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| 1 | Coinfection with influenza A virus enhances SARS-CoV-2 infectivity显示文摘The upcoming flu season in the Northern Hemisphere merging with the current COVID-19 pandemic raises a potentially severe threat to public health.Through experimental coinfection with influenza A virus(IAV)and either pseudotyped or live SARS-CoV-2 virus,we found that IAV preinfection significantly promoted the infectivity of SARS-CoV-2 in a broad range of cell types.Remarkably,in vivo,increased SARS-CoV-2 viral load and more severe lung damage were observed in mice coinfected with IAV.Moreover,such enhancement of SARS-CoV-2 infectivity was not observed with several other respiratory viruses,likely due to a unique feature of IAV to elevate ACE2 expression.This study illustrates that IAV has a unique ability to aggravate SARS-CoV-2 infection,and thus,prevention of IAV infection is of great significance during the COVID-19 pandemic. | Lei Bai Yongliang Zhao Jiazhen Dong Simeng Liang Ming Guo Xinjin Liu Xin Wang Zhixiang Huang Xiaoyi Sun Zhen Zhang Lianghui Dong Qianyun Liu Yucheng Zheng Danping Niu Min Xiang Kun Song Jiajie Ye Wenchao Zheng Zhidong Tang Mingliang Tang Yu Zhou Chao Shen Li Zhou Yu Chen Huan Yan Ke Lan Ke Xu | 2021 | Cell Research2021，31，4： | 16 |
| 2 | Frozen subduction in the Yangtze block:insights from the deep seismic profiling and gravity anomaly in east Sichuan fold belt显示文摘The Sichuan basin is the main part of the middle-upper Yangtze block, which has been experienced a long-term tectonic evolution since Archean. The Yangtze block was regarded as a stable block until the collision with the Cathaysia block in late Neoproterozoic. A new deep seismic reflection profile conducted in the eastern Sichuan fold belt(ESFB) discovered a serials of south-dipping reflectors shown from lower crust to the mantle imply a frozen subduction zone within the Yangtze block. In order to prove the speculation, we also obtain the middle-lower crustal gravity anomalies by removing the gravity anomalies induced by the sedimentary rocks and the mantle beneath the Moho, which shows the mid-lower crustal structure of the Sichuan basin can be divided into eastern and western parts. Combined with the geochronology and Aeromagnetic anomalies, we speculated the Yangtze block was amalgamated by the West Sichuan and East Sichuan blocks separated by the Huayin-Chongqing line. The frozen subduction zone subsequently shifted to a shear zone accommodated the lower crustal shortening when the decollement at the base of the Nanhua system functioned in the upper plate. | Xiaosong Xiong Rui Gao Haiyan Wang Jisheng Zhang Lianghui Guo | 2016 | Earthquake Science2016，29，2： | 7 |
| 3 | Lifetime maximization routing with network coding in wireless multihop networks显示文摘In this paper, we consider the lifetime maximization routing with network coding in wireless mul- tihop networks. We first show that lifetime maximization with network coding is different from pure routing, throughput maximization with network coding and energy minimization with network coding. Then we formulate lifetime maximization problems in three different cases of (i) no network coding, (ii) two-way network coding, and (iii) overhearing network coding. To solve these problems, we use flow augmenting routing (FA) for the first case, and then extend the FA with network coding (FANC) by using energy minimized one-hop network coding. After that, we investigate the influence of parameters of FANC, evaluate the performance of FANC with two-way and overhearing network coding schemes and compare it with that without network coding under two different power control models, namely, protocol and physical ones. The results show that the lifetime can be improved significantly by using network coding, and the performance gain of network coding decreases with the increase of flow asymmetry and the power control ability. | DING LiangHui WU Ping WANG Hao PAN ZhiWen YOU XiaoHu | 2013 | Science China(Information Sciences)2013，56，2： | 6 |
