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| 1 | Neoadjuvant sorafenib combined with gemcitabine plus oxaliplatin in advanced hepatocellular carcinoma显示文摘This paper reports the first case of a patient with hepatocellular carcinoma with lymph node metastasis treated by sorafenib combined with gemcitabine plus oxaliplatin,with a partial response and normalization of α fetoprotein,which allowed curative surgery.The potential synergy between these three drugs needs to be confirmed,and is currently being investigated in a randomized phase Ⅱ trial. | Nicolas Williet Olivier Dubreuil Tarek Boussaha Isabelle Trouilloud Bruno Landi Martin Housset Muriel Botti Philippe Rougier Jacques Belghiti Julien Taieb | 2011 | World Journal of Gastroenterology2011，17，17： | 8 |
| 2 | Effects of KRAS, BRAF, NRAS , and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis显示文摘 | Wendy De Roock Bart Claes David Bernasconi Jef De Schutter Bart Biesmans George Fountzilas Konstantine T Kalogeras Vassiliki Kotoula Demetris Papamichael Pierre Laurent-Puig Frédérique Penault-Llorca Philippe Rougier Bruno Vincenzi Daniele Santini Giusepp | 2010 | Lancet Oncology2010，，8： | 6 |
| 3 | Electrochemical ageing study of mixed lanthanum/praseodymium nickelates La2-xPrxNiO4+δ as oxygen electrodes for solid oxide fuel or electrolysis cells显示文摘The chemical and electrochemical stability of lanthanide nickelates La2 NiO4+δ(LNO),Pr2 NiO4+δ(PNO)and their mixed compounds La(2-x)PrxNiO4+δ(LPNOs)with x=0.5,1 or 1.5 is reported.The aim is to promote these materials as efficient electrodes for solid oxide fuel cell(SOFC)and/or solid oxide electrolysis cell(SOEC).La2 NiO4+δand La1.5Pr0.5NiO4+δcompounds are chemically very stable as powders over one month in the temperature range 600-800℃,while the other materials rich in praseodymium progressively decompose into various perovskite-deriving components with additional Pr6 O11.Despite their uneven properties,all these materials are quite efficient and sustainable as electrodes on top of gadolinium doped ceria(GDCBL)//yttrium doped zirconia(8 YSZ)electrolyte,for one month at 700℃without polarization.Under polarization(300 mA·cm-2),the electrochemical performances of LNO,PNO and La1.5Pr0.5NiO4+δ(LP5 NO)quickly degrade in SOFC mode,i.e.for the oxygen reduction reaction,while they show durability in SOEC mode,i.e.for the oxide oxidation reaction. | Vaibhav Vibhu Aurélien Flura Aline Rougier Clément Nicollet Sébastien Fourcade Teresa Hungria Jean-Claude Grenier Jean-Marc Bassat | 2020 | Journal of Energy Chemistry2020，29，7： | 6 |
| 4 | Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: Pooled analysis of the CRYSTAL and OPUS randomised clinical trials显示文摘 | Carsten Bokemeyer Eric Van Cutsem Philippe Rougier Fortunato Ciardiello Steffen Heeger Michael Schlichting Ilhan Celik Claus-Henning K?hne | 2012 | European Journal of Cancer2012，，10： | 5 |
| 5 | 中温固体氧化物燃料电池阴极材料LaBiMn_2O_6的制备与性能显示文摘采用固相法合成了中温固体氧化物燃料电池(IT-SOFCs)阴极材料La Bi Mn2O6,并利用X射线衍射(XRD)和电化学阻抗谱(EIS)进行表征。结果表明该材料与电解质Ce0.7Bi0.3O1.85(CBO)在1 000℃烧结12 h不发生反应。交流阻抗和直流极化测试结果发现,阴极极化电阻随测试温度的增加而逐渐减小,700℃空气中的极化电阻为0.71Ω·cm2;氧分压测试结果显示,在600~700℃范围内,电极反应的速率控制步骤为电极上发生的电荷转移反应。电极过电位为85 m V时,700℃的阴极电流密度达到216 m A·cm-2,表明La Bi Mn2O6是一种潜在的中温固体氧化物燃料电池(IT-SOFCs)阴极材料。 | 肖辉 孙丽萍 赵辉 霍丽华 Jean-Marc Bassat Aline Rougier Sébastien Fourcade Jean-Claude Grenier | 2015 | 无机化学学报2015，31，6： | 5 |
