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| 1 | Generation of a precise Oct4-hrGFP knockin cynomolgus monkey model via CRISPR/Cas9-assisted homologous recombination显示文摘 | Yiqiang Cui Yuyu Niu Jiankui Zhou Yongchang Chen Yiwei Cheng Shangang Li Zongyong Ai Chu Chu Hong Wang Bo Zheng Xuejin Chen Jiahao Sha Xuejiang Guo Xingxu Huang Weizhi Ji | 2018 | Cell Research2018，28，3： | 13 |
| 2 | Synthesis of hyperbranched copolymers by combining enzymatic ring-opening polymerization and ATRP from a novel bifunctional initiator显示文摘亢奋的分叉的脂肪族的聚酯 P (epsilon -CL) 借助于 BHB 的催化 Novozyme435 的戒指洞聚合(ROP ) 被综合(2, 2 二度(hydroxymethyl ) 奶油的酸) 。以 P ( epsilon-CL )的氢氧根结束的链被 esteriflcation ofa-bromopropionyl 溴化物修改获得亢奋的分叉的 difunctional 宏开始者,它在圣库克尔姆泰塔的 theATRP 被使用在 ATRP 的反应被用作催化剂系统 polystyrene-block-poly 获得 thehyperbranched 共聚物(2,2二度( hydroxymethyl )奶油的酸)。共聚物被 NMR 和 GPC 证实。 | AI Peng CHEN Liang HU Dehua CHEN Yanhua LU Dongshuang ZHANG Bao SHA Ke WANG Jingyuan | 2006 | Chinese Science Bulletin2006，51，22： | 3 |
| 3 | Establishment and characterization of an astroglial cell line derived from the brain of half-smooth tongue sole(Cynoglossus semilaevis)显示文摘An astroglial cell line was established from the brain of half smooth tongue sole(Cynoglossus semilaevis)and was designated as CSAC.CSAC shows the morphological homogeneity of epithelial cells.The cell identity was tested by the presence of glial fibrillary acidic protein(GFAP),which was revealed by RT-PCR and immunofluorescence.The cell line was optimally maintained at 24 °C in minimum essential medium supplemented with HEPES,antibiotics,20%fetal bovine serum,2-Mercaptoethanol(2-Me) and basic fibroblast growth factor.Chromosome analysis revealed that the CSAC cells maintained a normal diploid chromosome number(2n=42).The fluorescent signals were observed in CSAC after the cells were transfected with green fluorescent protein(GFP) reporter plasmids.The CSAC cell line may serve as a valuable tool for studies on the potential functions of fish astroglial cells. | Tian-Zi WANG Ai SUN Na WANG Zhong-Kai CUI Song-Lin CHEN Zhen-Xia SHA | 2015 | Zoological Research2015，36，5： | 2 |
| 4 | Differentially expressed genes in human endometrial endothelial cells derived from eutop ic endometrium of patients with endometriosis compared with those from patients without endometriosis 显示文摘 | Sha quihua Wudong Ying Zhangliang et aI | 2007 | Hum Rep rod2007，22，12： | 1 |
| 5 | Fragmented QRS is associated with all- cause mortality and ventricular arrhytnmia in patients with idiopathic dilated cardiomypathy显示文摘 | Sha J Zhang S Tang M et ai | 2011 | Ann Noninvasive Electrocardiol2011，16，3： | 1 |
| 6 | Subdynamic programming optimization model on oil field development program显示文摘 | AI Wenguo | 2004 | Journal of Harbin Institute of Technology2004，11，6： | 1 |
| 7 | Stressed out about obesity: IREla XBP1 in metabolic disorders显示文摘 | Sha H He Y Yang L et aI | 2011 | Trends Endocrinol Metab2011，22，9： | 1 |
| 8 | Invasibility and recoverability of a plant community following invasion depend on its successional stages显示文摘Exotic species invasion represent important causes of harming the structure,function,and ecological environment in ecosystems.Yet,knowledge remains limited on the invasibility(invasion advantage of exotic species)and recoverability(recovery ability of native species)of a plant community following invasion depend on its successional stages.We selected three grasses of Setaria viridis,Artemisia gmelinii,and Bothriochloa ischemum representing early(E),middle(M),and late(L)successional species,respectively.Meanwhile,the grasses of Panicum virgatum was selected to represent exotic species(invasion species).Three types of soil were collected to treat the three E,M,and L successional