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| 1 | Significance of dredging on sediment denitrification in Meiliang Bay,China:A year long simulation study显示文摘An experiment for studying the effects of sediment dredging on denitrification in sediments was carried out through a one-year incubation of undredged (control) and dredged cores in laboratory. Dredging the upper 30 cm of sediment can significantly affect physico-chemical characteristics of sediments. Less degradation of organic matter in the dredged sediments was found during the experiment. Denitrification rates in the sediments were estimated by the acetylene blockage technique, and ranged from 21.6 to 102.7 nmol N2/(g dry weight (dw)·hr) for the undredged sediment and from 6.9 to 26.9 nmol N2/(g dw·hr) for dredged sediments. The denitrification rates in the undredged sediments were markedly higher (p<0.05) than those in the dredged sediments throughout the incubation, with the exception of February 2006. The importance of various environmental factors on denitrification was assessed, which indicated that denitrification was regulated by temperature. Nitrate was probably the key factor limiting denitrification in both undredged and dredged sediments. Organic carbon played some role in determining the denitrification rates in the dredged sediments, but not in the undredged sediments. Sediment dredging influenced the mineralization of organic matter and denitrification in the sediment; and therefore changed the pattern of inherent cycling of nitrogen. | Jicheng Zhong Chengxin Fan Lu Zhang Edward Hall Shiming Ding Bao Li Guofeng Liu | 2010 | Journal of Environmental Sciences2010，22，1： | 40 |
| 2 | Speciation of organic phosphorus in a sediment profile of Lake Taihu I:Chemical forms and their transformation显示文摘Organic phosphorus(nonreactive P,NRP)is a major component of P in sediments,but information about its chemical forms and dynamic transformation is limited.The chemical forms and dynamic behaviors of NRP in a sediment profile from Lake Taihu,a freshwater and eutrophic lake in China,were investigated.Five forms of NRP in the sediments were extracted based on a chemical fractionation technique,including easily labile NRP(NaHCO3-NRP),reactive metal oxide-bound NRP(HCl-NRP),humic acid-associated NRP(NaOH-NRPHA),fulvic acid-associated NRP(NaOH-NRPFA)and residual NRP(Res-TP).There were notable transformations with increasing sediment depth from the labile NaHCO3-NRP and NaOH-NRP pools to the recalcitrant HCl-NRP and Res-TP pools,which caused the NRP to become increasingly recalcitrant as the early diagenetic processes proceeded.Further analyses showed that the relative changes in contents of organic matter and reactive Fe oxides in the sediment profile triggered a competition for binding NRP fractions and led to the transformation of NRP.The results highlighted the importance of abiotic processes in regulating the diagenesis of organic P and its stability in sediments. | Di Xu Shiming Ding Bin Li Xiuling Bai Chengxin Fan Chaosheng Zhang | 2013 | Journal of Environmental Sciences2013，25，4： | 7 |
| 3 | Research on cohesive sediment erosion by flow: An overview显示文摘Erosion of cohesive sediment by flow is a very complicated phenomenon occurring worldwide. Understanding and modeling of the erosion process are important for many issues such as the breaching of embankments, riverbank stability, siltation of harbors and navigation channels, service life of reservoirs, distribution of (heavy metal) pollutants and water quality problems. In the last few decades, numerous studies have been done on the erosion of cohesive sediment by flow. Nevertheless, the factors affecting the erosion resistance of cohesive sediment are still not fully understood and the knowledge of the physics of cohesive sediment erosion is in- adequate, as a result the mathematical modeling of this erosion is far from satis- factory. In this paper an overview of the studies on the erosion resistance, erosion threshold and the erosion rate of cohesive sediment by flow is presented. The outcomes achieved so far from the studies and the existing problems have been analyzed and summarized, based on which recommendations are proposed for future research. | YongHui Zhu JinYou Lu HongZhi Liao JiaSheng Wang BeiLin Fan ShiMing Yao | 2008 | Science China(Technological Sciences)2008，51，11： | 5 |