| 6 | Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial显示文摘 | Hansjochen Wilke Kei Muro Eric Van Cutsem Sang-Cheul Oh Gy?rgy Bodoky Yasuhiro Shimada Shuichi Hironaka Naotoshi Sugimoto Oleg Lipatov Tae-You Kim David Cunningham Philippe Rougier Yoshito Komatsu Jaffer Ajani Michael Emig Roberto Carlesi David Ferry Kuma | 2014 | Lancet Oncology2014，，11： | 4 |
| 7 | Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial显示文摘 | JY Douillard D Cunningham AD Roth M Navarro RD James P Karasek P Jandik T Iveson J Carmichael M Alakl G Gruia L Awad P Rougier | 2000 | The Lancet2000，，9209： | 4 |
| 8 | Randomised, placebo-controlled, double-blind, parallel-group phase III study evaluating aflibercept in patients receiving first-line treatment with gemcitabine for metastatic pancreatic cancer显示文摘 | Philippe Rougier Hanno Riess Robert Manges Petr Karasek Yves Humblet Carlo Barone Armando Santoro Sylvie Assadourian Laurence Hatteville Philip A. Philip | 2013 | European Journal of Cancer2013，，12： | 4 |
| 9 | Disease-Free Survival as a Surrogate for Overall Survival in Adjuvant Trials of Gastric Cancer: A Meta-Analysis显示文摘 | Koji Oba Xavier Paoletti Steven Alberts Yung-Jue Bang Jacqueline Benedetti Harry Bleiberg Paul Catalano Florian Lordick Stefan Michiels Satoshi Morita Yasuo Ohashi Jean-pierre Pignon Philippe Rougier Mitsuru Sasako Junichi Sakamoto Daniel Sargent Kohei Sh | 2013 | JNCI Journal of the National Cancer Institute2013，，21： | 3 |
| 10 | Optical coherence tomography angiography at the acute phase of optic disc edema显示文摘Background:The differential diagnosis of optic disc edema at the acute phase can be challenging.OCT angiography(OCTA)is a new technology allowing the visualization of the peripapillary vascular network and optic disc capillaries.The peripapillary network alterations of glaucoma and chronic non-arteritic anterior ischemic optic neuropathy(NAION)were reported.However,no OCTA studies on acute optic disc edema from various causes.The aim of this project was to use OCTA to demonstrate the vascular changes the optic nerve head of various types of optic disc edema at the acute phase.Methods:In this retrospective study,patients with non-arteritic anterior ischemic optic neuropathy(NAION),papillitis or papilledema were recruited.Each patient was imaged using the AngioPlex^(TM)CIRRUS^(TM)HD-OCT device(model 5000,Carl Zeiss Meditec,Inc.,Dublin,USA)with a scanning area of 6×6 mm^(2) centered on the optic disc.A morphological analysis of the peripapillary network was performed.For some patients with unilateral optic disc edema,a quantitative analysis was performed using a swept-source OCT-A system(PLEX®Elite 9000,Carl Zeiss Meditec,Inc.,Dublin,USA).Vessel perfusion density and flux index of the peripapillary area were calculated.Results:Eight eyes with NAION(4 patients),12 eyes with papillitis(6 patients)and 25 eyes with papilledema(13 patients)were imaged.The apparent disappearance or