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| 1 | The Genome of Artemisia annua Provides Insight into the Evolution of Asteraceae Family and Artemisinin Biosynthesis显示文摘Artemisia annua,通常已知的同样香甜的苦恼或 Qinghao,是到中国的一个灌木土著人并且长被用于药用的目的。A。annua 现在作为有势力抗疟药混合物的唯一的生来的来源全球性被栽培, artemisinin。这里,我们报导 A 的 1.74-gigabase 染色体的一个高质量的草稿集会。annua,高度异质接合,富于重复定序,并且包含 63 ? 226 编码蛋白质的基因,在定序的植物种类之中的最大的数字之一。我们发现了那,作为在 Asteraceae 的一些定序的染色体之一, A。annua 染色体包含对这大被子植物 clade 特定的很多基因。尤其是,扩大和编码涉及萜烯生合成的酶的基因的功能的多样化与 artemisinin biosynthetic 小径的进化一致。我们进一步由介绍那 A 的 transcriptome 揭示了。annua 发展了复杂 transcriptional 规章的网络位于 \O 下面 artemisinin 生合成。把转基因的 A 基于我们产生了的全面 genomic 和 transcriptomic 分析。artemisinin 高级的生产的 annua 线,它现在为大规模生产准备好了并且将从而帮助遇见增加 artemisinin 的全球需求的挑战。 | Qian Shen Lida Zhang Zhihua Liao Shengyue Wang Tingxiang Yan Pu Shi Meng Liu Xueqing Fu Qifang Pan Yuliang Wang Zongyou Lv Xu Lu Fangyuan Zhang Weimin Jiang Yanan Ma Minghui Chen Xiaolong Hao Ling Li Yueli Tang Gang Lv Yan Zhou Xiaofen Sun Peter E. Brodelius Jocelyn K.C. Rose Kexuan Tang | 2018 | Molecular Plant2018，11，6： | 47 |
| 2 | Homology-mediated end joining-based targeted integration using CRISPR/Cas9显示文摘 | Yao, Xuan Wang, Xing Hu, Xinde Liu, Zhen Liu, Junlai Zhou, Haibo Shen, Xiaowen Wei, Yu Huang, Zijian Ying, Wenqin Wang, Yan Nie, Yan-Hong Zhang, Chen-Chen Li, Sanlan Cheng, Leping Wang, Qifang Wu, Yan Huang, Pengyu Sun, Qiang Shi, Linyu Yang, Hui | 2017 | Cell Research2017，27，6： | 28 |
| 3 | One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs显示文摘CRISPR/Cas9 系统是一个有效编辑基因的方法,但是编辑基因的动物的多数显示出 mosaicism,与编辑仅仅在房间的部分发生。这里,我们证明那单个基因或多重基因能被 Cas9 mRNA 和多重邻近的单个指南的 RNA 的 zygotic 注射完全在老鼠和猴子胚胎击倒(spaced 10-200 bp 分开) 指向仅仅一把单个钥匙每基因的 exon。个别地在 Y 染色体上跟随八基因的指向的删除的 F0 老鼠的 Phenotypic 分析在产生猛烈老鼠表明了这条途径的坚韧性。重要地,这条途径在高效率交付完全的基因大美人(Arntl 上的 100% 并且 91% 在 Prrt2 上) 在猴子胚胎。最后,我们能在一个单个步骤产生一只完全的 Prrt2 猛烈猴子,表明在很快建立编辑基因的猴子模型的这条途径的实用性。 | Erwei Zuo Yi-Jun Cai Kui Li Yu Wei Bang-An Wang Yidi Sun Zhen Liu Jiwei Liu Xinde Hu Wei Wei Xiaona Huo Linyu Shi Cheng Tang Dan Liang Yan Wang Yan-Hong Nie Chen-Chen Zhang Xuan Yao Xing Wang Changyang Zhou Wenqin Ying Qifang Wang Ren-Chao Chen Qi Shen Guo-Liang Xu Jinsong Li Qiang Sun Zhi-Qi Xiong Hui Yang | 2017 | Cell Research2017，27，7： | 21 |
| 4 | Preliminary analysis of the hanging wall effect and velocity pulse of the 5.12 Wenchuan earthquake显示文摘A preliminary study of the PGA attenuation, hanging wall effect and velocity pulse characteristics from the 2008 Wenchuan earthquake of Ms =8.0 is described in this paper. The study was carried out through analyses in the time and frequency domains of main earthquake records. In the PGA attenuation study, records from 316 stations less than 1000 km from the surface rupture of the fault were used as a database and attenuation relationships were developed and compared with some existing relationships that are widely used in China's Mainland, Chinese Taiwan and the US. At the same time, records from 28 stations less than 100 km from the fault were used to study the hanging wall effect and velocity pulse characteristics of this earthquake based on the distribution of PGA, PGV, spectral acceleration, and the velocity pulse peak, and the results are compared with the 1999 Chi-Chi earthquake. In addition, the large PGAs of the UD components observed in this event are also discussed in this paper. From the results of the preliminary study, some conclusions are developed and suggestions for further research are proposed. | Liu Qifang and Li Xiaojun Institute of Engineering Mechanics, China Earthquake Administration, Harbin 150080, China Associate Professor Professor | 2009 | Earthquake Engineering and Engineering Vibration2009，8，2： | 11 |
