|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 高龄对男性生育力的影响显示文摘在过去的几十年里,现代社会的压力和期望使得育龄夫妇生育年龄总体推迟。已知女性在临近40岁时卵母细胞的产生将会明显减少,而高龄对男性精子生成能力的影响还知之甚少。男性生育年龄无明确限制,因而高龄对男性生育能力的影响还不完全清楚。本文将就目前已知的高龄对男性精子质量、生育能力和子代健康的影响进行综述,希望能在医生就男性推迟生育及高龄相关的风险咨询时起到一定的指导作用。 | Jason R Kovac Josephine Addai Ryan P Smith Robert M Coward Dolores J Lamb Larry I Lipshultz | 2013 | Asian Journal of Andrology2013，15，6： | 12 |
| 2 | Advances in hepatocellular carcinoma: Nonalcoholic steatohepatitis-related hepatocellular carcinoma显示文摘An increase in the prevalence of obesity and diabetes mellitus has been associated with the rise in non-alcoholic fatty liver disease(NAFLD). Two-thirds of the obese and diabetic populations are estimated to develop NAFLD. Currently, NAFLD is the most common etiology for chronic liver disease globally. The clinical spectrum of NAFLD ranges from simple steatosis, an accumulation of fat greater than 5% of liver weight, to nonalcoholic steatohepatitis(NASH), a more aggressive form with necroinflammation and fibrosis. Among the patients who develop NASH, up to 20% may advance to cirrhosis and are at risk for complications of end-stage liver disease. One of the major complications observed in patients with NASH-related cirrhosis is hepatocellular carcinoma(HCC), which has emerged as the sixth most common cancer and second leading etiology of cancer-related deaths worldwide. The incidence of HCC in the United States alone has tripled over the last three decades. In addition, emerging data are suggesting that a small proportion of patients with NAFLD may be at higher risk for HCC in the absence of cirrhosis - implicating obesity and diabetes mellitus as potential risk factors for HCC. | Fauzia Z Khan Ryan B Perumpail Robert J Wong Aijaz Ahmed | 2015 | World Journal of Hepatology2015，7，18： | 10 |
| 3 | Pathogenesis of hepatocarcinogenesis in non-cirrhotic nonalcoholic fatty liver disease:Potential mechanistic pathways显示文摘Although hepatocellular carcinoma(HCC) primarily arises in the background of liver cirrhosis,the development of HCC in nonalcoholic fatty liver disease(NAFLD) without cirrhosis is increasingly recognized. The pathogenesis of NAFLD associated non-cirrhotic HCC is distinct from that of cirrhotic HCC because the metabolic syndrome(MS) along with obesity and insulin resistance(IR) underlie several unique mechanisms that promote tumorigenesis. IR associated with MS,NAFLD,and type 2 diabetes mellitus lead to the release of multiple pro-inflammatory cytokines,including tumor necrosis factor alpha,interleukin-6,leptin and resistin,as well as decreased amounts of adiponectin. These processes favor the development of hepatic steatosis and inflammation within the liver,which precede HCC development. Nevertheless,further investigation is necessary to elucidate the determinants for development of HCC in patients with NAFLD in the absence of cirrhosis. | Ryan B Perumpail Andy Liu Robert J Wong Aijaz Ahmed Stephen A Harrison | 2015 | World Journal of Hepatology2015，7，22： | 6 |
| 4 | Risk factors for post-ERCP pancreatitis: A prospective, multicenter study显示文摘 | Martin L. Freeman James A. DiSario Douglas B. Nelson M.Brian Fennerty John G. Lee David J. Bjorkman Carol S. Overby Johannes Aas Michael E. Ryan Gary S. Bochna Michael J. Shaw Harry W. Snady Robert V. Erickson Joseph P. Moore Joseph P. Roel | 2001 | Gastrointestinal Endoscopy2001，，4： | 5 |
