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| 1 | Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2显示文摘Emerging and re-emerging RNA viruses occasionally cause epidemics and pandemics worldwide,such as the on-going outbreak of the novel coronavirus SARS-CoV-2.Herein,we identified two potent inhibitors of human DHODH,S312 and S416,with favorable drug-likeness and pharmacokinetic profiles,which all showed broad-spectrum antiviral effects against various RNA viruses,including influenza A virus,Zika virus,Ebola virus,and particularly against SARS-CoV-2.Notably,S416 is reported to be the most potent inhibitor so far with an EC5o of 17 nmol/L and an SI value of 10,505.88 in infec-ted cells.Our results are the first to validate that DHODH is an attractive host target through high antiviral efficacy in vivo and low virus replication in DHODH knock-out cells.This work demonstrates that both S312/S416 and old drugs(Leflunomide/Teriflunomide)with dual actions of antiviral and immuno-regulation may have clinical potentials to cure SARS-CoV-2 or other RNA viruses circulating worldwide,no matter such viruses are mutated or not. | Rui Xiong Leike Zhang Shiliang Li Yuan Sun Minyi Ding Yong Wang Yongliang Zhao Yan Wu Weijuan Shang Xiaming Jiang Jiwei Shan Zihao Shen Yi Tong Liuxin Xu Yu Chen Yingle Liu Gang Zou Dimitri Lavillete Zhenjiang Zhao Rui Wang Lili Zhu Gengfu Xiao Ke Lan Honglin Li Ke Xu | 2020 | Protein & Cell2020，11，10： | 14 |
| 2 | Functional analysis of the larval serum protein gene promoter from silkworm,Bombyx mori.显示文摘The regulation region of larval serum protein gene, Bombyx mori. (BmLSP), consisting of the first intron, the first exon, the central promoter region and 5′-upstream region, is cloned from genomic DNA from the silkworm va-riety of Suju譓inghu. Using PCR and restriction endonu-clease methods, a series of luciferase reporter plasmids, driven by different length of BmLSP promoters, are con-structed. Via the transient expression system in BmN cells, the effects of the regulation elements and foreign insect hor-mones on the BmLSP promoter activity are investigated. The results demonstrate that the promoter activity of BmLSP is 5.8- or 4.4-fold higher than that of BmLSPs whose first in-tron or the element in 5′-upstream region harboring the homologous sequence with the first intron of light-chain fib-roin gene (EHIF) is deleted, respectively, suggesting that both the first intron and EHIF contain the main positive cis-acting elements. However, the inactive mariner transposable ele-ment (MTE) in 5′-upstream region presents a negative effect. Furthermore, the effects of juvenile hormone analogue (JHA) on the BmLSP promoter activity show a typical dose-dependent manner, that is, low concentration treat-ments increase the BmLSP promoter activity and high con-centration treatments decrease it. Meanwhile, insect ecdy-sone (MH) treatments present no significant effect. | TANG Shunming, YI Yongzhu, SHEN Xingjia, ZHANG Zhifang, LI Yiren & HE Jialu Key Laboratory of Silkworm Biotechnology, Ministry of Agriculture, Sericultural Research Institute, Chinese Academy of Agricultural Sci-ences, Zhenjiang 212018, China Correspondence should be addressed to Zhang Zhifang (e-mail: zjsbsri@ public.zj.js.cn) | 2003 | Chinese Science Bulletin2003，48，23： | 13 |
| 3 | Investigation of Induced Distortions in a-Si∶H/a-SiN_x∶H Multilayers by Raman Scattering Technique显示文摘The a Si∶H/SiN x ∶H sample series are investigated by means of Raman scattering technique(RST). The result shows that due to the structural mismatch between a Si∶H and a SiN x ∶H, severe induced distortions are produced in the interface of the heterojunction, and these induced distortions tend towards a certain energy state. The ordering of the interface structure depends on the periodic number of multilayer thin films. | CAO Guo rong 1, GUO Shen kang 1, WANG Zhi chao 2, LIU Yin chun 2, SUN Mei xiang 2 (1.Dept. of Phys., Jiangsu University, Zhenjiang 212003, CHN 2.Dept. of Phys., Nanjing University, Nanjing 210093, CHN) | 2002 | Semiconductor Photonics and Technology2002，8，4： | 8 |
