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| 1 | Thermal stability of LiFePO_4/C-LiMn_2O_4 blended cathode materials显示文摘Safety is important to lithium ion battery materials. The thermal stability of LiFePO_4/C-LiMn_2O_4 blended cathode materials is characterized by using TG, XRD, and SEM etc. The results show that LiFePO_4/C-LiMn_2O_4 possesses a worse thermal stability than pure spinel LiMn_2O_4 and pure olivine LiFePO_4/C. When LiFePO_4/C-LiMn_2O_4 blended cathode materials are sintered at 500°C under Ar atmosphere, the sintered cathode materials emit O_2, and appear impurity phases(Li_3PO_4, Fe_2O_3, Mn_3O_4). It is deduced that some chemical reactions take place between different materials, which leads to a worse discharge specific capacity. LiFePO_4/C-LiMn_2O_4 blended cathode materials, therefore, need to be managed and controlled strictly for the sake of thermal stability and safety. | DU YuanChao HUANG XiaoPeng ZHANG KeYu LIANG Feng LI QiuXia YAO YaoChun DAI YongNian | 2017 | Science China(Technological Sciences)2017，60，1： | 5 |
| 2 | A comparative study of proliferation and osteogenic differentiation of rat adipose-derived stem cells in β-tricalcium phosphate (β-TCP), forsterite (Mg_2SiO_4 ) and clinoenstatite (MgSiO_3)显示文摘In this study, the effects of forsterite and clinoenstatite powder extracts on the proliferation and osteogenic differentiation of rat adipose-derived stem cells (ASCs) were investigated and compared with the β-tricalcium phosphate (β-TCP) powder extracts. Methylthiazolyldiphenyl-tetrazolium bromide (MTT) assay and live-dead staining were performed to evaluate the viability and proliferation of rat ASCs. Osteogenic differentiation of rat ASCs were assayed by alkaline phosphatase (ALP) staining and ALP activity test. The expression of osteogenic marker genes (alkaline phosphatase (ALP), runt related transcription factor 2 (Runx2), collagen type Iα1 (Col1α1), secreted phosphoprotein1 (Spp1, osteopontin), integrin binding sialoprotein (Ibsp), bone gla protein (Bglap)) were detected by real-time polymerase chain reaction (PCR). The MTT assay and the live-dead staining showed that all the three ceramics possessed good cytocompatibility with rat ASCs. Furthermore, forsterite and clinoenstatite promoted the proliferation of rat ASCs compared with β-TCP. The results of the ALP activity test and the real-time PCR demonstrated that forsterite and clinoenstatite promoted the osteogenic differentiation of rat ASCs. These results suggested that forsterite and clinoenstatite are bioactive ceramics that may be used for preparation of bone tissue engineering (BTE) scaffolds. | LENG Bin JIN XiaoGang LIN QiuXia CHEN Lei WANG Yan DU ZhiYan LIN KaiLi CHANG Jiang GU XiaoMing WANG ChangYong | 2013 | Chinese Science Bulletin2013，58，24： | 2 |
| 3 | Bioluminescence imaging of caspase-3 activity in mouse liver显示文摘 | Qiuxia Fu Xiangguo Duan Shaoduo Yan Licui Wang Yong Zhou Shuaizheng Jia Juan Du Xiaohui Wang Yuhua Zhang Linsheng Zhan | 2013 | Apoptosis2013，，8： | 1 |
| 4 | The influence of chitosan hydrogel on stem cell engraftment, survival and homing in the ischemic myocardial microenvironment显示文摘 | Zhiqiang Liu Haibin Wang Yan Wang Qiuxia Lin Anning Yao Feng Cao Dexue Li Jin Zhou Cuimi Duan Zhiyan Du Yanmeng Wang Changyong Wang | 2011 | Biomaterials2011，，11： | 1 |
| 5 | Gold nanorod-based localized surface plasmon resonance biosensor for sensitive detection of hepatitis B virus in buffer, blood serum and plasma显示文摘 | Xiaohui Wang Yuan Li Huafen Wang Qiuxia Fu Jianchun Peng Yingli Wang Juan Du Yong Zhou Linsheng Zhan | 2010 | Biosensors and Bioelectronics2010，，2： | 1 |
