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| 1 | Architectural Design Concept of Dongting Lake Museum显示文摘Architectural design of Dongting Lake Museum takes 'River dolphin ripples in the Dongting Lake' as the theme, tries to integrate into the local wetland environment and ecological resources of the Dongting Lake, in order to realize the dream of 'making a great museum for the most gorgeous lake'. The overall layout follows the concept of 'coexistence of real and virtual, integration of exterior and interior', and the architectural image symbolizes 'the river dolphin ripples', which is extremely harmonious in the whole natural environment. The design integrates planning, building, landscape and interior spaces, adopts technical means and ecological green to integrate the building into the environment, and presents us a tremendous ecological wetland museum that floats on the lake like a fish, an islet, a sail or a hill. | GUO Weihong WANG Xinyu CHEN Wendong MAO Yalong PEI Wenxiang QI Shuaijie ZHANG Shuyuan | 2017 | Journal of Landscape Research2017，9，3： | 0 |
| 2 | Was Wuhan the early epicenter of the COVID-19 pandemic?——a critique显示文摘Recently, Worobey et al.(2022) published a report entitled ‘The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic' that succinctly summarizes their study [1]. A pre-print version of this study had earlier elicited a series of highprofile media coverages [2,3]. All these reports deliver a social-political message that the Huanan market is the epicenter of COVID-19. | Yanan Cao Lingling Chen Hua Chen Yupeng Cun Xiaofeng Dai Hongli Du Feng Gao Fengbiao Guo Yalong Guo Pei Hao Shunmin He Shunping He XiongLei He Zheng Hu Boon-Peng Hoh Xin Jin Qian Jiang Qinghua Jiang Asifullah Khan Hong-Zhi Kong Jinchen Li Shuai Cheng Li Ying Li Qiang Lin Jianquan Liu Qi Liu Jian Lu Xuemei Lu Shujin Luo Qinghua Nie Zilong Qiu Tieliu Shi Xiaofeng Song Jianzhong Su Sheng-ce Tao Chaolong Wang Chuan-Chao Wang Guo-Dong Wang Jiguang Wang Qi Wu Shaoyuan Wu Shuhua Xu Yu Xue Wenjun Yang Zhaohui Yang Kai Ye Yuan-Nong Ye Li Yu Fangqing Zhao Yiqiang Zhao Weiwei Zhai Dandan Zhang Liye Zhang Houfeng Zheng Qi Zhou Tianqi Zhu Ya-ping Zhang | 2023 | National Science Review2023，10，4： | 0 |
| 3 | Poly-dopamine, poly-levodopa, and poly-norepinephrine coatings: Comparison of physico-chemical and biological properties with focus on the application for blood-contacting devices显示文摘Thanks to its simplicity,versatility,and secondary reactivity,dopamine self-polymerized coatings(pDA)have been widely used in surface modification of biomaterials,but the limitation in secondary molecular grafting and the high roughness restrain their application in some special scenarios.Therefore,some other catecholamine coatings analog to pDA have attracted more and more attention,including the smoother poly-norepinephrine coating(pNE),and the poly-levodopa coating(pLD)containing additional carboxyl groups.However,the lack of a systematic comparison of the properties,especially the biological properties of the above three catecholamine coatings,makes it difficult to give a guiding opinion on the application scenarios of different coatings.Herein,we systematically studied the physical,chemical,and biological properties of the three catecholamine coatings,and explored the feasibility of their application for the modification of biomaterials,especially cardiovascular materials.Among them,the pDA coating was the roughest,with the largest amount of amino and phenolic hydroxyl groups for molecule grafting,and induced the strongest platelet adhesion and activation.The pLD coating was the thinnest and most hydrophilic but triggered the strongest inflammatory response.The pNE coating was the smoothest,with the best hemocompatibility and histocompatibility,and with the strongest cell selectivity of promoting the proliferation of endothelial cells while inhibiting the proliferation of smooth muscle cells.To sum up,the pNE coating may be a better choice for the surface modification of cardiovascular materials,especially those for vascular stents and grafts,but it is still not widely recognized. | Xing Tan Peng Gao Yalong Li Pengkai Qi Jingxia Liu Ru Shen Lianghui Wang Nan Huang Kaiqin Xiong Wenjie Tian Qiufen Tu | 2021 | Bioactive Materials2021，6，1： | 0 |
| 4 | The effect of Pickering emulsion adjuvants on the immune efficacy of the COVID-19 polypeptide vaccine显示文摘Pickering emulsions were prepared by phacoemulsification in an ice water bath with squalene as the oil phase and an aluminum adjuvant as the particle stabilizer.The effects of formulation and process conditions on the size and distribution of the Pickering emulsions were investigated.Pickering emulsions prepared under the optimal prescription and process conditions were mixed with a peptide antigen to obtain a peptide vaccine.The optimal prescription and process condition of the Pickering emulsion is as follows:squalene as the oil phase,ultra-pure water as the water phase with 5 mg/mL aluminum adjuvant,and an ultrasonication time of 4 min at 200 W power.BALB/c mice were immunized with the peptide vaccine,and the ability of the Pickering emulsion as an immunological adjuvant to improve the efficacy of the peptide vaccine was evaluated.Under optimal conditions,a Pickering emulsion with a small particle size(430.8 nm),uniform distribution(polydispersion index of 16.9%),and zeta potential of 31.5 mV,was obtained.Immunological results showed that the serum specific antibody level in the vaccinated group reached 1×104 after three immunizations.The proportion of CD4+T cells and CD4/CD8 cells was significantly higher(P<0.05)in the vaccinated groups than the blank control group.Further,cytokine(TNF-��)secretion decreased in the aluminum adjuvant and Pickering emulsion groups but increased in the Freund’s adjuvant group.All three vaccinated groups of mice exhibited low but detectable levels of IFN-��secretion. | Zhuanqing Huang Qi Sun Haoyuan Shi Sen Yang Yuanyuan Li Yue Ma Fei Yang Zhenwei Shi Yalong Yang Ying Zhang Hui Gong Fenghua Xu | 2023 | ChemPhysMater2023，2，3： | 0 |
| 5 | Periodic Variations of Drag Coefficient for the ANDE Spherical Satellites During its Lifetime显示文摘A drag coefficient(C_d) inversion method is introduced to study the variations of the drag coefficient for orbital satellites with spherical geometry.Drag coefficients of the four micro satellites in the Atmospheric Neutral Density Experiment(ANDE) are compiled out with this new method. The Lomb-Scargle Periodgram(LSP) analysis of the four ANDE satellites' C__d series has shown that there are obvious 5,7,9,and 27 days' period in those data.Interesting results are found through comparing the LSP analysis with series of the daily solar radio flux at 10.7cm(F_(10.7) index),the Ap index,and the daily averaged solar wind speed at 1AU.All series in the same time interval have an obvious period of about 27 days,which has already been explained as the association with the 27 days' solar rotation.The oscillating periods less than 27 days are found in series of C_D,Ap and solar wind speed at 1 AU,e.g.,the 5,7,9 days period.However,these short periods disappeared in the time series of F_(10.7) index.The same periodicities of 5,7,9 days in Ap and solar wind are presented at the same time interval during the declining phase of solar cycle 23.While in the ascending phase of solar cycle 24,these short oscillations are not so obvious as that in the declining phase of solar cycle 23.These results provide definite evidence that the C_d variations with period of 5,7 and 9 days are produced by a combination of space weather effects caused by the solar wind and geomagnetic activity. | QI Yalong LI Huijun XIANG Jie MAN Haijun | 2013 | 空间科学学报2013，33，5： | 0 |
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