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    题名 作者 年代 出处 被引量
1A critical role of IFNγ in priming MSC-mediated suppression of T cell proliferation through up-regulation of BT-H1显示文摘Huiming Sheng 2008Cell Research2008,18,8:55
2Antigen-presenting effects of effector memory Vγ9Vδ2 T cells in rheumatoid arthritis显示文摘Chaoying Hu Liu Qian Yi Miao Qiuyu Huang Ping Miao Ping Wang Qiwen Yu Hong Nie Jiying Zhang Dongyi He Rong Xu Xuehua Chen Bingya Liu Dongqing Zhang 2012Cellular & Molecular Immunology2012,9,3:18
3I-IBV life cycle is restricted in mouse hepatocytes .~xpressing human NTCP显示文摘Hanjie Li Qiuyu Zhuang Yuze Wang Tianyi'ng Zhang Jinghua Zhao Yali Zhang Junfang Zhang Yi Lin Quan Yuan Ningshao Xia Jiahuai Han 2014Cellular & Molecular Immunology2014,11,2:14
4Effect of initial material bulk density and easily-degraded organic matter content on temperature changes during composting of cucumber stalk显示文摘To inactivate the potentially pathogenic microorganisms and safely utilize vegetable waste compost, ultra-high temperatures(> 70°C) should be maintained during the composting without having an inhibitory effect on maturity. This study investigated the influence of bulk density(part 1) and easily-degraded organic matter content(EDOMC, part 2) on temperature evolution during vegetable waste composting: Part 1: corn straw with different particle sizes was used to achieve different bulk densities in the composting material(BD1–BD3); Part 2: partial or total substitution of the corn straw by corn starch was carried out to obtain different EDOMC(ED1–ED4). The composting experiments were conducted in a labscale reactor(1.75 kg material) and lasted for 30 d. Temperature and CO2 emission were recorded daily, and the organic matter, lignocellulose, microbial activity, germination index(GI) and C/N of the samples were measured at different stages. The highest temperature(65.7°C) in part 1 occurred in the treatment with the bulk density of 0.35 g/cm3, which also had the longest thermophilic phase. Bulk density was found to seriously influence the utilization efficiency of O2 and heat transfer through materials, rather than heat production from organic matter degradation. In experiment part 2, the highest temperature was obtained with EDOMC of 45%(71.4°C). Therefore, adjusting the bulk density to 0.35 g/cm3 and the easily-degraded organic matter content of the initial material to 45% was the best combination for reaching temperatures above 70°C during composting, with no inhibitory effect on the maturity of the compost product.Ruixue Chang Qiuyue Guo Qing Chen Maria Pilar Bernal Qian Wang Yanming Li 2019Journal of Environmental Sciences2019,31,6:11
5Molecular simulation of oligomer inhibitors for calcite scale显示文摘Molecular simulation was performed to study the interaction between CaCO3 crystal and several oligomer inhibitors, by using the equilibrium morphology method to calculate the growth morphology of CaCO3 without inhibitors. The calculated morphology agreed well with SEM photographs. Then, a double-layer model was built to investigate the interaction between calcite crystal and oligomer inhibitors containing maleic anhydride (MA) and acrylic acid (AA). Interaction energy per gram of an oligomer inhibitor was introduced as a scale of inhibition efficiency of different monomers. The results indicated that, for calcite scale inhibition, acrylamide (AM) and vinyl phosphonic acid (VPA) were the most efficient monomers, while allylsulfonic acid (AS) was the poorest. Increasing proportion of AM in dimer inhibitor molecule would improve the inhibition efficiency of MA, though, for a trimer, such as MA-AA-AM, certain sequence of monomers in the inhibitor molecule was necessary besides higher proportion of AM.Qiuyu Zhang Hua Ren Wenwen Wang Junping Zhang Hepeng Zhang 2012Particuology2012,10,3:11