| 5 | Advances in alcoholic liver disease:An update on alcoholic hepatitis显示文摘Alcoholic hepatitis is a pro-inflammatory chronic liver disease that is associated with high short-term morbidity and mortality(25%-35% in one month) in the setting of chronic alcohol use. Histopathology is notable for micro- and macrovesicular steatosis, acute inflammation with neutrophil infiltration, hepatocellular necrosis, perivenular and perisinusoidal fibrosis, and Mallory hyaline bodies found in ballooned hepatocytes. Other findings include the characteristic eosinophilic fibrillar material(Mallory's hyaline bodies) found in ballooned hepatocytes. The presence of focal intense lobular infiltration of neutrophils is what typically distinguishes alcoholic hepatitis from other forms of hepatitis, in which the inflammatory infiltrate is primarily composed of mononuclear cells. Management consists of a multidisciplinary approach including alcohol cessation, fluid and electrolyte correction, treatment of alcohol withdrawal, and pharmacological therapy based on the severity of the disease. Pharmacological treatment for severe alcoholic hepatitis, as defined by Maddrey's discriminant factor ≥ 32, consists of either prednisolone or pentoxifylline for a period of four weeks. The body of evidence for corticosteroids has been greater than pentoxifylline, although there are higher risks of complications. Recently head-to-head trials between corticosteroids and pentoxifylline have been performed, which again suggests that corticosteroids should strongly be considered over pentoxifylline. | Randy Liang Andy Liu Ryan B Perumpail Robert J Wong Aijaz Ahmed | 2015 | World Journal of Gastroenterology2015，21，42： | 5 |
| 6 | An improved understanding of soil Cd risk to humans and low cost methods to phytoextract Cd from contaminated soils to prevent soil Cd risks显示文摘 | Rufus L. Chaney Philip G. Reeves James A. Ryan Robert W. Simmons Ross M. Welch J. Scott Angle | 2004 | BioMetals2004，，5： | 4 |
| 7 | Nonalcoholic Steatohepatitis is the Second Leading Etiology of Liver Disease Among Adults Awaiting Liver Transplantation in the U.S.显示文摘 | Robert J. Wong Maria Aguilar Ramsey Cheung Ryan B. Perumpail Stephen A. Harrison Zobair M. Younossi Aijaz Ahmed | 2014 | Gastroenterology2014，，： | 3 |
| 8 | The Cost-Effectiveness of Neoadjuvant Chemoradiation is Superior to a Surgery-First Approach in the Treatment of Pancreatic Head Adenocarcinoma显示文摘 | Daniel E. Abbott Ching-Wei David Tzeng Ryan P. Merkow Scott B. Cantor George J. Chang Matthew Harold Katz David J. Bentrem Karl Y. Bilimoria Christopher H. Crane Gauri R. Varadhachary James L. Abbruzzese Robert A. Wolff Jeffrey E. Lee Douglas B. Evans Jas | 2013 | Annals of Surgical Oncology2013，，3： | 3 |
| 9 | Advances in cirrhosis: Optimizing the management of hepatic encephalopathy显示文摘Hepatic encephalopathy(HE) is a major complication of cirrhosis resulting in significant socioeconomic burden, morbidity, and mortality. HE can be further subdivided into covert HE(CHE) and overt HE(OHE). CHE is a subclinical, less severe manifestation of HE and requires psychometric testing for diagnosis. Due to the time consuming screening process and lack of standardized diagnostic criteria, CHE is frequently underdiagnosed despite its recognized role as a precursor to OHE. Screening for CHE with the availability of the Stroop test has provided a pragmatic method to promptly diagnose CHE. Management of acute OHE involves institution of lactulose, the preferred first-line therapy. In addition, prompt recognition and treatment of precipitating factors is critical as it may result in complete resolution of acute episodes of OHE. Treatment goals include improvement of daily functioning, evaluation for liver transplantation, and prevention of OHE recurrence. For secondary prophylaxis, intolerance to indefinite lactulose therapy may lead to non-adherence and has been identified as a precipitating factor for recurrent OHE. Rifaximin is an effective add-on therapy to lactulose for treatment and prevention of recurrent OHE. Recent studies have demonstrated comparable efficacy of probiotic therapy to lactulose use in both primary prophylaxis and secondary prophylaxis. | Andy Liu Ryan B Perumpail Radhika Kumari Zobair M Younossi Robert J Wong Aijaz Ahmed | 2015 | World Journal of Hepatology2015，7，29： | 3 |
