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| 1 | Support technology for mine roadways in extreme weakly cemented strata and its application显示文摘For the engineering geology conditions of bad mine roadway roof and floor lithology in extremely weak cemented strata, the best section shape of the roadway is determined from the study of tunnel surrounding rock displacement, plastic zone and stress distribution in rectangular, circle arch and arch wall sections, respectively. Based on the mining depth and thickness of the coal seam, roadway support technology solutions with different buried depth and thickness of coal seam are proposed. Support schemes are amended and optimized in time through monitoring data of the deformation of roadway,roof separation, I-beam bracket, bolt and anchor cable force to ensure the long-term stability and security of the roadway surrounding rock and support structure. The monitoring results show that mine roadway support schemes for different buried depth and section can be adapted to the characteristics of ground pressure and deformation of the surrounding rock in different depth well, effectively control the roadway surrounding rock deformation and the floor heave and guarantee the safety of construction and basic stability of surrounding rock and support structure. | Meng Qingbin Han Lijun Qiao Weiguo Lin Dengge Fan Jiadong | 2014 | International Journal of Mining Science and Technology2014，24，2： | 23 |
| 2 | Numerical simulation study of the failure evolution process and failure mode of surrounding rock in deep soft rock roadways显示文摘Based on the safety coefficient method,which assigns rock failure criteria to calculate the rock mass unit,the safety coefficient contour of surrounding rock is plotted to judge the distribution form of the fractured zone in the roadway.This will provide the basis numerical simulation to calculate the surrounding rock fractured zone in a roadway.Using the single factor and multi-factor orthogonal test method,the evolution law of roadway surrounding rock displacements,plastic zone and stress distribution under different conditions is studied.It reveals the roadway surrounding rock burst evolution process,and obtains five kinds of failure modes in deep soft rock roadway.Using the fuzzy mathematics clustering analysis method,the deep soft surrounding rock failure model in Zhujixi mine can be classified and patterns recognized.Compared to the identification results and the results detected by geological radar of surrounding rock loose circle,the reliability of the results of the pattern recognition is verified and lays the foundations for the support design of deep soft rock roadways. | Meng Qingbin Han Lijun Xiao Yu Li Hao Wen Shengyong Zhang Jian | 2016 | International Journal of Mining Science and Technology2016，26，2： | 14 |
| 3 | Experimental study on the bolt–cable combined supporting technology for the extraction roadways in weakly cemented strata显示文摘Aiming at the characteristics of the poor steady ability, the short stable time and severe deformation behavior of weakly cemented soft surrounding rock around extraction roadway, a bolt–cable combined supporting technology was proposed. Numerical simulation was performed by using FLAC3 D software to study the effects of different supporting systems. The simulation result proves that those supporting systems have good practical values. Based on real-time monitoring and analysis of the deformation of surrounding rock and the stress of supporting structure, real time information of deformation of surrounding rock and stress state of supporting structure of extraction roadway within weakly cemented strata was obtained. Monitoring results show that large deformation and failure of surrounding rock of extraction roadway within weakly cemented strata can be effectively controlled by the bolt–cable combined supporting technology, which ensures the long-term stability and safety of surrounding rock and supporting structure. | Meng Qingbin Han Lijun Sun Jingwu Min Fengqing Feng Wei Zhou Xing | 2015 | International Journal of Mining Science and Technology2015，25，1： | 13 |
