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| 1 | VIC distributed hydrological model to predict climate change impact in the Hanjiang Basin显示文摘The climate impact studies in hydrology often rely on climate change information at fine spatial resolution. However, the general circulation model (GCM), which is widely used to simulate future climate scenario, operates on a coarse scale and does not provide reliable data on local or regional scale for hydrological modeling. Therefore the outputs from GCM have to be downscaled to obtain the information fit for hydrologic studies. The variable infiltration capacity (VIC) distributed hydrological model with 9×9 km2 grid resolution was applied and calibrated in the Hanjiang Basin. Validation results show that SSVM can approximate observed precipitation and temperature data reasonably well, and that the VIC model can simulate runoff hydrograph with high model efficiency and low relative error. By applying the SSVM model, the trends of precipitation and temperature (including daily mean temperature, daily maximum temperature and daily minimum temperature) projected from CGCM2 under A2 and B2 scenarios will decrease in the 2020s (2011―2040), and increase in the 2080s (2071―2100). However, in the 2050s (2041―2070), the precipitation will be decreased under A2 scenario and no significant changes under B2 scenario, but the temperature will be not obviously changed under both climate change scenarios. Under both climate change scenarios, the impact analysis of runoff, made with the downscaled precipitation and temperature time series as input of the VIC distributed model, has resulted in a decreasing trend for the 2020s and 2050s, and an overall increasing trend for the 2080s. | GUO ShengLian GUO Jing ZHANG Jun CHEN Hua | 2009 | Science China(Technological Sciences)2009，52，11： | 23 |
| 2 | A review on TiO_2 nanotube arrays:Fabrication, properties, and sensing applications显示文摘Fabrication, properties, and sensing applications of TiO2 nanotubes have been reviewed, and the highly ordered TiO2 nanotube arrays made by anodic oxidation in fluoride-contained electrolytes highlighted. The effect of anodization parameters (electrolyte, pH, and voltage) on the titania nanotube size and shape were discussed. The excellent biocompatibility of TiO2, the high orienta- tion, the large surface area with tunable pore sizes, as well as the high electron transfer rate along with the nanotubes make TiO2 nanotube array an ideal substrate for the sensor's fabrication and application. The sensors based on the TiO2 nanotube arrays for sensing hydrogen, oxygen, humidity, glucose and hydrogen peroxide all exhibited low detection limit, high stability, very good reproducibility and high sensitivity. | YANG LiXia LUO ShengLian CAI QingYun YAO ShouZhuo | 2010 | Chinese Science Bulletin2010，55，4： | 11 |
| 3 | Nitrogen-doped graphene nanosheets as high efficient catalysts for oxygen reduction reaction显示文摘It is of great significance in exploring alternative catalysts to platinum (Pt)-based materials for oxygen reduction reaction (ORR),because this reaction is invariably involved in various fuel cells and metal-air batteries.We herein reported the nitrogen doped graphene nanosheets (NGNSs) with pore volume of as high as 3.42 m 3 /g and investigated their potential application as ORR catalysts,it was demonstrated the NGNSs featured high activity,improved kinetics and excellent long-term stability for ORR.The NGNSs were successfully used as cathode catalysts of microbial fuel cells (MFCs) and performed even better than the commercial Pt/C (Pt 10%) catalysts at the maximum power output. | CI SuQin WU YongMin ZOU JianPing TANG LongHua LUO ShengLian LI JingHong WEN ZhenHai | 2012 | Chinese Science Bulletin2012，57，23： | 7 |
