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| 1 | Biogenesis and regulation of the let-7 miRNAs and their functional implications显示文摘let-7 miRNA 是在线虫, Caenorhabditis elegans,和它的生物功能表演发现的第一 miRNAs 之一到人的从线虫的进化保存的高水平。在 C 不同。elegans,高级动物有 let-7 miRNAs 的多重 isoforms;一个一致序列把种子顺序和这些 isoforms 称为的这些 isoforms 份额被分成 let-7 miRNA 家庭。let-7 家庭的表示为发展预定和肿瘤 suppressor 功能被要求,但是必须为干细胞的自强被压制。因此, let-7 miRNA 生物的续生说必须小心地被控制。产生 let-7 miRNA,一个主要抄本被 RNA 聚合酶 II 生产然后随后由 Drosha/DGCR8, TUTase,和 Dicer 处理了。因为 let-7 处理的 dysregulation 是有害的, let-7 的生物的续生说被细胞的因素紧调整,例如 RNA 有约束力的蛋白质, LIN28A/B 和 DIS3L2。在这评论,我们讨论 let-7 miRNAs 的生物函数和生物的续生说,集中于在脊椎动物的 let-7 生物的续生说的规定的分子的机制,例如鼠标和人。 | Hosuk Lee Sungwook Han Chang Seob Kwon Daeyoup Lee | 2016 | Protein & Cell2016，7，2： | 24 |
| 2 | The ReaxFF reactive force-field: development, applications and future directions显示文摘The reactive force-field(ReaxFF)interatomic potential is a powerful computational tool for exploring,developing and optimizing material properties.Methods based on the principles of quantum mechanics(QM),while offering valuable theoretical guidance at the electronic level,are often too computationally intense for simulations that consider the full dynamic evolution of a system.Alternatively,empirical interatomic potentials that are based on classical principles require significantly fewer computational resources,which enables simulations to better describe dynamic processes over longer timeframes and on larger scales.Such methods,however,typically require a predefined connectivity between atoms,precluding simulations that involve reactive events.The ReaxFF method was developed to help bridge this gap.Approaching the gap from the classical side,ReaxFF casts the empirical interatomic potential within a bond-order formalism,thus implicitly describing chemical bonding without expensive QM calculations.This article provides an overview of the development,application,and future directions of the ReaxFF method. | Thomas P Senftle Sungwook Hong Md Mahbubul Islam Sudhir B Kylasa Yuanxia Zheng Yun Kyung Shin Chad Junkermeier Roman Engel-Herbert Michael J Janik Hasan Metin Aktulga Toon Verstraelen Ananth Grama Adri CT van Duin | 2016 | npj Computational Materials2016，，1： | 22 |
| 3 | 骨性强直的髋关节转换人工全髋关节置换术显示文摘目的评估人工全髋关节置换术(total hip arthroplasty,THA)治疗髋关节骨性强直的效果。方法自1987年8月~1998年2月,36例(38髋)行转换THA,平均术前融合时间20年1个月;平均随访8年11个月。结果Harris评分由(68.7±7.2)分提高到(87±6.1)分;髋关节总活动度增加180.7°±14.5°。关节疼痛缓解率为93.3%;平均肢体短缩由4.1cm降到1.6cm;人工关节存活率为86.8%。X线片示髋臼骨溶解6例,髋臼杯松动2例,股骨骨溶解4例,股骨柄松动1例。结论骨性强直的髋关节转换THA,可以缓解周围关节疼痛、增加髋关节的活动度、改善双下肢不等长和矫正髋关节畸形,提高生活质量。髋关节功能与臀中肌力量的恢复直接关联。 | 廉永云 Yoo Myungchul 裴福兴 冯卫 Chun Sungwook | 2006 | 中国骨与关节损伤杂志2006，21，8： | 9 |
| 4 | 有限负压下熔体硅中磷的挥发去除(英文)显示文摘对有限负压下熔体硅中磷的挥发去除进行研究。采用电子级硅配制Si-P合金,并采用GD-MS来检测实验前后硅中的磷含量。理论计算结果表明:在有限负压下,硅中的磷以P和P2的气体形式从熔体硅中挥发。实验结果显示:在温度1873K、真空度0.6-0.8Pa、熔炼3600s的条件下,熔体硅中的磷从0.046%(460ppmw)下降到0.001%(10ppmw)。实验结果与理论结果一致表明:当熔体硅中磷的含量大且炉腔内气压相对较高时,磷的去除与气压高度相关;而当炉腔气压很低时,磷的去除基本与气压无关。原因是在相对高磷含量的熔体硅中,磷主要以P2气体的形式挥发;在磷含量较低时,磷主要以单原子气体P的形式挥发。 | 郑淞生 Jafar SAFARIAN Seongho SEOK Sungwook KIM Merete TANGSTAD 罗学涛 | 2011 | Transactions of Nonferrous Metals Society of China2011，21，3： | 5 |
