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| 1 | Blood perfusion of the contralateral testis evaluated with contrast-enhanced ultrasound in rabbits with unilateral testicular torsion显示文摘The changes of blood perfusion of contralateral testis after unilateral testicular torsion remain controversial.In this study,28 New Zealand white male rabbits were randomly divided into five groups.Group A(n=8),the control group,underwent a sham operation on the unilateral testis without inducing testicular torsion.In groups B,C,and D(n=5 each),unilateral testicular torsion was induced,and,after 3,6 or 24 h,respectively,detorsion was performed.In group E(n=5),permanent unilateral testicular torsion was applied.Contrast-enhanced ultrasound was used to observe the blood perfusion of the contralateral testis at the following stages:pre-torsion(preopration),immediately post-torsion(postopration),pre-detorsion,immediately post-detorsion,and late-stage post-detorsion(6-12 h post-detorsion in groups B-D)or at a similar time point(15-21 h post-torsion in group E).Time-intensity curves were generated,and the following parameters were derived and analyzed:arrival time,time to peak intensity,peak intensity,and half-time of the descending peak intensity.The analysis revealed that blood perfusion of the contralateral testis increased immediately after testicular torsion on the opposite side(P<0.05),which increased with prolonged testicular torsion of the other testis.This research demonstrated that contrast-enhanced ultrasound was valuable in evaluating blood perfusion of the contralateral testis after unilateral testicular torsion. | Lin Chen Wei-Wei Zhan Zhou-Jun Shen Wen-Bin Rui Chen Lv Man Chen Jian-Qiao Zhou Ping Zhou Mi Zhou Ying Zhu | 2009 | Asian Journal of Andrology2009，11，2： | 10 |
| 2 | Transparent and flame retardant cellulose/aluminum hydroxide nanocomposite aerogels显示文摘Cellulose-based nanocomposite aerogels were prepared by incorporation of aluminum hydroxide(AH) nanoparticles into cellulose gels via in-situ sol-gel synthesis and following supercritical CO_2 drying. The structure and properties of cellulose/AH nanocomposite aerogels were investigated by Fourier transform infrared spectroscopy, scanning electron microscopy,ultraviolet-visible spectrometry, N_2 adsorption, thermogravimetric analysis, and micro-scale combustion calorimetry. The results indicated that the AH nanoparticles were homogeneously distributed within matrix, and the presence of AH nanoparticles did not affect the homogeneous nanoporous structure and morphology of regenerated cellulose aerogels prepared from1-allyl-3-methylimidazolium chloride solution. The resultant nanocomposite aerogels exhibited good transparency and excellent mechanical properties. Moreover, the incorporation of AH was found to significantly decrease the flammability of cellulose aerogels. Therefore, this work provides a facile method to prepare transparent and flame retardant cellulose-based nanocomposite aerogels, which may have great potential in the application of building materials. | Bin Yuan Jinming Zhang Jian Yu Rui Song Qinyong Mi Jiasong He Jun Zhang | 2016 | Science China Chemistry2016，59，10： | 4 |
| 3 | Differences in atheroma between Caucasian and Asian subjects with anterior stroke:A vessel wall MRI study显示文摘Background and purpose While extracranial carotid artery stenosis is more common among Caucasians and intracranial artery stenosis is more common among Asians,the differences in atherosclerotic plaque characteristics have not yet been extensively examined.We sought to investigate plaque location and characteristics within extracranial carotid and intracranial arteries in symptomatic Caucasians and Chinese using vessel wall MRI.Methods Subjects with recent anterior circulation ischaemic stroke were recruited and imaged at two sites in the USA and China using similar protocols.Both extracranial carotid and intracranial arteries were reviewed to determine plaque location and characteristics.Results The prevalence of extracranial carotid plaque in Caucasians and Chinese was 73.1%and 49.1%,respectively(p=0.055).Prevalence