| 4 | Biosorption of zinc(Ⅱ) from aqueous solution by dried activated sludge显示文摘The biosorption potential of dried activated sludge as a biosorbent for zinc(Ⅱ) removal from aqueous solution was investigated.The effects of initial pH,contact time,initial zinc ion concentration,and adsorbent dosage on the biosorption processes were determined,and the equilibrium data were modeled by the Langmuir and Freundlich isotherms.The Langmuir isotherm model (R 2=0.999) was proved to fit the equilibrium data much better than the Freundlich isotherm model (R 2=0.918).The monolayer adsorption capacity of dried activated sludge for zinc(Ⅱ) was found to be 17.86 mg/g at pH of 5 and 25°C.The kinetic data were tested using pseudo firstand second-order models.The results suggested that the pseudo second-order model (R 2 > 0.999) was better for the description of the adsorption behavior of zinc(Ⅱ) onto the dried activated sludge.Fourier transform infrared spectral analysis showed that the dominant mechanism of zinc(Ⅱ) biosorption onto the dried activated sludge was the binding between amide groups and zinc ions. | Chunping Yang Jiaqiang Wang Min Lei Gengxin Xie Guangming Zeng Shenglian Luo | 2010 | Journal of Environmental Sciences2010，22，5： | 6 |
| 5 | Drug-nanoencapsulated PLGA microspheres prepared by emulsion electrospray with controlled release behavior显示文摘The development of modern therapeutics has raised the requirement for controlled drug delivery system which is able to efficiently encapsulate bioactive agents and achieve their release at a desired rate satisfying the need of the practical system.In this study,two kind of aqueous model drugs with different molecule weight,Congo red and albumin from bovine serum(BSA)were nanoencapsulated in poly(DL-lactic-co-glycolic acid)(PLGA)microspheres by emulsion electrospray.In the preparation process,the aqueous phase of drugs was added into the PLGA chloroform solution to form the emulsion solution.The emulsion was then electrosprayed to fabricate drugnanoencapsulated PLGA microspheres.The morphology of the PLGA microspheres was affected by the volume ratio of aqueous drug phase and organic PLGA phase(V_(w)/V_(o))and the molecule weight of model drugs.Confocal laser scanning microcopy showed the nanodroplets of drug phase were scattered in the PLGA microspheres homogenously with different distribution patterns related to V_(w)/V_(o).With the increase of the volume ratio of aqueous drug phase,the number of nanodroplets increased forming continuous phase gradually that could accelerate drug release rate.Moreover,BSA showed a slower release rate from PLGA microspheres comparing to Congo red,which indicated the drug release rate could be affected by not only V_(w)/V_(o)but also the molecule weight of model drug.In brief,the PLGA microspheres prepared using emulsion electrospray provided an efficient and simple systemto achieve controlled drug release at a desired rate satisfying the need of the practices. | Shenglian Yao Huiying Liu Shukui Yu Yuanyuan Li Xiumei Wang Luning Wang | 2016 | Regenerative Biomaterials2016，3，5： | 5 |
| 6 | Gene expression profiling and mechanism study of neural stem cells response to surface chemistry显示文摘To declare the mechanisms of neural stem cells(NSCs)in response to material surface chemistry,NSCs were exposed to the self-assemble monolayers of alkanethiolates on gold surfaces terminated with amine(NH2),hydroxyl(OH)and methyl(CH3)for analysis.The morphological responses of NSCs were recorded;the gene expression profilings were detected by genechips;the gene expressions data of NSCs responded to different chemical groups were declared through the gene ontology term and pathway analyses.It showed that cells behaved dissimilar on the three chemical groups,the adhesion,proliferation and migration were easier on the NH2 and OH groups;the gene expressions of NSCs were induced differently,either,involved in several functional processes and signaling pathways.CH3 group induced genes enriched much in chemistry reactions and death processes,whereas many genes of cellular nucleotide metabolism were down-regulated.NH2 group induced NSCs to express many genes of receptors on membrane,and participated in cellular signal transduction of cell adhesion and interactions,or associated with axon growth.OH group was similar to NH2 group to induce the membrane response,but it also down regulated metabolism of cells.Therefore,it declared the chemical groups affected NSCs through inner way and the NH2,OH and CH3 groups triggered the cellular gene expression in different signaling pathways. | Ying Wang Shenglian Yao Qingyuan Meng Xiaolong Yu Xiumei Wang Fuzhai Cui | 2014 | Regenerative Biomaterials2014，1，1： | 4 |
