|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。 | 刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B | 2020 | 中华高血压杂志2020，28，3： | 22 |
| 2 | Satellite sensor image classification using cascaded architecture of neural fuzzy network显示文摘 | Lin C T Lee Y C Pu P H | 2000 | IEEE Transactions on Geoscience and Remote Sensing2000，38，2： | 2 |
| 3 | Effects of potassium aspartare and magnesium on ventricular arrhythmia in ischemia- reperfusion rabbit heart 显示文摘 | PU J ZHANG C QUAN X | 2008 | J Huazhong Univ Sci Technolog Med Sci2008，28，5： | 1 |
| 4 | Summary reports of research on alkali-activated slag显示文摘 | Pu X C Gan C C Wang S D | 1988 | Cement and Concrete1988，，8： | 1 |
| 5 | Effects of moistructure of glycerol plasticized soy protein显示文摘 | Pu C Li N Z Fei F C | 2005 | Macromol Biosci2005，5，： | 1 |
| 6 | Evidence of nanocrystalline semiconducting graphene monoxide during thermal reduction of graphene oxide in vacuum显示文摘 | Mattson E C Pu H Cui S | 2011 | ACS nano2011，5，： | 1 |
| 7 | Characterization of carbapenemases, extended spectrum β-1actamases, quinolone resistance and amin- oglycoside resistance determinants in carbapenem-non-susceptible Escherichia coli from a teaching hospital in Chongqing, Southwest China显示文摘 | Zhang C Xu X Pu S | 2014 | Infect Genet Evol2014，27，： | 1 |
| 8 | Thermal resistance of VCSEL′s bonded to integrated circuits显示文摘 | PU R WILMSEN C W GEIB K M | 1999 | IEEE Photonics Technology Letters1999，11，12： | 1 |
| 9 | The effects of antisenseAKT2RNA on the inhibition of malignant glioma cellgrowth in vitro and in vivo显示文摘 | Pu P Kang C Li J | 2006 | J Neurooncol2006，76，1： | 1 |
| 10 | Laparoscopic versus open pyeloplasty for ureteropelvic junction obstruction in children:a systematic review and meta-analysis显示文摘 | Mei H Pu J Yang C | 2011 | J Endourol2011，25，5： | 1 |
| 11 | Growth and characterization of InGaN blue LED structure on Si (111)by MOCVD显示文摘 | Mo C L Fang W Q Pu Y | 2005 | JCrystGrowth2005，285，： | 1 |
| 12 | Downregulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth 显示文摘 | Pu P Zhang Z Kang C | 2009 | Cancer Gene Ther2009，16，4： | 1 |
| 13 | Impact of three application methods on the field efficacy of a Beauveria bassiana-based mycoinsecticide against the false-eye leafhopper, Empoasca vitis (Homoptera: Cicadellidae) in the tea canopy 显示文摘 | Pu X Y Feng M G Shi C H | 2005 | Crop Protection2005，24，2： | 1 |
| 14 | An in vitro study on the suppressive effect of glioma cell growth induced by plasmid-based small interference RNA (siRNA) targeting human epidermal growth factor receptor显示文摘 | Kang C S Pu P Y Li Y H | 2005 | J Neurooncol2005，74，3： | 1 |
| 15 | Isolation and characterization of AaWRKY1, an Artemisia annua transcription factor that regulates the amorpha-4, 11-diene synthase gene, a key gene of artemisinin biosynthesis 显示文摘 | Ma D M Pu G B Lei C Y | 2009 | Plant CellPhysiol2009，50，12： | 1 |
| 16 | Hydrophilicmodification of poly (ether sulfone) ultrafiltration membranesurface by self-assembly of T1O2 nanoparticles 显示文摘 | Luo M L Zhao J Q Tang W Pu C S | 2005 | Applied Surface Science2005，249，： | 1 |
| 17 | A Ca^2+ signal is found up stream of cytochrome crelease during apoptosis in HeLa cells显示文摘 | Pu Y Luo K Q Chang D C | 2002 | Biochem Biophys Res Commun2002，299，5： | 1 |
| 18 | The impact of group velocity on frequency-hopping optical code division multiple access system显示文摘 | ZUO C MA W H PU H T LIN J T | 2001 | Lightwave Technology2001，19，10： | 1 |
| 19 | PI3K/PTEN/AKT/mTOR path- way genetic variation predicts toxicity and distant progression in lung cancer patients receiving platinmn-hased chemotherapy 显示文摘 | Pu X Hildebrandt MA Lu C | 2011 | Lung Cancer2011，71，1： | 1 |
| 20 | Climate sensitivity of the Xiao Dongkemadi glacier in the Tanggula Pass 显示文摘 | WANG N L YAO T D Pu J C | 1996 | Cryosphere1996，18，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员