of intracranial plaque was 38.5%and 69.1%in Caucasians and Chinese,respectively(p=0.02).Furthermore,42% of Caucasians and 16%of Chinese had high-risk plaque(HRP)features(intraplaque haemorrhage,luminal surface disruption)in the extracranial carotid artery(p=0.03).The prevalence of HRP features in intracranial arteries was not significantly different between the two cohorts(4%vs 11%;p=0.42).Conclusions Differences in the location and characteristics of cerebrovascular atherosclerosis were identified by vessel wall MRI in US Caucasian and Chinese subjects with recent anterior circulation ischaemic stroke.Extracranial carotid plaques with HRP features were more common in Caucasians.Intracranial plaques were more common in Chinese subjects,but no significant difference between the two cohorts in intracranial HRP prevalence was found.Larger studies using vessel wall imaging to investigate racial differences in cerebrovascular disease may inform underlying mechanisms of HRP development and may ultimately help guide appropriate therapy. | Hiroko Watase Mi Shen Binbin Sui Peiyi Gao Dong Zhang Jie Sun Niranjan Balu Daniel S Hippe Gail P Jarvik Xihai Zhao Rui Li Shuo Chen Chun Yuan Thomas S Hatsukami | 2021 | Stroke & Vascular Neurology2021，6，1： | 4 |
| 4 | Abundant Production of Reactive Water Radical Cations under Ambient Conditions显示文摘Water radical cations,the crucial intermediates in many aqueous reactions and biochemical processes,are difficult to investigate experimentally due to their short lifetime andlowabundance.Herein,ahomemade device based on energy-tunable discharge was employed to deposit suitable amounts of energy to atmospheric pressure pure water vapor for abundant production of water radical cations,stabilized as(H_(2)O)n^(+·)(n=2-5)with a maximal abundance of≥8.3×10^(6) cps for(H_(2)O)_(2)^(+·),characterized by mass spectrometry(MS).The abundance of water radical cations was optimized by adjusting the experimental parameters such as the discharge voltage(2.5 kV),temperature of the MS inlet(140℃),carrier gas flow(20mL/min),and the distance between the discharge tip and MS inlet(12 mm).The ambient formation of water radical cationswas further confirmedby thehigh reactivity of as-prepared water radical cations,which reacted with benzene,ethyl acetate,and dimethyl disulfide instantly,showing rich chemistry with ionic and radical characteristics.Moreover,the computations usingCCSD(T)//MP2 method and density functional theory confirmed that the O-O single-electron bound dimer(B),as well as the hydronium hydroxyl radical complex(A),accounted for the unusual chemistry of the water radical cations,providing a facile approach to access the high reactivity ofwater radical cations under the ambient conditions. | Meng Wang Xiao-Fei Gao Rui Su Peng He Yuan-Yuan Cheng Ke Li Dongbo Mi Xiaoping Zhang Xinglei Zhang Huanwen Chen R.Graham Cooks | 2022 | CCS Chemistry2022，4，4： | 3 |
| 5 | Treated dentin matrix induces odontogenic differentiation of dental pulp stem cells via regulation of Wnt/β-catenin signaling显示文摘Treated dentin matrix(TDM)is an ideal scaffold material containing multiple extracellular matrix factors.The canonical Wnt signaling pathway is necessary for tooth regeneration.Thus,this study investigated whether the TDM can promote the odontogenic differentiation of human dental pulp stem cells(hDPSCs)and determined the potential role of Wnt/β-catenin signaling in this process.Different concentrations of TDM promoted the dental differentiation of the hDPSCs and meanwhile,the expression of GSK3βwas decreased.Of note,the expression of the Wnt/β-catenin pathway-related genes changed significantly in the context of TDM induction,as per RNA sequencing(RNA seq)data.In addition,the experiment showed that new dentin was visible in rat mandible cultured with TDM,and the thickness was significantly thicker than that of the control group.In addition,immunohistochemical staining showed lower GSK3βexpression in new dentin.Consistently,the GSK3βknockdown hDPSCs performed enhanced odotogenesis compared with the control groups.However,GSK3βoverexpressing could decrease odotogenesis of TDM-induced hDPSCs.These results were confirmed in immunodeficient mice and Wistar rats.These suggest that TDM promotes odontogenic differentiation of hDPSCs by directly targeting GSK3βand activating the canonical Wnt/β-catenin signaling pathway and provide a theoretical basis for tooth regeneration engineering. | Sirui Liu Jingjing Sun Shuai Yuan Yanyu Yang Yuping Gong Ying Wang Runying Guo Xue Zhang Yiming Liu Hongyan Mi Meiyue Wang Mengzhe Liu Rui Li | 2022 | Bioactive Materials2022，7，1： | 2 |