6Genome-wide Analysis of Transcriptional Variability in a Large Maize-Teosinte Population显示文摘基因表示规定在控制植物显型和改编起一个重要作用。这里,我们报导对通过 transcriptome 的基因表示变化的一个全面评价大 maize-teosinte 分析试验性的人口。染色体宽的印射识别了 25 ? 660 表示为 17 的量的特点 loci (eQTL )? 311 基因,捕获表示变化的一个崭新的范围。我们发现本地 eQTL 更经常被印射到邻近的基因,显示表示 piggybacking 的一个模式,它因而创造了共同调整的基因簇。在共同调整的基因簇以内的基因趋于有相关功能和分享的染色质修正。远 eQTL 与他们显著地在特定的功能的范畴充实的目标形成了 125 个重要远 eQTL 热点。由集成信息的不同来源,我们为许多新陈代谢的小径识别了通常认为的 trans- 管理者。我们证明 bHLH 抄写因素 R1 和 hexokinase HEX9 可能分别地为 flavonoid 生合成和 glycolysis 充当关键管理者。而且,我们证明驯服或改进显著地影响了全球基因表示,与选择指向的许多基因。特别兴趣,为生合成可能经历了的 benzoxazinoid 的 Bx 基因协调了在玉米和 teosinte 之间的 cis 规章的分叉,并且当玉米与一个不同草食动物社区传播了进适度的环境,使 Bx12 失去活性的 transposon 插入在强壮的选择下面。Xufeng Wang Qiuyue Chen Yaoyao Wu Zachary H. Lemmon Guanghui Xu Cheng Huang Yameng Liang Dingyi Xu Dan Li John F. Doebley Feng Tian 2018Molecular Plant2018,11,3:7
7Experimental Study on Aqueous Phase Entrainment in a Mixer-settler with Double Stirring Mode显示文摘The mixer-settler is a core device of solvent extraction for separating rare earth elements. There are some adverse effects like high rare earth accumulation and poor production efficiency during industrial production. Current researches usually focus on changing the structure of the mixer-settler without making a breakthrough towards gravity clarification. In this paper, in order to improve the efficiency of clarification, a mixer-settler with double stirring mode was designed and manufactured by adding a stirring device in the settler after reducing the volume of the settler. The innovation of this research involves adopting the ultraviolet-visible spectrophotometer to investigate the quantity of aqueous phase entrainment at the settler outlet in order to measure the clarification degree. Experimental results show that the clarification effect with stirring is better than that without stirring. The clarification effect is ameliorated as the stirring speed increases. Generally, the clarification effect shows a best condition when the offset distance is 12.5 cm, making the phase entrainment reduced to less than 0.1%. When the clearance over the tank bottom is 7 cm and 10 cm, respectively, the quantity of aqueous phase entrainment is better than the case with a clearance of 4 cm. The results show that the stirring paddle close to the mixed phase zone can better promote the two-phase separation.Wang Shuchan Zhang Tingan Zhao Qiuyue Liu Yan Wu Qiuyang 2013China Petroleum Processing & Petrochemical Technology2013,15,2:6
8HCCDB: A Database of Hepatocellular Carcinoma Expression Atlas显示文摘Hepatocellular carcinoma(HCC) is highly heterogeneous in nature and has been one of the most common cancer types worldwide. To ensure repeatability of identified gene expression patterns and comprehensively annotate the transcriptomes of HCC, we carefully curated 15 public HCC expression datasets that cover around 4000 clinical samples and developed the database HCCDB to serve as a one-stop online resource for exploring HCC gene expression with userfriendly interfaces. The global differential gene expression landscape of HCC was established by analyzing the consistently differentially expressed genes across multiple datasets. Moreover, a 4 D metric was proposed to fully characterize the expression pattern of each gene by integrating data from The Cancer Genome Atlas(TCGA) and Genotype-Tissue Expression(GTEx). To facilitate a comprehensive understanding of gene expression patterns in HCC, HCCDB also provides links to third-party databases on drug, proteomics, and literatures, and graphically displays the resultsfrom computational analyses, including differential expression analysis, tissue-specific and tumorspecific expression analysis, survival analysis, and co-expression analysis. HCCDB is freely accessible at http://gffzzbcb113a830484641hqqk65x09095060kc.ffgz.tsg.suse.edu.cn/database/hccdb.Qiuyu Lian Shicheng Wang Guchao Zhang Dongfang Wang Guijuan Luo Jing Tang Lei Chen Jin Gu 2018Genomics, Proteomics & Bioinformatics2018,16,4:5