species,and one type of soil was collected to treat the exotic species.We compared the performance of the three native plant species and one exotic species grown in their“own”and“other”soils in a 2-year greenhouse experiment.Our study showed that exotic species performed better in soils of E and M successional species than in the soil of L successional species.After exotic species removed,E and M successional species exhibited poor growth in the soil of exotic species,while that of L successional species performed poor in field exotic species soils,but performed better in soils disturbed by exotic species.Our study demonstrated that the invasibility and recoverability of native plant communities changed with vegetation succession. | Hongwei Xu Zemin Ai Qing Qu Minggang Wang Guobin Liu Sha Xue | 2022 | Soil Ecology Letters2022，4，2： | 1 |
| 9 | Is hybrid surgery of the cervical spine a good balance between fusion and arthroplasty? Pilot results from a single surgeon series显示文摘 | Hwee Weng Dennis Hey Choon Chiet Hong Ai Sha Long Hwan Tak Hee | 2013 | European Spine Journal2013，，1： | 1 |
| 10 | Combination cisplatin-vinorelbine for relapsed and chemotherapy-pretreated metastatic breast cancer显示文摘 | Sha mseddine AI Taher A Dabaja B | 1999 | Am J Clin Oncol1999，22，3： | 1 |
| 11 | 异质光照条件下克隆整合对入侵植物南美蟛蜞菊化感作用的影响显示文摘植物入侵已成为全球生态系统最严重的威胁之一。当具有克隆生长能力的入侵植物入侵或定殖到新的生境时,它们相互连接的分株可能受到异质光照的影响。在异质光照条件下,克隆整合对入侵植物化感作用的影响尚不清楚。为研究异质光照条件下克隆整合对入侵植物南美蟛蜞菊(Wedelia trilobata)化感作用的影响,采用两个连续分株的克隆片段进行了盆栽试验。较老的分株暴露在全光下,而年轻的分株则受到20%的全光照。同时,每个克隆片段的年轻分株与目标植株(一个番茄苗)在盆栽中相邻生长。南美蟛蜞菊的两个连续分株之间的匍匐茎设置切断和不切断两种处理。另外,两株番茄幼苗(一株作为目标植株)在盆栽中相邻生长作为对照。研究结果表明,当与目标植物相邻生长的南美蟛蜞菊分株之间的匍匐茎保持完整时,目标植株的生物量积累、叶片叶绿素和氮含量、叶绿素荧光参数和净光合速率及其根长和活性相较于匍匐茎切断处理显著降低。异质光照条件下连续两个分株之间碳水化合物的运输或共享可以增强20%全光处理下年轻分株的化感作用。克隆整合在异质光照条件下对具有克隆生长能力的入侵植物的入侵或定殖具有重要意义。 | Lei Pu Lang Cheng Ai Li Sha Liang Qing Wei Shulan Wu Linxuan He Xiangning Xu Ningfei Lei Jinsong Chen | 2022 | Journal of Plant Ecology2022，15，3： | 1 |
| 12 | Comparison of caspase-3 activation in tumor cells upon treatment of chemotherapeutic drugs using capillary electrophoresis显示文摘Caspases play important roles in cell apoptosis.Meas-urement of the dynamics of caspase activation in tumor cells not only facilitates understanding of the molecular mechanisms of apoptosis but also contributes to the development,screening,and evaluation of anticancer drugs that target apoptotic pathways.The fluorescence resonance energy transfer(FRET)technique provides a valuable approach for defining the dynamics of apop-tosis with high spatio-temporal resolution.However,FRET generally functions in the single-cell level and becomes ineffective when applied in the high throughput detection of caspase activation.In the cur-rent study,a FRET sensor was combined with capillary electrophoresis(CE)to achieve a high throughput method for cellular caspase detection.The FRET-based CE system is composed of a homemade CE system and a laser source for detecting the dynamics of caspase-3 in various cells expressing sensors of caspase-3 that have been treated with anticancer drugs,such as cell cycle-independent drug cisplatin and specific cell cycle drugs camptothecin and etoposide,as well as their combination with tumor necrosis factor(TNF).A posi-tive correlation between the caspase-3 activation ve-locity and drug concentration was observed when the cells were treated with cisplatin,but cells induced by camptothecin and etoposide did not show any apparent correlation with their concentrations.Moreover,differ-ent types of cells presented distinct sensitivities under the same drug treatment,and the combination treat-ment of TNF and anticancer drugs significantly accel-erated the caspase-3 activation process.Its high throughput capability and detection sensitivity make the FRET-based CE system a useful tool for investi-gating the mechanisms of anticancer drugs and anti-cancer drug screening. | Shuang Sha Honglin Jin Xiao Li Jie Yang Ruiting Ai Jinling Lu | 2012 | Protein & Cell2012，3，5： | 1 |