| 6 | Characterization of a broad-energy germanium detector for its use in CJPL显示文摘The broad-energy germanium(BEGe)detector,with the ability of background discrimination using pulse shape discrimination,is a competitive candidate for neutrinoless double beta decay(ovββ)experiments.In this paper,we report our measurements of key parameters for detector modeling in a commercial p-type BEGe detector.Point-like sources are used to investigate energy resolution and linearity of the detector.A cylindrical volume source is used for efficiency calibration.With an assembled device for source positioning and a collimated ^(133)Ba source,the detector is scanned to check its active volume.Using an^(241)Am point-like source,the dead layer thicknesses is measured at about 0.17 mm on the front and 1.18 mm on the side.The detector characterization is of importance for BEGe detectors to be used in the ovββ experiments at China JinPing underground Laboratory(CJPL). | Zhi Zeng Yu-Hao Mi Ming Zeng Hao Ma Qian Yue Jian-Ping Cheng Jun-Li Li Rui Qiu Hui Zhang | 2017 | Nuclear Science and Techniques2017，28，1： | 2 |
| 7 | Synthesis of monodispersed Fe3O4@C core/shell nanoparticles显示文摘We report a facile method to synthesize dispersed Fe_3O_4@C nanoparticles(NPs). Fe_3O_4 NPs were firstly prepared via the high temperature diol thermal decomposition method. Fe_3O_4@C NPs were fabricated using glucose as a carbon source by hydrothermal process. The obtained products were characterized by X-ray diffraction(XRD), transmission electron microscopy(TEM), vibrating sample magnetometer(VSM) and Raman spectra. The results indicate that the original shapes and magnetic property of Fe_3O_4 NPs can be well preserved. The magnetic particles are well dispersed in the carbon matrix. This strategy would provide an efficient approach for existing applications in Li-ion batteries and drug delivery. Meanwhile, it offers the raw materials to assemble future functional nanometer and micrometer superstructures. | Rui Liu Shu Mi Yuanyuan Li Cong Chen Yong Xie Qiang Chen Ziyu Chen | 2016 | Science China Chemistry2016，59，4： | 2 |
| 8 | Duplication and transcriptional divergence of three Kunitz protease inhibitor genes that modulate insect and pathogen defenses in tea plant(Camellia sinensis)显示文摘Kunitz protease inhibitors(KPIs)are ubiquitous in plants and act as crucial compounds in defense responses against insect attack and pathogen infection.However,the influence of gene duplication on the postdivergence of the CsKPI genes involved in biotic stresses in tea plant is not well known.Here,we identified three CsKPI genes from tea plant(Camellia sinensis)and characterized their expression and evolutionary patterns among plant species.We found that CsKPI1,CsKPI2,and CsKPI3 diverged from their common ancestor 72.94 million years ago(MYA),and the tandem duplication of CsKPI2 and CsKPI3 occurred 26.78 MYA.An in vitro protein assay showed that the three CsKPI proteins were functional and inhibited the production of p-nitroanilide(PNA)from an artificial substrate.The three CsKPI-GFP fusion proteins localized to the cytoplasm.We showed that salicylic acid(SA)and transcripts of CsKPI2 and CsKPI3 significantly accumulated after infection with Glomerella cingulata.The application of exogenous SA stimulated the high expression of both CsKPI2 and CsKPI3 by activating cis-elements within their promoters.Under Ectropis oblique attack,CsKPI1 expression and jasmonic acid(JA)levels were more abundant in both insect-damaged leaf tissues and undamaged neighboring leaves.The application of jasmonic acid methyl ester elicited high expression levels of CsKPI1,suggesting that CsKPI1 accumulation requires JA production in tea plant.The overall findings suggest that the transcriptional divergence of KPI genes after duplication led to the specialized role of CsKPI1 in the physiological response to insect stress;the functional conservation between CsKPI2 and CsKPI3 confers resistance to pathogen infection in tea plant. | Junyan Zhu Yaxian He Xiaomei Yan Lu Liu Rui Guo Xiaobo Xia Daojie Cheng Xiaozeng Mi Lidiia Samarina Shenrui Liu Enhua Xia Chaoling Wei | 2019 | Horticulture Research2019，6，1： | 2 |