9Emissions of parent, nitrated, and oxygenated polycyclic aromatic hydrocarbons from indoor corn straw burning in normal and controlled combustion conditions显示文摘Emission factors(EFs) of parent polycyclic aromatic hydrocarbons(pPAHs), nitrated PAHs(nPAHs), and oxygenated PAHs(oPAHs)were measured for indoor corn straw burned in a brick cooking stove under diferent burning conditions. The EFs of total 28 pPAHs,6 nPAHs and 4 oPAHs were(7.9 ± 3.4),(6.5 ± 1.6)×10 3, and(6.1 ± 1.4)×10 1mg/kg, respectively. Fuel charge size had insignificant influence on the pollutant emissions. Measured EFs increased significantly in a fast burning due to the oxygen deficient atmosphere formed in the stove chamber. In both restricted and enhanced air supply conditions, the EFs of pPAHs, nPAHs and oPAHs were significantly higher than those measured in normal burning conditions. Though EFs varied among diferent burning conditions, the composition profiles and calculated isomer ratios were similar, without significant diferences. The results from the stepwise regression model showed that fuel burning rate, air supply amount, and modified combustion efciency were the three most significant influencing factors, explaining 72%–85% of the total variations.Guofeng Shen Miao Xue Siye Wei Yuanchen Chen Bin Wang Rong Wang Yan Lv Huizhong Shen Wei Li Yanyan Zhang Ye Huang Han Chen Wen Wei Qiuyue Zhao Bing Li Haisuo Wu Shu Tao 2013Journal of Environmental Sciences2013,25,10:5
10Meta-Analysis:Prevalence of Food Allergy and Food Allergens—China, 2000−2021显示文摘What is already known about this topic?In recent decades,the prevalence of food allergy has increased worldwide;however,a comprehensive estimate of the prevalence of food allergy and allergens in China is not yet available.What is added by this report?By searching the English databases PubMed,Embase,Cochrane Library,and Chinese databases CNKI,Wanfang Data,and VIP Chinese epidemiological studies on food allergy,the probability of food allergy in China and related influencing factors were determined.What are the implications for public health practice?The findings of this study provide up-to-date estimates of the prevalence of food allergy rates in China in terms of age,gender,and the eight major food allergens.Jiangzuo Luo Qiuyu Zhang Yanjun Gu Junjuan Wang Guirong Liu Tao He Huilian Che 2022China CDC weekly2022,4,34:4
11Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis显示文摘Depression is a serious public-health issue.Recent reports have suggested higher susceptibility to viral infections in depressive patients.However,how depression affects antiviral innate immune signaling remains unknown.Here,we revealed a reduction in expression of Abelson helper integration site 1(AHI1)in the peripheral blood mononuclear cells(PBMCs)and macrophages from the patients with major depressive disorder(MDD),which leads to attenuated antiviral immune response.We found that depression-related arginine vasopressin(AVP)induces reduction of AHI1 in macrophages.Further studies demonstrated that AHI1 is a critical stabilizer of basal type-I-interferon(IFN-I)signaling.Mechanistically,AHI1 recruits OTUD1 to deubiquitinate and stabilize Tyk2,while AHI1 reduction downregulates Tyk2 and IFN-I signaling activity in macrophages from both MDD patients and depression model mice.Interestingly,we identified a clinical analgesic meptazinol that effectively stimulates AHI1 expression,thus enhancing IFN-I antiviral defense in depression model mice.Our study promotes the understanding of the signaling mechanisms of depression-mediated antiviral immune dysfunction,and reveals meptazinol as an enhancer of antiviral innate immunity in depressive patients.Hong-Guang Zhang Bin Wang Yong Yang Xuan Liu Junjie Wang Ning Xin Shifeng Li Ying Miao Qiuyu Wu Tingting Guo Yukang Yuan Yibo Zuo Xiangjie Chen Tengfei Ren Chunsheng Dong Jun Wang Hang Ruan Miao Sun Xingshun Xu Hui Zheng 2022Cell Research2022,32,10:3
12Influence of fuel mass load,oxygen supply and burning rate on emission factor and size distribution of carbonaceous particulate matter from indoor corn straw burning显示文摘The uncertainty in emission estimation is strongly associated with the variation in emission factor (EF),which could be influenced by a variety of factors such as fuel properties,stove type,fire management and even methods used in measurements.The impacts of these factors are complicated and often interact with each other.Controlled burning experiments were conducted to investigate the influences of fuel mass load,air supply and burning rate on the emissions and size distributions of