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| 1 | Progress in China's Unconventional Oil & Gas Exploration and Development and Theoretical Technologies显示文摘The new century has witnessed a strategic breakthrough in unconventional oil & gas.Hydrocarbon accumulated in micro-/nano-scale pore throat shale systems has become an important domain that could replace current oil & gas resources.Unconventional oil & gas plays an increasingly important role in our energy demand.Tight gas,CBM,heavy oil and asphaltic sand have served as a key domain of exploration & development,with tight oil becoming a 'bright spot' domain and shale gas becoming a 'hotspot' domain.China has made great breakthroughs in unconventional oil & gas resources,such as tight gas,shale gas,tight oil and CBM,and great progress in oil shale,gas hydrate,heavy oil and oil sand.China has an estimated(223-263)×10~8t of unconventional oil resources and(890-1260)×l0^(12)m^3 of gas resources.China has made a breakthrough for progress in unconventional oil & gas study.New progress achieved in fine-grained sedimentary studies related to continental open lacustrine basin large-scale shallow-water delta sand bodies,lacustrine basin central sandy clastic flow sediments and marine-continental fine-grained sediments provide a theoretical basis for the formation and distribution of basin central reservoir bodies.Great breakthroughs have been made in unconventional reservoir geology in respect of research methodology & technology,multi-scale data merging and physical simulation of formation conditions.Overall characterization of unconventional reservoirs via multi-method and multi-scale becomes increasingly popular and facilitates the rapid development of unconventional oil & gas geological theory,method and technology.The formation of innovative,continuous hydrocarbon accumulation theory,the establishment of the framework of the unconventional oil & gas geological theory system,and the determination of the implications,geological feature,formation mechanism,distribution rule and core technology of unconventional oil& gas geological study lays a theoretical foundation for extensive unconventional oil & gas exploration and development.Theories and technologies of unconventional oil & gas exploration and development developed rapidly,including some key evaluation techniques such as 'sweet spot zone' integrated evaluation and a six-property evaluation technique that uses hydrocarbon source,lithology,physical property,brittleness,hydrocarbon potential and stress anisotropy,and some key development &engineering technologies including micro-seismic monitoring,horizontal drilling & completion and 'factory-like' operation pattern, 'man-made reservoir' development,which have facilitated the innovative development of unconventional oil & gas.These breakthroughs define a new understanding in four aspects:①theoretical innovation;② key technologies;③ complete market mechanism and national policy support;and ④ well-developed ground infrastructure,which are significant for prolonging the life cycle of petroleum industry,accelerating the upgrade and development of theories and technologies and altering the global traditional energy structure. | ZOU Caineng YANG Zhi ZHU Rukai ZHANG Guosheng HOU Lianhua WU Songtao TAO Shizhen YUAN Xuanjun DONG Dazhong WANG Yuman WANG Lan HUANG Jinliang WANG Shufang | 2015 | Acta Geologica Sinica(English Edition)2015，89，3： | 27 |
| 2 | Effects of alfalfa coverage on runoff,erosion and hydraulic characteristics of overland flow on loess slope plots显示文摘An evaluation of the interactions between vegetation,overland and soil erosion can provide valuable insight for the conservation of soil and water.An experiment was conducted to study water infiltration,runoff generation process,rate of sediment erosion,and hydrodynamic characteristics of overland flow from a sloping hillside with different draw-off discharges from alfalfa and control plots with 20°slope.The effect of alfalfa on runoff and sediment transport reduction was quantitatively analyzed.Alfalfa was discussed for its ability to reduce the overland flow scouring force or change the runoff movement.Compared to the bare-soil plots,alfalfa plots generated a 1.77 times increase in infiltration rate.Furthermore,the down-slope water infiltration rate for the bare soil plots was higher than in the up-slope,while the opposite was found in the alfalfa plots.In addition,alfalfa had a significant effect on runoff and sediment yield.In comparison to the control,the runoff coefficient and sediment transportation rate decreased by 28.3%and 78.4%in the grass slope,respectively.The runoff generated from