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| 1 | Berberine sensitizes ovarian cancer cells to cisplatin through miR-21/PDCD4 axis显示文摘最近的研究证明了 microRNA-21 (miR-21 ) 贡献肿瘤抵抗到化疗。有趣地,我们发现了 berberine 能在几根癌症房间线禁止 miR-21 表示。在这研究,我们调查了 berberine 是否能调制卵巢的癌症房间的敏感到 cisplatin 并且探索机制。被孵化, berberine 与 cisplatin 结合了的 cisplatin 抵抗的 SKOV3 房间独自比 cisplatin 有 signicantly 更低的幸存组和提高的导致 cisplatin 的 apoptosis。Berberine 能在卵巢的癌症禁止 miR-21 表示和功能,由它的目标 PDCD4 的改进出现在卵巢的癌症的重要肿瘤 suppressor。结果建议 berberine 能经由在卵巢的癌症房间调整 miR-21/PDCD4 轴调制 cisplatin 的敏感。 | Shiguo Liu Yue Fang Huiling Shen Wenlin Xu Hao Li | 2013 | Acta Biochimica et Biophysica Sinica2013，45，9： | 9 |
| 2 | Study on nitrobenzene ratio in water-ice system under different conditions显示文摘A series of ice freezing-thawing experiments are performed under different nitro- benzene concentrations of 1.7, 8, 17, 170, and 1700 μg/L. A special flume, made of stainless steel and glass, is built to simulate the flowing water for the experiments. The ice frozen in cold room has similar crystal structure of natural ice, therefore the behaviors of nitrobenzene in the ice frozen in cold room is also believed to be similar to that in natural ice. The results of the experiments reveal that the freezing rate of ice decreases with the increase of nitrobenzene concentration in water, and that the nitrobenzene ratio in water-ice system becomes higher with the increase of freezing rate. In addition, the nitrobenzene in ice does not move and is only re- leased into water after melt. | LI ZhiJun WANG Xin LI QingShan XU ShiGuo XU XiangZhou BAI Yan | 2008 | Science China(Technological Sciences)2008，51，11： | 6 |
| 3 | Effects of Climatic Change on Evapotranspiration in Zhalong Wetland,Northeast China显示文摘Evapotranspiration (ET) process of plants is controlled by several factors. Besides the physiological factors of plants, height, density, LAI (leaf area index), etc., the change of meteorological factors, such as radiation, temperature, wind and precipitation, can influence ET process evidently, thus remodeling the spatial and temporal distribution of ET. In order to illuminate the effects of meteorological factors on wetland ET, the ET of Zhalong Wetland was calculated from 1961 to 2000, the statistical relationships (models) between ET and maximum temperature (Tmax), minimum temperature (Tmin), precipitation (P) and wind speed at 2m height (U2) were established, and the sensitivity analysis of the variables in the model was performed. The results show that Tmax and Tmin are two dominating factors that influence ET markedly, and the difference of rising rate between Tmax and Tmin determines the change trend of ET. With the climatic scenarios of four General Circulation Models (GCMs), the ET from 2001 to 2060 was predicted by the statistical model. Compared to the period of 1961-2000, the water consumption by ET will increase greatly in the future. According to the scenarios, the rise of Tmax (about 1.5℃ to 3.3℃) and Tmin (about 1.7℃ to 3.5℃) will cause an additional water con- sumption of 14.0%-17.8% for reed swamp. The ecological water demand in Zhalong Wetland will become more severe. | WANG Hao XU Shiguo SUN Leshi | 2006 | Chinese Geographical Science2006，16，3： | 5 |
| 4 | Microdisk lasers on an erbium-doped lithium-niobite chip显示文摘Lithium niobate on insulator(LNOI) provides a platform for the fundamental physics investigations and practical applications of integrated photonics. However, as an indispensable building block of integrated photonics, lasers are in short supply. In this paper, erbium-doped LNOI laser in the 1550-nm band was demonstrated in microdisk cavities with high quality factors fabricated in batches by UV exposure, inductively coupled plasma reactive ion etching, and chemomechanical polishing. The threshold and conversion efficiency of the erbium-doped LNOI microdisk laser were measured to be lower than 1 m W and 6.5×10^(-5)%, respectively. This work will benefit the development of integrated photonics based on LNOI. | Qiang Luo ZhenZhong Hao Chen Yang Ru Zhang DaHuai Zheng ShiGuo Liu HongDe Liu Fang Bo YongFa Kong GuoQuan Zhang JingJun Xu | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，3： | 4 |
