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| 1 | Gastric cancer:Prevention,screening and early diagnosis显示文摘Gastric cancer continues to be an important healthcare problem from a global perspective. Most of the cases in the Western world are diagnosed at late stages when the treatment is largely ineffective. Helicobacter pylori(H. pylori) infection is a well-established carcinogen for gastric cancer. While lifestyle factors are important,the efficacy of interventions in their modification,as in the use of antioxidant supplements,is unconvincing. No organized screening programs can be found outside Asia(Japan and South Korea). Although several screening approaches have been proposed,including indirect atrophy detection by measuring pepsinogen in the circulation,none of them have so far been implemented,and more study data is required to justify any implementation. Mass eradication of H. pylori in high-risk areas tends to be cost-effective,but its adverse effects and resistance remain a concern. Searches for new screening biomarkers,including microRNA and cancer-autoantibody panels,as well as detection of volatile organic compounds in the breath,are in progress. Endoscopy with a proper biopsy follow-up remains the standard for early detection of cancer and related premalignant lesions. At the same time,new advanced high-resolution endoscopic technologies are showing promising results with respect to diagnosing mucosal lesions visually and targeting each biopsy. New histological risk stratifications(classifications),including OLGA and OLGIM,have recently been developed. This review addresses the current means for gastric cancer primary and secondary prevention,the available and emerging methods for screening,and new developments in endoscopic detection of early lesions of the stomach. | Victor Pasechnikov Sergej Chukov Evgeny Fedorov Ilze Kikuste Marcis Leja | 2014 | World Journal of Gastroenterology2014,20,38: | 64 |
| 2 | G.654.E光纤长距离传输性能研究显示文摘对ITU-T G.654E光纤的传输性能进行了研究,总结了该类型光纤的一些新的特性。研究结果表明,G.654.E光纤的品质因子(FOM——Figure of merit)比常规G.652光纤高3 d B左右,实际400G系统测试结果显示G.654.E光纤比G.652光纤的传输距离提升60%以上。同时也讨论了配有拉曼放大器的传输系统工作在G.654.E光纤(泵浦光工作在光纤截止波长以下)时出现的新特性。 | Sergejs Makovejs John Downie 董浩 Michael Mlejnek 陈皓 | 2018 | 邮电设计技术2018,,6: | 5 |
| 3 | Design of single-axis flexure hinges using continuum topology optimization method显示文摘The design of compliant hinges has been extensively studied in the size and shape level in the literature.This paper presents a method for designing the single-axis flexure hinges in the topology level.Two kinds of hinges,that is,the translational hinge and the revolute hinge,are studied.The basic optimization models are developed for topology optimization of the translational hinge and the revolute hinge,respectively.The objective for topology optimization of flexure hinges is to maximize the compliance in the desired direction meanwhile minimizing the compliances in the other directions.The constraints for accomplishing the translational and revolute requirements are developed.The popular Solid Isotropic Material with Penalization method is used to find the optimal flexure hinge topology within a given design domain.Numerical results are performed to illustrate the validity of the proposed method. | ZHU BenLiang ZHANG XianMin FATIKOW Sergej | 2014 | Science China(Technological Sciences)2014,57,3: | 4 |
| 4 | Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial显示文摘 | Claus R?del Torsten Liersch Heinz Becker Rainer Fietkau Werner Hohenberger Torsten Hothorn Ullrich Graeven Dirk Arnold Marga Lang-Welzenbach Hans-Rudolf Raab Heiko Sülberg Christian Wittekind Sergej Potapov Ludger Staib Clemens Hess Karin Weigang-K?hler G | 2012 | Lancet Oncology2012,,7: | 2 |
| 5 | GC–MS libraries for the rapid identification of metabolites in complex biological samples显示文摘 | Nicolas Schauer Dirk Steinhauser Sergej Strelkov Dietmar Schomburg Gordon Allison Thomas Moritz Krister Lundgren Ute Roessner-Tunali Megan G. Forbes Lothar Willmitzer Alisdair R. Fernie Joachim Kopka | 2005 | FEBS Letters2005,,6: | 2 |
| 6 | The Silk Road agenda of the Pan-Eurasian Experiment (PEEX) program显示文摘The Silk Road Economic Belt and the 21st-Century Maritime Silk Road(B&R)aims at facilitating the twenty-first Century economic development of China.However,climate change,air quality and related feedbacks are affecting the successful development of the environment and societies in the B&R geographical domain.The most urgent risks related to the atmospheric system,to the land system and to hydrospheric and cryospheric processes are changing climate-air quality interactions,air pollution,changing monsoon dynamics,land degradation,and the melting of Tibetan Plateau glaciers.A framework is needed in which a science and technology-based approach has the critical mass and expertise to identify the main steps toward solutions and is capable to implement this roadmap.The Pan-Eurasian Experiment(PEEX)program,initiated in 2012,aims to resolve science,technology and sustainability questions in the Northern Eurasian region.PEEX is now identifying its science agenda for the B&R region.One fundamental element of the PEEX research agenda is the availability of comprehensive ground-based observations together with Earth observation data.PEEX complements the recently launched international scientific program called