| 5 | Multiobjective genetic training and uncertainty quantification of reactive force fields显示文摘The ReaxFF reactive force-field approach has significantly extended the applicability of reactive molecular dynamics simulations to a wide range of material properties and processes.ReaxFF parameters are commonly trained to fit a predefined set of quantummechanical data,but it remains uncertain how accurately the quantities of interest are described when applied to complex chemical reactions.Here,we present a dynamic approach based on multiobjective genetic algorithm for the training of ReaxFF parameters and uncertainty quantification of simulated quantities of interest.ReaxFF parameters are trained by directly fitting reactive molecular dynamics trajectories against quantum molecular dynamics trajectories on the fly,where the Pareto optimal front for the multiple quantities of interest provides an ensemble of ReaxFF models for uncertainty quantification.Our in situ multiobjective genetic algorithm workflow achieves scalability by eliminating the file I/O bottleneck using interprocess communications.The in situ multiobjective genetic algorithm workflow has been applied to high-temperature sulfidation of MoO_(3) by H_(2)S precursor,which is an essential reaction step for chemical vapor deposition synthesis of MoS_(2) layers.Our work suggests a new reactive molecular dynamics simulation approach for far-from-equilibrium chemical processes,which quantitatively reproduces quantum molecular dynamics simulations while providing error bars. | Ankit Mishra Sungwook Hong Pankaj Rajak Chunyang Sheng Ken-ichi Nomura Rajiv K.Kalia Aiichiro Nakano Priya Vashishta | 2018 | npj Computational Materials2018，，1： | 3 |
| 6 | Surface engineering of inorganic nanoparticles for imaging and therapy显示文摘 | Jutaek Nam Nayoun Won Jiwon Bang Ho Jin Joonhyuck Park Sungwook Jung Sanghwa Jung Youngrong Park Sungjee Kim | 2013 | Advanced Drug Delivery Reviews2013，，5： | 2 |
| 7 | Zn-doped nickel iron(oxy)hydroxide nanocubes passivated by polyanions with high catalytic activity and corrosion resistance for seawater oxidation显示文摘Electrochemical water splitting to produce hydrogen fuel is a promising renewable energy-conversion technique.Large-scale electrolysis of freshwater may deplete water resources and cause water scarcity worldwide.Thus,seawater electrolysis is a potential solution to the future energy and water crisis.In seawater electrolysis,it is critical to develop cost-effective electrocatalysts to split seawater without chloride corrosion.Herein,we present zinc-doped nickel iron(oxy)hydroxide nanocubes passivated by negatively charged polyanions(NFZ-PBA-S)that exhibits outstanding catalytic activity,stability,and selectivity for seawater oxidation.Zn dopants and polyanion-rich passivated surface layers in NFZ-PBA-S could effectively repel chlorine ions and enhance corrosion resistance,enabling its excellent catalytic activity and stability for seawater oxidation. | So Jung Kim Heechae Choi Jeong Ho Ryu Kang Min Kim Sungwook Mhin Arpan Kumar Nayak Junghwan Bang Minyeong Je Ghulam Ali Kyung Yoon Chung Kyeong-Han Na Won-Youl Choi Sunghwan Yeo Jin Uk Jang HyukSu Han | 2023 | Journal of Energy Chemistry2023，，6： | 1 |