carbonaceous particulate matter (PM) from indoor corn straw burning in a cooking stove.The results showed that the EFs of PM (EFPM),organic carbon (EFOC) and elemental carbon (EFEC) were independent of the fuel mass load.The differences among them under different burning rates or air supply amounts were also found to be insignificant (p > 0.05) in the tested circumstances.PM from the indoor corn straw burning was dominated by fine PM with diameter less than 2.1 μm,contributing 86.4%±3.9% of the total.The size distribution of PM was influenced by the burning rate and air supply conditions.On average,EF PM,EF OC and EF EC for corn straw burned in a residential cooking stove were (3.84±1.02),(0.846±0.895) and (0.391±0.350) g/kg,respectively.EF PM,EF OC and EF EC were found to be positively correlated with each other (p < 0.05),but they were not significantly correlated with the EF of co-emitted CO,suggesting that special attention should be paid to the use of CO as a surrogate for other incomplete combustion pollutants.Guofeng Shen Miao Xue Siye Wei Yuanchen Chen Bin Wang Rong Wang Huizhong Shen Wei Li Yanyan Zhang Ye Huang Han Chen Wen Wei Qiuyue Zhao Bin Li Haisuo Wu Shu Tao 2013Journal of Environmental Sciences2013,25,3:3
13Nationwide distribution of polycyclic aromatic hydrocarbons in soil of China and the association with bacterial community显示文摘Soil contamination by polycyclic aromatic hydrocarbons(PAHs)has raised great environmental concerns.However,the information on national wide distribution of PAHs in soil as well as their effect on soil bacterial community are limited.In this study,16 PAHs weremeasured in 94 soil samples collected across China.The total concentration of 16 PAHs(PAHs)in soil ranged from 74.0 to 17,657 ng/g(dry weight basis),with a median value of 200 ng/g.Pyrene was themajor soil PAH,with amedian concentration of 71.3 ng/g.Soil samples from Northeast China had a higher median concentration ofPAHs(1,961 ng/g)than those from other regions.Petroleum emission and wood/grass/coal combustion were potential sources for soil PAHs based on diagnostic ratios and positive matrix factors analysis.A nonnegligible ecological risk(hazard quotients>1)was found in over 20%of soil samples analyzed and the highestmedian total HQs value(8.53)was found in soils from Northeast China.The effect of PAHs on bacterial abundance,α-diversity,andβ-diversity was limited in the soils surveyed.Nevertheless,the relative abundance of some members in genera Gaiella,Nocardioides,and Clostridium was significantly correlated with the concentrations of some PAHs.Especially,the bacterium Gaiella Occulta showed potential in indicating soil contamination by PAH,which is worth further exploration.Qiuyue Zhang Meng Gao Xinhui Sun Yu Wang Chaolei Yuan Hongwen Sun 2023Journal of Environmental Sciences2023,,6:3
14Recent advances in electrospun electrode materials for sodium-ion batteries显示文摘Sodium-ion batteries(SIBs)have been considered as an ideal choice for the next generation large-scale energy storage applications owing to the rich sodium resources and the analogous working principle to that of lithium-ion batteries(LIBs).Nevertheless,the larger size and heavier mass of Na^(+)ion than those of Li^(+)ion often lead to sluggish reaction kinetics and inferior cycling life in SIBs compared to the LIB counterparts.The pursuit of promising electrode materials that can accommodate the rapid and stable Na-ion insertion/extraction is the key to promoting the development of SIBs toward a commercial prosperity.One-dimensional(1 D)nanomaterials demonstrate great prospects in boosting the rate and cycling performances because of their large active surface areas,high endurance for deformation stress,short ions diffusion channels,and oriented electrons transfer paths.Electrospinning,as a versatile synthetic technology,features the advantages of controllable preparation,easy operation,and mass production,has been widely applied to fabricate the 1 D nanostructured electrode materials for SIBs.In this review,we comprehensively summarize the recent advances in the sodium-storage cathode and anode materials prepared by electrospinning,discuss the effects of modulating the spinning parameters on the materials’micro/nano-structures,and elucidate the structure-performance correlations of the tailored electrodes.Finally,the future directions to harvest more breakthroughs in electrospun Na-storage materials are pointed out.Yao Wang Yukun Liu Yongchang Liu Qiuyu Shen Chengcheng Chen Fangyuan Qiu Ping Li Lifang Jiao Xuanhui Qu 2021Journal of Energy Chemistry2021,30,3:3