| 4 | Application of Spatial and Temporal Entropy Based on Multivariate Data for Measuring the Degree of Urban Function Mix显示文摘Quantifying the degree of urban function mix has great signifi cance to both urban planning practices and studies. This paper, fi rst of all, based on the data of points of interest(POIs), analyzes the spatial distribution patterns of urban functions in Beijing. Then according to the taxi GPS data with the origin and destination points(taxi-ODs), we identify the spatial and temporal pattern of the degree of urban function mix in Beijing. Finally, based on the information entropy model of the POIs and taxi-ODs, we establish a spatial entropy and a temporal entropy to quantitatively assess the degree of urban function mix, confirming by virtue of correlation analysis and regression analysis that the spatial entropy of POIs is closely associated with the temporal entropy of taxi-ODs, which proves that it is reasonable to assess the degree of urban function mix via these two entropies. As a result, the degree of urban function mix in Beijing is characterized by slowly decreasing from its core area along the 3rd and 4th Ring Roads to its periphery. In detail, there is the highest degree of urban function mix in Beijing's traditional core areas, including Zhongguancun, CBD(Central Business District), the Old Dongcheng District, the Old Xicheng District, and the area within the 2nd Ring Road; a higher degree in Wangjing area; and a low degree in Tiantongyuan and Huilongguan communities. The analytical results have initially achieved a more accurate identifi cation and quantitative evaluation on the degree of urban function mix, and can be taken as a supporting tool to analyze the comprehensiveness of urban functions. | Li Miaoyi Shen Zhenjiang Yang Tao Wang Jingyuan Kobayashi Fumihiko Li Min | 2015 | China City Planning Review2015，24，1： | 4 |
| 5 | Van der Waals epitaxy of ultrathin crystalline PbTe nanosheets with high near-infrared photoelectric response显示文摘Lead telluride(PbTe)is one of the reliable candidates for infrared(IR)optoelectronics with optimum band-gap as well as excellent photoelectric properties.Great interests had been paid on the growth and device applications with PbTe for the development of high-performance IR photodetectors especially those working in the near-infrared regime.Although a great deal of effort had been made to prepare PbTe nanostructures for miniaturized detectors,it is difficult to synthesize high-quality two-dimensional(2D)PbTe crystals due to its rock-salt non-layered structure.Herein,a facile strategy for controllable synthesis of ultrathin crystalline PbTe nanosheets by van der Waals epitaxy is reported.With an optimized growth temperature,which determines the morphology transit from triangular pyramid islands to regular square 2D planars,PbTe nanosheets in lateral size of tens of microns with thickness down to~7 nm are achieved.Meanwhile,ultrasensitive near-infrared detectors(NIRDs)based on the as-grown 2D PbTe nanosheets have been demonstrated with an ultrahigh responsivity exceeding 3,847 A/W at the wavelength of 1,550 nm under room temperature.Our approach demonstrates that 2D PbTe nanosheets have great latent capacity of developing high-performance miniaturized IR optoelectronic devices. | Xinxin Zhao Qing Yin Hao Huang Qiang Yu Bo Liu Jie Yang Zhuo Dong Zhenjiang Shen Benpeng Zhu Lei Liao Kai Zhang | 2021 | Nano Research2021，14，6： | 3 |
| 6 | Sulfur-deficient Co9S8/Ni3S2 nanoflakes anchored on N-doped graphene nanotubes as high-performance electrode materials for asymmetric supercapacitors显示文摘In this paper,Co9S8/Ni3S2 nanoflakes(NFs)with sulfur deficiencies were grown in-situ on N-doped graphene nanotubes(NGNTs).They were successfully prepared through electrodeposition followed by hydrogenation treatment,which is able to act as a self-supported electrode for asymmetric supercapacitors(ASCs).Combining the defect-rich active materials with highly conductive skeletons,the hybrid electrode N-GNTs@sd-Co9S8/Ni3S2NFs show ultrahigh specific capacity of^304 mA hg^-1 and prominent rate capability(capacity retention ratio of^85%even at 100 Ag^-1),and deliver a long cycling lifespan of^1.9%capacitance loss after 10000 cycles.In addition,an ASC was constructed using the as-synthesized composite electrode as the positive electrode and active carbon(AC)as the negative electrode.The fabricated device shows a high energy density of^45.1 Wh kg^-1 at^3.4 kW kg^-1 and superior cycling stability.This work substantiates a smart strategy to fabricate novel composite electrode materials for next-generation supercapacitors by incorporating riched deficiencies into nanostructures. | ZHAO Jian SONG GuanYing YUAN XiangCheng SHEN Tong JIANG QingYan MENG ALan LIN YuSheng LI ZhenJiang LI QingDang | 2020 | Science China(Technological Sciences)2020，63，4： | 2 |
