6篇
您的检索式：作者名="Qiu Shijing"
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| 1 | Comparison of simple discectomy and instrumented posterior lumbar interbody fusion for treatment of lumbar disc herniation combined with Modic endplate changes显示文摘 | Cao Peng Chen Zhe Zheng Yuehuan Wang Yuren Jiang Leisheng Yang Yaoqi Zhuang Chengyu Liang Yu Zheng Tao Gong Yaocheng Zhang Xingkai Wu Wenjian Qiu Shijing | 2014 | Chinese Medical Journal2014，，15： | 15 |
| 2 | Effect of body fat stores on total and regional bone mineral density in perimenopausal Chinese women显示文摘 | Zhifeng Yu Zhenan Zhu Tingting Tang Kerong Dai Shijing Qiu | 2009 | Journal of Bone and Mineral Metabolism2009，，3： | 1 |
| 3 | Relationships between osteocyte density and bone formation rate in human cancellous bone显示文摘 | Qiu Shijing Rao D Sudhaker Palnitkar S | 2002 | Bone2002，31，： | 1 |
| 4 | Electrorerduction of Co(Ⅱ) and La(Ⅲ) in ureamelt显示文摘 | Yang Qiqin Qiu Kairong Pan Shijing | 1995 | Rare Metals1995，14，3： | 1 |
| 5 | High Jc Epitaxial Superconducting YBa_2Cu_3O_(7-x) Thin Films显示文摘Excellent epitaxial growth of supercon-ducting YBa2 Cu3 O7-x thin films have beenrealized on(100)SrTiO3 and(100)ZrO2substrates by a planar rf or DC-magnetronsputtering apparatus with UHV system.Thequality of growth and the epitaxial orientationof the film strongly depended on substratetemperature,the substrate orientation and ox-ygen partial pressure.The films exhibitedsuperconducting onset at 92K and zero resist-ance at 90K with critical current density | Chen Lanfeng Zhou Li Wang Chaoqun General Research Institute of Non-ferrous Metals.Beijing,China Li Lin Zhao Bairu Zhang Yinzi Qiu Xianggang Institute of Physics,Academia Sinica,Beijing.China Pang Shijing Beijing Laboratory of Vacuum Physics,China Kou Yuanheng Department of Physics.Peking University,Beijing,China | 1990 | Rare Metals1990，10，1： | 0 |
| 6 | Lipid-conjugated siRNA hitchhikes endogenous albumin for tumor immunotherapy显示文摘With the development of a small interfering RNA(siRNA)delivery strategy,increasing siRNA therapeutics for tumor treatment appeared in clinical trials and pre-clinical development.However,the test results of such therapeutics unveiled that efficient siRNA delivery to tumor tissues is still challenging.Albumin is considered an ideal carrier for delivering hydrophobic agents into tumor tissue because it is highly concentrated and long-circulating in blood and has propensity of tumor enrichment.Herein,we synthesized lipid conjugated siRNAs(LsiRNAs),which showed high affinity to albumin.Mechanistically,LsiRNAs non-covalently bind to the hydrophobic core of albumin through its octadecyl tails.The small size of albumin/LsiRNAs allows the complex to penetrate tumor tissue efficiently.Biodistribution test proved that albumin extremely prolonged circulation time and increased tumor retention of associated LsiRNAs.Notably,LsiRNA against programmed death ligand-1(Pdl1)efficiently suppressed tumor growth as well as prolonged survival time of tumor bearing mice by increasing infiltration of CD8^(+)T cells as well as promoted the maturation of dendritic cells both in tumor and lymph.Together,LsiRNAs provide a simple but effective way for siRNA tumor delivery that“hitchhikes”on albumin. | Bo Hu Sudong Kong Yuhua Weng Deyao Zhao Abid Hussain Qingze Jiao Shijing Zhan Ling Qiu Jianguo Lin Minhao Xie Bo Li Yuanyu Huang | 2023 | Chinese Chemical Letters2023，34，11： | 0 |
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