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| 1 | Tomography of the dynamic stress coefficient for stress wave prediction in sedimentary rock layer under the mining additional stress显示文摘In this study,the tomography of dynamic stress coefficient(TDSC)was established based on a mechanical model of stress wave propagation in bedding planes and a mathematical model of the stress wave attenuation in rock masses.The reliability of the TDSC was verified by a linear bedding plane model and field monitoring.Generally,the TDSC in the dynamic stress propagation of bedding planes increases with the following conditions:(1)the increase of the normal stiffness of the bedding plane,(2)the increase of the incident angle of the stress wave,(3)the decrease of the incident frequency of the stress wave,or(4)the growth of three ratios(the ratios of rock densities,elastic moduli,and the Poisson’s ratios)of rocks on either side of bedding planes.The additional stress weakens TDSC linearly and slowly during the stress wave propagation in bedding planes,and the weakening effect increases with the growth of the three ratios.Besides,the TDSC decreases exponentially in the rock mass as propagation distance increases.In a field case,the TDSC decreases significantly as vertical and horizontal distances increase and its wave range increases as vertical distance increases in the sedimentary rock layers. | Wenlong Shen Guocang Shi Yungang Wang Jianbiao Bai Ruifeng Zhang Xiangyu Wang | 2021 | International Journal of Mining Science and Technology2021，31，4： | 5 |
| 2 | Physical Layer Security for UAV Communications:A Comprehensive Survey显示文摘Due to its high mobility and flexible deployment,unmanned aerial vehicle(UAV)is drawing unprecedented interest in both military and civil applications to enable agile and ubiquitous connectivity.Mainly operating in an open environment,UAV communications benefit from dominant line-of-sight links;however,this on the other hand renders the communications more vulnerable to malicious attacks.Recently,physical layer security(PLS)has been introduced to UAV systems as an important complement to the conventional cryptography-based approaches.In this paper,a comprehensive survey on the current achievements of UAV-PLS is conducted.We first introduce the basic concepts including typical static/-mobile UAV deployment scenarios,the unique air-toground channel and aerial nodes distribution models,as well as various roles that a UAV may act when PLS is concerned.Then,we start by reviewing the secrecy performance analysis and enhancing techniques for statically deployed UAV systems,and extend the discussion to the more general scenario where the UAVs’mobility is further exploited.For both cases,respectively,we summarize the commonly adopted methodologies,then describe important works in the litera ture in detail.Finally,potential research directions and challenges are discussed to provide an outlook for future works in the area of UAV-PLS. | Jue Wang Xuanxuan Wang Ruifeng Gao Chengleyang Lei Wei Feng Ning Ge Shi Jin Tony Q.S.Quek | 2022 | China Communications2022，19，9： | 2 |
| 3 | Efficacy of intrapleural instillation of fibrinolytics for treating pleural empyema and parapneumonic effusion: a meta‐analysis of randomized control trials显示文摘 | Wencheng Nie Yanru Liu Jian Ye Liuhong Shi Fangchun Shao Kejing Ying Ruifeng Zhang | 2014 | The Clinical Respiratory Journal2014，，3： | 1 |
| 4 | Mining cotton fiber strength candidate genes based on transcriptome mapping显示文摘Cotton fiber strength is mainly determined during the secondary cell wall (SCW) thickening stage. In 24―25 days post anthesis (DPA) of SCW thickening stage, cDNA-amplified fragment length polymorphism (AFLP) was carried out to construct fiber transcriptome groups. Based on these groups, cotton fiber strength candidate genes were detected by composite interval mapping (CIM) through quantitative trait locus (QTL) scanning. The mapping population was the interspecific backcross BC1 of Gossypium hirsutum × G. barbadense. One hundred and fifteen BC1 plants were used for group construction with 102 qualified absence/presence polymorphic transcript-derived fragments (TDFs) from G. barbadense, and 78 TDFs were assigned into eight transcriptome groups that gave a total length of 462.63 centimorgans (cM). Two significant QTLs, FS1 and FS2, were detected and explained 16.08% and 15.87% of fiber strength variance, respectively. Of the six TDFs co-segregating with FS1 and FS2, except one encoding an unknown protein, five targeted putative phosphatidylinositol kinase, trehalose-6 phosphate synthase, MADS transcription factor, cellulose synthase-like protein and phenylalanine ammonia lyase, respectively. These functional genes were involved in plant cell wall morphogenesis or cellulose synthesis metabolism processes, and were considered as the candidate genes controlling cotton fiber strength. | LIU HengWei WANG XingFen PAN YuXin SHI RuiFeng ZHANG GuiYin MA ZhiYing | 2009 | Chinese Science Bulletin2009，54，24： | 1 |