the alfalfa and bare-soil plots had similar trends with an initial increase and subsequent leveling to a steady-state rate.The transport of sediment reduced with time as a consequence of the depletion of loose surface materials.The maximum sediment concentration was recorded within the first few minutes of each event.The alfalfa plots had subcritical flow while the baresoil plots had supercritical flow,which indicate that the capability of the alfalfa slope for resisting soil erosion and sediment movement was greater than for bare soil plots.Moreover,the flow resistance coefficient and roughness coefficient for the alfalfa plots were both higher than for the bare-soil plots,which indicate that overland flow in alfalfa plots had retarded and was blocked,and the flow energy along the runoff path had gradually dissipated.Finally,the ability to erode and transport sediment had decreased. | Shufang WU Pute WU Hao FENG G.P.Merkley | 2011 | Frontiers of Environmental Science & Engineering2011，5，1： | 11 |
| 3 | Methods for Shale Gas Play Assessment: A Comparison between Silurian Longmaxi Shale and Mississippian Barnett Shale显示文摘Based on field work, organic geochemical analyses and experimental testing, a six-property assessment method for shale gas is proposed. These six properties include organic matter properies, lithofacies, petrophysical properties, gas content, brittleness and local stress field. Due to the features of continuous distribution over a large area and low resource abundance in shale plays, a sweet spot should have these following properties:(a) TOC>2%;(b) brittle minerals content(>40%) and clay minerals(<30%);(c) Ro(>1.1%);(d) porosity(>2%) and permeability(>0.000 1 m D), and(e) effective thickness(30–50 m). Applying these criteria in the Sichuan Basin, the Silurian Longmaxi shale consists of four prospecting sweet spots, including blocks of Changning, Weiyuan, Zhaotong and Fushun-Yongchuan. Although these four blocks have some similarities, different features were usually observed. After comprehensive analyses using the six-property assessment method, the Fushun-Yongan Block ranks the most favorable sweet spot, followed by the Weiyuan Block. For the other two blocks, the Changning Block is better than the Zhaotong Block. By comparing with the Mississippian Barnett shale, characteristics that are crucial for a high-yielding in the Sichuan Basin include a high content of organic matter(TOC>2.5%), a moderate thermal maturity(Ro=0.4%–2%), a high content of brittle minerals(quartz: 30%–45%), a high gas content(>2.5 m3?t-1), and types I and II1 kerogen. | Songqi Pan Caineng Zou Zhi Yang Dazhong Dong Yuman Wang Shufang Wang Songtao Wu Jinliang Huang Qun Liu Dule Wang Ziyuan Wang | 2015 | Journal of Earth Science2015，26，2： | 10 |
| 4 | Shale Gas Formation and Occurrence in China: An Overview of the Current Status and Future Potential显示文摘Shale gas is one of the most promising unconventional resources both in China and abroad. It is known as a form of self-contained source-reservoir system with large and continuous dimensions. Through years of considerable exploration efforts, China has identified three large shale gas fields in the Fuling, Changning and Weiyuan areas of the Sichuan Basin, and has announced more than 540 billion m^3 of proven shale gas reserves in marine shale systems. The geological theories for shale gas development have progressed rapidly in China as well. For example, the new depositional patterns have been introduced for deciphering the paleogeography and sedimentary systems of the Wufeng shale and Longmaxi shale in the Sichuan Basin. The shale gas storage mechanism has been widely accepted as differing from conventional natural gas in that it is adsorbed on organic matter or a mineral surface or occurs as free gas trapped in pores and fractures of the shale. Significant advances in the techniques of microstructural characterization have provided new insights on how gas molecules are stored in micro- and nano-scale porous shales. Furthermore, newly-developed concepts and practices in the petroleum industry, such as hydraulic fracturing, microseismic monitoring and multiwell horizontal drilling, have made the production of this unevenly distributed but promising unconventional natural gas a reality. China has 10–36 trillion m^3 of promising shale gas among the world's whole predicted technically recoverable reserves of 206.6 trillion m^3. China is on the way to achieving its goal of an annual yield of 30–50 billion m^3 by launching more trials within shale gas projects. | ZOU Caineng YANG Zhi PAN Songqi CHEN Yanyan LIN Senhu HUANG Jinliang WU Songtao DONG Dazhong WANG Shufang LIANG Feng SUN Shasha HUANG Yong WENG Dingwei | 2016 | Acta Geologica Sinica(English Edition)2016，90，4： | 9 |
