|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 3 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 4 | Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial显示文摘 | Eric Lawitz Fred F Poordad Phillip S Pang Robert H Hyland Xiao Ding Hongmei Mo William T Symonds John G McHutchison Fernando E Membreno | 2013 | The Lancet2013，，： | 5 |
| 5 | Transcriptional Regulatory Networks in Saccharomyces Cerevisiae显示文摘 | Lee T I Rinaldi N J Robert F | 2002 | Science2002，298，： | 1 |
| 6 | Bacterial RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited condition 显示文摘 | Paolo C Dave W Robert J B Don C A Jay H Martin S Mark A Ganesh K Sara S Robert D Santiago N Stephanie B Mary F Jayaprakash T Santanu D Christopher B Michael H L Jacqueline E H | 2008 | Plant Physiology2008，147，2： | 1 |
| 7 | Image quality of sparse -aperture designs for remote sensing显示文摘 | Robert D F Theodore A T Jason R C | 2002 | Optical Engineering2002，41，8： | 1 |
| 8 | The Control of Single-Celled Cotton Fiber Elongation by Developmentally Reversible Gating of Plasmodesmata and Coordinated Expression of Sucrose and K Transporters and Expansin显示文摘 | RUAN Y L Danny J L Robert T F | 2001 | The Plant Cell2001，13，： | 1 |
| 9 | Transcriptional regulatory networks in Saccharomyces cerevisiae 显示文摘 | Lee T I Rinaldi N J Robert F | 2002 | Science2002，298，： | 1 |
| 10 | Henoch-Schonlein purpura: a review article 显示文摘 | ROBERTS P F WALLER T A BRINKER T M | 2007 | South Med J2007，100，8： | 1 |
| 11 | Techniques for the study and development of microbial fuel cells: an electrochemical perspective 显示文摘 | Zhao F Robert C T S John R V | 2009 | Chem Soc Rev2009，38，： | 1 |
| 12 | Transcriptional regulatory networks in Saccharomyces cerevisiae 显示文摘 | Lee T I Rinaldi N J Robert F | 2002 | Science2002，298，5594： | 1 |
| 13 | Nutritional support for head- injured patients 显示文摘 | Yanagawa T Bunn F Roberts I | 2002 | Cochrane Database Syst Rew2002，，00： | 1 |
| 14 | Dynamic pattern formation in a vesicle-generating microfluidic device 显示文摘 | Thorsen T Roberts R W Arnold F H | 2001 | Phys Rev Lett2001，86，18： | 1 |
| 15 | Apathy and impaired emotional facial recognition networks overlap in Parkinson's disease: a PET study with conjunction analyses 显示文摘 | Robert G Le Jeune F Dondaine T | 2014 | J Neurol Neurosurg Psychiatry2014，85，10： | 1 |
| 16 | Transcriptional regulatory networks in saccharomyces cerevisiae 显示文摘 | Lee T I Rinaldi N J Robert F | 2002 | Science2002，298，： | 1 |
| 17 | Acetylation: a novel link be- tween double-strand break repair and autophagy 显示文摘 | Shubassi G Robert T Vanoli F | 2012 | Cancer Res2012，72，6： | 1 |
| 18 | Special issue correspon- dence doubly resonant cymbal-type transducers 显示文摘 | JAMES F T ROBERT E N | 1997 | IEEE Trans Ultrason Ferro Elect Freq Contr1997，44，5： | 1 |
| 19 | Crystallization-damage by sodium sulfate 显示文摘 | NICHOLAS T ROBERT J F GEORGEW S | 2003 | Journal of CulturalHeritage2003，，4： | 1 |
| 20 | Transcriptional regulatory net- works in saecharomyces cerevisia显示文摘 | Lee T I Rinaldi N J Robert F | 2002 | Science2002，298，5594： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员