| 5 | Construction of a genomic library of wild rice and Agrobacterium-mediated transformation of large insert DNA linked to BPH resistance locus显示文摘 | He Ruifeng Wang Yuanyuan Shi Zhenying | 2003 | Gene2003，321，： | 1 |
| 6 | Long noncoding RNA PVT1 promotes tumor growth and predicts poor prognosis in patients with diffuse large B-cell lymphoma显示文摘Dear Editor,Diffuse large B-cell lymphoma(DLBCL)is the most common and aggressive subtype of non-Hodgkin lymphoma(NHL),accounting for about 40%of all NHL cases[1].Lacking symptoms at early time and efficient therapeutic methods made DLBCL one of the most life-threatening types of hematopoietic malignancy[2,3].Therefore,identifying novel therapeutic biomarker for early detection and prognosis prediction is urgently needed. | Ruifeng Yang Tingting Shao Manmei Long Yongheng Shi Qiang Liu Linhua Yang Ming Zhan | 2020 | Cancer Communications2020，40，10： | 1 |
| 7 | Highly Ordered Mesoporous MoS2 with Expanded Spacing of the (002) Crystal Plane for Ultrafast Lithium Ion Storage显示文摘 | Hao Liu Dawei Su Ruifeng Zhou Bing Sun Guoxiu Wang Shi Zhang Qiao | 2012 | Adv. Energy Mater2012，，8： | 1 |
| 8 | Land use and land cover change and driving mechanism in the arid inland river basin: a case study of Tarim River, Xinjiang, China显示文摘 | Zhao Ruifeng Chen Yaning Shi Peiji | 2013 | Environmental Earth Sciences2013，68，2： | 1 |
| 9 | Large eddy simulation of city micro-atmospheric environment显示文摘Air quality is one of the important conditions for a better residence life in the populated urban area and it is closed related to the micro-atmospheric environment. Atmospheric environment is controlled by air motion with multi-scales in the city,while air flows in the residence area are of micro-scale atmospheric motion. This paper introduces a modern numerical simulation method,i.e. large eddy simulation(LES) ,for studying micro-atmospheric flows in the city residence area. For the complex flow features in the residence area,the proper application of LES is studied and various numerical methods are compared in order to investigate their effects on the prediction accuracy of micro-atmospheric flows,for instance,roughness elements and immersed boundary method for complex terrain,different subgrid models and so on. The wind field(including turbulence properties) and contaminant dispersion are computed by the proposed method for a model and a realistic residence area,and the numerical results are in good agreement with the experimental measurements. | CUI GuiXiang SHI RuiFeng WANG ZhiShi XU ChunXiao ZHANG ZhaoShun | 2008 | Science China(Physics,Mechanics & Astronomy)2008，51，8： | 1 |
| 10 | Combined endobronchial and endoscopic ultrasound-guided fine needle aspiration for mediastinal lymph node staging of lung cancer: A meta-analysis显示文摘 | Ruifeng Zhang Kejing Ying Liuhong Shi Lianfeng Zhang Lin Zhou | 2013 | European Journal of Cancer2013，，8： | 1 |
| 11 | Time-dependent deformation in high concrete-faced rockfill dam and separation between concrete face slab and cushion layer显示文摘 | ZHANG Bingyin WANG J G SHI Ruifeng | 2004 | Computers and Geotechnics2004，31，： | 1 |
| 12 | Construction of a genomic library of wild rice and Agrobactefium-mediated transforma- tion of large insert DNA linked to BPH resistance locus 显示文摘 | Ruifeng He Yuanyuan Wang Zhenying Shi | 2003 | Gene2003，321，： | 1 |
| 13 | Preparation and catalytic properties of RuSalen-functionalized periodic mesoporous silicas显示文摘 | Xiufeng Shi Binbin Fan Hongyu Li Ruifeng Li Weibin Fan | 2014 | Microporous and Mesoporous Materials2014，，： | 1 |
| 14 | Land use and land cover change and driving mechanism in the arid inland river basin : a case study of Tarim River, Xinjiang, China 显示文摘 | Zhao Ruifeng Chen Yaning Shi Peiji | 2013 | Environment Earth Sci- ence2013，68，2： | 1 |