| 7 | Two new approaches to dividing flood sub-seasons in flood season using the fractal theory显示文摘This paper is an attempt to analyze the hydrological phenomena’s non-linearity, randomicity, credibility and similarity. In the same season each year, the flood hydrograph is self-similar and exhibits fractal characteristics. It is an argument about using fractal theory. This paper presents two new approaches to dividing flood sub-seasons by using the fractal theory. Two approaches to calculating fractal dimensions are both the magnitude measurement in the temporal scale and the similarity measurement in the spacial scale. This paper chooses the sample series of the daily maximum discharge in the flood season from 1960 to 2002 at the Zhanghe Reservoir. Both results of the two new approaches to dividing flood sub-seasons by using fractal theory are the same. Both results of dividing flood-periods by using the fractal theory are uniform with the traditional approach. Compared with the traditional approach, fractal approaches have quantitative and objective characteristics and are convenient in calculation, and are widely used in practice. | FANG ChongHui GUO ShengLian DUAN YaHui DUONG Ductien | 2010 | Chinese Science Bulletin2010，55，1： | 4 |
| 8 | Development of an antimicrobial peptide-loaded mineralized collagen bone scaffold for infective bone defect repair显示文摘The repair of infective bone defects is a great challenge in clinical work.It is of vital importance to develop a kind of bone scaffold with good osteogenic properties and long-term antibacterial activity for local anti-infection and bone regeneration.A porous mineralized collagen(MC)scaffold containing poly(D,L-lactide-co-glycolic acid)(PLGA)microspheres loaded with two antibacterial synthetic peptides,Pac-525 or KSL-W was developed and characterized via scanning electron microscopy(SEM),porosity measurement,swelling and mechanical tests.The results showed that the MC scaffold embedded with smooth and compact PLGA microspheres had a positive effect on cell growth and also had antibacterial properties.Through toxicity analysis,cell morphology and proliferation analysis and alkaline phosphatase evaluation,the antibacterial scaffolds showed excellent biocompatibility and osteogenic activity.The antibacterial property evaluated with Staphylococcus aureus and Escherichia coli suggested that the sustained release of Pac-525 or KSL-W from the scaffolds could inhibit the bacterial growth aforementioned in the long term.Our results suggest that the antimicrobial peptides-loaded MC bone scaffold has good antibacterial and osteogenic activities,thus providing a great promise for the treatment of infective bone defects. | Yuzhu He Yahui Jin Xiaoxia Ying Qiong Wu Shenglian Yao Yuanyuan Li Huiying Liu Guowu Ma Xiumei Wang | 2020 | Regenerative Biomaterials2020，7，5： | 3 |
| 9 | Aligned fibrin/functionalized self-assembling peptide interpenetrating nanofiber hydrogel presenting multi-cues promotes peripheral nerve functional recovery显示文摘Nerve guidance conduits with hollow lumen fail to regenerate critical-sized peripheral nerve defects(15 mm in rats and 25 mm in humans),which can be improved by a beneficial intraluminal microenvironment.However,individual cues provided by intraluminal filling materials are inadequate to eliminate the functional gap between regenerated nerves and normal nerves.Herein,an aligned fibrin/functionalized self-assembling peptide(AFG/fSAP)interpenetrating nanofiber hydrogel that exerting synergistic topographical and biochemical cues for peripheral nerve regeneration is constructed via electrospinning and molecular self-assembly.The hydrogel possesses an aligned structure,high water content,appropriate mechanical properties and suitable biodegradation capabilities for nerve repair,which enhances the alignment and neurotrophin secretion of primary Schwann cells(SCs)in vitro,and successfully bridges a 15-mm sciatic nerve gap in rats in vivo.The rats transplanted with the AFG/fSAP hydrogel exhibit satisfactory morphological and functional recovery in myelinated nerve fibers and innervated muscles.The motor function recovery facilitated by the AFG/fSAP hydrogel is comparable with that of autografts.Moreover,the AFG/fSAP hydrogel upregulates the regeneration-associated gene expression and activates the PI3K/Akt and MAPK signaling pathways in the regenerated nerve.Altogether,the AFG/fSAP hydrogel represents a promising approach for peripheral nerve repair through an integration of structural guidance and biochemical stimulation. | Shuhui Yang Jinjin Zhu Changfeng Lu Yi Chai Zheng Cao Jiaju Lu Zhe Zhang He Zhao Yin-Yuan Huang Shenglian Yao Xiangdong Kong Peixun Zhang Xiumei Wang | 2022 | Bioactive Materials2022，7，2： | 3 |