Digital Belt and Road(DBAR).PEEX has expertise to coordinate the ground-based observations and initiate new flagship stations,while DBAR provides a big data platform on Earth observation from China and countries along the Belt and Road region.The DBAR and PEEX have joint interests and synergy expertise on monitoring on ecological environment,urbanization,cultural heritages,coastal zones,and arctic cold regions supporting the sustainable development of the Belt and Road region.In this paper we identify the research themes of the PEEX related Silk Road agenda relevant to China and give an overview of the methodological requirements and present the infrastructure requirements needed to carry out large scale research program. | Hanna K.Lappalainen Markku Kulmala Joni Kujansuu Tuukka Petaja Alexander Mahura Gerrit de Leeuw Sergej Zilitinkevich Merli Juustila Veli-Matti Kerminen Bob Bornstein Zhang Jiahua Xue Yong Qiu Yubao Liang Dong Liu Jie Guo Huadong | 2018 | Big Earth Data2018,2,1: | 2 |
| 7 | TNF-α antibodies are effective as ischemic preconditioning in reducing infarct size in rabbits显示文摘 | Sergej B Ines B Alexej D | 2003 | Am J Physiol2003,234,: | 1 |
| 8 | Strength distribution of particles under compression显示文摘 | Yevgeny Rozenblat Dmitri Portnikov Avi Levy Haim Kalman Sergej Aman Jürgen Tomas | 2011 | Powder Technology2011,,1: | 1 |
| 9 | The adaptive crossapproximation technique for the 3-D boundary element method显示文摘 | Stefan Kurz Oliver Rain Sergej Rjasanow | 2002 | IEEE Trans on Magnetics2002,38,2: | 1 |
| 10 | Gastritis staging: interobserver agreement by applying OLGA and OLGIM systems显示文摘 | Sergejs Isajevs Inta Liepniece-Karele Dainius Janciauskas Georgijs Moisejevs Viesturs Putnins Konrads Funka Ilze Kikuste Aigars Vanags Ivars Tolmanis Marcis Leja | 2014 | Virchows Archiv2014,,4: | 1 |
| 11 | Conductivity spectroscopy on melt processed polypropylene-multiwalled carbon nanotube composites:Recovery after shear and crystallization显示文摘 | Ingo Alig Dirk Lellinger Sergej M Dudkin | 2007 | Polymer2007,48,4: | 1 |
| 12 | Fano resonances in nanoscale structures 显示文摘 | Andrey E Miroshnichenko Sergej Flach Yuri S Kivshar | 2010 | Rev ModPhys2010,82,: | 1 |
| 13 | Implementation of self - sensing SPM cantilevers for nano - force Measurement in microrobotics 显示文摘 | Fahlbusch Stephan Fatikow Sergej | 2001 | Ultra Microscopy2001,,86: | 1 |
| 14 | Dielectric spectroscopy on meh processed polycarbonate-muhiwalled carbon nanotube composites 显示文摘 | Petra Pstschke Sergej M Dudkin Ingo Aligb | 2003 | Polymer2003,44,17: | 1 |
| 15 | A laterally sensitive colloidal probe for accurately measuring nanoscale adhesion of textured surfaces显示文摘Adhesiion assessment of nanoscale contacts is a critical capability for the development of future nanoelectromechanical systems and nanobiotechnology devices. However, experimental approaches to investigate interactions on micro- and nanostructured surfaces have predominantly been restricted to capturing adhesion force in the normal direction. This provides limited information about the multidimensional nature of surface texture and related interaction mechanisms. Here the design, fabrication, and application of a unique atomic force microscope probe is presented that consists of a focused ion beam-milled cantilever decorated with a colloidal particle. The probe is specifically developed for characterizing textured surfaces with lateral force feedback. Pull-off tests that map the adhesive interaction in microscale cavities are performed to exami ne the capability of the probe. Normal and lateral adhesive forces duri ng nano scale contact are accurately obtai ned and the adhesi on en ergy of the con tact interface is thus determi ned. An in-depth un dersta nding of the effects of surface texture and the correlati on of adhesi on and fricti on is dem on strated. The proposed methodology en ables dedicated in vestigatio ns of in terfacial in teracti on on various norvplanar surfaces. It can be used for un dersta nding the complex in terplay of adhesi on, con tact, and fricti on forces at nano scale, which may facilitate significant advances in challenging research areas such as fibrillar adhesion. | Soren Zimmermann Waldemar Klauser James Mead Shiliang Wang Han Huang Sergej Fatikow | 2019 | Nano Research2019,12,2: | 1 |
| 16 | 49A/G and CT60 polymorphisms of the cytotoxic T-lymphocyte-associated antigen 4 gene associated with autoimmune thyroid disease显示文摘 | Ajda Bicek Katja Zaletel Simona Gaberscek Edvard Pirnat Blaz Krhin Tanja Gmeiner Stopar Sergej Hojker | 2009 | Human Immunology2009,,10: | 1 |
| 17 | Surface geometric parameters proposal for the advanced control of abrasive waterjet technology 显示文摘 | Jan Valicek Sergej Hloch Drazan Kozak | 2009 | The International Journal of Advanced Manufacturing Technology2009,41,34: | 1 |
| 18 | Cetuximab inhibits thymidylate synthase in colorectal cells expressing epidermal growth factor receptor显示文摘 | SERGEJ S BETTINA S HERBERT L | 2008 | Proteomics Clin Appl2008,2,6: | 1 |
| 19 | Recep- tive field properties of single neurons in rat primary visual cortex 显示文摘 | SERGEJ V YVES S RAYMOND D | 1999 | Neurophysiology1999,82,: | 1 |
| 20 | Laser-hybrid welding of thick plates up to 32 mm using a 20 kW fiber laser显示文摘 | Michael R Sergej G Marco L | 2009 | Quarterly Journal of the Japan Welding Society2009,27,2: | 1 |