| 4 | Bolt-grouting combined support technology in deep soft rock roadway显示文摘Analyzing the mineral composition, mechanical properties and ground stress testing in surrounding rock,the study investigated the failure mechanism of deep soft rock roadway with high stress. The boltgrouting combined support system was proposed to prevent such failures. By means of FLAC3D numerical simulation and similar material simulation, the feasibility of the support design and the effectiveness of support parameters were discussed. According to the monitoring the surface and deep displacement in surrounding rock as well as bolt axial load, this paper analyzed the deformation of surrounding rock and the stress condition of the support structure. The monitor results were used to optimize the proposed support scheme. The results of field monitors demonstrate that the bolt-grouting combined support technology could improve the surround rock strength and bearing capacity of support structure, which controlled the great deformation failure and rheological property effectively in deep soft rock roadway with high stress. As a result, the long term stability and safety are guaranteed. | Chen Yanlong Meng Qingbin Xu Guang Wu Haoshuai Zhang Guimin | 2016 | International Journal of Mining Science and Technology2016，26，5： | 10 |
| 5 | Chinese herbal medicine reduces mortality in patients with severe and critical coronavirus disease 2019: a retrospective cohort study显示文摘This study aimed to evaluate the efficacy of Chinese herbal medicine(CHM)in patients with severe/critical coronavirus disease 2019(COVID-19).In this retrospective study,data were collected from 662 patients with severe/critical COVID-19 who were admitted to a designated hospital to treat patients with severe COVID-19 in Wuhan before March 20,2020.All patients were divided into an exposed group(CHM users)and a control group(non-users).After propensity score matching in a 1:1 ratio,156 CHM users were matched by propensity score to 156 non-users.No significant differences in seven baseline clinical variables were found between the two groups of patients.All-cause mortality was reported in 13 CHM users who died and 36 non-users who died.After multivariate adjustment,the mortality risk of CHM users was reduced by 82.2%(odds ratio 0.178,95%CI 0.076–0.418;P<0.001)compared with the non-users.Secondly,age(odds ratio 1.053,95%CI 1.023–1.084;P<0.001)and the proportion of severe/critical patients(odds ratio 0.063,95%CI 0.028–0.143;P<0.001)were the risk factors of mortality.These results show that the use of CHM may reduce the mortality of patients with severe/critical COVID-19. | Guohua Chen Wen Su Jiayao Yang Dan Luo Ping Xia Wen Jia Xiuyang Li Chuan Wang Suping Lang Qingbin Meng Ying Zhang Yuhe Ke An Fan Shuo Yang Yujiao Zheng Xuepeng Fan Jie Qiao Fengmei Lian Li Wei Xiaolin Tong | 2020 | Frontiers of Medicine2020，14，6： | 10 |
| 6 | Determination of full-scale pore size distribution of Gaomiaozi bentonite and its permeability prediction显示文摘Gaomiaozi(GMZ)bentonite is a potential buffer/backfill material for a deep geological disposal of highlevel radioactive waste.It has a wide pore size distribution(PSD)with sizes ranging from several nanometers to more than one hundred microns.Thus,properly characterizing the pore structures of GMZ bentonite is a challenging issue.In this study,pressure-controlled porosimetry(PCP),ratecontrolled porosimetry(RCP),and scanning electron microscopy(SEM)were used to investigate the PSD of GMZ bentonite,The results indicate that each method has its limitation,and a combined use of PCP and RCP is suitable to obtain the full-scale PSD of GMZ bentonite.Moreover,we also compared the full-scale PSD with nuclear magnetic resonance(NMR)result.It is found that there is no significant difference in the range of PSD characterization between NMR and mercury intrusion method(PCP and RCP).However,in a ce rtain range,the detection accuracy of NMR is higher than that of mercury injection method.Finally,permeability prediction based on PCP and SEM data was conducted,and both of the two methods were found to be able to predict the permeability.The combined method is effective to obtain the full-scale PSD of GMZ bentonite,which is the key to estimation of the sealing ability of bentonite buffer. | Jiangfeng Liu Shuaibing Song Xulou Cao Qingbin Meng Hai Pu Yangguang Wang Jianfeng Liu | 2020 | Journal of Rock Mechanics and Geotechnical Engineering2020，12，2： | 5 |
| 7 | Influence of dynamic pressure on deep underground soft rock roadway support and its application显示文摘Due to high ground stress and mining disturbance, the deformation and failure of deep soft rock roadway is serious, and invalidation of the anchor net-anchor cable supporting structure occurs. The failure characteristics of roadways revealed with the help of the ground pressure monitoring. Theoretical analysis was adopted to analyze the influence of mining disturbance on stress distribution in surrounding rock,and the change of stress was also calculated. Considering the change of stress in surrounding rock of bottom extraction roadway, the displacement, plastic zone and distribution law of principal stress difference under different support schemes were studied by means of FLAC3D. The supporting scheme of U-shaped steel was proposed for bottom extraction roadway that underwent mining disturbance. We carried out a similarity model test to verify the effect of support in dynamic pressure. Monitoring results demonstrated the change rules of deformation and stress of surrounding rock in different supporting schemes. The supporting scheme of U-shaped steel had an effective control on deformation of surrounding rock. The scheme was successfully applied in underground engineering practice, and achieved good technical and economic benefits. | Meng Qingbin Han Lijun Chen Yanlong Fan Jiadong Wen Shengyong Yu Liyuan Li Hao | 2016 | International Journal of Mining Science and Technology2016，26，5： | 4 |