| 5 | Three-dimensional simulations of strong ground motion in the Shidian basin based upon the spectral-element method显示文摘The strong motion of a small long and narrow basin caused by a moderate scenario earthquake is simulated by using the spectral-element method and the parallel computing technique.A total of five different geometrical profiles within the basin are used to analyze the generation and propagation of surface waves and their relation to the basin structures in both the time and frequency domain.The amplification effects are analyzed by the distribution of peak ground velocity(PGV)and cumulative kinetic energy(Ek) in the basin.The results show that in the 3D basin,the excitation of the fundamental and higher surface wave modes are similar to that of the 2D model.Small bowls in the basin have great influence on the amplification and distribution of strong ground motion,due to their lateral resonances when the wavelengths of the lateral surface waves are comparable to the size of the bowls.Obvious basin edge effects can be seen at the basin edge closer to the source for constructive interference between direct body waves and the basin-induced surface waves.The Ek distribution maps show very large values in small bowls and some corners in the basin due to the interference of waves propagating in different directions.A high impedance contrast model can excite more surface wave modes,resulting in longer shaking durations as well as more complex seismograms and PGV and Ek distributions. | Liu Qifang Yu Yanyan Zhang Xubin | 2015 | Earthquake Engineering and Engineering Vibration2015，14，3： | 6 |
| 6 | Up-regulation of heme oxygenase-1 by isoflurane preconditioning during tolerance against neuronal injury induced by oxygen glucose deprivation显示文摘Heme oxygenase (惊讶) 是在降级的限制率的酶他我生产胆汁颜料和碳一氧化物。HO-1 isozyme 被象热那样的许多因素导致,他我,局部缺血,和氢过氧化物。在最近的年里,装调查结果建议了那 HO-1 举办一项 neuroprotective 活动对是化学家损害。isoflurane 的 neuroprotective 角色,一通常使用麻药,很好被记录了,但是很少对包含的内在的机制被知道。最近, isoflurane 在肝被显示出到起来调整 HO-1。在这研究,我们证明 isoflurane preconditioning 支持幸存有教养是化学家由增加熬过神经原和他们的生存能力的数字的海马趾的神经原。由反向的抄写聚合酶链反应和西方的污点分析的进一步的学习证明 isoflurane preconditioning 显著地在导致的氧葡萄糖剥夺(OGD ) 增加 HO-1 表示 neuronal 损害。而且,抑制惊讶由听 protoporphyrin 的活动部分废除 isoflurane preconditioning 测量了由的保护的效果喂奶在 OGD 神经原的脱氢酶版本。这些调查结果显示对导致 OGD 的损害的 isoflurane preconditioning 的 neuroprotective 角色可能在起来调整的 HO-1 与它的角色被联系在是化学家神经原。 | Qifang Li Yesen Zhu Hong Jiang Hui Xu Heping Liu | 2008 | Acta Biochimica et Biophysica Sinica2008，40，9： | 3 |
| 7 | An MPC-based manoeuvre stability controller for full drive-by-wire vehicles显示文摘Aiming at the actuator time delay caused by the drive-by-wire technology,a novel manoeuvre stability controller based on model predictive control is proposed for full drive-by-wire vehicles.Firstly,the future vehicle dynamics are predicted by a twodegree-of-freedom vehicle model with input delay.Secondly,in order to prevent the vehicle from destabilizing due to excessive side slip angles,the determined ideal yaw rate and side slip angle are tracked simultaneously by optimizing the front wheel angle and additional yaw moment.Moreover,in order to improve the trajectory tracking ability,a side slip angle constraint determined by phase plane stability boundaries is added to the cost function.The results of Matlab and veDYNA co-simulation show that the regulated yaw rate can track the reference value well and the side slip angle decreases.Meanwhile,the trajectory tracking ability is improved obviously by compensating the time delay. | Ping WANG Ziyang LIU Qifang LIU Hong CHEN | 2019 | Control Theory and Technology2019，17，4： | 2 |
| 8 | Controllable synthe- sis of Bi2WO6 nanofibrous mat by electrospinning and enhanced visible photocatalytic degradation performances 显示文摘 | Zhao Gang Liu Suwen Lu Qifang | 2012 | Industrial & Engineering Chemistry Research2012，51，10： | 1 |
| 9 | 显示文摘 | Song Lingjun Liu Suwen Lu Qifang | 2012 | Applied Surface Science2012，258，8： | 1 |
| 10 | A new model for depicting mass flow rate characteristic of electronic expansion valves显示文摘 | LIU Jinghui CHEN Jiangping YE Qifang | 2007 | Experimental Thermal and Fluid Science2007，32，1： | 1 |
