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| 1 | Proton pump inhibitor pantoprazole abrogates adriamycin-resistant gastric cancer cell invasiveness via suppression of Akt/GSK-β/β-catenin signaling and epithelial–mesenchymal transition显示文摘 | Bin Zhang Yan Yang Xiaoting Shi Wanyu Liao Min Chen Alfred Sze-Lok Cheng Hongli Yan Cheng Fang Shu Zhang Guifang Xu Shanshan Shen Shuling Huang Guangxia Chen Ying Lv Tingsheng Ling Xiaoqi Zhang Lei Wang Yuzheng Zhuge Xiaoping Zou | 2014 | Cancer Letters2014,,: | 2 |
| 2 | Study ofmalondialdehyde (MDA) content, superoxide dismutase (SOD) andglutathione peroxidase (GSH-Px) activities in chickens infected withavian infectious bronchitis virus显示文摘 | WANG Haifeng ZHONG Xiuhui SHI Wanyu | 2011 | African Journal of Biotechnology2011,10,45: | 1 |
| 3 | Engineering Sodium Metal Anode with Sodiophilic Bismuthide Penetration for Dendrite-Free and High-Rate Sodium-Ion Battery显示文摘Sodium(Na)metal batteries with a high volumetric energy density that can be operated at high rates are highly desirable.However,an uneven Na-ion migration in bulk Na anodes leads to localized deposition/dissolution of sodium during high-rate plating/stripping behaviors,followed by severe dendrite growth and loose stacking.Herein,we engineer the Na hybrid anode with sodiophilic Na_(3)Bi-penetration to develop the abundant phase-boundary ionic transport channels.Compared to intrinsic Na,the reduced adsorption energy and ion-diffusion barrier on Na_(3)Bi ensure even Na^(+)nucleation and rapid Na^(+)migration within the hybrid electrode,leading to uniform deposition and dissolution at high current densities.Furthermore,the bismuthide enables compact Na deposition within the sodiophilic framework during cycling,thus favoring a high volumetric capacity.Consequently,the obtained anode was endowed with a high current density(up to 5 mA∙cm^(−2)),high areal capacity(up to 5 mA∙h∙cm^(−2)),and long-term cycling stability(up to 2800 h at 2 mA∙cm^(−2)). | Wanyu Zhao Min Guo Zhijun Zuo Xiaoli Zhao Huanglin Dou Yijie Zhang Shiying Li Zichen Wu Yayun Shi Zifeng Ma Xiaowei Yang | 2022 | Engineering2022,8,4: | 0 |
| 4 | Hsa_circ_0002137 stabled by LIN28B promotes osteosarcoma cell growth through the hsa-miR-1246/BCL2 axis显示文摘Circular RNAs(circRNAs)are a novel class of non-coding RNA that have recently shown to have huge capabilities in the regulation of gene expression at the posttranscriptional level.Growing evidence has indicated that circRNAs could serve as competing endogenous RNAs(ceRNAs)to sponge microRNAs(miRNAs)and suppress functions of targeted miRNAs.Osteosarcoma(OS)is the most common malignant primary bone cancer.Hsa_circ_0002137 is upregulated in OS.However,the role of hsa_circ_0002137 in OS remains unclear.Using miRNA pull-down assay,we showed that cir_0002137 sponged hsa-miR-1246,and BCL2 apoptosis regulator(BCL2)mRNA was a potential target of hsa-miR-1246 in human osteosarcoma(HOS)cells.Further,we found that hsa_cir_0002137 could enhance the expression of BCL2 hsa-miR-1246 and promote HOS cell growth through sponging hsa-miR-1246.Moreover,RNA binding protein immunoprecip itation(RIP)assay revealed that lin-28 homolog B(LIN28B)protein associated with hsa_circ_0002137,and LIN28B could increase hsa_circ_0002137 stability and thus accelerate OS cell growth.Our work was the first to study the functions of hsa_circ_0002137,has-miR-1246 and LIN28B in OS,and these results may provide novel therapeutic targets for OS treatment. | FEI ZHANG JIANZHONG LAI RONGHAN HE YI SHI KUN XU SHIHAI JIANG TANGZHAO LIANG WANYU ZHAO WEIDA REN LEI ZHU SONG JIN KUN WANG | 2022 | BIOCELL2022,46,3: | 0 |