| 5 | Different manual manipulations and electrical parameters exert different therapeutic effects of acupuncture显示文摘Acupuncture is an important component part of Traditional Chinese Medicine(TCM). The therapeutic effects may be influenced by a variety of factors.Stimulation quantity is one of the factors for achieving good therapeutic effects in acupuncture practice. With the development of science and technology, besides the influence of manual manipulations, the parameters adopted for electroacupuncture have become the benchmark of stimulation quantity. This study, by referring to the related literatures, is designed to explore the influence of manual manipulations and electrical parameters on therapeutic effects of acupuncture. The results from the present study show that different manualmanipulations and electrical parameters may exert different therapeutic effects of acupuncture, which are closely related to the characteristics of diseases.Different manual manipulations and electrical parameters should be adopted according to syndrome differentiation of TCM. This is very important in acupuncture treatment. | Zheng Yu Lu Luo Yu Li Qiaofeng Wu Shufang Deng Shouying Lian Fanrong Liang | 2014 | Journal of Traditional Chinese Medicine2014，34，6： | 5 |
| 6 | Cholesterol-tuned liposomal membrane rigidity directs tumor penetration and anti-tumor effect显示文摘Recently, liposomes have been widely used in cancer therapeutics, but their anti-tumor effects are suboptimal due to limited tumor penetration. To solve this problem, researchers have made significant efforts to optimize liposomal diameters and potentials, but little attention has been paid to liposomal membrane rigidity. Herein, we sought to demonstrate the effects of cholesterol-tuned liposomal membrane rigidity on tumor penetration and anti-tumor effects. In this study, liposomes composed of hydrogenated soybean phospholipids(HSPC), 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000](DSPE-PEG2000) and different concentrations of cholesterol were prepared. It was revealed that liposomal membrane rigidity decreased with the addition of cholesterol. Moderate cholesterol content conferred excellent diffusivity to liposomes in simulated diffusion medium, while excessive cholesterol limited the diffusion process. We concluded that the differences of the diffusion rates likely stemmed from the alterations in liposomal membrane rigidity, with moderate rigidity leading to improved diffusion. Next, the in vitro tumor penetration and the in vivo anti-tumor effects were analyzed. The results showed that liposomes with moderate rigidity gained excellent tumor penetration and enhanced anti-tumor effects. These findings illustrate a feasible and effective way to improve tumor penetration and therapeutic efficacy of liposomes by changing the cholesterol content, and highlight the importance of liposomal membrane rigidity. | Hangyi Wu Miaorong Yu Yunqiu Miao Shufang He Zhuo Dai Wenyi Song Yuan Liu Sha Song Ejaj Ahmad Dongkai Wang Yong Gan | 2019 | Acta Pharmaceutica Sinica B2019，9，4： | 5 |
| 7 | Sparse grid-based polynomial chaos expansion for aerodynamics of an airfoil with uncertainties显示文摘The uncertainties can generate fluctuations with aerodynamic characteristics. Uncertainty Quantification(UQ) is applied to compute its impact on the aerodynamic characteristics.In addition, the contribution of each uncertainty to aerodynamic characteristics should be computed by uncertainty sensitivity analysis. Non-Intrusive Polynomial Chaos(NIPC) has been successfully applied to uncertainty quantification and uncertainty sensitivity analysis. However, the non-intrusive polynomial chaos method becomes inefficient as the number of random variables adopted to describe uncertainties increases. This deficiency becomes significant in stochastic aerodynamic analysis considering the geometric uncertainty because the description of geometric uncertainty generally needs many parameters. To solve the deficiency, a Sparse Grid-based Polynomial Chaos(SGPC) expansion is used to do uncertainty quantification and sensitivity analysis for stochastic aerodynamic analysis considering geometric and operational uncertainties. It is proved that the method is more efficient than non-intrusive polynomial chaos and Monte Carlo Simulation(MSC) method for the stochastic aerodynamic analysis. By uncertainty quantification, it can be learnt that the flow characteristics of shock wave and boundary layer separation are sensitive to the geometric uncertainty in transonic region. The uncertainty sensitivity analysis reveals the individual and coupled effects among the uncertainty parameters. | Xiaojing WU Weiwei ZHANG Shufang SONG Zhengyin YE | 2018 | Chinese Journal of Aeronautics2018，31，5： | 5 |
