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| 1 | Identification of the candidate genes associated with cellular rejection in pig-to-human xenotransplantation显示文摘To identify the genes associated with cellular rejection in pig-to-human xenotransplantation, the suppression subtractive hybridization (SSH) was used in screening the up-regulated genes from a co-culture of human peripheral blood mononuclear cells (PBMCs) and porcine vascular endothelial cell line PIEC. The up-regulated cDNAs were cloned into pGEM-T Easy vector and then sequenced. Nucleic acid homology searches were performed using the BLAST program. A subtracted cDNA library including about 300 clones with the expected up-regulated genes was obtained. Twenty-four of these clones were analyzed by sequencing and homology comparison was made. These clones represent the genes of human perforin (PRF1), proteasome, lymphocyte specific interferon regulatory factor/interferon regulatory factor 4 (LSIRF/IRF 4), muscleblind-like (MBNL) protein and a porcine expressed sequence tag (EST) which has 81% homology with human oxidative-stress responsive 1 (OSR 1). These genes might be the candidate genes which are associated with cellular rejection in pig-to-human xenotransplantation. | HU Weimin, CHENG Jingqiu, LI Youping , LI Shengfu, LU Xiaofeng and WAN Lin(Laboratory of Transplant Engineering and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China) | 2002 | Progress in Natural Science:Materials International2002，12，9： | 3 |
| 2 | Artificial intelligence assisted light control and computational imaging through scattering media显示文摘Coherent optical control within or through scattering media via wavefront shaping has seen broad applications since its invention around 2007.Wavefront shaping is aimed at overcoming the strong scattering,featured by random interference,namely speckle patterns.This randomness occurs due to the refractive index inhomogeneity in complex media like biological tissue or the modal dispersion in multimode fiber,yet this randomness is actually deterministic and potentially can be time reversal or precompensated.Various wavefront shaping approaches,such as optical phase conjugation,iterative optimization,and transmission matrix measurement,have been developed to generate tight and intense optical delivery or high-resolution image of an optical object behind or within a scattering medium.The performance of these modula-tions,however,is far from satisfaction.Most recently,artifcial intelligence has brought new inspirations to this field,providing exciting hopes to tackle the challenges by mapping the input and output optical patterns and building a neuron network that inherently links them.In this paper,we survey the developments to date on this topic and briefly discuss our views on how to harness machine learning(deep learning in particular)for further advancements in the field. | Shengfu Cheng Huanhao Li Yunqi Luo Yuanjin Zheng Puxiang Lai | 2019 | Journal of Innovative Optical Health Sciences2019，，4： | 2 |
| 3 | Metal-organic framework MIL-53(Al): synthesis, catalytic performance for the Friedel-Crafts acylation, and reaction mechanism显示文摘Metal-organic framework MIL-53(Al) was synthesized by a solvothermal method using aluminum nitrate as the aluminium source and 1,4-benzenedicarboxylic acid(H2BDC) as the organic ligand. The structure of samples was characterized by X-ray diffraction(XRD) and Fourier transform infrared spectroscopy(FT-IR). The catalytic activity and recyclability of MIL-53(Al) catalyst for the Friedel-Crafts acylation reaction of indole with benzoyl chloride were evaluated. The reaction conditions were optimized and a reaction mechanism was suggested. The results showed that the MIL-53(Al) catalyst exhibited good catalytic activity and recyclability for the Friedel-Crafts acylation reaction. When the molar ratio of indole and MIL-53(Al) catalyst was 1:0.06(n1:ncatalyst), the molar ratio of indole and benzoyl chloride was 1:3, and the solvent was dichloromethane, the conversion of indole could reach 97.1% and the selectivity of 3-acylindole could reach 81.1% at 25 °C after 8 h. The catalyst can be reused without significant degradation in catalytic activity. After the catalyst was reused five times, the conversion of indole was 87.6% and the selectivity of 3-acylindole was 79.5%. | Junlei Yan Sai Jiang Shengfu Ji Da Shi Hefei Cheng | 2015 | Science China Chemistry2015，58，10： | 2 |
| 4 | Inhibition of bacterial adhesion and biofilm formation on zwitterionicsurfaces显示文摘 | Cheng Gang Zhang Zheng Chen Shengfu | 2007 | Biomaterials2007，28，29： | 1 |
| 5 | Surface functional groups and redox property of modified activated carbons显示文摘一系列激活的碳(交流) 与目的作为激活代理人用 HNO3, H2O2 和蒸气被准备在交流准备过程把功能的组介绍给碳表面。激活代理人,功能的组和交流的氧化还原作用性质被温度节目解吸附作用(TPD ) 描绘的表面上的激活时间和周期的 Voltammetry (CV ) 的集中的效果。结果证明交流的内酯组与组们与 HNO3 的集中增加的激活时间,和 carboxyl 由 HNO3 增加激活。交流的羰基 / 奎宁组与激活时间和 H2O2 的集中由 H2O2 增加激活,尽管酸的组与 H2O2 的集中减少。CV 在 0 和 0.5 V 反映的氧化还原作用性质与功能的组由 TPD 描绘了的任何种氧是不同的,但是它与 SO2 催化氧化 / 氧化性质由 TPR 显示了一致。 | Zhang Xianglan Deng Shengfu Liu Qiong Zhang Yan Cheng Lei | 2011 | Mining Science and Technology2011，21，2： | 1 |