| 13 | 查看详情显示文摘 | Ai Sha N L H Liu J X Zhao W P Wang G R Guo H C | | 0，，： | 1 |
| 14 | Trigonometric variable shape parameter and exponent strategy for generalized multiquadric radial basis function approximation 显示文摘 | Xiang S Wang K M Ai Y T Sha Y D Shi H | 2012 | Applied Mathematical Modelling2012，36，： | 1 |
| 15 | 查看详情显示文摘 | Liu J X Ai Sha N L H He N Liu G D Liang C C Zhang X F Guo H C | | 0，，： | 1 |
| 16 | Exposure to Radon and Kidney Cancer:A Systematic Review and Meta-analysis of Observational Epidemiological Studies显示文摘Objective To evaluate the possible association between radon exposure and kidney cancer. Methods We performed a systematic review and a meta-analysis based on random effect models to provide a pooled association measure. Results We subjected 8 studies(overall relative risks and 95% confidence intervals: 1.01, 0.72 to 1.43, I^2 = 64.4%) to meta-analysis. Subgroup analysis revealed a marginally significant association between radon exposure and kidney cancer in studies conducted in Europe. Two population-based studies provided no evidence for the increased risk of kidney cancer in the general population. Conclusion The association between radon and kidney cancer remains unclear but cannot be excluded because of its biological plausibility and the limited number and quality of existing studies. Additional data from the general population and well-designed miner cohort studies are needed to reveal the real relationship between radon exposure and kidney cancer. | CHEN Bin YUAN Tan Wei WANG Ai Qing ZHANG Hong FANG Li Jun WU Qian Qian ZHANG Hong Bo TAO Sha Sha TIAN Hai Lin | 2018 | Biomedical and Environmental Sciences2018，31，11： | 0 |
| 17 | Hall Effect of an Oriented Superconducting YBa_(2)Cu_(3)O_(y) Film显示文摘A superconducting YBa_(2)Cu_(3)O_(y) thin film,which is well oriented at(001)direction and in which no grain boundary is observed in the resolution limit of scanning electron microscope micrograph,is selected for the Hall effect measurement from 80 to 220 K under a magnetic field of 3 T.A very narrow and negative peak of the Hall voltage(V_(H))is found in the superconducting£nuisition region.A linear dependence of the carrier concentration fnjjJ on temperature is found in the normal state.The appearance of such a negative peak is attributed to the intrinsic anisotropy of the Hall coefficient(Rn)related to the direction of the applied field and current. | HE Zhenhui SHA Jian WANG Shunxi CHENG Xiang'ai ZHOU Guien ZHANG Qirui SHI Wangzhou YAO Weiguo QI Zhenzhong | 1991 | Chinese Physics Letters1991，8，10： | 0 |
| 18 | Studies of the Anomaly of Hall Coefficient in High T_(c) Superconducting Thin Films显示文摘Measurements of the Hall coefficient(RH)were carried out for a polycrystalline YBa_(2)Cu_(3)O_(7-y) film,a well oriented YBa_(2)Cu_(3)O_(7-y) film and an oriented GdBa_(2)Cu_(3)O_(7-y) film.Sign change of RH was observed for the two YBa_(2)Cu_(3)O_(7-y) films near Tc,but not for the GdBa_(2)Cu_(3)O_(7-y) film which contains partly the component of(110)orientation.The RH anisotropy model proposed previously turns out to be incorrect.Why the YBa_(2)Cu_(3)O_(7-y) films experience sign change of RH while the GdBa_(2)Cu_(3)O_(7-y) film does not is tentatively investigated. | HE Zhenhui SHA Jian SU Zhenpeng CHENG Xiang ai WANG Shunxi FANG Minghu ZHANG Qirui ZHOU Xianyi YAO Weiguo QI Zhenzhong YI Huairen LI Hongcheng | 1991 | Chinese Physics Letters1991，8，6： | 0 |
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