| 10 | Oxygen migration triggering molybdenum exposure in oxygen vacancy-rich ultra-thin Bi_(2)MoO_(6) nanoflakes: Dual binding sites governing selective CO_(2) reduction into liquid hydrocarbons显示文摘Oxygen vacancy plays vital roles in regulating the electronic and charge distribution of the oxygen deficient materials.Herein,abundant oxygen vacancies are created during assembling the two-dimensional(2D)ultra-thin Bi_(2)MoO_(6) nanoflakes into three dimensional(3D)Bi_(2)MoO_(6) nanospheres,resulting in significantly improved performance for photocatalytical conversion of CO_(2) into liquid hydrocarbons.The increased performance is contributed by two primary sites,namely the abundant oxygen vacancy and the exposed molybdenum(Mo)atom induced by oxygen-migration,as revealed by the theoretical calculation.The oxygen vacancy(Ov)and uncovered Mo atom serving as dual binding sites for trapping CO_(2) molecules render the synchronous fixation-reduction process,resulting in the decline of activation energy for CO_(2) reduction from 2.15 eV on bulk Bi_(2)MoO_(6) to 1.42 eV on Ov-rich Bi_(2)MoO_(6).Such a striking decrease in the activation energy induces the efficient selective generation of liquid hydrocarbons,especially the methanol(C_(2)H_(5) OH)and ethanol(CH_(3) OH).The yields of CH_(3) OH and C_(2)H_(5) OH over the optimal Ov-Bi_(2)MoO_(6) is high up to 106.5 and 10.3μmol g^(-1) respectively,greatly outperforming that on the Bulk-Bi_(2)MoO_(6). | Weili Dai Jianfei Long Lixia Yang Shuqu Zhang Yong Xu Xubiao Luo Jianping Zou Shenglian Luo | 2021 | Journal of Energy Chemistry2021，30，10： | 3 |
| 11 | Probabilistic forecasting based on ensemble forecasts and EMOS method for TGR inflow显示文摘Probabilistic inflow forecasts can quantify the uncertainty involved in the forecasting process and provide useful risk information for reservoir management.This study proposed a probabilistic inflow forecasting scheme for the Three Gorges Reservoir(TGR)at 1-3 d lead times.The post-processing method Ensemble Model Output Statistics(EMOS)is used to derive probabilistic inflow forecasts from ensemble inflow forecasts.Considering the inherent skew feature of the inflow series,lognormal and gamma distributions are used as EMOS predictive distributions in addition to conventional normal distribution.Results show that TGR's ensemble inflow forecasts at 1-3 d lead times perform well with high model efficiency and small mean absolute error.Underestimation of forecasting uncertainty is observed for the raw ensemble inflow forecasts with biased probability integral transform(PIT)histograms.The three EMOS probabilistic forecasts outperform the raw ensemble forecasts in terms of both deterministic and probabilistic performance at 1-3 d lead times.The EMOS results are more reliable with much flatter PIT histograms,coverage rates approximate to the nominal coverage 89.47%and satisfactory sharpness.Results also show that EMOS with gamma distribution is superior to normal and lognormal distributions.This research can provide reliable probabilistic inflow forecasts without much variation of TGR5s operational inflow forecasting procedure. | Yixuan ZHONG Shenglian GUO Feng XIONG Dedi LIU Huanhuan BA Xushu WU | 2020 | Frontiers of Earth Science2020，14，1： | 3 |
| 12 | Projection of droughts and their socioeconomic exposures based on terrestrial water storage anomaly over China显示文摘Global warming has altered the thermodynamic and dynamic environments of the climate system, thus affecting the energy budget and water cycle process of the land-atmosphere system. Under changes in key hydrological elements such as precipitation, runoff, and terrestrial water storage, future drought variation remains a complex question. Existing studies have utilized terrestrial water storage anomaly(TWSA) in drought monitoring and assessment, but they usually focused on either drought duration or intensity, overlooking the multi-faced attributes of droughts as well as their socioeconomic impacts under a non-stationary condition. In this study, we first identify dry/wet conditions over China using GRACE/GRACE-FO satellite observations, and then evaluate the feedback effects of humidity and energy factors(e.g., sensible heat flux, latent heat flux,atmospheric relative humidity, and convective available potential