| 8 | Portfolio selection in the enlarged Markovian Regime-switching market 显示文摘 | ZHANG Xin SIN Tak Kuen MENG Qingbin | 2010 | Society for industrial and Applied Mathematie2010，48，5： | 1 |
| 9 | Stochastic optimal control models forthe insurance company with bankruptcy return显示文摘 | Meng Qingbin Li Zhendong Wang Menghai Zhang Xin | 2013 | Applied Mathematics and Information Sciences2013，7，： | 1 |
| 10 | Aggregation of biotinylated polymeric microspheres induced by interaction with avidin显示文摘 | MENG Qingbin LI Zhanyong LI Gang | 2007 | Pure Apply Chemical2007，79，9： | 1 |
| 11 | On a risk model with dependence between claim sizes and claim intervals显示文摘 | Meng Qingbin Zhang Xin Guo Junyi | 2008 | Statistics and Probability Letters2008，78，： | 1 |
| 12 | Why Greater Cash Holdings and Short-Term Debt Simultaneously Persist? The Case of Transition Economy显示文摘这研究在现金资源和短期的债同时在样品时期上占超过 20% 全部的财产至少二连续的年的中国公司观察并且探索一个难题。这现象与社团的价值最大化的原则冲突,并且不是清楚地在社团的金融由古典理论解释了。在中国在转变经济的机构的限制的现存文学和讨论基于含意,这份报纸开发涉及在最大的股东和债权人和这思索的形成之间的机构冲突的四个假设金融结构。实验分析建议有通道动机的最大的股东寻求保持更多的现金服务他们的私人利息或列出的公司的作为结果的运作的赤字。到目的,这些公司趋于管理预定短学期债资助在年的结束暂时增加现金储备。实质上,这些公司的资产负债表上的更大的现金资源与难题联系了为潜在的债权人成为一个似是而非的信号,可能贡献供这些的短期的债列出了公司下列年。因此,思索金融结构与预定债资助和债权人的不利选择被连接。这研究在现金资源和债成熟上充实文学的溪流,并且在转变经济的上下文在在现金资源和债成熟之间的协会上在最大的股东的机构问题的影响上提供新证据。 | Lu Dai Qingbin Meng Maozhu Sun | 2015 | Frontiers of Business Research in China2015，9，2： | 0 |
| 13 | Host-guest inclusion for enhancing anticancer activity of pemetrexed against lung carcinoma and decreasing cytotoxicity to normal cells显示文摘Advanced chemotherapy strategies are in urgent demand for improving anticancer efficacy.Herein,a water-soluble pillar[6]arene(WP6 A)was used to load chemotherapeutic agent pemetrexed(PMX)by forming direct host-guest inclusion,which is beneficial for decreasing cytotoxicity of PMX on BEAS-2 B cells.NMR and florescence titration served to confirm the complexation between WP6 A and ATP with higher affinity[(5.67?0.31)x 10^(5)L/mol],favoring competitive replacement of PMX.Complexation ATP by WP6 A effectively prevented ATP from being hydrolyzed in presence of alkaline phosphatase.The formed host-guest complex was further used to block the efflux pump by cutting off energy source from ATP hydrolysis,which was accompanied with releasing PMX to produce synergistic enhancement of anticancer performance towards A549 cells.This supramolecular strategy would also be extended to other clinical chemotherapeutic agents and it was expected to provide salutary profits for cancer patients. | Junyi Chen Yahan Zhang Yadan Zhang Liang Zhao Longming Chen Yao Chai Zhao Meng Xueshun Jia Qingbin Meng Chunju Li | 2021 | Chinese Chemical Letters2021，32，10： | 0 |
| 14 | Reversing neuromuscular blocking agent decamethonium by carboxylatopillar[6]arene based on host-guest encapsulation显示文摘Neuromuscular blocking agents(NMBAs)are extensively used during anesthesia to improve surgical conditions by relaxing skeletal muscle movements.Rapid neuromuscular recovery after surgery is desirable to facilitate the recovery of muscle function and prevent residual blockade.Decamethonium(C10)is a classic NMBA,which has been restricted over the past decades ascribed to lack of a suitable antidote in clinic.Herein we used carboxylatopillar[6]arene(CP6A)to reverse neuromuscular blocker effect of C10 through direct host-guest encapsulation.NMR and isothermal titration calorimetry served to confirm the complexation between CP6A and C10 with robust affinity[(1.07±0.14)×10^(7)L/mol].The CP6A was further used as a reversal agent of C10,which facilitated to decrease C10 concentration in mice blood and excrete via urinary clearance,resulting in rapid recovery from muscle relaxation.These favorable outcomes might lead us to suggest that this supramolecular strategy could allow patients to regain lucidity much faster than spontaneous recovery from anesthesia. | Yao Chai Longming Chen Yahan Zhang Liang Zhao Zhao Meng Junyi Chen Chunju Li Qingbin Meng | 2022 | Chinese Chemical Letters2022，33，6： | 0 |