| 8 | Methylenetetrahydrofolate Reductase Gene Polymorphism C677T is Associated with Increased Risk of Coronary Heart Disease in Chinese Type 2 Diabetic Patients显示文摘Objective Chronic cardiovascular diseases induced by long-term poor blood glucose control are the main cause of death in patients with type 2 diabetes mellitus(T2DM).Previous researches report that methylenetetrahydrofolate reductase gene(MTHFR)polymorphisms might influence the occurrence of coronary heart disease(CHD)in T2DM patients.The purpose of this study was to evaluate whether MTHFR C677T and A1298C mutations are associated with the risk of CHD inT2DM patients.Methods A total of 197 subjects with T2DM were studied,of which 95 patients with CHD.The genotypes of MTHFR C677T and A1298C were analyzed by using dideoxy chain-termination method,and compared between patients with CHD and those without CHD.Results We found that the frequency of the 677T allele was significantly higher in T2DM patients with CHD than those without CHD(P=0.011).However,there was no significant difference in any of the examined haplotypes between T2DM patients with and without CHD.Furthermore,the 677T allele was associated with a higher risk of CHD development in diabetic patients with lower homocysteine(Hey)levels(≤15μmol/L)(P=0.006),while no effect of MTHFR gene polymorphism on the incidence of CHD was found in patients with higher Hey levels(>15 μmol/L)(P=0.491).Conclusion The MTHFR C677T gene polymorphism is associated with the risk of CHD of diabetic patients and could be used as an effective marker for CHD in Chinese diabetic populations with normal Hey levels. | Kunrong Wu Shufang Zhang Ziwan Guan Xiaoli Li Rui Li Ying Yin Yan Li | 2021 | Chinese Medical Sciences Journal2021，36，2： | 4 |
| 9 | Transcriptomics and metabolomics analyses provide insights into postharvest ripening and senescence of tomato fruit under low temperature显示文摘Tomato is one of the most important vegetable crops in the world and is a model plant used to study the ripening of climacteric fleshy fruit.During the ripening process of tomato fruit,flavor and aroma metabolites,color,texture and plant hormones undergo significant changes.However,low temperatures delayed the ripening process of tomato fruit,inhibiting flavor compounds and ethylene production.Metabolomics and transcriptomics analyses of tomato fruit stored under low temperature(LT,5°C)and room temperature(RT,25°C)were carried out to investigate the effects of storage temperature on the physiological changes in tomato fruit after harvest.The results of transcriptomics changes revealed that the differentially expressed genes(DEGs)involved in tomato fruit ripening,including several kinds of transcription factors(TFs)(TCP,WRKY,MYB and bZIP),enzymes involved in cell wall metabolism[beta-galactosidase(β-GAL),pectinesterase(PE)and pectate lyase(PL),cellulose and cellulose synthase(CESA)],enzymes associated with fruit flavor and aroma[acetyltransferase(AT),malic enzyme(ME),lipoxygenase(LOX),aldehyde dehydrogenase(ALDH),alcohol dehydrogenase(ADH)and hexokinase(HK)],genes associated with heat stress protein 70 and genes involved in the production of plant hormones such as Ethylene responsive factor 1(ERF1),Auxin/indoleacetic acids protein(AUX/IAA),gibberellin regulated protein.Based on the above results,we constructed a regulatory network model of the effects of different temperatures during the fruit ripening process.According to the analysis of the metabolomics results,it was found that the contents of many metabolites in tomato fruit were greatly affected by storage temperature,including,organic acids(L-tartaric acid,a-hydroxyisobutyric acid and 4-acetamidobutyric acid),sugars(melezitose,beta-Dlactose,D-sedoheptulose 7-phosphate,2-deoxyribose 1-phosphate and raffinose)and phenols(coniferin,curcumin and feruloylputrescine).This study revealed the effects of storage temperature on postharvest tomato fruit and provided a basis for further understanding of the molecular biology and biochemistry of fruit ripening. | Chunmei Bai Caie Wu Lili Ma Anzhen Fu Yanyan Zheng Jiawei Han Changbao Li Shuzhi Yuan Shufang Zheng Lipu Gao Xinhua Zhang Qing Wang Demei Meng Jinhua Zuo | 2023 | Horticultural Plant Journal2023，9，1： | 3 |