| 5 | Numerical Study on the Effects of Equi-biaxial Residual Stress on Mechanical Properties of Nickel Film by Means of Nanoindentation显示文摘In this paper,mechanical properties of Nickel film under residual stress have been systematically examined by finite element method in nanoindentation.It was found that load-displacement curves shifted under elastic residual stress and residual stress exceeded the yield stress for fixed indentation depth.Indentation profiles changed monotonously with compressive and tensile stresses at peak force which determinates contact area observed directly by finite element modeling (FEM).The elastic residual stress has an effect slightly on the hardness but residual stress exceeded the yield stress shows a remarkable effect in nickel film.The hardness increased when residual stress exceeded the yield stress increased under tensile and compressive stress applied to specimen.The relationship between residual stress and hardness was linear.It was found that residual stresses didn't affect elastic modulus whether elastic residual stress or plastic stress was applied to specimen. | Lizeng Ling,Shiguo Long,Zengsheng Ma and Xu Liang Key Laboratory of Low Dimensional Materials and Application Technology of Ministry of Education,and Faculty of Materials,Optoelectronics and Physics,Xiangtan University,Xiangtan 411105,China | 2010 | Journal of Materials Science & Technology2010，26，11： | 3 |
| 6 | The real-time dynamic holographic display of LN:Bi,Mg crystals and defect-related electron mobility显示文摘Holographic display has attracted widespread interest because of its ability to show the complete information of the object and bring people an unprecedented sense of presence. The absence of ideal recording materials has hampered the realization of their commercial applications. Here we report that the response time of a bismuth and magnesium codoped lithium niobate(LN:Bi,Mg) crystal is shortened to 7.2 ms and a sensitivity as high as 646 cm/J. The crystal was used to demonstrate a real-time holographic display with a refresh rate of 60 Hz, as that of the popular high-definition television. Moreover, the first-principles calculations indicate that the electron mobility while Bi occupying Nb-site is significantly greater than that in Li-site, which directly induces the fast response of LN:Bi,Mg crystals when the concentration of Mg is above its doping threshold. | Shuolin Wang Yidong Shan Dahuai Zheng Shiguo Liu Fang Bo Hongde Liu Yongfa Kong Jingjun Xu | 2022 | Opto-Electronic Advances2022，5，12： | 2 |
| 7 | A Selective Fluorescent Sensor for Fast Detection of Hydrogen Sulfide in Red Wine显示文摘基于在 azido 组和氢硫化物之间的反应(H 2 S ) , BTN,在离开上荧光灯传感器被综合,它在 H 2 S,并且 5. | Qiwen Chen Panfei Xing Yongqian Xu Hongjuan Li Shiguo Sun | 2017 | Chinese Journal of Chemistry2017，35，4： | 2 |
| 8 | Naphthalimide-rhodamine based fluorescent probe for ratiometric sensing of cellular pH显示文摘The pH values of lysosomes in cancer cells is slightly lower than that in normal cells, which can be used to distinguish cancer cells from normal cells. According to this, a naphthalimide-rhodamine based fluorescent probe(hereafter referred to as RBN) with a pK_a of 4.20 was designed and synthesized for ratiometric sensing of cellular pH via fluorescence resonance energy transfer(FRET), which can respond to different pH precisely through ratiometric fluorescence intensity(Ⅰ_(577)/Ⅰ_(540)). RBN can be employed to distinguish cancer cells from normal cells on the basis of different fluorescent response, in particular, RBN showed excellent water solubility and low cell toxicity, all these are quite significant for potential application in cancer diagnose and therapy. | Jia Wen Pengyi Xia Ziming Zheng Yongqian Xu Hongjuan Li Fengyu Liu Shiguo Sun | 2017 | Chinese Chemical Letters2017，28，10： | 2 |
| 9 | Partitioning of vertical water loss in reed swamp wetlands:Theory,research and application显示文摘This paper proposes an on-site monitoring system for evaporation(Ew) and evapotranspiration(ET) in wetlands called the Compensation Evapotranspiration Observation System.Considering the characteristics of wetlands environment and emergent plants,the vertical flux of water loss in wetlands can be separated using the system based on compensation principle.A comparison research on water loss through ET in reed(Phragmites australis) stands between Zhalong wetland and Baiyangdian wetland was carried out in 2004-2009.In Baiyangdian wetland,the ET rates from three reed stands with different leaf area indexes