| 7 | Study on visualization of townscape rules using VRML for public involvement显示文摘 | Shen Zhenjiang Mitsuhiko Kawakami | 2007 | Journal of Asian Architecture and Building2007，6，1： | 1 |
| 8 | Survivin small interfering RNA suppresses glioblastoma growth by inducing cellular apoptosis显示文摘A survivin small interfering RNA sequence specific for a human and mouse homogenous sequence was constructed.Survivin small interfering RNA could significantly inhibit glioma cell proliferation and induce apoptosis when it was transfected into either a human glioma cell line U251 or rat glioma C6 cells in vitro.In addition,treatment of rat orthotopic glioma models with survivin small interfering demonstrated the inhibition of glioma growth in vivo.Our experimental findings suggest that the use of RNA interference techniques to target the survivin sequence may be useful in the treatment of glioma. | Yanbo Liu Chunming Miao Zhenjiang Wang Xin He Weigao Shen | 2012 | Neural Regeneration Research2012，7，12： | 1 |
| 9 | Design and Synthesis of a Series of Novel Macrocycle Janus Kinase 2 Inhibitors显示文摘Summary of main observation and conclusion Macrocycle has attracted the attention of many researchers in the field of medicinal chemistry due to its unique advantages and good prospects,but the difficulties in drug design and synthesis of macrocycle limit its applications.In this study,a series of macrocyclic derivatives designed from anaplastic lymphoma kinase(ALK)inhibitor lorlatinib were synthesized as Janus kinase 2(JAK2)selective inhibitors.Among them,17f had the best inhibitory activity(IC50=0.177μmol·L^-1)and selectivity for JAK2 over JAK1 and JAK3,which indicated that design of the macrocyclic derivatives might be a feasible strategy for the discovery of novel selective JAK2 inhihitors. | Yanling Wang Huan Ge Disha Wang Huan He Lu Li Yanyan Diao Zihao Shen Lili Zhu Shiliang Li Zhenjiang Zhao Honglin Li | 2019 | Chinese Journal of Chemistry2019，37，12： | 1 |
| 10 | Structural self-reconstruction strategy empowering Ni-rich layered cathodes with low-strain for superior cyclabilities显示文摘The key to hindering the commercial application of Ni-rich layered cathode is its severe structural and interface degradation during the undesired phase transition(hexagonal to hexagonal(H2→H3)),degenerating from the build-up of mechanical strain and undesired parasitic reactions.Herein,a perovskite Li_(0.35)La_(0.55)TiO_(3)(LLTO)layer is built onto Ni-rich cathodes crystal to induce layered@spinel@perovskite heterostructure to solve the root cause of capacity fade.Intensive exploration based on structure characterizations,in situ X-ray diffraction techniques,and first-principles calculations demonstrate that such a unique heterostructure not only can improve the ability of the host structure to withstand the mechanical strain but also provides fast diffusion channels for lithium ions as well as provides a protective barrier against electrolyte corrosion.Impressively,the LLTO modified LiNi_(0.9)Co_(0.05)Mn_(0.05)O_(2)cathode manifests an unexpected cyclability with an extremely high-capacity retention of≈94.6%after 100 cycles,which is superior to the pristine LiNi_(0.9)Co_(0.05)Mn_(0.05)O_(2)(79.8%).Furthermore,this modified electrode also shows significantly enhanced cycling stability even withstanding a high cut-off voltage of 4.6 V.This surface self-reconstruction strategy provides deep insight into the structure/interface engineering to synergistically stabilize structure stability and regulate the physicochemical properties of Ni-rich cathodes,which will also unlock a new perspective of surface interface engineering for layered cathode materials. | Zhouliang Tan Yunjiao Li Xiaoming Xi Shijie Jiang Xiaohui Li Xingjie Shen Panpan Zhang Zhenjiang He | 2023 | Nano Research2023，16，4： | 0 |