| 9 | Curative effect observation on deformed auricle treated with EarWell Infant Ear Correction System with modular parents'nursing education显示文摘Objective:To investigate the efficacy and patient satisfaction of the EarWell Infant Ear Correction System combined with modular parents'nursing education's curative effect on deformed auricle.Methods:A total of 42 patients(29 boys and 13 girls;73 ears;age≤3 months)with auricle deformities who had received EarWell Infant Ear Correction System's treatment and modular parents'nursing education in Guangzhou Children and Women's Medical Center between April and October 2018.The modular parents'education program is standardized by EarWell system.Physician and patients'parents compared the severity of auricle deformity separately before and after the treatment by using the auricle deformities visual analogue scales(VAS)rating system.Patient satisfaction was evaluated by using global aesthetic improvement scale(GAIS).The data collected of auricle deformities VAS and GAIS satisfaction score were applied to measure the treatment's effectiveness.Results:All the 42 patients(73 external ears)completed the treatment with EarWell Infant Ear Correction System and modular parents'nursing education.The mean age at initiation of treatment was 37.87±19.44 days and the therapeutic time span was 47.21±17.36 days.At the end of treatment,the physician's and patients'guardians rating of the severity of auricle deformity were significantly improved separately compared to the initial rating(8.33±1.27 vs.6.51±0.84;P<0.005)(5.77±1.59 vs.8.19±2.38 P<0.05).During the treatment and parents'home nursing care period,the side effect and complications were minor like skin eczema and irrigation;there were no severe complications such as necrosis of the skin and cartilage.The patient tolerance for the treatment was acceptable with the adequate parents'nursing care.Most patients'guardians were satisfied with the treatment outcomes of EarWell Infant Ear Correction System with more engagement of nursing care,the GAIS's rating were increased from pretreatment stage's 26.19%to treatment completed stage's 90.48%,and the difference was statistically significant(P<0.05).Conclusions:In this study,we proved that EarWell Infant Ear Correction System with its unique parents'modular nursing care education,as a noninvasive treatment,reasonably improved auricle morphological malformation,and patients'guardians satisfaction with few complications,which is worthy of a wildly clinical promotion. | Wei Wei Ren-Zhong Luo Zhen-Yun Huang Rui Mi | 2020 | Frontiers of Nursing2020，7，2： | 2 |
| 10 | Stem cell therapy for the treatment ofparasitic infections: is it far away- 显示文摘 | Zhang Y Mi JY Rui YJ | 2014 | Parasitol Res2014，113，2： | 1 |
| 11 | Effect of midazolam on the proliferation of neural stem cells isolated from rat hippocampus显示文摘In many recent studies,the inhibitory transmitter gamma-aminobutyric acid has been shown to modulate the proliferation,differentiation and survival of neural stem cells.Most general anesthetics are partial or allosteric gamma-aminobutyric acid A receptor agonists,suggesting that general anesthetics could alter the behavior of neural stem cells.The neuroprotective efficacy of general anesthetics has been recognized for decades,but their effects on the proliferation of neural stem cells have received little attention.This study investigated the potential effect of midazolam,an extensively used general anesthetic and allosteric gamma-aminobutyric acid A receptor agonist,on