were measured.The results show that annual ET in Zhalong wetland was 739-886 mm during study period.Comparatively,annual ET of the three reed stands in Baiyangdian wetland was 970-1117 mm,1261-1452 mm and 1759-2035 mm,respectively.The ET rates in Baiyangdian were stronger than in Zhalong because of the effects of geography and climate characteristics.Moreover,seasonal dynamic changes and influence factors of transpiration-acting factor from the two wetlands were also analyzed.It is indicated that the transpiration-acting factor can be affected by geographic location,aboveground biomass,plant growth and climate conditions. | XU ShiGuo MA Tao WANG Hao | 2011 | Science China(Technological Sciences)2011，54，11： | 1 |
| 10 | Estimating the regional evapotranspiration in Zhalong wetland with the Two-Source Energy Balance(TSEB) model and Landsat7 images显示文摘 | Yao Wei Hart Min Xu Shiguo | 2010 | Ecological Informatics2010，，5： | 1 |
| 11 | Modeling multisource multiuser water resources allocation显示文摘 | YAN Han XU Shiguo XU Xiangzhou | 2008 | Water Resources Management2008，22，7： | 1 |
| 12 | Assessment and prioritization of eco-revetment projects in urban rivers显示文摘 | Shi Ruihua Xu Shiguo Li Xuguang | 2009 | River Res Applic2009，25，8： | 1 |
| 13 | Prediction of chaotic time series based on the recurrent predic- tor neural network显示文摘 | Han Min Xi Jianhui Xu Shiguo | 2004 | IEEE Trans Signal Process- ing2004，52，12： | 1 |
| 14 | Characteristics and driving factors of marsh changes in Zhalong wetland of China显示文摘 | Han Min Sun Yannan Xu Shiguo | 2007 | Environment Monitoring Assessment2007，127，： | 1 |
| 15 | Characteristics and driving factors of marsh changes in Zhalong wetland of China显示文摘 | Min Han Yannan Sun Shiguo Xu | 2007 | Environment MonitoringAssessment2007，127，： | 1 |
| 16 | Characteristics and driving factors of marsh changes in Zhalong wetland of China显示文摘 | Han Min Sun Yannan Xu Shiguo | 2007 | Envi- ronment Monitoring Assessment2007，127，： | 1 |
| 17 | Acoustic Prediction and Risk Evaluation of Shallow Gas in Deep-Water Areas显示文摘Shallow gas is a potential risk in deep-water drilling that must not be ignored,as it may cause major safety problems,such as well kicks and blowouts.Thus,the pre-drilling prediction of shallow gas is important.For this reason,this paper conducted deep-water shallow gas acoustic simulation experiments based on the characteristics of deep-water shallow soil properties and the theory of sound wave speed propagation.The results indicate that the propagation speed of sound waves in shallow gas increases with an in-crease in pressure and decreases with increasing porosity.Pressure and sound wave speed are basically functions of the power expo-nent.Combined with the theory of sound wave propagation in a saturated medium,this paper establishes a multivariate functional relationship between sound wave speed and formation pressure and porosity.The numerical simulation method is adopted to simulate shal-low gas eruptions under different pressure conditions.Shallow gas pressure coefficients that fall within the ranges of 1.0-1.1,1.1-1.2,and exceeding 1.2 are defined as low-,medium-,and high-risk,respectively,based on actual operations.This risk assessment me-thod has been successfully applied to more than 20 deep-water wells in the South China Sea,with a prediction accuracy of over 90%. | YANG Jin WU Shiguo TONG Gang WANG Huanhuan GUO Yongbin ZHANG Weiguo ZHAO Shaowei SONG Yu YIN Qishuai XU Fei | 2022 | Journal of Ocean University of China2022，21，5： | 1 |
| 18 | Is sodium percarbonate a good deltamethrin choice in situ remediation of pollution?显示文摘 | Xu Zhang Baigang Ren Shangge Li Xiaodi Qu Huanhuan Yang Shiguo Xu Zongming Ren Qiang Kong Cheng Wang | 2017 | Frontiers of Environmental Science & Engineering2017，11，3： | 1 |
| 19 | Research on Neural Network Method in GPS Data Transformation显示文摘 | Min Han Xue Tian Shiguo Xu | 2004 | Lecture Notes in Computer Science2004，3174，： | 1 |
| 20 | Sequence determination of a non-sulfated glycosaminoglycan-like polysaccharide from melanin-free ink of the squid Ommastrephes bartrami by negative-ion electrospray tandem mass spectrometry and NMR spectroscopy显示文摘 | Shiguo Chen Jie Xu Changhu Xue Ping Dong Wenjing Sheng Guangli Yu Wengang Chai | 2008 | Glycoconjugate Journal2008，，5： | 1 |
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