| 11 | Design, Synthesis and Biological Evaluation of Potent and Selective S1PR1 Agonists for the Treatment of Ulcerative Colitis显示文摘The binding of Sphingosine-1-phosphate(S1P)with the S1PR1-5 plays a fundamental physiological role in a number of processes including vascular development and stabilization,lymphocyte migration and distribution.S1P-S1PR1 signal axis established roles in immune cell trafficking thus playing a therapeutic role in multiple sclerosis and inflammatory bowel disease.In this study,a series of oxadiazole derivatives were designed and synthesized as S1PR1 agonists based on rational drug design.Among them,compound 9i was identified as a potent and selective S1PR1 agonist with activities onβ-arrestin recruitment(EC50=0.36 nmol/L)and receptor internalization(EC50=8.09 nmol/L).Meanwhile,compound 9i displayed an oral bioavailability up to 93.6%.Based on its excellent activity to S1PR1 and pharmacokinetic properties,compound 9i effectively alleviated dextran sulfate sodium(DSS)-induced ulcerative colitis in mice at a dose of 0.1 mg/kg. | Huan He Mengting Xie Mengting Zhang Haiqin Zhang Huan Zhu Yuxian Fang Zihao Shen Rui Wang Zhenjiang Zhao Lili Zhu Xuhong Qian Honglin Li | 2022 | Chinese Journal of Chemistry2022，40，22： | 0 |
| 12 | MXRA7 is involved in megakaryocyte differentiation and platelet production显示文摘Matrix remodeling is a critical process in hematopoiesis.The biology of MXRA7,as a matrix remodeling associated gene,has still not been reported in hematopoietic process.Public databases showed that MXRA7 expressed in hematopoietic stem cells,suggesting that it may be involved in hematopoiesis.We found that the amounts of megakaryocytes were lower in bone marrow and spleen from Mxra7−/−mice compared with that from wild-type mice.Knock-out of MXRA7 also reduced the amount of platelet in peripheral blood and affected the function of platelets.Knock-out of MXRA7 inhibited hematopoietic stem/progenitor cells differentiate to megakaryocytes possibly through down-regulating the expression of GATA-1 and FOG-1.Moreover,knockdown of MXRA7 in MEG-01 cells could inhibit the cell proliferation and cell apoptosis.Knockdown of MXRA7 inhibited the differentiation of MEG-01 cells and proplatelet formation through suppressing the ERK/MAPK signaling pathway and the expression ofβ-tubulin.In conclusion,the current study demonstrated the potential significance of MXRA7 in megakaryocyte differentiation and platelet production.The novel findings proposed a new target for the treatment of platelet-related diseases,and much more investigations are guaranteed to dissect the mechanisms of MXRA7 in megakaryocyte differentiation and platelet production. | Zhenjiang Sun Benfang Wang Ying Shen Kunpeng Ma Ting Wang Yiqiang Wang Dandan Lin | 2023 | Blood Science2023，5，3： | 0 |
| 13 | 城市规划与管理的大数据支持:中国经验显示文摘本书介绍了在城市和区域规划以及智慧城市领域使用大数据的最新实践和研究,包括四大部分:第一部分是"用于探究人类行为与城市结构的社会大数据";第二部分是"用于探究城市空间识别的兴趣点数据";第三部分是"用于整合土地使用和交通规划的移动设备数据";第四部分是"用于城市管理的信息基础设施"。 | shen zhenjiang li miaoyi 李涛 皮亚奇 | 2017 | 城乡规划2017，，5： | 0 |
| 14 | Harnessing the Unique Features of 2D Materials toward Dendrite-free Metal Anodes显示文摘Electrochemically active metal anodes,such as lithium,sodium,potassium,and zinc,have attracted great research interests in the advanced rechargeable batteries owing to their superior theoretical energy densities.Unfortunately,the metal anodes suffer from the huge volume changes with loss of active materials during the plating and stripping processes,resulting in fast capacity decay.Moreover,the random growth of dendrites on the metal anodes will penetrate the separator,causing severe safety issues.Engineering metal anodes by introducing the 2D materials are widely investigated to alleviate these issues.Benefitting from the ultrathin structure feature and unique electrical properties,2D materials are regarded as one of the best host of metal anodes.Besides,the tunable active sites on basal plane enable 2D materials to achieve favorable interaction with metal anodes.Moreover,some 2D materials exhibit good mechanical strength and flexibility,serving as building block for the artificial solid electrolyte interphase.In this review,we mainly disclosed the correlations between the intrinsic properties of 2D materials and their functions in guiding uniform nucleation,controlling the growth of metals,and accommodating the volume change.Also,the challenges of 2D materials in metal anodes are well discussed.Finally,the future directions to develop highperformance metal anodes by taking advantage of these unique features of 2D materials are proposed. | Zhenjiang Cao Yongzheng Zhang Yanglansen Cui Jianan Gu Zhiguo Du Yongzheng Shi Kai Shen Hao Chen Bin Li Shubin Yang | 2022 | Energy & Environmental Materials2022，5，1： | 0 |