| 11 | Characteristics and origins of heavy metals in sediments from Ximen Co Lake during summer monsoon season, a deep lake on the eastern Tibetan Plateau显示文摘 | Hezhong Yuan Enfeng Liu Ji Shen Hengjie Zhou Qifang Geng Shuqing An | 2014 | Journal of Geochemical Exploration2014，，： | 1 |
| 12 | Optimization modeling method for coal-to-electricity heating load considering differential decisions显示文摘Heating by electricity rather than coal is considered one effective way to reduce environmental problems. Thus, the electric heating load is growing rapidly, which may cause undesired problems in distribution grids because of the randomness and dispersed integration of the load. However, the electric heating load may also function as an energy storage system with optimal operational control. Therefore, the optimal modeling of electric heating load characteristics, considering its randomness, is important for grid planning and construction. In this study, the heating loads of distributed residential users in a certain area are modeled based on the Fanger thermal comfort equation and the predicted mean vote thermal comfort index calculation method. Different temperatures are considered while modeling the users' heating loads. The heat load demand curve is estimated according to the time-varying equation of interior temperature. A multi-objective optimization model for the electric heating load with heat energy storage is then studied considering the demand response(DR), which optimizes economy and the comfort index. A fuzzy decision method is proposed, considering the factors influencing DR behavior. Finally, the validity of the proposed model is verified by simulations. The results show that the proposed model performs better than the traditional method. | Qifang Chen Mingchao Xia Shan Wang Hanyu Wang Wenxia Liu Zhiqiang Wang Xianglong Li Qinfei Sun Xiangzhi Niu | 2019 | Global Energy Interconnection2019，2，2： | 1 |
| 13 | Alkoxysilane functionalized polycaprolactone/polysiloxane modified epoxy resin through sol–gel process显示文摘 | Pinggui Liu Jiangxuan Song Lihua He Xingquan Liang Heyan Ding Qifang Li | 2007 | European Polymer Journal2007，，3： | 1 |
| 14 | Stress analysis of solid propellant grain based on fractional derivative Kelvin viscoelastic model显示文摘 | YAN Qifang LIU Linchao YAN Pan | 2015 | Journal of Xinyang Normal University(Natural Science Edition)2015，28，4： | 1 |
| 15 | Controllable synthesis of Bi2 WO6 nanofibrous mat by electrospinning and enhanced visible photocatalytic degradation performances显示文摘 | Gang Zhao Suwen Liu Qifang Lu Lingjun Song | 2012 | ndustrial & Engineering Chemistry Research2012，51，10： | 1 |
| 16 | Energy management of HEVs based on velocity profile optimization显示文摘Dear editor, Ecological awareness and economical reasons call for a substantial reduction of the fuel consumption of all future automobiles. One of the most realistic short-term solutions to energy saving is represented by hybrid elec trie vehicles (HEVs). Those strategies that det ermine power dist ribution within the hybrid powertrain, as well as the gearshift schedule to enhance fuel economy are often referred as energy management systems (EMSs), such as rule-based methods [1,2] and optimizationbased methods [3-5]. In optimization-based methods, although numerous constraints exist, a truly optimal fuel consumption can be achieved when the entire driving cycle is known a priori. | Lulu GUO Hong CHEN Bingzhao GAO Qifang LIU | 2019 | Science China(Information Sciences)2019，62，8： | 1 |