| 4 | An Improved Equalization with Real Interference Prediction Scheme of the FBMC/OQAM System显示文摘FBMC/OQAM transmission system has a better spectral efficiency than OFDM.However,its orthogonality condition is only considered in the real field.In the presence of fading channels,the real orthogonality of FBMC/OQAM might be lost,which calls for new equalization schemes.In this paper,an improved equalizer with real interference prediction(ERIP)scheme of FBMC/OQAM is proposed.We analyze the correlation between the real and the neighboring imaginary interference components taking Doppler shifts into account,and derive the improved ERIP scheme.The simulation results show that the proposed scheme can outperform the original ERIP and the one-tap equalization in time-varying multipath scenarios with an affordable complexity. | Feng Yang Yue Wang Lianghui Ding Liang Qian | 2021 | China Communications2021，18，1： | 4 |
| 5 | Microcavity top-emission perovskite light-emitting diodes显示文摘Light-emitting diodes(LEDs)based on perovskites show great potential in lighting and display applications.However,although perovskite films with high photoluminescence quantum efficiencies are commonly achieved,the efficiencies of perovskite LEDs are largely limited by the low light out-coupling efficiency.Here,we show that high-efficiency perovskite LEDs with a high external quantum efficiency of 20.2% and an ultrahigh radiant exitance up to 114.9mWcm^(−2) can be achieved by employing the microcavity effect to enhance light extraction.The enhanced microcavity effect and light outcoupling efficiency are confirmed by the study of angle-dependent emission profiles.Our results show that both the optical and electrical properties of the device need to be optimized to achieve high-performance perovskite LEDs. | Yanfeng Miao Lu Cheng Wei Zou Lianghui Gu Ju Zhang Qiang Guo Qiming Peng Mengmeng Xu Yarong He Shuting Zhang Yu Cao Renzhi Li Nana Wang Wei Huang Jianpu Wang | 2020 | Light(Science & Applications)2020，9，1： | 4 |
| 6 | The Deep Structure Feature of the Sichuan Basin and Adjacent Orogens显示文摘The basin-mountain system in the Sichuan Basin(SCB) reflects the main tectonic activity and the orogenic denudation in this region. The seismic probing work reveals the deep structure of the basin-mountain system. The seismic work was re-sampled to the Moho depth and the sedimentary thickness as well as the P-wave velocity-depth function to analyze the deep structure of the SCB and adjacent orogens. The results show two deposit centers in the SCB: the Deyang area in the west and the Nanchuan area in the east and depression uplift exists in the southwestern part of the SCB; the Moho shallowers gradually from the west to east(ca. 62-36 km deep),the South-North seismic belt(SNSB) is very distinctive: the Moho depth is much shallower(< 50 km)to the east of the SNSB, whereas it is much deeper(>50 km)to the west of the SNSB, suggesting that the SNSB rather than the Longmen Shan tectonic belt is a main Moho transition belt; the topography and the top interface of the basement have the same undulation trend when the sedimentary thickness and the Moho depth have a mirror relationship; the low velocity zone developed in the Kangdian thrust and fold belt and Songpan-Garzê belt implied a soft, weak and thick crust there showing tectonic activity in these areas. | XIONG Xiaosong GAO Rui GUO Lianghui WANG Haiyan JIANG Zhuwei | 2015 | Acta Geologica Sinica(English Edition)2015，89，4： | 3 |
| 7 | Observation and research of deep underground multi-physical fields—Huainan–848 m deep experiment显示文摘Compared with the surface,the deep environment has the advantages of allowing“super-quiet and ultra-clean”-geophysical field observation with low vibration noise and little electromagnetic interference,which are conducive to the realization of long-term and high-precision observation of multi-physical fields,thus enabling the solution of a series of geoscience problems.In the Panyidong Coal Mine,where there are extensive underground tunnels at the depth of 848 m below sea level,we carried out the first deep-underground geophysical observations,including radioactivity,gravity,magnetic,magnetotelluric,background vibration and six-component seismic observations.We concluded from these measurements that(1)the background of deep subsurface gravity noise in the long-period frequency band less than 2 Hz is nearly two orders of magnitude weaker than that in the surface observation environment;(2)the underground electric field is obviously weaker than the surface electric field,and the relatively high frequency of the underground field,greater than 1 Hz,is more than two orders of magnitude weaker than that of the