| 15 | Correction to:Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2显示文摘CORRECTION TO:PROTEIN CELL 2020,11(10):723–739 http://gffzzd3cc09b8251d45dfopf0xu0cwuk5566cv.ffgz.tsg.suse.edu.cn/10.1007/S13238-020-00768-W In the original publication the author’s name‘Dimitri Lavillete’is published incorrectly.The correct author name should be spelt as‘Dimitri Lavillette’is provided in this correction.OPEN ACCESS This article is licensed under a Creative Commons Attribution 4.0 International License,which permits use,sharing,adaptation,distribution and reproduction in any medium or format,as long as you give appropriate credit to the original author(s)and the source,provide a link to the Creative Commons licence,and indicate if changes were made.The images or other third party material in this article are included in the article's Creative Commons licence,unless indicated otherwise in a credit line to the material.If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use,you will need to obtain permission directly from the copyright holder.To view a copy of this licence,visit http://gffzzeb6f7f563f66445dhpf0xu0cwuk5566cv.ffgz.tsg.suse.edu.cn/licenses/by/4.0/. | Rui Xiong Leike Zhang Shiliang Li Yuan Sun Minyi Ding Yong Wang Yongliang Zhao Yan Wu Weijuan Shang Xiaming Jiang Jiwei Shan Zihao Shen Yi Tong Liuxin Xu Yu Chen Yingle Liu Gang Zou Dimitri Lavillette Zhenjiang Zhao Rui Wang Lili Zhu Gengfu Xiao Ke Lan Honglin Li Ke Xu | 2022 | Protein & Cell2022，13，10： | 0 |
| 16 | Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2显示文摘Figure 1.Discovery of novel and potent DHODHi and their anti-influenza A virus activities.(A)The discovery and design of S312 and S416.The detailed descriptions of the discovery workflow are in Method.Binding analysis of S312(B)and S416(C).Thermodynamic analysis of the binding of S312 and S416 to DHODH was carried out at 25 C on a MicroCal iTC200 instrument.Kinetic analysis of the binding of S312 and S416 to DHODH was performed with a Biacore T200 instrument. | Rui Xiong Leike Zhang Shiliang Li Yuan Sun Minyi Ding Yong Wang Yongliang Zhao Yan Wu Weijuan Shang Xiaming Jiang Jiwei Shan Zihao Shen Yi Tong Liuxin Xu Yu Chen Yingle Liu Gang Zou Dimitri Lavillete Zhenjiang Zhao Rui Wang Lili Zhu Gengfu Xiao Ke Lan Honglin Li Ke Xu | 2021 | Protein & Cell2021，12，1： | 0 |
| 17 | Zwitterionic ring-opening polymerization of macrocyclic ethyleneoxy-substituted carbonate:Access to cyclic PEG-like polycarbonate显示文摘The innovation in polymer design to rival conventional polyethylene glycol(PEG)is an important approach to achieving a more sustainable society.Here,cyclic PEG-like polycarbonates having high molecular weight(4.4–49.5 kg/mol)were enabled through zwitterionic ring-opening polymerization(ZROP)of macrocyclic carbonates(MCs)mediated by N-heterocyclic carbene(NHC).The thermodynamic behavior of polymerization depends on the ring size of monomers.During this process,the ZROP of 11-membered MC was driven by the change of enthalpy(ΔH_(p))which differed from the ZROP of 14-membered MC driven by the entropic change(ΔS_(p)).Cyclic polycarbonates depicted improved thermostability(T_(d5%)≥204℃)and higher glass transition temperatures(T_(g)>–40℃)in comparison to their linear analogues(T_(d5%)≤185℃,T_(g)~–50℃).In addition,the mechanism of ZROP of MC was addressed through computational study.A distinct mechanism of polymerization distinguishable from the well-known NHC-mediated ZROP of cyclic esters was revealed,where the zwitterion from nucleophilic addition to MC,i.e.tetrahedral intermediate,cannot be ring-opened probably due to the delocalization of negative charge on the carbonate group,but serves as an active center for the polymerization.In comparison to PEG,the attained polymer demonstrated comparable hydrophilic and biocompatible properties,as revealed by the results of contact angle and in vitro cytotoxicity studies,suggesting that cyclic polycarbonate hold the promise as the alternative of PEG. | Jin Huang Jinwen Li Rui Yan Yuanyuan Qu Fengzhen Guo Lei Shen Can-liang Ma Jie Sun Zhenjiang Li Kai Guo | 2024 | Chinese Chemical Letters2024，35，3： | 0 |