15Glossy15 Plays an Important Role in the Divergence of the Vegetative Transition between Maize and Its Progenitor, Teosinte显示文摘Dingyi Xu Xufeng Wang Cheng Huang Guanghui Xu Yameng Liang Qiuyue Chen Chenglong Wang Dan Li Jinge Tian Lishuan Wu Yaoyao Wu Li Guo Xuehan Wang Weihao Wu Weiqiang Zhang Xiaohong Yang Feng Tian 2017Molecular Plant2017,10,12:3
16GC-MS Analysis of Chemical Components of Volatile Oil in Different Parts of Fennel( Foenicuzu vulgare Mill. )显示文摘[Objectives] This study was conducted to analyze the composition of volatile oil in different parts of fennel(Foenicuzu vulgare Mill.) and to compare the differences in the composition of volatile oil in different parts of fennel.[Methods]The steam distillation method was applied to extract volatile oil from different parts of fennel,and the components of volatile oil from different parts of fennel were separated and identified by GC-MS.The relative content of each component was determined by the peak area normalization method.[Results]37,33,18,and 44 chemical components were separated from the volatile oil of fennel roots,stems,young leaves and fruit,respectively,accounting for 98.64%,99.34%,99.59% and 95.99% of the total volatile oil of corresponding parts.A total of 77 chemical components were identified in the four parts,of which 5 were common components.The main component of the volatile oil in the stems and young leaves was trans-anethole.The main components of the volatile oil in fruit were estragole and trans-anethole.And the main component of the volatile oil in the roots was dill apiol.The components in the volatile oil of fennel roots,stems,young leaves and fruit were different in type and content.[Conclusions]This study provides a theoretical reference for the further effective development and utilization of fennel resources.Wei CHEN Kaibin LI Lina LONG Wen YANG Jianghai WANG Qiuyue KONG Fujun SUN 2020Agricultural Biotechnology2020,9,2:3
17Progress on major genes for high fecundity in ewes显示文摘The existence of major genes affecting fecundity in sheep flocks throughout the world has been demonstrated.Three major genes whose mutations can increase ovulation rate have been discovered,and all related to the transforming growth factorβ(TGF-β)superfamily.The mutant FecB of bone morphogenetic protein receptor 1B(BMPR1B)has an additive effect on ovulation rate.Six mutations(Fec^(XI),Fec^(XH),Fec^(XG),Fec^(XB),Fec^(XL),Fec^(XR))of bone morphogenetic protein 15(BMP15)related with fertility have been identified that share the same mechanism.All the mutants can increase ovulation rate in heterozygotes and cause complete sterility in homozygotes.Homozygous ewes with two new mutations(FecX^(Gr),FecX^(O))of BMP15 had increased ovulation rate without causing sterility.There are five mutations in growth differentiation factor 9(GDF9)associated with sheep prolificacy where FecG^(E) and FecG^(F) have additive an effect on ovulation rate and litter size.The newly identifiedβ-1,4-N-acetylgalactosaminyltransferase 2(B4GALNT2)gene of FecL is proposed as a new mechanism of ovulation rate regulation in sheep.Woodlands is an X-linked maternally imprinted gene which increases ovulation rate.In addition,several putative major genes need to be verified.This review is focused on the identification of the mutations and mechanisms whereby the major genes affecting ovulation rate.Qiuyue LIU Zhangyuan PAN Xiangyu WANG Wenping HU Ran DI Yaxing YAO Mingxing CHU 2014Frontiers of Agricultural Science and Engineering2014,1,4:3