| 5 | Automated cone photoreceptor cell identication in confocal adaptive optics scanning laser ophthalmoscope images based on object detection显示文摘Cone photoreceptor cell identication is important for the early diagnosis of retinopathy.In this study,an object detection algorithm is used for cone cell identication in confocal adaptive optics scanning laser ophthalmoscope(AOSLO)images.An effectiveness evaluation of identication using the proposed method reveals precision,recall,and F_(1)-score of 95.8%,96.5%,and 96.1%,respectively,considering manual identication as the ground truth.Various object detection and identication results from images with different cone photoreceptor cell distributions further demonstrate the performance of the proposed method.Overall,the proposed method can accurately identify cone photoreceptor cells on confocal adaptive optics scanning laser ophthalmoscope images,being comparable to manual identication. | Yiwei Chen Yi He Jing Wang Wanyue Li Lina Xing Xin Zhang Guohua Shi | 2022 | Journal of Innovative Optical Health Sciences2022,15,1: | 0 |
| 6 | Existence of a Heterogeneous Pathway in Palladium-Catalyzed Carbon–Carbon Coupling Reaction:Evidence from Ag@Pd_(3)Cu Intermetallic Nanoplates显示文摘Palladium(Pd)-catalyzed cross-coupling reaction is a widely studied process with significant economic interest and represents one of the most successful nanocatalytic examples.Owing to the observed leaching of Pd ions from both monometallic and short-range-ordered Pd bimetallic nanocatalysts,there is ambiguity regarding whether the coupling reaction has a heterogeneous component.Herein,facilitated by theoretical calculations,we discovered that the Pd ion leaching-free Pd_(3)Cu intermetallic compound was able to catalyze the cross-coupling reaction heterogeneously with activity comparable with that of Pd ions leached from monometallic Pd.The observation that Pd_(3)Cu acted as a heterogeneous catalyst was further confirmed by the reaction-promoting effect of hot electrons generated by the Ag core in Ag@Pd_(3)Cu nanoplates upon photon adsorption and could only participate in the reaction on the surface of the nanocatalyst.Additionally,it demonstrated experimentally the effectiveness of the heterogeneous route in the coupling reaction.This study shows that the combination of plasmonic catalysis and intermetallic compounds is a promising strategy for designing robust nanocatalysts to synthesize value-added chemicals. | Rui Liu Cuihong Xu Yanan Chen Huachao Zhao Jiefang Sun Zuoliang He Wanyu Shan Gang Li Qiantao Shi Liping Fang Jingfu Liu Guibin Jiang | 2022 | CCS Chemistry2022,4,2: | 0 |
| 7 | Advances in bismuth-telluride-based thermoelectric devices: Progress and challenges显示文摘By effectively converting waste heat into electricity,thermoelectric materials and devices can provide an alternative approach to tackle the energy crisis.Amongst thermoelectric materials,bismuth telluride(Bi_(2)Te_(3))and its derivatives exhibit high figure of merit ZT values in the near-room-temperature region and show great potential for application in thermoelectric devices.Considering the rapid development of Bi_(2)Te_(3)-based thermoelectric materials and their devices in the last few years,a short and systematic review is much needed.Here,we sum-marize the novel designs,properties,and applications of Bi_(2)Te_(3)-based thermoelectric devices in different contexts,including wearable,portable,implantable,and cross-disciplinary applications.The challenges and outlook for Bi_(2)Te_(3)-based thermoelectric devices are also considered.This work will guide the future development of Bi_(2)Te_(3)-based thermoelectric devices that target broader and more practical applications. | Tianyi Cao Xiao-Lei Shi Meng Li Boxuan Hu Wenyi Chen Wei-Di Liu Wanyu Lyu Jennifer MacLeod Zhi-Gang Chen | 2023 | eScience2023,3,3: | 0 |