surface electric field;the east-west magnetic field underground is approximately the same as that at the surface;the relatively high-frequency north-south magnetic field underground,below 10 Hz,is at least one order of magnitude lower than that at the surface,showing that the underground has a clean electromagnetic environment;(3)in addition to the highfrequency and single-frequency noises introduced by underground human activities,the deep underground space has a significantly lower background vibration noise than the surface,which is very beneficial to the detection of weak earthquake and gravity signals;and(4)the underground roadway support system built with ferromagnetic material interferes the geomagnetic field.We also found that for deep observation in the“ultra-quiet and ultra-clean”environment,the existing geophysical equipment and observation technology have problems of poor adaptability and insufficient precision as well as data cleaning problems,such as the effective separation of the signal and noise of deep observation data.It is also urgent to interpret and comprehensively utilize these high-precision multi-physics observation data. | Yun WANG Yaxin YANG Heping SUN Chengliang XIE Qisheng ZHANG Xiaoming CUI Chang CHEN Yongsheng HE Qiangqiang MIAO Chaomin MU Lianghui GUO Jiwen TENG | 2023 | Science China Earth Sciences2023，66，1： | 3 |
| 8 | Ln2Zr2O7 compounds(Ln=La,Pr, Sm, Y) with varied rare earth A sites for low temperature oxidative coupling of methane显示文摘With the objective to develop catalysts having application potential for oxidative coupling of methane (OCM) at relatively lower temperature. A series of Ln2Zr2O7 compounds with varied rare earth A sites have been prepared by a co-precipitation method. XRD and Raman have proved that pure Ln2Zr2O7 compounds have been successfully prepared for all the catalysts. By decreasing the rA/rB ratio, their crystalline structure transform from an ordered pyrochlore (La2Zr2O7) to a less ordered pyrochlore (Pr2Zr2O7 and Sm2Zr2O7) and eventually to a defective cubic fluorite phase (Y2Zr2O7). H2-TPR, O2-TPD and XPS have testified that the amount of surface active O2-species follows the order of La2Zr2O7>Pr2Zr2O7>Sm2Zr2O7 > Y2Zr2O7, which is well consistent with the reaction performance, indicating that the abundance of surface O2- sites is a critical factor influencing the reaction performance. CO2-TPD has demonstrated that a better catalyst generally possesses a larger amount of surface moderate alkaline sites, which is another factor to affect the reaction performance. It is concluded that the concerted interaction between the two types of surface active sites controls the reaction performance of the Ln2Zr2O7 catalysts. In comparison with the state-of-the art Mn/Na2WO4/SiO2, La2Zr2O7, the best catalyst, exhibits much improved reaction performance below 750 ℃. | Xiuzhong Fang Lianghui Xia Liang Peng Yuan Luo Junwei Xu Luoji Xu Xianglan Xu Wenming Liu Renyang Zheng Xiang Wang | 2019 | Chinese Chemical Letters2019，30，6： | 2 |
| 9 | Improve throughput of TCP-Vegas in multihop ad hoc networks 显示文摘 | Ding Lianghui Wang Xinbing Xu Youyun | 2008 | Computer Communications2008，31，10： | 1 |
| 10 | From bubbling to turbulent fluidization: Advanced onset of regime transition in micro-fluidized beds显示文摘 | Junwu Wang Lianghui Tan M.A. van der Hoef M. van Sint Annaland J.A.M. Kuipers | 2011 | Chemical Engineering Science2011，，9： | 1 |
| 11 | From bubbling to turbulent fluidization:advanced onset of regime transition in micro-fluidized beds 显示文摘 | Wang Junwu Tan Lianghui van der Hoef M A Annaland M van Sint Kuipers J A M | 2011 | Chemical Engineering Science2011，66，9： | 1 |
| 12 | A novel paper-based flexible ammonia gas sensor via silver and SWNT-PABS inkjet printing显示文摘 | Lianghui Huang Peng Jiang Dong Wang | 2014 | Sensors and Actuators B: Chemical2014，197，5： | 1 |