| 15 | RNF126 Quenches RNF168 Function in the DNA Damage Response显示文摘DNA damage response(DDR) is essential for maintaining genome stability and protecting cells from tumorigenesis. Ubiquitin and ubiquitin-like modi?cations play an important role in DDR, from signaling DNA damage to mediating DNA repair. In this report, we found that the E3 ligase ring ?nger protein 126(RNF126) was recruited to UV laser micro-irradiation-induced stripes in a RNF8-dependent manner. RNF126 directly interacted with and ubiquitinated another E3 ligase, RNF168. Overexpression of wild type RNF126, but not catalytically-inactive mutant RNF126(CC229/232 AA), diminished ubiquitination of H2 A histone family member X(H2AX),and subsequent bleomycin-induced focus formation of total ubiquitin FK2, TP53-binding protein1(53 BP1), and receptor-associated protein 80(RAP80). Interestingly, both RNF126 overexpression and RNF126 downregulation compromised homologous recombination(HR)-mediated repair of DNA double-strand breaks(DSBs). Taken together, our ?ndings demonstrate that RNF126 negatively regulates RNF168 function in DDR and its appropriate cellular expression levels are essential for HR-mediated DSB repair. | Lianzhong Zhang Zhenzhen Wang Ruifeng Shi Xuefei Zhu Jiahui Zhou Bin Peng Xingzhi Xu | 2018 | Genomics, Proteomics & Bioinformatics2018，16，6： | 1 |
| 16 | Integrative Analysis of Genome,3D Genome,and Transcriptome Alterations of Clinical Lung Cancer Samples显示文摘Genomic studies of cancer cell alterations,such as mutations,copy number variations(CNVs),and translocations,greatly promote our understanding of the genesis and development of cancers.However,the 3D genome architecture of cancers remains less studied due to the complexity of cancer genomes and technical difficulties.To explore the 3D genome structure in clinical lung cancer,we performed Hi-C experiments using paired normal and tumor cells harvested from patients with lung cancer,combining with RNA sequenceing analysis.We demonstrated the feasibility of studying 3D genome of clinical lung cancer samples with a small number of cells(1×10^(4)),compared the genome architecture between clinical samples and cell lines of lung cancer,and identified conserved and changed spatial chromatin structures between normal and cancer samples.We also showed that Hi-C data can be used to infer CNVs and point mutations in cancer.By integrating those different types of cancer alterations,we showed significant associations between CNVs,3D genome,and gene expression.We propose that 3D genome mediates the effects of cancer genomic alterations on gene expression through altering regulatory chromatin structures.Our study highlights the importance of analyzing 3D genomes of clinical cancer samples in addition to cancer cell lines and provides an integrative genomic analysis pipeline for future larger-scale studies in lung cancer and other cancers. | Tingting Li Ruifeng Li Xuan Dong Lin Shi Miao Lin Ting Peng Pengze Wu Yuting Liu Xiaoting Li Xuheng He Xu Han Bin Kang Yinan Wang Zhiheng Liu Qing Chen Yue Shen Mingxiang Feng Xiangdong Wang Duojiao Wu Jian Wang Cheng Li | 2021 | Genomics, Proteomics & Bioinformatics2021，19，5： | 1 |
| 17 | KLF4 facilitates chromatin accessibility remodeling in porcine early embryos显示文摘Chromatin accessibility remodeling driven by pioneer factors is critical for the development of early embryos.Current studies have illustrated several pioneer factors as being important for agricultural animals,but what are the pioneer factors and how the pioneer factors remodel the chromatin accessibility in porcine early embryos is not clear.By employing low-input DNase-seq(liDNase-seq),we profiled the landscapes of chromatin accessibility in porcine early embryos and uncovered a unique chromatin accessibility reprogramming pattern during porcine preimplantation development.Our data revealed that KLF4 played critical roles in remodeling chromatin accessibility in porcine early embryos.Knocking down of KLF4 led to the reduction of chromatin accessibility in early embryos,whereas KLF4 overexpression promoted the chromatin openness in porcine blastocysts.Furthermore,KLF4 deficiency resulted in mitochondrial dysfunction and developmental failure of porcine embryos.In addition,we found that overexpression of KLF4 in blastocysts promoted lipid droplet accumulation,whereas knockdown of KLF4 disrupted this process.Taken together,our study revealed the chromatin accessibility dynamics and identified KLF4 as a key regulator in chromatin accessibility and cellular metabolism during porcine preimplantation embryo development. | Wei Zhu Guowei Bu Ruifeng Hu Jixiang Zhang Lianyong Qiao Kai Zhou Tingting Wang Qiao Li Jingjing Zhang Linhui Wu Yali Xie Taotao Hu Shichun Yang Jiaqi Guan Xiaoyu Chu Juanjuan Shi Xia Zhang Falong Lu Xin Liu Yi-Liang Miao | 2024 | Science China(Life Sciences)2024，67，1： | 0 |