| 17 | Optimal Scheduling of Residential Heating, Ventilation and Air Conditioning Based on Deep Reinforcement Learning显示文摘Residential heating, ventilation and air conditioning(HVAC) provides important demand response resources for the new power system with high proportion of renewable energy. Residential HAVC scheduling strategies that adapt to realtime electricity price signals formulated by demand response program and ambient temperature can significantly reduce electricity costs while ensuring occupants' comfort. However, since the pricing process and weather conditions are affected by many factors, conventional model-based method is difficult to meet the scheduling requirements in complex environments. To solve this problem, we propose an adaptive optimal scheduling strategy for residential HVAC based on deep reinforcement learning(DRL) method. The scheduling problem can be regarded as a Markov decision process(MDP). The proposed method can adaptively learn the state transition probability to make economical decision under the tolerance violations. Specifically, the residential thermal parameters obtained by the leastsquares parameter estimation(LSPE) can provide a basis for the state transition probability of MDP. Daily simulations are verified under the electricity prices and temperature data sets, and numerous experimental results demonstrate the effectiveness of the proposed method. | Mingchao Xia Fangjian Chen Qifang Chen Siwei Liu Yuguang Song Te Wang | 2023 | Journal of Modern Power Systems and Clean Energy2023，11，5： | 0 |
| 18 | Introduction to the benchmark challenge on common rail pressure control of gasoline direct injection engines显示文摘As one of the most important actuators for gasoline direct injection technology,common rail systems provide the requested rail pressure for fuel injection.Special system characteristics,such as coupled discrete-continuous dynamic in the common rail system,limited measurable states,and time-varying engine operating conditions,impel the combination of advanced methods to obtain the desired injection pressure.Therefore,reducing the pressure fluctuation and satisfying engineering implementation have become noteworthy issues for rail pressure control(RPC)systems.In this study,the benchmark problem and the design specification of RPC proposed by 2018 IFAC E-CoSM Committee are introduced.Moreover,a common rail system model is provided to the challengers,and a traditional PI control is applied to show the problem behaviors.Finally,intermediate results of the challengers are summarized briefly. | Qifang LIU Jinlong HONG Bingzhao GAO Hong CHEN | 2019 | Control Theory and Technology2019，17，2： | 0 |
| 19 | Fluorocarbon and Hydrocarbon Benzodioxocycloalkane (C8-Cl0) End Groups: Effects on Mesomorphism显示文摘一个新班基于 benzodioxocycloalkane (C8C10 ) 液体晶体被准备。戒指(C8C10 ) 的影响作为结束组被调查。89 membered 戒指衍生物, 3a3b,展出了 nematic 阶段(N) 。具有由中胚叶发达的行为与增加戒指的尺寸被削弱。为 ? uorinated 媒介戒指(C8C10 ) 3d3f,它仅仅被发现氟化十 membered 戒指 3f 证明 LC 分阶段执行行为。与不同长度烷基组和到 polyfluoroalkyl 的烷基的变化一起的戒指尺寸的修正显著地影响了这些混合物的性质。 | Wanwan Cao Peilian Liu Hongren Chen Yaohang Zhu Rihao Chen Qifang Zhou Zhuo Zeng | 2013 | Chinese Journal of Chemistry2013，31，7： | 0 |
| 20 | Real-time energy-efficient anticipative driving control of connected and automated hybrid electric vehicles显示文摘In this paper,we propose a real-time energy-efficient anticipative driving control strategy for connected and automated hybrid electric vehicles(HEVs).Considering the inherent complexities brought about by the velocity profile optimization and energy management control,a hierarchical control architecture in the model predictive control(MPC)framework is developed for real-time implementation.In the higher level controller,a novel velocity optimization problem is proposed to realize safe and energy-efficient anticipative driving.The real-time control actions are derived through a computationally efficient algorithm.In the lower level controller,an explicit solution of the optimal torque split ratio and gear shift schedule is introduced for following the optimal velocity profile obtained from the higher level controller.The comparative simulation results demonstrate that the proposed strategy can achieve approximately 13%fuel consumption saving compared with a benchmark strategy. | Shiying Dong Hong Chen Lulu Guo Qifang Liu Bingzhao Gao | 2022 | Control Theory and Technology2022，20，2： | 0 |
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