| 18 | A novelty strategy induced pinning effect and defect structure in Ni-rich layered cathodes towards boosting its electrochemical performance显示文摘Layered Ni-rich transition metal oxide is treated as the most promising alternative cathode due to their high-capacity and flexible composition.However,the severe lattice strain and slow Li-ion migration kinetics severely restrict their practical application.Herein,a novelty strategy induced pinning effect and defect structure in layered Ni-rich transition metal oxide cathodes is proposed via a facile cation(iron ion)/anion(polyanion)co-doping method.Subsequently,the effects of pinning effect and defect structure on element valence state,crystal structure,morphology,lattice strain,and electrochemical performance during lithiation/delithiation are systematically explored.The detailed characterizations(soft X-ray absorption spectroscopy(sXAS),in-situ X-ray diffraction(XRD),etc.)and density functional theory(DFT)calculation demonstrate that the pinning effects built-in LiNi_(0.9)Co_(0.05)Mn_(0.05)O_(2)materials by the dual-site occupation of iron ions on lithium and transition metal sites effectively alleviate the abrupt lattice strain caused by an unfavorable phase transition and the subsequent induction of defect structures in the Li layer can greatly reduce the lithium-ion diffusion barrier.Therefore,the modified LiNi_(0.9)Co_(0.05)Mn_(0.05)O_(2)exhibits a high-capacity of 206.5 mAh g^(-1)and remarkably enhanced capacity retention of 93.9%after 100 cycles,far superior to~14.1%of the pristine cathodes.Besides,an excellent discharge capacity of 180.1 mAh g^(-1)at 10 C rate is maintained,illustrating its remarkable rate capability.This work reports a pinning effect and defect engineering method to suppress the lattice strain and alleviate lithium-ion kinetic barriers in the Ni-rich layered cathodes,providing a roadmap for understanding the fundamental mechanism of an intrinsic activity modulation and structural design of layered cathode materials. | Zhouliang Tan Yunjiao Li Xiaoming Xi Shijie Jiang Xiaohui Li Xingjie Shen Panpan Zhang Zhenjiang He Junchao Zheng | 2022 | Journal of Energy Chemistry2022，31，9： | 0 |
| 19 | Satellite-Air-Terrestrial Cloud Edge Collaborative Networks:Architecture,Multi-Node Task Processing and Computation显示文摘Integrated satellite-terrestrial network(ISTN)has been considered a novel network architecture to achieve global three-dimensional coverage and ultra-wide area broadband access anytime and anywhere.Being a promising paradigm,cloud computing and mobile edge computing(MEC)have been identified as key technology enablers for ISTN to further improve quality of service and business continuity.However,most of the existing ISTN studies based on cloud computing and MEC regard satellite networks as relay networks,ignoring the feasibility of directly deploying cloud computing nodes and edge computing nodes on satellites.In addition,most computing tasks are transferred to cloud servers or offloaded to nearby edge servers,the layered design of integrated satellite-air-terrestrial architecture and the cloud-edge-device cooperative processing problems have not been fully considered.Therefore,different from previous works,this paper proposed a novel satellite-air-terrestrial layered architecture for cloud-edge-device collaboration,named SATCECN.Then this paper analyzes the appropriate deployment locations of cloud servers and edge servers in ISTN,and describes the processing flow of typical satellite computing tasks.For computing resource allocation problems,this paper proposed a device-edge-cloud Multi-node Cross-layer Collaboration Computing(MCCC)method to find the optimal task allo-cation strategy that minimizes the task completion delay and the weighted system energy consumption.Furthermore,the approximate optimal solutions of the optimization model are obtained by using successive convex approxi-mation algorithm,and the outstanding advantages of the proposed method in reducing system energy consumption and task execution delay are verified through experiments.Finally,some potential issues and directions for future research are highlighted. | Sai Liu Zhenjiang Zhang Guangjie Han Bo Shen | 2023 | Intelligent Automation & Soft Computing2023，37，9： | 0 |
| 20 | H-plasma In-situ Cleaning and Lattice Damage Elimination显示文摘This article discusses the silicon lattice damage induced during H-plasma in-situ cleaning and findsthat the substrate temperature, plasma power, processing time, all affect the extent of the distortion ofthe surface and its curability. | Chenguang GONG+ Fuchu SHEN Biguang YE Jian CHEN, Zhenjiang University, Hangzhou, 310027, China | 1993 | Journal of Materials Science & Technology1993，9，2： | 0 |
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