| 13 | Poly-dopamine, poly-levodopa, and poly-norepinephrine coatings: Comparison of physico-chemical and biological properties with focus on the application for blood-contacting devices显示文摘Thanks to its simplicity,versatility,and secondary reactivity,dopamine self-polymerized coatings(pDA)have been widely used in surface modification of biomaterials,but the limitation in secondary molecular grafting and the high roughness restrain their application in some special scenarios.Therefore,some other catecholamine coatings analog to pDA have attracted more and more attention,including the smoother poly-norepinephrine coating(pNE),and the poly-levodopa coating(pLD)containing additional carboxyl groups.However,the lack of a systematic comparison of the properties,especially the biological properties of the above three catecholamine coatings,makes it difficult to give a guiding opinion on the application scenarios of different coatings.Herein,we systematically studied the physical,chemical,and biological properties of the three catecholamine coatings,and explored the feasibility of their application for the modification of biomaterials,especially cardiovascular materials.Among them,the pDA coating was the roughest,with the largest amount of amino and phenolic hydroxyl groups for molecule grafting,and induced the strongest platelet adhesion and activation.The pLD coating was the thinnest and most hydrophilic but triggered the strongest inflammatory response.The pNE coating was the smoothest,with the best hemocompatibility and histocompatibility,and with the strongest cell selectivity of promoting the proliferation of endothelial cells while inhibiting the proliferation of smooth muscle cells.To sum up,the pNE coating may be a better choice for the surface modification of cardiovascular materials,especially those for vascular stents and grafts,but it is still not widely recognized. | Xing Tan Peng Gao Yalong Li Pengkai Qi Jingxia Liu Ru Shen Lianghui Wang Nan Huang Kaiqin Xiong Wenjie Tian Qiufen Tu | 2021 | Bioactive Materials2021，6，1： | 0 |
| 14 | 5-26 Capacitive-Load Isolation Techniques in Timing Detector of CSRe Internal Target显示文摘Capacitive-load isolation technique[1] was proposed to improve the stability and capacitive load ability of the timing detector system in internal target of CSRe. This technique can solve the overshoot and ringing problems of the circuit, without affecting its gain and bandwidth. By constructing the circuit model, the cause of the instability of the circuit is analyzed mathematically, and the rationality of the capacitive-load isolation techniques is proved in experiment. | Zhu Kunlu Wang Wei Yu Deyang Liu Junliang Li Lianghui Cai Xiaohong | 2015 | IMP & HIRFL Annual Report2015，，1： | 0 |
| 15 | Efficient thermal dissipation in wafer-scale heterogeneous integration of single-crystalline��β-Ga_(2)O_(3)thin film on SiC显示文摘The semiconductor,β-Ga_(2)O_(3)is attractive for applications in high power electronic devices with low conduction loss due to its ultra-wide bandgap(∼4.9 eV)and large Baliga’s figure of merit.However,the thermal conductivity of��β-Ga_(2)O_(3)is much lower than that of other wide/ultra-wide bandgap semiconductors,such as SiC and GaN,which results in the deterioration of��β-Ga_(2)O_(3)-based device performance and reliability due to self-heating.To overcome this problem,a scalable thermal management strategy was proposed by heterogeneously integrating wafer-scale single-crystalline��β-Ga_(2)O_(3)thin films on a highly thermally conductive SiC substrate.Characterization of the transferred��β-Ga_(2)O_(3)thin film indicated a uniform thickness to within±2.01%,a smooth surface with a roughness of 0.2 nm,and good crystalline quality with an X-ray rocking curves(XRC)full width at half maximum of 80 arcsec.Transient thermoreflectance measurements were employed to investigate the thermal properties.The thermal performance of the fabricated��β-Ga_(2)O_(3)/SiC heterostructure was effectively improved in comparison with that of the��β-Ga_(2)O_(3)bulk wafer,and the effective thermal boundary resistance could be further reduced to 7.5 m 2 K/GW by a post-annealing process.Schottky barrier diodes(SBDs)were fabricated on both a��β-Ga_(2)O_(3)/SiC heterostructured material and a��β-Ga_(2)O_(3)bulk wafer.Infrared thermal imaging revealed the temperature increase of the SBDs on��β-Ga_(2)O_(3)/SiC to be one quarter that on the��β-Ga_(2)O_(3)bulk wafer with the same applied power,which suggests that the combination of the��-Ga_(2)O_(3)thin film and SiC substrate with high thermal conductivity promotes heat dissipation in��β-Ga_(2)O_(3)-based devices. | Wenhui Xu Tiangui You Yibo Wang Zhenghao Shen Kang Liu Lianghui Zhang Huarui Sun Ruijie Qian Zhenghua An Fengwen Mu Tadatomo Suga Genquan Han Xin Ou Yue Hao Xi Wang | 2021 | Fundamental Research2021，1，6： | 0 |