| 4 | Molybdenum isotopic composition as a tracer for low-medium temperature hydrothermal ore-forming systems:A case study on the Dajiangping pyrite deposit,western Guangdong Province,China显示文摘Little is known about the range or controls on the molybdenum isotopic composition of low-medium temperature hydrothermal ore-forming systems.We present molybdenum isotope data from 12 hydrothermal syndepositional silicalite and carbonaceous slate samples from the Dajiangping pyrite deposit in western Guangdong Province,South China.The δ 97/95Mo values from Orebody III range from ?0.02‰ to 0.29‰,with an average of 0.18‰.In contrast,the composition values from Orebody IV display a larger variation from ?0.70‰ to 0.62‰.However,the five samples from the main ore bed all show strong negative values.This indicates that the significant variation in molybdenum isotopic composition supports different hydrothermal ore-forming metallogenesis and a metallogenic environment between the two orebodies.Orebody III is likely to have been deposited from submarine exhalative hydrothermal fluids under a relatively strong reducing environment and Orebody IV may have also been influenced by hydrothermal superimposition in a more oxidized disequilibrium condition.In addition,the δ 97/95Mo values of Orebody IV are clearly negative,together with the values increasing stratigraphically upward in the ore beds,suggesting that the metallogenic environment of Orebody IV is different from the open oceanic systems.There might be dynamic fractionation in this restricted environment.Therefore,the molybdenum isotope can be used as an effective tracer for the ore-forming fluid and metallogenic environment. | SONG ShiMing HU Kai WEN HanJie ZHANG YuXu LI Kuang FAN HaiFeng | 2011 | Chinese Science Bulletin2011，56，21： | 4 |
| 5 | Speciation of organic phosphorus in a sediment profile of Lake Taihu Ⅱ.Molecular species and their depth attenuation显示文摘The understanding of organic phosphorus(P) dynamics in sediments requires information on their species at the molecular level,but such information in sediment profiles is scarce.A sediment profile was selected from a large eutrophic lake,Lake Taihu(China),and organic P species in the sediments were detected using solution phosphorus-31 nuclear magnetic resonance spectroscopy(31 P NMR) following extraction of the sediments with a mixture of 0.25 mol/L NaOH and 50 mmol/L EDTA(NaOH-EDTA) solution.The results showed that P in the NaOH-EDTA extracts was mainly composed of orthophosphate,orthophosphate monoesters,phospholipids,DNA,and pyrophosphate.Concentrations of the major organic P compound groups and pyrophosphate showed a decreasing trend with the increase of depth.Their half-life times varied from 3 to 27 years,following the order of orthophosphate monoesters > phospholipids DNA > pyrophosphate.Principal component analysis revealed that the detected organic P species had binding phases similar to those of humic acid-associated organic P(NaOH-NRP HA),a labile organic P pool that tends to transform to recalcitrant organic P pools as the early diagenetic processes proceed.This demonstrated that the depth attenuation of the organic P species could be partly attributed to their increasing immobilization by the sediment solids,while their degradation rates should be significantly lower than what were suggested in previous studies. | Shiming Ding Di Xu Xiuling Bai Shuchun Yao Chengxin Fan Chaosheng Zhang | 2013 | Journal of Environmental Sciences2013，25，5： | 3 |
