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		题名	作者	年代	出处	被引量
	1	Molecular Features of Colorectal Hyperplastic Polyps and Sessile Serrated Adenoma/Polyps From Korea显示文摘	Kyoung-Mee Kim Eui Jin Lee Sangyun Ha So Young Kang Kee-Taek Jang Cheol Keun Park Jin Yong Kim Young Ho Kim Dong Kyung Chang Robert Daniel Odze	2011	The American Journal of Surgical Pathology2011，，：	2
	2	Neurologic signs in relation to cognitive function in subcortical ischemic vascular dementia: a CREDOS (Clinical Research Center for Dementia of South Korea) study显示文摘	Seong Hye Choi SangYun Kim Seol-Heui Han Duk L. Na Doh-Kwan Kim Hae-Kwan Cheong Jae-Hong Lee Seong Yoon Kim Chang Hyung Hong So Young Moon Jay C. Kwon Jung Eun Kim Jee H. Jeong Hae Ri Na Kyung Ryeol Cha Sang Won Seo Yong S. Shim Jun-Young Lee Kyung Won Pa	2012	Neurological Sciences2012，，4：	1
	3	Association Between Functional Impairment, Depression, and Extrapyramidal Signs in Neuroleptic-Free Patients With Alzheimer Disease显示文摘	Junbae Choi Woojae Myung Jae Won Chung Hyo Shin Kang Duk L. Na Seong Yoon Kim Jae-Hong Lee Seol-Heui Han Seong Hye Choi SangYun Kim Seonwoo Kim Bernard J. Carroll Doh Kwan Kim	2013	Journal of Geriatric Psychiatry and Neurology2013，，3：	1
	4	Predictability of polygenic risk score for progression to dementia and its interaction with APOEε4 in mild cognitive impairment显示文摘Background:The combinatorial efect of multiple genetic factors calculated as a polygenic risk score(PRS)has been studied to predict disease progression to Alzheimer’s disease(AD)from mild cognitive impairment(MCI).Previous studies have investigated the performance of PRS in the prediction of disease progression to AD by including and excluding single nucleotide polymorphisms within the region surrounding the APOE gene.These studies may have missed the APOE genotype-specifc predictability of PRS for disease progression to AD.Methods:We analyzed 732 MCI from the Alzheimer’s Disease Neuroimaging Initiative cohort,including those who progressed to AD within 5 years post-baseline(n=270)and remained stable as MCI(n=462).The predictability of PRS including and excluding the APOE region(PRS_(+APOE) and PRS_(−APOE))on the conversion to AD and its interaction with the APOEε4 carrier status were assessed using Cox regression analyses.Results:PRS_(+APOE)(hazard ratio[HR]1.468,95%CI 1.335-1.615)and PRS_(−APOE)(HR 1.293,95%CI 1.157-1.445)were both associated with a signifcantly increased risk of MCI progression to dementia.The interaction between PRS_(+APOE) and APOEε4 carrier status was signifcant with a P-value of 0.0378.The association of PRSs with the progression risk was stronger in APOEε4 non-carriers(PRS_(+APOE):HR 1.710,95%CI 1.244-2.351;PRS_(−APOE):HR 1.429,95%CI 1.182-1.728)than in APOEε4 carriers(PRS_(+APOE):HR 1.167,95%CI 1.005-1.355;PRS_(−APOE):HR 1.172,95%CI 1.020-1.346).Conclusions:PRS could predict the conversion of MCI to dementia with a stronger association in APOEε4 noncarriers than APOEε4 carriers.This indicates PRS as a potential genetic predictor particularly for MCI with no APOEε4 alleles.	Jung‑Min Pyun Young Ho Park Keon‑Joo Lee SangYun Kim Andrew J.Saykin Kwangsik Nho	2021	Translational Neurodegeneration2021，10，3：	0

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