suggestive of an endogenous origin of the porphyrinic compounds.We argue that reddish UV-PL is predominantly observed in crepuscular and nocturnal mammals because porphyrins are photodegradable.Con-sequently,this phenomenon may not have a specific function in intra-or interspecific communication but rather represents a byproduct of potentially widespread physiological processes. | Séverine L.D.TOUSSAINT Jasper PONSTEIN Mathieu THOURY Rémi MÉTIVIER Daniela C.KALTHOFF Benoît HABERMEYER Roger GUILARD Steffen BOCK Peter MORTENSEN Sverre SANDBERG Pierre GUERIAU Eli AMSON | 2023 | Integrative Zoology2023,18,1: | 0 |