| 6 | Viscosity and degradation controlled injectable hydrogel for esophageal endoscopic submucosal dissection显示文摘Endoscopic submucosal dissection(ESD)is a common procedure to treat early and precancerous gastrointestinal lesions.Via submucosal injection,a liquid cushion is created to lift and separate the lesion and malignant part from the muscular layer where the formed indispensable space is convenient for endoscopic incision.Saline is a most common submucosal injection liquid,but the formed liquid pad lasts only a short time,and thus repeated injections increase the potential risk of adverse events.Hydrogels with high osmotic pressure and high viscosity are used as an alternate;however,with some drawbacks such as tissue damage,excessive injection resistance,and high cost.Here,we reported a nature derived hydrogel of gelatin-oxidized alginate(G-OALG).Based on the rheological analysis and compare to commercial endoscopic mucosal resection(EMR)solution(0.25%hyaluronic acid,HA),a designed G-OALG hydrogel of desired concentration and composition showed higher performances in controllable gelation and injectability,higher viscosity and more stable structures.The G-OALG gel also showed lower propulsion resistance than 0.25%HA in the injection force assessment under standard endoscopic instruments,which eased the surgical operation.In addition,the G-OALG hydrogel showed good in vivo degradability biocompatibility.By comparing the results acquired via ESD to normal saline,the G-OALG shows great histocompatibility and excellent endoscopic injectability,and enables create a longer-lasting submucosal cushion.All the features have been confirmed in the living both pig and rat models.The G-OALG could be a promising submucosal injection agent for esophageal ESD. | Chaoqiang Fan Kaige Xu Yu Huang Shuang Liu Tongchuan Wang Wei Wang Weichao Hu Lu Liu Malcolm Xing Shiming Yang | 2021 | Bioactive Materials2021，6，4： | 3 |
| 7 | Programmed cell death 4 (PDCD4) mediates the sensitivity of gastric cancer cells to TRAIL-induced apoptosis by down-regulation of FLIP expression显示文摘 | Weiqiang Wang Jingjing Zhao Hongbin Wang Yonggang Sun Zhihong Peng Gang Zhou Lilin Fan Xingwei Wang Shiming Yang Rongquan Wang Dianchun Fang | 2010 | Experimental Cell Research2010，，15： | 2 |
| 8 | A study on the performance of a geothermal heat exchanger under coupled heat conduction and groundwater advection显示文摘 | Rui Fan Yiqiang Jiang Yang Yao Deng Shiming Zuiliang Ma | 2007 | Energy2007，，11： | 1 |
| 9 | Hydrogen-rich gas from catalytic steam gasification of municipal solid waste (MSW): influence of catalyst and temperature on yield and product composition 显示文摘 | He Maoyun Hu Zhiquan Xiao Bo Li Jianfen Guo Xianjun Luo Siyi Yang Fan Feng Yu Yang Guangjun Liu Shiming | 2009 | International Journal of Hydrogen Energy2009，34，1： | 1 |
| 10 | Caution Needed in Pretreatment of Sediments for Refining Phosphorus-31 Nuclear Magnetic Resonance Analysis: Results from a Comprehensive Assessment of Pretreatment with Ethylenediaminetetraacetic Acid显示文摘 | Ding ShiMing Bai Xiuling Fan Chengxin Zhang Lu | 2010 | EN2010，，5： | 1 |
| 11 | Syngas production from pyrolysis of municipal solid waste (MSW) with dolomite as downstream catalysts显示文摘 | Maoyun He Bo Xiao Shiming Liu Zhiquan Hu Xianjun Guo Siyi Luo Fan Yang | 2010 | Journal of Analytical and Applied Pyrolysis2010，，2： | 1 |
| 12 | Volitinib, a potent and highly selective c-Met inhibitor, effectively blocks c-Met signaling and growth in c-MET amplified gastric cancer patient-derived tumor xenograft models显示文摘 | Paul R. Gavine Yongxin Ren Lu Han Jing Lv Shiming Fan Wei Zhang Wen Xu Yuan Jie Liu Tianwei Zhang Haihua Fu Yongjuan Yu Huiying Wang Shirlian Xu Feng Zhou Xinying Su XiaoLu Yin Liang Xie Linfang Wang Weiguo Qing Longxian Jiao Weiguo Su Q. May Wang | 2014 | Molecular Oncology2014，，： | 1 |
| 13 | Using hexadecyl trimethyl ammonium bromide (CTAB) modified clays to clean the Microcystis aeruginosa blooms in Lake Taihu, China显示文摘 | Guofeng Liu Chengxin Fan Jicheng Zhong Lu Zhang Shiming Ding Shaohua Yan Shiqun Han | 2010 | Harmful Algae2010，，4： | 1 |