the proliferation of neural stem cells in vitro and preliminarily explored the underlying mechanism.The proliferation of neural stem cells was tested using both Cell Counting Kit 8 and bromodeoxyuridine incorporation experiments.Cell distribution analysis was performed to describe changes in the cell cycle distribution in response to midazolam.Calcium imaging was employed to explore the molecular signaling pathways activated by midazolam.Midazolam(30-90 μM) decreased the proliferation of neural stem cells in vitro.Pretreatment with the gamma-aminobutyric acid A receptor antagonist bicuculline or Na-K-2Cl cotransport inhibitor furosemide partially rescued this inhibition.In addition,midazolam triggered a calcium influx into neural stem cells.The suppressive effect of midazolam on the proliferation of neural stem cells can be partly attributed to the activation of gamma-aminobutyric acid A receptor.The calcium influx triggered by midazolam may be a trigger factor leading to further downstream events. | Sanjun Zhao Yajing Zhu Rui Xue Yunfeng Li Hui Lu Weidong Mi | 2012 | Neural Regeneration Research2012，7，19： | 1 |
| 12 | Free great toe wrap-around flap combined with second toe medial flap for reconstruction of completely degloved fingers显示文摘 | Rui Y Mi J Shi H | 2010 | Microsurgery2010，30，6： | 1 |
| 13 | Cordyceps militaris polysaccharides can enhance the immunity and antioxidation activity in immunosuppressed mice显示文摘 | Mi Wang Xin Yu Meng Rui Le Yang Tao Qin Xiao Yang Wang Ke Yu Zhang Chen Zhong Fei Ying Li Yuan liang Hu Fei Qun Xue | 2012 | Carbohydrate Polymers2012，，2： | 1 |
| 14 | Simulated microgravity increases heavy ion radiation-induced apoptosis in human B lymphoblasts显示文摘 | Bingrong Dang Yuping Yang Erdong Zhang Wenjian Li Xiangquan Mi Yue Meng Siqi Yan Zhuanzi Wang Wei Wei Chunlin Shao Rui Xing Changjun Lin | 2013 | Life Sciences2013，，： | 1 |
| 15 | Free great toe wrap-around flap combined with second toe medial flap for reconstruction of completely degloved fingers显示文摘 | Rui Y Mi J Shi H Zhang Z | 2010 | Microsurgery2010，30，6： | 1 |
| 16 | Coating of α-MoO 3 on nitrogen-doped carbon nanotubes by electrodeposition as a high-performance cathode material for lithium-ion batteries显示文摘 | Hui Zhang Xiaojiang Liu Ruilin Wang Rui Mi Shaomin Li Yanhua Cui Yafeng Deng Jun Mei Hao Liu | 2015 | Journal of Power Sources2015，，： | 1 |
| 17 | Free great toe wrap-around com- bined with second toe medial flap for reconstruction of com- pletely degloved fingers显示文摘 | Rui Y Mi J Shi H | 2010 | Microsurgery2010，30，6： | 1 |
| 18 | Effects of nitrogen-doped carbon nanotubes on the discharge performance of Li-air batteries显示文摘 | Mi Rui Liu Hao Wang Hao | 2014 | Carbon2014，67，： | 1 |
| 19 | Ultrahigh accelerating gradient and quality factor of CEPC 650 MHz superconducting radio-frequency cavity显示文摘Two 650 MHz single-cell superconducting radio-frequency(SRF)cavities used for the Circular Electron Positron Collider(CEPC)were studied to achieve a high accelerating gradient(E_(acc))and high intrinsic quality factor(Q_(0)).The 650 MHz single-cell cavities were subjected to a combination of buffered chemical polishing(BCP)and electropolishing(EP),and their E_(acc) exceeded40 MV/m.Such a high E_(acc) may result from the cold EP with more uniform removal.BCP is easy,cheap,and rough,whereas EP is complicated,expensive,and precise Therefore,the combination of BCP and EP investigated in this study is suitable for surface treatments of mass SRF cavities.Medium temperature(mid-T)furnace baking was also conducted,which demonstrated an ultrahigh Q_(0) of 8×10^(10) at 22 MV/m for both cavities,and an extremely low BCS resistance(R_(BCS))of~1.0 nΩwas achieved a2.0 K. | Peng Sha Wei-Min Pan Song Jin Ji-Yuan Zhai Zheng-Hui Mi Bai-Qi Liu Chao Dong Fei-Si He Rui Ge Liang-Rui Sun Shi-Ao Zheng Ling-Xi Ye | 2022 | Nuclear Science and Techniques2022，33，10： | 1 |
| 20 | Free great toe wrap-around combined with second toe medial flap for reconstruction of completely degloved fingers显示文摘 | Rui Y Mi J Shi H | 2010 | Microsurgery2010，30，6： | 1 |
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