moderate pattern alteration of the peripapillary capillary vessels were observed in patients with NAION or papillitis,respectively.For papilledema,the capillaries at the surface of the optic disc were dilated and tortuous,but no peripapillary network pattern changes were observed.The quantitative analysis did not show any difference of peripapillary network between NAION and healthy eyes.For papillitis,the flux index was higher in inflammatory eyes compared to the healthy eyes in average(p=0.03).Conclusion:At the acute phase,the morphological analysis of OCT-A appeared to be more useful than the quantification analysis,facilitating the differentiation between the three kinds of ONH edema:ischemic,inflammatory and papilledema. | Marie-Bénédicte Rougier Mélanie Le Goff Jean-François Korobelnik | 2018 | Eye and Vision2018，5，1： | 3 |
| 11 | Towards a pan-European consensus on the treatment of patients with colorectal liver metastases显示文摘 | Eric Van Cutsem Bernard Nordlinger Rene Adam Claus-Henning K?hne Carmelo Pozzo Graeme Poston Marc Ychou Philippe Rougier | 2006 | European Journal of Cancer2006，，14： | 2 |
| 12 | 钴掺杂Sr1.5La0.5MnO4的合成及高温电化学性能研究显示文摘采用EDTA-柠檬酸法合成了中温固体氧化物燃料电池阴极材料Sr_(1.5)La_(0.5)Mn_(1-x)Co_xO_4(SLMCOx),并利用粉末X射线衍射(XRD)、X射线光电子能谱(XPS)以及电化学交流阻抗谱(EIS)进行表征。结果表明,该材料与Ce0.9Gd0.1O1.95(CGO)在1 200℃烧结12 h不发生化学反应。随着Co掺入量的增加,氧化物中Mn^(3+)和Co^(2+)含量增多,晶格氧含量降低,晶格畸变率增大。交流阻抗谱(EIS)测试结果显示,钴的掺杂明显降低电极的极化电阻,其中Sr_(1.5)La_(0.5)Mn_(0.7)Co_(0.3)O_4阴极在700℃空气中的极化电阻为0.62Ω·cm^2,明显小于Sr_(1.5)La_(0.5)MnO_4阴极在750℃的极化电阻(1.5Ω·cm^2),表明钴掺杂的Sr_(1.5)La_(0.5)Mn_(1-x)CoxO_4是一种潜在的IT-SOFC阴极材料。 | 范宇航 孙丽萍 霍丽华 赵辉 Jean-Marc Bassat Aline Rougier Sebastien Fourcade Jean-Claude Grenier | 2016 | 无机化学学报2016，32，10： | 2 |
| 13 | Effective treatment of advanced biliary tract carcinoma using 5-fluorouracil continuous infusion with cisplatin显示文摘 | M. Ducreux P. Rougier A. Fandi M.-C. Clavero-Fabri A.-L. Villing F. Fassone L. Fandi J. Zarba J.-P. Armand | 1998 | Annals of Oncology1998，，6： | 2 |
| 14 | The Ratio of Metastatic to Examined Lymph Nodes Is a Powerful Independent Prognostic Factor in Rectal Cancer显示文摘 | Frédérique Peschaud Stéphane Benoist Catherine Julié Alain Beauchet Christophe Penna Philippe Rougier Bernard Nordlinger | 2008 | Annals of Surgery2008，，6： | 2 |
| 15 | 显示文摘 | Striebel K A Rougier A Horne C R | 1999 | Proc Electrochem Soc1999，16，： | 1 |
| 16 | 显示文摘 | Rougier A Gravereau P Delmas C | 1996 | J Electrochem Soc1996，143，4： | 1 |
| 17 | Phase Ⅱ study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy显示文摘 | Rougier P Bugat R Douillard JY | 1997 | J Clin Oncol1997，15，1： | 1 |
| 18 | Clinical efficacy of Oxaliplatin monotherapy:Phase Ⅱ trials in advanced colorectal cancer 显示文摘 | Becouarn Y Rougier P | 1998 | Semin Oncol1998，25，5： | 1 |
| 19 | Electrochemical performances of layered LiM1 yM'yO2 (M=Ni, Co; M'=Mg, Al, B) oxides in lithium batteries显示文摘 | Julien C Nazri G A Rougier A | 2000 | Solid State Ionics2000，135，14： | 1 |
| 20 | On the behavior of the LixNiO2 system:an electrochemical and structural overview显示文摘 | Delmas C Pérès J P Rougier A | 1997 | J Power Sources1997，68，1： | 1 |
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