| 10 | Increased Quality of Life Among Hepatocellular Carcinoma Patients Treated with Radioembolization, Compared with Chemoembolization显示文摘 | Riad Salem Margaret Gilbertsen Zeeshan Butt Khairuddin Memon Michael Vouche Ryan Hickey Talia Baker Michael M. Abecassis Rohi Atassi Ahsun Riaz David Cella James L. Burns Daniel Ganger Al B. Benson Mary F. Mulcahy Laura Kulik Robert Lewandowski | 2013 | Clinical Gastroenterology and Hepatology2013，，： | 2 |
| 11 | 用文献计量数据解读中国和印度的科技发展显示文摘该文采用SCI/SSCI数据库,对通信联系人中至少含有一位印度/中国人的科技论文进行了文献计量学和计算语言学分析。依据对印度和中国科技文献单独分析的结果,深入地探讨了两国在科技领域的差异。借助不同的分析技术,包括影响因子分析、相关性图解以及文档聚类(传统聚类和模糊聚类),多角度地分析了中国和印度科技文献的基本学科结构体系(主要作者、研究单位等)与主要学科结构(学科重点以及学科重点之间的关系)。第一部分内容介绍了中国科技文献评估,第二部分阐述了印度科技文献评估,第三部分则为印度和中国科研成果的多角度比较。 | Ronald N. Kostoff Michael B. Briggs Robert L. Rushenberg Christine A. Bowles Sujit Bhattacharya Dustin Johnson Alan S. Icenhour Kimberly Nikodym Ryan B. Barth Simha Dodbele Michael Pecht 朱海峰 | 2007 | 科学观察2007，2，4： | 2 |
| 12 | Radiation Lobectomy: time-dependent analysis of future liver remnant volume in unresectable liver cancer as a bridge to resection显示文摘 | Michael Vouche Robert J. Lewandowski Rohi Atassi Khairuddin Memon Vanessa L. Gates Robert K. Ryu Ron C. Gaba Mary F. Mulcahy Talia Baker Kent Sato Ryan Hickey Daniel Ganger Ahsun Riaz Jonathan Fryer Juan Carlos Caicedo Michael Abecassis Laura Kulik Riad S | 2013 | Journal of Hepatology2013，，： | 2 |
| 13 | Risk factors for post-ERCP pancreatitis: A prospective, multicenter study显示文摘 | Martin L. Freeman James A. DiSario Douglas B. Nelson M.Brian Fennerty John G. Lee David J. Bjorkman Carol S. Overby Johannes Aas Michael E. Ryan Gary S. Bochna Michael J. Shaw Harry W. Snady Robert V. Erickson Joseph P. Moore Joseph P. Roel | 2001 | Gastrointestinal Endoscopy2001，，4： | 2 |
| 14 | Bridging Sexual Boundaries: Men Who Have Sex with Men and Women in a Street-Based Sample in Los Angeles显示文摘 | Pamina M. Gorbach Ryan Murphy Robert E. Weiss Christopher Hucks-Ortiz Steven Shoptaw | 2009 | Journal of Urban Health2009，，1： | 1 |
| 15 | IKONOS Spatial Resolution and Image interpretability Characterization 显示文摘 | RYAN Robert | 2003 | Remote Sensing of Environment2003，88，： | 1 |
| 16 | Pre-holiday Effect:International Evidence on the Decline and Reversal ofa Stock Market Anomaly显示文摘 | Ryan Chong Robert Hudson | 2005 | Journal of Money and Finance2005，，24： | 1 |
| 17 | Influence of social capital on community pre- paredness for wildfires 显示文摘 | Menka Bihari Robert Ryan | 2012 | Landscape and Urban Planning2012，106，3： | 1 |
| 18 | Expanded use of aggressive therapies improves survival in early and intermediate hepatocellular carcinoma显示文摘 | Edith Y. Ho Myrna L. Cozen Hui Shen Robert Lerrigo Erica Trimble James C. Ryan Carlos U. Corvera Alexander Monto | 2014 | HPB2014，，8： | 1 |
| 19 | Nest construction by a ground-nesting bird represents a potential trade-off between egg crypticity and thermoregulation显示文摘 | Paul M. Mayer Levica M. Smith Robert G. Ford Dustin C. Watterson Marshall D. McCutchen Mark R. Ryan | 2009 | Oecologia2009，，4： | 1 |
| 20 | Preserning rural character in New England:local resident' perceptions of alternative residential development显示文摘 | Robert L Ryan | 2002 | Landscape and Urban Planning2002，61，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员