18Survivin Antisense Oligodeoxy-Nucleotid Induces Apoptosis in Leukaemia Cell Line K562显示文摘OBJECTIVE To investigate the effects of survivin antisense oligodeoxy-nucleotid (ASODN) on proliferation and apoptosis in the chronic myeloid leukemia cell line K562. METHODS Different concentrations of an antisense oligodeoxy-nucleotid and control sequence (scrambled ODN) targeting the survivin gene were transferred into K562 by a lipofectin reagent. The MTT assay was used to measure the growth inhibitory rate, IC50, and to observe the cytotoxicity of survivin ASODN in the K562 cells. The morphologic changes in the nucleus and the apoptotic rate were observed by Hoechst33342/PI staining. Caspase-3 activity was evaluated by a kinase activity assay. The changes of survivin protein expression after transfection were detected by Western blots. RESULTS Eight hours after transfection, fluorescence in the K562 cells was well distributed. Treatment of the cells for 44 h with different concentrations of survivin ASODN produced a IC50 of 800 nmol/L. The growth inhibitory rate with 200, 400, 600 and 1000 nmol/L of survivin ASODN was 15.8±1.6%, 23.8±5.9%, 37.1±5.6% and 77.3±2.5% respectively. After 36 h of of survivin ASODN treatment, distinct morphologic changes characteristic of cell apoptosis such as karyopyknosis and conglomeration were observed by Hoechst33342/PI staining. Caspase-3 activity increased significantly after treatment of the cells with different concentrations of survivin ASODN(P<0.01)and following treatment with 800 nmol/L survivin ASODN, survivin expression decreased significantly. CONCLUSION Survivin ASODN exerts an anti-cancer effect by inducing apoptosis in K562 leukaemia cells. Up-regulated expression of caspase-3 may play a role in this process.Lijun Chen Qiuyue Jin Hong Xie Ruimin Wang Li Yao 2006Chinese Journal of Clinical Oncology2006,3,6:3
19Natural-ageing-enhanced precipitation near grain boundaries in high-strength aluminum alloy显示文摘Artificial ageing above 165℃directly after quenching induces the formation of^50 nm wide precipitatefree zone(PFZ)and^100 nm wide precipitate-sparse zone(PSZ)consisting of coarse precipitates with a gradient in size and density toward the grain center in a commercial Al-Zn-Mg-Cu alloy.With the grain size decreasing,the fraction of PFZ and PSZ in a grain becomes larger and could even occupy the entire volume of the grain.This undesirable microstructure near the grain boundary is mitigated substantially by natural pre-ageing,leading to an exceptional enhancement of the age hardening potential at elevated temperatures.Natural ageing could fundamentally alter the precipitation near grain boundary,and is a promising method to optimize the precipitation hardening in high strength aluminum alloys with unconventionally small grains.Peipei Ma Chunhui Liu Qiuyu Chen Qing Wang Lihua Zhan Jianjun Li 2020Journal of Materials Science & Technology2020,42,11:3
20Microstructure and Corrosion Resistance of Arc Additive Manufactured 316L Stainless Steel显示文摘The gas tungsten arc welding based additive manufacturing (GTAW-AM) was carried out by printing 316L austenitic stainless steel on carbon steel substrate with different arc currents (140,160,180 A).Microstructure and corrosion resistance of additive manufactured components were investigated.The results show that the microstructure of the GTAW-AM austenitic stainless steel is obviously changed by the arc current.With arc current increasing from 140 to 180 A,the austenite grains become coarse due to the effect of welding heat input.Meanwhile,the quantity of ferrites in the austenite matrix is decreased and the morphology transforms from lath to skeleton.Moreover,σ phases are finally formed under the arc currents of 180 A owing to high welding heat input.Therefore,as the microstructure transform into coarse-grained austenites,low-quantity ferrites and new-generated σ phases,the GTAW-AM austenitic stainless steel presents a significantly decrease in corrosion resistance.And the reduction of corrosion resistance is mainly due to the formation of σ phase as a result from consuming the large amounts of Cr element from the matrix.杨可 WANG Qiuyu QU Yang JIANG Yongfeng BAO Yefeng 2020Journal of Wuhan University of Technology(Materials Science)2020,35,5:2
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