| 8 | Market pioneer and early follower survival risks:a contingency analysis of real- ly new versus incrementally new product-markets 显示文摘 | SUNGWOOK M MANOHAR U K | 2006 | Journal of Marketing2006，70，1： | 1 |
| 9 | 7,8-Dihydroxyflavone protects human keratinocytes against oxidativestress-induced cell damage via the ERK and PI3K/Akt-mediated Nrf2/HO-1 signalingpathways显示文摘 | Min Ryu Kyoung Kang Mei Piao Ki Kim Jian Zheng Cheng Yao Ji Cha Ha Chung Sang Kim Eunsun Jung Deokhoon Park Sungwook Chae Jin Hyun | 2014 | International Journal of Molecular Medicine2014，，4： | 1 |
| 10 | High-Q Fully Reconfigurable Tunable Bandpass Filters显示文摘 | JOSHIH SIGMARRSSON H H SUNGWOOK M | | 0，，12： | 1 |
| 11 | Novel carbon-doped TiO2 nanotube arrays with high aspect ratios for efficient solarwater splitting显示文摘 | JONG H P SUNGWOOK K ALLEN J B | 2006 | Nano Lett2006，6，1： | 1 |
| 12 | Simultaneous reduction in the exhaust emissions by a high exhaust gas recireulation ratio in a dimethyl - ether - fuelled diesel engine at a low - load operating condition 显示文摘 | Su Han Park Junepyo Cha Sungwook Park Chang Sik Lee | 2012 | Proceedings of the Institution of Mechanical Engineers Part D: Journal of Automobile Engineering2012，226，8： | 1 |
| 13 | Experimental study on spray break-up and atomization processes from GDI injector using high injection pressure up to 30MPa显示文摘 | Sanghoon Lee Sungwook Park | 2014 | International Journal of Heat and Fluid Flow2014，45，： | 1 |
| 14 | An optimal micropatterned end-effecter for enhancing frictional force on large intestinal surface显示文摘 | Lee SungHoon Kim YoungTae Yang Sungwook | 2010 | Materials & Interfaces2010，2，5： | 1 |
| 15 | Granulin Is a Soluble Cofactor for Toll-like Receptor 9 Signaling显示文摘 | Boyoun Park Ludovico Buti Sungwook Lee Takashi Matsuwaki Eric Spooner Melanie M. Brinkmann Masugi Nishihara Hidde L. Ploegh | 2011 | Immunity2011，，4： | 1 |
| 16 | Speech Enhancement for Non-stationary Noise Environment by Adaptive Wavelet Packet显示文摘 | Sungwook Chang Kwon Y Sung-il Yang | 2002 | IEEE Trans Pattern and Machine Intell2002，14，7： | 1 |
| 17 | Ultrasonic vehicle detector for side - fire implementation and extensive results including harsh conditions 显示文摘 | HYUNGJIN K JOOHYUNE L SUNGWOOK K | 2001 | Intelligent Transportation Systems IEEE Transactions on2001，2，3： | 1 |
| 18 | Factors associated with clinical and structural outcomes after arthroscopic rotator cuff repair with a suture bridge technique in medium, large, and massive tears显示文摘 | Sungwook Choi Myung Ku Kim Gyeong Min Kim Young-Ho Roh Im Kyung Hwang Hyunseong Kang | 2014 | Journal of Shoulder and Elbow Surgery2014，，： | 1 |
| 19 | DCT implementation with distributed Arithmetic显示文摘 | Yu Sungwook Earl E Swartzlander Jr | 2001 | IEEE Trans on Computers2001，50，9： | 1 |
| 20 | Active locomotion of a paddling-based capsule endoscope in an in vitro and in vivo experiment (with videos)显示文摘 | Hee Man Kim Sungwook Yang Jinseok Kim Semi Park Jae Hee Cho Jeong Youp Park Tae Song Kim Eui-Sung Yoon Si Young Song Seungmin Bang | 2010 | Gastrointestinal Endoscopy2010，，2： | 1 |
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