| 18 | Forecast Service of An Extreme Rainstorm Process in Bayannur City,Inner Mongolia in 2022显示文摘On August 1,2022,a rainstorm process occurred in Bayannur City,Inner Mongolia.An extreme precipitation event occurred in Wuyuan County,Urat Middle Banner and Urat Front Banner,causing rainstorm,flood,strong convective wind and other disasters,thereby resulting in crop damage,livestock death and other losses.Meteorological departments made a series of forecast and early warning,meteorological service and basin joint prevention for the rainstorm process,set an example for dealing with the rainstorm disaster,and accumulated experience for the forecast service of rainstorm in future. | Ruifeng ZHAO Ni YAN Linshengjie SHI Ting HOU | 2022 | Meteorological and Environmental Research2022，13，6： | 0 |
| 19 | Genetic Architecture of Childhood Kidney and Urological Diseases in China显示文摘Kidney disease is manifested in a wide variety of phenotypes,many of which have an important hereditary component.To delineate the genotypic and phenotypic spectrum of pediatric nephropathy,a multicenter registration system is being imple-mented based on the Chinese Children Genetic Kidney Disease Database(CCGKDD).In this study,all the patients with kidney and urological diseases were recruited from 2014 to 2020.Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features.The genetic diagnosis was confirmed in 883 of 2256(39.1%)patients from 23 provinces in China.Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome(SRNS,23.5%),glomerulonephritis(GN,32.2%),congenital anomalies of the kidney and urinary tract(CAKUT,21.2%),cystic renal disease(3.9%),renal calcinosis/stone(3.6%),tubulopathy(9.7%),and chronic kidney disease of unknown etiology(CKDu,5.8%).The pathogenic variants of 105 monogenetic disorders were identified.Ten distinct genomic disorders were identified as pathogenic copy number variants(CNVs)in 11 patients.The diagnostic yield differed by subgroups,and was highest in those with cystic renal disease(66.3%),followed by tubulopathy(58.4%),GN(57.7%),CKDu(43.5%),SRNS(29.2%),renal calcinosis/stone(29.3%)and CAKUT(8.6%).Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions.We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed.Our data demonstrate the utility of family-based exome sequencing,and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease. | Ye Fang Hua Shi Tianchao Xiang Jiaojiao Liu Jialu Liu Xiaoshan Tang Xiaoyan Fang Jing Chen Yihui Zhai Qian Shen Guomin Li Li Sun Yunli Bi Xiang Wang Yanyan Qian Bingbing Wu Huijun Wang Wenhao Zhou Duan Ma Jianhua Mao Xiaoyun Jiang Shuzhen Sun Ying Shen Xiaorong Liu Aihua Zhang Xiaowen Wang Wenyan Huang Qiu Li Mo Wang Xiaojie Gao Yubin Wu Fang Deng Ruifeng Zhang Cuihua Liu Li Yu Jieqiu Zhuang Qing Sun Xiqiang Dang Haitao Bai Ying Zhu Siguang Lu Bili Zhang Xiaoshan Shao Xuemei Liu Mei Han Lijun Zhao Yuling Liu Jian Gao Ying Bao Dongfeng Zhang Qingshan Ma Liping Zhao Zhengkun Xia Biao Lu Yulong Wang Mengzhun Zhao Jianjiang Zhang Shan Jian Guohua He Huifeng Zhang Bo Zhao Xiaohua LI Feiyan Wang Yufeng Li Hongtao Zhu Xinhui Luo Jinghai Li Jia Rao Hong Xu | 2021 | Phenomics2021，1，3： | 0 |
| 20 | Divergent Synthesis of Organofluorinated Molecules from Titanium Mediated Deoxygenation of Free Alcohols显示文摘Comprehensive Summary Alcohols as among the most widely occurring organic compounds known,deoxygenative transformations of free alcohols as partners in radical addition reactions remain formidable challenges with great opportunities to achieve new and useful transformations.Herein,we report a protocol via C—O bond cleavage and C—C bond-forming reaction of trifluoromethyl alkenes with free alcohols assisted by titanium reagents via a deoxygenative radical strategy,enabling the divergent synthesis for functional-group-rich organofluorinated compounds in high efficiencies.In this transformation,tertiary alcohols by Ti-catalysis could be converted to trifluoromethyl alkanes without defluorination in acidic conditions,while benzyl alcohols are employed by Ti-mediated activation to supply the gem-difluoroalkenes with defluorination in the presence of a base.This protocol is applicable for a broad range of trifluoromethyl alkenes with good functional group tolerance and a variety of tertiary alcohols and benzyl alcohols(including primary。 | Hongjun Tian Ruifeng Zhang Lei Shi Can Zha Xiaoming Wang | 2023 | Chinese Journal of Chemistry2023，41，15： | 0 |
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