| 14 | Low bandgap n-conjugated copolymers based on fused thiophenes and benzothiadiazole: Synthesis and structure-property relationship study 显示文摘 | Zhang Shiming Guo Yunlong Fan Haijun | 2009 | Journal of Polymer Scienee Part A: Polymer Chemistry2009，47，20： | 1 |
| 15 | LDL receptor-related protein 1 (LRP1),a novel target for opening the blood-labyrinth barrier(BLB)显示文摘Inner ear disorders are a cluster of diseases that cause hearing loss in more than 1.5 billion people worldwide.However,the presence of the blood-labyrinth barrier(BLB)on the surface of the inner ear capillaries greatly hinders the effectiveness of systemic drugs for prevention and intervention due to the low permeability,which restricts the entry of most drug compounds from the bloodstream into the inner ear tissue.Here,we report the finding of a novel receptor,low-density lipoprotein receptor-related protein 1(LRP1),that is expressed on the BLB,as a potential target for shuttling therapeutics across this barrier.As a proof-ofconcept,we developed an LRP1-binding peptide,IETP2,and covalently conjugated a series of model small-molecule compounds to it,including potential drugs and imaging agents.All compounds were successfully delivered into the inner ear and inner ear lymph,indicating that targeting the receptor LRP1 is a promising strategy to enhance the permeability of the BLB.The discovery of the receptor LRP1 will illuminate developing strategies for crossing the BLB and for improving systemic drug delivery for inner ear disorders. | Xi Shi Zihao Wang Wei Ren Long Chen Cong Xu Menghua Li Shiyong Fan Yuru Xu Mengbing Chen Fanjun Zheng Wenyuan Zhang Xinbo Zhou Yue Zhang Shiwei Qiu Liyuan Wu Peng Zhou Xinze Lv Tianyu Cui Yuehua Qiao Hui Zhao Weiwei Guo Wei Chen Song Li Wu Zhong Jian Lin Shiming Yang | 2022 | Signal Transduction and Targeted Therapy2022，7，7： | 0 |
| 16 | Total synthesis and stereochemistry establishmentof tumescenamide A显示文摘Tumescenamide A (1), isolated from Streptomyces tumescens YM23-20, consists of a cyclic depsipeptideand a side-chain 2,4-dimethylheptanoate (Dmh). Herein, we report the first total synthesis of tumescenamide A (1) and establish its stereochemistry. The configuration of Dmh is 2S,4S and, notably, the configuration of Val is revised as D. In addition, a mild and practical method for the β-elimination of derivatives ofserine and threonine by using nano-K_(2)CO_(3) as a base was established. A highly stereoselective synthesis ofthe Dmh substructure was also developed. | Hong Xue Shiming Fan Jingzhe Xu Shouxin Liu | 2022 | Organic Chemistry Frontiers2022，9，6： | 0 |
| 17 | Structure and strain tunings of topological anomalous Hall effect in cubic noncollinear antiferromagnet Mn3Pt epitaxial films显示文摘Antiferromagnets(AFMs)with chiral noncollinear spin structure have attracted great attention in recent years.However,the existing research has mainly focused on hexagonal chiral AFMs,such as Mn3Sn,Mn3Ga,Mn3Ge with low crystalline symmetry.Here,we present our systematical study for the face-centered cubic noncollinear antiferromagnetic Mn3Pt.By varying the alloy composition(x),we have successfully fabricated antiferromagnetic Mn1-xPtx epitaxial films on MgO substrates and have observed a crystalline structure transition from L10 MnPt to L12 Mn3Pt.The Mn3Pt exhibits a large anomalous Hall effect,which is in the same order of magnitude as those of ferromagnetic materials.Moreover,a large thickness-evolved strain effect is revealed in Mn3Pt films by X-ray diffraction(XRD)analysis based on the Scherrer method.Our work explores Mn3Pt as a promising candidate for topological antiferromagnetic spintronics. | Ning An Meng Tang Shuai Hu HuangLin Yang WeiJia Fan ShiMing Zhou XuePeng Qiu | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，9： | 0 |
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