energy) to drought events. Future changes in TWSA and dry/wet conditions are projected by eight Coupled Model Inter-comparison Project Phase 6(CMIP6) global climate models(GCMs)under three shared socioeconomic pathways(SSPs), with their biases corrected by a trend-preserving quantile mapping method.The time-varying Copula function of drought duration and intensity is constructed by a moving windows method, and future bivariate drought risks are quantified with the most likely realization method. The population and GDP affected by increasing drought risks are finally quantified based on the SSPs data. It is found that the land-atmosphere coupling effects closely interact with drought evolution, and the uneven distribution of water resources is projected to be further aggravated, with most areas of China will be threatened by continuous drying tendency. By the end of the century, the duration of moderate, severe and exceptional droughts in some regions of China will double, and the drought intensity will increase by over 80%. For the 50-year bivariate droughts during the historical period, their occurrence may increase by 5–10 times in several regions, and might affect about 35–55% of China’s population and GDP at the end of 21st century. | Jiabo YIN Shenglian GUO Yan YANG Jie CHEN Lei GU Jun WANG Shaokun HE Boyang WU Jinghua XIONG | 2022 | Science China Earth Sciences2022，65，9： | 2 |
| 13 | A macro - scale and semi-distributed monthly water balance model to predict climate change impacts in China 显示文摘 | Guo Shenglian Wang Jinxing Xiong Lihua | 2002 | Journal of Hydrology2002，268，14： | 1 |
| 14 | White fungus-like mesoporous Bi 2 S 3 ball/TiO 2 heterojunction with high photocatalytic efficiency in purifying 2,4-dichlorophenoxyacetic acid/Cr(VI) contaminated water显示文摘 | Lixia Yang Wensi Sun Shenglian Luo Yan Luo | 2014 | Applied Catalysis B: Environmental2014，，： | 1 |
| 15 | Joint operation and dynamic control of flood limiting water levels for cascade reser- voirs显示文摘 | CHEN Jionghong GUO Shenglian LI Yu | 2013 | Water Resource Management2013，27，： | 1 |
| 16 | Endoscopic papillary balloon dilatation versus endoscopic sphincterotomy in the treatment for choledocholithiasis: A meta‐analysis显示文摘 | YangyangLiu PeizhuSu SihengLin KunXiao PingyanChen ShengliAn FachaoZhi YangBai | 2012 | Journal of Gastroenterology and Hepatology2012，，3： | 1 |
| 17 | Study of Dongting Lake area variation and its influence on water level using MODIS data 显示文摘 | PENG DINGZHI GUO SHENGLIAN XIONG LIHUA | 2005 | Hydrological Sciences Journal2005，50，1： | 1 |
| 18 | A Two-Parameter Month- ly Water Balance Model and Its Application显示文摘 | Xiong Lihua Guo Shenglian | 1999 | Journal of Hydrology1999，216，12： | 1 |
| 19 | Deriving Reservoir Refill Operating Rules by Using the Proposed DPNS Model显示文摘 | Pan Liu Shenglian Guo Lihua Xiong Wei Li Honggang Zhang | 2006 | Water Resources Management2006，，3： | 1 |
| 20 | Metal chelate affinity to immobilize horseradish peroxidase on functionalized agarose/CNTs composites for the detection of catechol显示文摘The paper reports a novel amperometric biosensor for catechol based on immobilization of a highly sensitive horseradish peroxidase by affinity interactions on metal chelate-functionalized agarose/carbon nanotubes composites. Metal chelate affinity takes advantage of the affinity of Ni2+ ions to bind strongly and reversibly to histidine or cysteine tails found on the surface of the horseradish peroxidase. Thus, enzymes with such residues in their molecules can be easily attached to functionalized agarose/carbon nanotubes composites support containing a nickel chelate. Linear sweep voltammograms and amperometry are used to study the proposed electrochemical biosensor. Catechol is determined by direct reduction of biocatalytically liberated quinone species at -0.05 V (vs. SCE). The effect of pH, applied electrode potential and the concentration of H2O2 on the sensitivity of the biosensor has been investigated. The performance of the proposed biosensor is tested using four different phenolic compounds, showing very high sensitivity, in particular, the linearity of catechol is observed from 2.0 × 10-8 to 1.05 × 10-5 M with a detection limit of 5.0 × 10-9 M. | TU XinMan LUO ShengLian LUO XuBiao ZHAO YingJie FENG Li LI JingHong | 2011 | Science China Chemistry2011，54，8： | 1 |
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