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1An atlas of CNV maps in cattle, goat and sheep显示文摘Copy number variation(CNV)is the most prevalent type of genetic structural variation that has been recognized as an important source of phenotypic variation in humans,animals and plants.However,the mechanisms underlying the evolution of CNVs and their function in natural or artificial selection remain unknown.Here,we generated CNV region(CNVR)datasets which were diverged or shared among cattle,goat,and sheep,including 886 individuals from 171 diverse populations.Using 9 environmental factors for genome-wide association study(GWAS),we identified a series of candidate CNVRs,including genes relating to immunity,tick resistance,multi-drug resistance,and muscle development.The number of CNVRs shared between species is significantly higher than expected(P<0.00001),and these CNVRs may be more persist than the single nucleotide polymorphisms(SNPs)shared between species.We also identified genomic regions under long-term balancing selection and uncovered the potential diversity of the selected CNVRs close to the important functional genes.This study provides the evidence that balancing selection might be more common in mammals than previously considered,and might play an important role in the daily activities of these ruminant species.Yongzhen Huang Yunjia Li Xihong Wang Jiantao Yu Yudong Cai Zhuqing Zheng Ran Li Shunjin Zhang Ningbo Chen Hojjat Asadollahpour Nanaei Quratulain Hanif Qiuming Chen Weiwei Fu Chao Li Xiukai Cao Guangxian Zhou Shudong Liu Sangang He Wenrong Li Yulin Chen Hong Chen Chuzhao Lei Mingjun Liu Yu Jiang 2021Science China(Life Sciences)2021,64,10:2
2A Hu sheep genome with the first ovine Y chromosome reveal introgression history after sheep domestication显示文摘The Y chromosome plays key roles in male fertility and reflects the evolutionary history of paternal lineages.Here,we present a de novo genome assembly of the Hu sheep with the first draft assembly of ovine Y chromosome(o MSY),using nanopore sequencing and Hi-C technologies.The o MSY that we generated spans 10.6 Mb from which 775 Y-SNPs were identified by applying a large panel of whole genome sequences from worldwide sheep and wild Iranian mouflons.Three major paternal lineages(HY1a,HY1b and HY2)were defined across domestic sheep,of which HY2 was newly detected.Surprisingly,HY2 forms a monophyletic clade with the Iranian mouflons and is highly divergent from both HY1a and HY1b.Demographic analysis of Y chromosomes,mitochondrial and nuclear genomes confirmed that HY2 and the maternal counterpart of lineage C represented a distinct wild mouflon population in Iran that diverge from the direct ancestor of domestic sheep,the wild mouflons in Southeastern Anatolia.Our results suggest that wild Iranian mouflons had introgressed into domestic sheep and thereby introduced this Iranian mouflon specific lineage carrying HY2 to both East Asian and Africa sheep populations.Ran Li Peng Yang Ming Li Wenwen Fang Xiangpeng Yue Hojjat Asadollahpour Nanaei Shangquan Gan Duo Du Yudong Cai Xuelei Dai Qimeng Yang Chunna Cao Weidong Deng Sangang He Wenrong Li Runlin Ma Mingjun Liu Yu Jiang 2021Science China(Life Sciences)2021,64,7:1
3The critical role of myostatin in differentiation of sheep myoblasts显示文摘Chenxi Liu Wenrong Li Xuemei Zhang Ning Zhang Sangang He Juncheng Huang Yubin Ge Mingjun Liu 2012Biochemical and Biophysical Research Communications2012,,3:1
4Predicting the intrusion intentions by observing system call sequences显示文摘Li Feng Xiaohong Guan Sangang Guo Yan Gao Peini Liu 2004Computers & Security2004,,3:1
5Proteomic analysis of wheat ( Triticum aestivum L.) hybrid necrosis显示文摘Qiyan Jiang Hui Chen Xinglai Pan Qianying Pan Yinhong Shi Xiurong Li Guiyun Zhang Yongjie Wang Sangang Xie Shihua Shen 2008Plant Science2008,,3:1
6Challenges and advances on low-temperature rechargeable lithiumsulfur batteries显示文摘Lithium-sulfur(Li-S)batteries have demonstrated the potential to conquer the energy storage related market due to the extremely high energy density.However,their performances at low temperature are still needed to be improved to broaden their applications.Therefore,in this review,the basic failure mechanisms and major challenges of Li-S battery at low temperature are categorized as the high desolvation barrier of Li^(+),uncontrolled nucleation and deposition of lithium,polysulfides clustering,and passivation of cathode by film like Li_(2)S.Targeting these major issues,strategies,and advances concerning the design of optimized electrolyte,composite cathode and functional separator are highlighted and discussed.Finally,the suggestions are proposed for the future development of practical Li-S battery working at low temperature scenarios,hoping to accelerate the commercialization process and bring revolution to the energy storage market.Yu Jiao Fan Wang Yuhong Ma Sangang Luo Yaoyao Li Anjun Hu Miao He Fei Li Dongjiang Chen Wei Chen Tianyu Lei Yin Hu 2023Nano Research2023,16,6:0
7EFFECTS OF TOXICANTS ON CHEMTAT MODELWITH TIME VARIABLE NUTRIENT INPUT ANDWASHOUT显示文摘The influence of toxicants on the competition of n populations for time variablenutriellt input rate and time variable washout rate in a chemostat model is investigated.After proving some qualitative properties of the solutions, the threshold between persistence and extinction of the populations has been obtained.MA Zhien(Department of Applied Mathematics, Xi’an Jiaotong University, Xi’an 710049, China)GUO Sangang(Department of Basic Sciences, Shaanxi institute Of Technology, Hanzhong 723003, China)P. Fergola C. Tenneriello(Department Of Mathematics and Applicatio 1998Systems Science and Mathematical Sciences1998,11,4:0
8Allele-specific expression and splicing provide insight into the phenotypic differences between thin- and fat-tailed sheep breeds显示文摘The sheep(Ovis aries) was one of the first grazing animals to be domesticated approximately 11,000 years ago in the Fertile Crescent(Chessa et al., 2009). Since domestication, a wide variety of sheep breeds with different production traitsand morphological characteristics have been shaped under the influence of natural and artificial selection. According to the fat content in tail, sheep can be mainly classified into two groups: thin-and fat-tailed breeds.Fei Wang Junjie Shao Sangang He Yingwei Guo Xiangyu Pan Yu Wang Hojjat Asadollahpour Nanaei Lei Chen Ran Li Han Xu Zhirui Yang Mingjun Liu Yu Jiang 2022Journal of Genetics and Genomics2022,49,6:0
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