| 16 | Reliable and broad-range layer identification of Au-assisted exfoliated large area MoS_(2)and WS_(2)using reflection spectroscopic fingerprints显示文摘The emerging Au-assisted exfoliation technique enables the production of a wealth of large-area and high-quality ultrathin two dimensional(2D)crystals.Fast,damage-free,and reliable determination of the layer number of such 2D films can greatly promote layer-dependent physical studies and device applications.Here,an optical method has been developed for simple,high throughput,and accurate determination of the layer number for Au-assisted exfoliated MoS_(2)and WS_(2)films in a broad thickness range.The method is based on quantitative analysis of layer-dependent white light reflection spectra(WLRS),revealing that the intensity of exciton-induced reflection peaks can be used as a clear indicator for identifying the layer number.The simple yet robust method will facilitate fundamental studies on layer-dependent optical,electrical,and thermal properties and device applications of 2D materials.The technique can also be readily combined with photoluminescence(PL)and Raman spectroscopies to study other layer-dependent physical properties of 2D materials. | Bo Zou Yu Zhou Yan Zhou Yanyan Wu Yang He Xiaonan Wang Jinfeng Yang Lianghui Zhang Yuxiang Chen Shi Zhou Huaixin Guo Huarui Sun | 2022 | Nano Research2022，15，9： | 0 |
| 17 | Role of oncogenic long noncoding RNA KCNQ1OT1 in colon cancer显示文摘The role of lncRNA KCNQ1 opposite strand/antisense transcript 1(KCNQ1OT1)in colon cancer involves various tumorigenic processes and has been studed widely.However,the mechanism by which it promotes colon cancer remains unclear.Retrovirnl vector pSEB61 was retroftted in established HCT116 siKCN and SW480-siKCN cells to silence KCNQ1 OT1.Cellular proliferation was measured using CCK8 assay,and flow cytometry(FCM)detected cell cydle changes.RNA sequencing(RNA Seq)analysis showed differentially expressed genes(DEGs).Gene ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment analyses were carried out to analyze enriched functions and signaling pathways.RT-qPCR,immunofluorescence,and western blotting were carried out to validate downstream gene expressions.The effects of tumorigenesis were evaluated in BALB/c nude mice by tumor xenografts.Our data revealed that the silencing of KONQ1OT1 in HCT116 and SW480 cells slowed cell growth and decreased the number of cells in the G2/M phase.RNA-Seq analysis showed the data of DEGs enriched in various GO and KEGG pathways such as DNA replication and cell cyde.RT qPCR,immunofluorescence,and western blotting confirmed downstream CCNE2 and PCNA gene expressions.HCT116 siKCN cells signifcantly suppressed tumorigenesis in BALB/c nude mice.Our study suggests that lncRNA KCNQ1OT1 may provide a promising therapeutic strategy for colon cancer. | GANG LIU LEI SHI BIN WANG ZEHUI WU HAIYUAN ZHAO TIANYU ZHAO LIANGHUI SHI | 2024 | Oncology Research2024，32，3： | 0 |
| 18 | Effects of Different Seed Coating Agents on the Quality of'Grey-matter'Hybrid Rice Seeds显示文摘[Objectives]This study was conducted to select suitable mixed seed coating agents for improving the quality of'grey-matter'hybrid rice seeds.[Methods]Three different mixed seed coating agents(A,B,C)were used to coat the seeds of two varieties(Taiyou 390 and Zhenliangyou 8612)of hybrid rice with different'grey-matter'content(5%,15%,25%),and the results were investigated and compared.[Results]The combinations of treatment B(seed coating agent A+Linong)and treatment C(Manshijin+seed coating agent A)could significantly improve indexes including seed germination potential,germination rate,seed vigor,seedling height,fibrous roots and fresh weight of the two varieties with a'grey-matter'content greater than 15%,but had no significant effects on main root length,dry weight,leaf number and tiller number,and the effects of treatment B was better than those of treatment C.That is to say,mixed seed coating agent B(seed coating agent A+Linong)was suitable for use as a seed coating agent to improve the quality of'grey-matter'seeds.[Conclusions]This study provides a reference plan for the safe use of mixed seed batches with'grey-matter'deterioration. | Yuan YUAN Manzhuo TANG Hanyu NING Lianghui JIANG Chunxia LU Yan WANG Chenzhong JIN Jie PENG Xinhua KUANG Yihong HU | 2023 | Agricultural Biotechnology2023，12，3： | 0 |
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