| 15 | Summer habitat selection and impacts of human disturbance on leopard cats(Prionailurus bengalensis)显示文摘Introduction:As a consequence of habitat loss and degradation,the leopard cat(Prionailurus bengalensis)in China has become endangered and in need of urgent protection.In situ conservation of leopard cats must be based on an understanding of their habitat selection patterns.We studied the summer habitat of leopard cats using line-transect surveys in the northern Taihang Mountain region surrounding Beijing,China.We compared used plots with non-used plots in elevation,tree canopy,and 20 other ecological variables,and used Vanderploeg��Scavia’s resource selection index(VSI)to analyze habitat preferences.Outcomes/others:Results show that tree canopy,tree height,tree density,and stump quantity of used plots were significantly lower than non-used plots in summer,and that leopard cats preferred habitats located on northern,flat slopes with lower slope,shrub-dominated,dry soil,and less fallen-wood.Leopard cats had a strong tendency to use habitats near human disturbance areas with moderate levels of disturbance intensity.Conclusion:The results suggest that future conservation efforts should emphasize:(1)strengthening the protection and management of forest fringe shrub habitats to improve summer habitat suitability,and(2)environmental education and animal protection campaigns to promote community biodiversity conservation. | Jiayi Wu Jing Wang Yinjiu Zhu Xiangli Bu Rongwei Xiang Qingbin Lu Shaopeng Cui Yinghong Hao Yan Sheng Xiuxiang Meng | 2020 | Ecosystem Health and Sustainability2020，6，1： | 0 |
| 16 | Coassembly of Macrocyclic Amphiphiles for Anti-β-Amyloid Therapy of Alzheimer’s Disease显示文摘Based on the amyloid hypothesis,anti-β-amyloid(Aβ)therapy has dominated clinical trials for the prevention and treatment of Alzheimer’s disease(AD)in recent years.A key element of this strategy is the interaction between therapeutic agents and Aβ.However,the design and development of artificial receptors that may render selective and strong recognition toward Aβremains a huge challenge because of the complexity and size of peptide guests and their flexible conformation. | Yu-Chen Pan Hui Wang Xinxin Xu Han-Wen Tian Hong Zhao Xin-Yue Hu Yu Zhao Yang Liu Guihua Ding Qingbin Meng Bart Jan Ravoo Tao Zhang Dong-Sheng Guo | 2021 | CCS Chemistry2021，3，9： | 0 |
| 17 | Editorial highlights显示文摘With the increasing scarcity of shallow resources,the mining depth of coal mines has gradually increased,and the safety problem has become increasingly prominent.The grouting technology for deep roadways in fractured rocks is one of key technologies for safe mining of deep resources.This paper by the team of Hongpu Kang,academician of the Chinese Academy of Engineering,systematically summarizes and analyzes the research findings in the theory,design,materials,processes,and equipment for the grouting reinforcement of fractured rocks surrounding the deep roadways.Several field cases in the Kouzidong coal mine are demonstrated on the application of pregrouting in front of heading faces,grouting in excavation,and postgrouting so as to evaluate the effects of these grouting reinforcements. | Qingbin Meng Heping Xie ChunFai Leung Xiaozhao Li Jianguo Wang | 2023 | Deep Underground Science and Engineering2023，2，1： | 0 |
| 18 | Supramolecular liquid barrier for sulfur mustard utilizing host-guest complexation of pillar[5]arene with triethylene oxide substituents显示文摘Sulfur mustard(SM) can be absorbed by skin quickly and cause serious system damage via reacting with nearly all cell constituents. Until now, there is still lack of effective antidotal therapy for SM and skin protection is highly important to defend SM. In this article, supramolecular liquid barrier based on pillar[5]arene with triethylene oxide substituents(EGP5) has been designed to impede the skin permeation of SM and further interaction with the skin tissue. EGP5 could encapsulate SM within its cavity, with a Kavalue of(5.10 ± 0.47) × 10^(2)L/mol. In vitro skin absorption test proved that EGP5 was capable to effectively prevent SM from penetrating through skin. This supramolecular liquid barrier was employed on rat models to systematically evaluate protective effect against SM intoxication. Pretreatment of EGP5could alleviate skin and system damage induced by SM and improve survival rate of poisoned rat models from 10% to 90%. Additionally, EGP5 served as protective materials could be highly reused after recycling several times. Overall, these findings have provided the first insight into the construction of convenient liquid material for SM protection. | Yahan Zhang Junyi Chen Longming Chen Liang Zhao Mengke Ma Xinbei Du Zhao Meng Han Zhang Zhibing Zheng Yongan Wang Chunju Li Qingbin Meng | 2023 | Chinese Chemical Letters2023，34，4： | 0 |
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