| 6 | Response of MaHMA2 gene expression and stress tolerance to zinc stress in mulberry(Morus alba L.)显示文摘HMA2(heavy metal ATPase 2)plays a crucial role in extracellular and intracellular Zn^(2+)transport across biomembranes,maintaining ion homeostasis,and playing an important role in the normal physiological metabolism,growth,and development of plants.In our study,a novel HMA2 gene,named MaHMA2,was isolated and cloned from white mulberry(Morus alba L.).The gene sequence obtained was 1,342 bp long,with an open reading frame of 1,194 bp,encoding a protein of 397 amino acids,with a predicted molecular mass of 42.852 kD and an isoelectric point of 7.53.This protein belonged to the PIB-type ATPase transport protein family.We analyzed the expression of the MaHMA2 gene by quantitative real-time PCR.The results showed that the level of MaHMA2 gene expression decreased to a Zn concentration of 800 mg/kg.Malondialdehyde and proline levels increased and responded to increasing Zn when the MaHMA2 gene was silenced,whereas the activities of peroxidase and superoxide dismutase tended to increase in response to increasing Zn^(2+)ion stress concentrations but were lower in the gene-silenced plants.These findings suggested that the MaHMA2 gene played an active role in the tolerance response of mulberry to Zn stress. | LEI WANG QIUXIA DU YISU SHI MICHAEL ACKAH PENG GUO DANYAN ZHENG MENGMENG WU XIN JIN PEILAN LI QIAONAN ZHANG RUIXUE LI ZHI YIN MENGDI ZHAO WEIGUO ZHAO | 2022 | BIOCELL2022，46，10： | 0 |
| 7 | Transplantation of human placental chorionic plate-derived mesenchymal stem cells for repair of neurological damage in neonatal hypoxic-ischemic encephalopathy显示文摘Neonatal hypoxic-ischemic encephalopathy is often associated with permanent cerebral palsy,neurosensory impairments,and cognitive deficits,and there is no effective treatment for complications related to hypoxic-ischemic encephalopathy.The therapeutic potential of human placental chorionic plate-derived mesenchymal stem cells for various diseases has been explored.However,the potential use of human placental chorionic plate-derived mesenchymal stem cells for the treatment of neonatal hypoxic-ischemic encephalopathy has not yet been investigated.In this study,we injected human placental chorionic plate-derived mesenchymal stem cells into the lateral ventricle of a neonatal hypoxic-ischemic encephalopathy rat model and observed significant improvements in both cognitive and motor function.Protein chip analysis showed that interleukin-3 expression was significantly elevated in neonatal hypoxic-ischemic encephalopathy model rats.Following transplantation of human placental chorionic plate-derived mesenchymal stem cells,interleukin-3 expression was downregulated.To further investigate the role of interleukin-3 in neonatal hypoxic-ischemic encephalopathy,we established an in vitro SH-SY5Y cell model of hypoxic-ischemic injury through oxygen-glucose deprivation and silenced interleukin-3 expression using small interfering RNA.We found that the activity and proliferation of SH-SY5Y cells subjected to oxygen-glucose deprivation were further suppressed by interleukin-3 knockdown.Furthermore,interleukin-3 knockout exacerbated neuronal damage and cognitive and motor function impairment in rat models of hypoxic-ischemic encephalopathy.The findings suggest that transplantation of hpcMSCs ameliorated behavioral impairments in a rat model of hypoxic-ischemic encephalopathy,and this effect was mediated by interleukin-3-dependent neurological function. | Lulu Xue Ruolan Du Ning Bi Qiuxia Xiao Yifei Sun Ruize Niu Yaxin Tan Li Chen Jia Liu Tinghua Wang Liulin Xiong | 2024 | Neural Regeneration Research2024，19，9： | 0 |
| 8 | DNA damage chemotherapeutic drugs suppress basal-like breast cancer growth by down-regulating the transcription of the FOXO1-KLF5 axis显示文摘Most basal-like breast cancers(BLBCs)have a poor prognosis and high crossover with triple-negative breast cancers(TNBCs).However,approximately 50%of TNBC patients develop chemoresistance.^(1) Dexamethasone reportedly induces Krüppel-like factor 5(KLF5)and can cause docetaxel and cisplatin resistance in TNBC.A super-enhancer can maintain the transcription of KLF5. | Qiuxia Cui Jian Sun Jingping Yuan Juanjuan Li Chuanyu Yang Guangshi Du Chengang Zhou Pu Qiu Jidong Gao Yuanqi Zhang Dewei Jiang Ceshi Chen | 2024 | Genes & Diseases2024，11，1： | 0 |
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