| 6 | Wavefront shaping: A versatile tool to conquer multiple scattering in multidisciplinary fields显示文摘Optical techniques offer a wide variety of applications as light-matter interactions provide extremely sensitive mechanisms to probe or treat target media.Most of these implementations rely on the usage of ballistic or quasi-ballistic photons to achieve high spatial resolution.However,the inherent scattering nature of light in biological tissues or tissue-like scattering media constitutes a critical obstacle that has restricted the penetration depth of non-scattered photons and hence limited the implementation of most optical techniques for wider applications.In addition,the components of an optical system are usually designed and manufactured for a fixed function or performance.Recent advances in wavefront shaping have demonstrated that scattering-or component-induced phase distortions can be compensated by optimizing the wavefront of the input light pattern through iteration or by conjugating the transmission matrix of the scattering medium. | Zhipeng Yu Huanhao Li Tianting Zhong Jung-Hoon Park Shengfu Cheng Chi Man Woo Qi Zhao Jing Yao Yingying Zhou Xiazi Huang Weiran Pang Hansol Yoon Yuecheng Shen Honglin Liu Yuanjin Zheng YongKeun Park Lihong V.Wang Puxiang Lai | 2022 | The Innovation2022，3，5： | 1 |
| 7 | Learning-based super-resolution interpolation for sub-Nyquist sampled laser speckles显示文摘Information retrieval from visually random optical speckle patterns is desired in many scenarios yet considered challenging.It requires accurate understanding or mapping of the multiple scattering process,or reliable capability to reverse or compensate for the scattering-induced phase distortions.In whatever situation,effective resolving and digitization of speckle patterns are necessary.Nevertheless,on some occasions,to increase the acquisition speed and/or signal-to-noise ratio(SNR),speckles captured by cameras are inevitably sampled in the sub-Nyquist domain via pixel binning(one camera pixel contains multiple speckle grains)due to finite size or limited bandwidth of photosensors.Such a down-sampling process is irreversible;it undermines the fine structures of speckle grains and hence the encoded information,preventing successful information extraction.To retrace the lost information,super-resolution interpolation for such sub-Nyquist sampled speckles is needed.In this work,a deep neural network,namely SpkSRNet,is proposed to effectively up sample speckles that are sampled below 1/10 of the Nyquist criterion to well-resolved ones that not only resemble the comprehensive morphology of original speckles(decompose multiple speckle grains from one camera pixel)but also recover the lost complex information(human face in this study)with high fidelity under normal-and low-light conditions,which is impossible with classic interpolation methods.These successful speckle super-resolution interpolation demonstrations are essentially enabled by the strong implicit correlation among speckle grains,which is non-quantifiable but could be discovered by the well-trained network.With further engineering,the proposed learning platform may benefit many scenarios that are physically inaccessible,enabling fast acquisition of speckles with sufficient SNR and opening up new avenues for seeing big and seeing clearly simultaneously in complex scenarios. | HUANHAO LI ZHIPENG YU QI ZHAO YUNQI LUO SHENGFU CHENG TIANTING ZHONG CHI MAN WOO HONGLIN LIU LIHONG V.WANG YUANJIN ZHENG PUXIANG LAI | 2023 | Photonics Research2023，11，4： | 0 |
| 8 | Towards ideal focusing of diffused light via optical wavefront shaping显示文摘Multiple scattering can significantly scramble the amplitude and phase profile of an optical field.It obscures subtle observations but only speckle patterns can be seen,unlike the ballistic regime where the information or the optical field can be identified with limited distortions.Efficient optical manipulation including information transmission and precise focusing is therefore obstructed as light travels deep into turbidmedia such as fog,turbid fluids,and biological tissues. | Huanhao Li Zhipeng Yu Tianting Zhong Shengfu Cheng Puxiang Lai | 2023 | Advanced Photonics2023，5，2： | 0 |
| 9 | Physical origin and boundary of scalable imaging through scattering media:a deep learning-based exploration显示文摘Imaging through scattering media is valuable for many areas,such as biomedicine and communication.Recent progress enabled by deep learning(DL)has shown superiority especially in the model generalization.However,there is a lack of research to physically reveal the origin or define the boundary for such model scalability,which is important for utilizing DL approaches for scalable imaging despite scattering with high confidence.In this paper,we find the amount of the ballistic light component in the output field is the prerequisite for endowing a DL model with generalization capability by using a“one-to-all”training strategy,which offers a physical meaning invariance among the multisource data.The findings are supported by both experimental and simulated tests in which the roles of scattered and ballistic components are revealed in contributing to the origin and physical boundary of the model scalability.Experimentally,the generalization performance of the network is enhanced by increasing the portion of ballistic photons in detection.The mechanism understanding and practical guidance by our research are beneficial for developing DL methods for descattering with high adaptivity. | XUYU ZHANG SHENGFU CHENG JINGJING GAO YU GAN CHUNYUAN SONG DAWEI ZHANG SONGLIN ZHUANG SHENSHENG HAN PUXIANG LAI HONGLIN LIU | 2023 | Photonics Research2023，11，6： | 0 |
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