|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treatment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trial显示文摘 | Kris V Kowdley Eric Lawitz Israel Crespo Tarek Hassanein Mitchell N Davis Michael DeMicco David E Bernstein Nezam Afdhal John M Vierling Stuart C Gordon Jane K Anderson Robert H Hyland Hadas Dvory-Sobol Di An Robert G Hindes Efsevia Albanis William T Symo | 2013 | The Lancet2013，，9883： | 3 |
| 2 | Human enamel thickness and ENAM polymorphism显示文摘The tooth enamel development gene, enamelin(ENAM), showed evidence of positive selection during a genome-wide scan of human and primate DNA for signs of adaptive evolution. The current study examined the hypothesis that a single-nucleotide polymorphism(SNP) C14625T(rs7671281) in the ENAM gene identified in the genome-wide scan is associated with a change in enamel phenotype. African Americans were selected as the target population, as they have been reported to have a target SNP frequency of approximately 50%, whereas non-Africans are predicted to have a 96% SNP frequency. Digital radiographs and DNA samples from 244 teeth in 133 subjects were analysed, and enamel thickness was assessed in relation to SNP status,controlling for age, sex, tooth number and crown length. Crown length was found to increase with molar number, and females were found to have thicker enamel. Teeth with larger crowns also had thicker enamel, and older subjects had thinner enamel.Linear regression and generalized estimating equations were used to investigate the relationship between enamel thickness of the mandibular molars and ENAM SNP status; enamel in subjects with the derived allele was significantly thinner(P = 0.040)when the results were controlled for sex, age, tooth number and crown length. The derived allele demonstrated a recessive effect on the phenotype. The data indicate that thinner dental enamel is associated with the derived ENAM genotype. This is the first direct evidence of a dental gene implicated in human adaptive evolution as having a phenotypic effect on an oral structure. | Diane M Daubert Joanna L Kelley Yuriy G Udod Carolina Habor Chris G Kleist Ilona K Furman Igor N Tikonov Willie J Swanson Frank A Roberts | 2016 | International Journal of Oral Science2016，8，2： | 2 |
| 3 | Disregulated glyceroneogenesis:PCK1 as a candidate diabetes and obesity gene显示文摘 | Elmus G B Robert E H Bénédicte A | 2004 | Trens in Endocrinology and Metabolism2004，15，3： | 1 |
| 4 | Comparisons andcontrasts of shale gas and tight gas developments, NorthAmerica experience and trends 显示文摘 | Robert L K William N K Daniel T G | 2012 | SPE 1608552012，，： | 1 |
| 5 | Activity optimization of pyridinyl N-oxide urea cytokinn mimics显示文摘 | Robert N Christine M G Wtlter H Y | 1988 | J Agri Food Chem1988，36，： | 1 |
| 6 | Transforming growth factor beta - receptor Ⅱ protein expression in benign prostatic hyper- plasia is associated with prostate volume and inflammation 显示文摘 | Descazeaud A Weinbreck N Robert G | | BJU Int0，108，22： | 1 |
| 7 | Levels of Expression of P-Selectin, E-Selectin, and Intercellular Adhesion Molecule-1 in Coronary Atherectomy Specimens from Patients With Stable and Unstable Angina Pectoris显示文摘 | Alan N Tenaglia MD Andrew J Buda MD Robert G Wilkins MD Michael K Barron MD Paul R Jeffords BS Khoa Vo BS Maureen O Jordan BS Barry A Kusnick MD David J Lefer PhD | 1997 | The American Journal of Cardiology1997，，6： | 1 |
| 8 | Compute and Storage Clouds Using Wide Area High performance Networks显示文摘 | Robert G L Gu Yuhong Sabala N | 2009 | Future Generation Computer Systems2009，25，2： | 1 |
| 9 | Hydraulic Performance of a Steep Single Layer Riprap Drainage Channel显示文摘 | ROBERT N E DONALD D G | 2008 | Journal of Hydraulic Engineering2008，134，11： | 1 |
| 10 | Polystyrene/decahydronaphthalene/propane phase equilibria and polymer conformation properties from intrinsic viscosities 显示文摘 | Cain N Hayavood A Roberts G | 2011 | Journal of Polymer Science Part B: Polymer Physics2011，49，15： | 1 |
| 11 | Influence ofvariability in motivation and affect on elite athlete burnout sus-ceptibility 显示文摘 | LEMYRE P N TREASURE D C ROBERTS G C | 2006 | J Sport Exe Psychol2006，28，： | 1 |
| 12 | Modeling the thermodynamic and transport properties of decahydronaphthalene/propane mixtures: Phase equilibria, density, and viscosity显示文摘 | Cain N Roberts G Kiserow D | 2011 | Fluid Phase Equilibria2011，305，1： | 1 |
| 13 | Astrocytes accumulate AI3 42 and give rise to astrocyte amyloid plaques in Alzheimer disease 显示文摘 | Robert G N Michael R D Andrea H L | 2003 | Brain Research2003，97，1： | 1 |
| 14 | Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation显示文摘 | Puissant A Robert G Fenouille N | | 0，，03： | 1 |
| 15 | Trau- matic lung injury treated by extracorporeal membrane oxygena- tion (ECMO) 显示文摘 | CORDELL-SMITH J A ROBERTS N PEEK G J | 2006 | Injury2006，37，1： | 1 |
| 16 | Standards in Isothermal Microcalorimetry 显示文摘 | Wadsoe I Robert N G | 2001 | Pure and Applied Chemistry2001，73，： | 1 |
| 17 | Influence of variability in motivation and affect on elite athlete burnout susceptibility显示文摘 | LEMYRE P N TREASURE D C ROBERTS G C | 2006 | J Sport Exe Psychol2006，28，1： | 1 |
| 18 | Alkaline treatment on commercially available aluminum rich mordenite显示文摘 | ADRI N C VAN L ROBERT W G SOPHIA L S | 2010 | Applied Catalysis A: General2010，382，： | 1 |
| 19 | Evaluation of an ELISA assay for rapid detection and quantification of neomycin phosphotransferaseⅡin transgenic plants显示文摘 | Roland J N John M M Robert G B | 1992 | Plant Molecular Biology Rep1992，10，： | 1 |
| 20 | Reactivity of heat treated coals in air at 500 ℃ 显示文摘 | ROBERT G J SATYENDRA P N PHILIP L W J | 1973 | Fuel1973，52，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员