| 10 | The clinical and genetic characteristics in children with mitochondrial disease in China显示文摘Mitochondrial disease was a clinically and genetically heterogeneous group of diseases, thus the diagnosis was very difficult to clinicians. Our objective was to analyze clinical and genetic characteristics of children with mitochondrial disease in China. We tested 141 candidate patients who have been suspected of mitochondrial disorders by using targeted next-generation sequencing(NGS), and summarized the clinical and genetic data of gene confirmed cases from Neurology Department, Beijing Children's Hospital, Capital Medical University from October 2012 to January 2015. In our study, 40 cases of gene confirmed mitochondrial disease including eight kinds of mitochondrial disease, among which Leigh syndrome was identified to be the most common type, followed by mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes(MELAS). The age-of-onset varies among mitochondrial disease, but early onset was common. All of 40 cases were gene confirmed, among which 25 cases(62.5%)with mitochondrial DNA(mtDNA) mutation, and 15 cases(37.5%) with nuclear DNA(nDNA) mutation. M.3243A>G(n=7)accounts for a large proportion of mtDNA mutation. The nDNA mutations include SURF1(n=7),PDHA1(n=2),and NDUFV1,NDUFAF6, SUCLA2, SUCLG1, RRM2 B, and C12orf65, respectively. | Fang Fang Zhimei Liu Hezhi Fang Jian Wu Danmin Shen Suzhen Sun Changhong Ding Tongli Han Yun Wu Junlan Lv Lei Yang Shufang Li Jianxin Lv Ying Shen | 2017 | Science China(Life Sciences)2017，60，7： | 2 |
| 11 | The Main Progress of Perovskite Solar Cells in 2020-2021显示文摘Perovskite solar cells(PSCs)emerging as a promising photovoltaic technology with high efficiency and low manufacturing cost have attracted the attention from all over the world.Both the efficiency and stability of PSCs have increased steadily in recent years,and the research on reducing lead leakage and developing eco-friendly lead-free perovskites pushes forward the commercialization of PSCs step by step.This review summarizes the main progress of PSCs in 2020 and 2021 from the aspects of efficiency,stability,perovskite-based tandem devices,and lead-free PSCs.Moreover,a brief discussion on the development of PSC modules and its challenges toward practical application is provided. | Tianhao Wu Zhenzhen Qin Yanbo Wang Yongzhen Wu Wei Chen Shufang Zhang Molang Cai Songyuan Dai Jing Zhang Jian Liu Zhongmin Zhou Xiao Liu Hiroshi Segawa Hairen Tan Qunwei Tang Junfeng Fang Yaowen Li Liming Ding Zhijun Ning Yabing Qi Yiqiang Zhang Liyuan Han | 2021 | Nano-Micro Letters2021，13，10： | 2 |
| 12 | Anomaly detection in smart grid based on encoder-decoder framework with recurrent neural network显示文摘Anomaly detection in smart grid is critical to enhance the reliability of power systems.Excessive manpower has to be involved in analyzing the measurement data collected from intelligent motoring devices while performance of anomaly detection is still not satisfactory.This is mainly because the inherent spatio-temporality and multi-dimensionality of the measurement data cannot be easily captured.In this paper,we propose an anomaly detection model based on encoder-decoder framework with recurrent neural network(RNN).In the model,an input time series is reconstructed and an anomaly can be detected by an unexpected high reconstruction error.Both Manhattan distance and the edit distance are used to evaluate the difference between an input time series and its reconstructed one.Finally,we validate the proposed model by using power demand data from University of California,Riverside(UCR) time series classification archive and IEEE 39 bus system simulation data.Results from the analysis demonstrate that the proposed encoder-decoder framework is able to successfully capture anomalies with a precision higher than 95%. | Zheng Fengming Li Shufang Guo Zhimin Wu Bo Tian Shiming Pan Mingming | 2017 | The Journal of China Universities of Posts and Telecommunications2017，24，6： | 2 |
| 13 | Rapid design platform for mechanical products based on CBR显示文摘 | Wu Shufang Wang Zongyan pang longliang | 2010 | Advanced Materials Research2010，102，104： | 1 |
| 14 | Research of variant design method for product-level 显示文摘 | Wang Zongyan Wu Shufang Pang Longliang | 2010 | Advanced Materials Research-Digital Design and Manufacturing Technology2010，，5： | 1 |
| 15 | Rapid design platform for mechanical products based on CBR显示文摘 | WU Shufang WANG Zongyan | 2010 | Advanced Materials Research2010，102，： | 1 |
| 16 | Fast and Reliable Mouse Picking Using Graphics Hardware显示文摘 | Hanli Zhao Xiaogang Jin Jianbing Shen Shufang Lu Zhongke Wu | 2009 | International Journal of Computer Games Technology2009，，： | 1 |
| 17 | Rapid design platform for mechanical products based on CBR 显示文摘 | Wu Shufang Wang Zongyan | 2010 | Advanced Materials Research2010，102，104： | 1 |
| 18 | Topic Tracking with Bayes- ian Belief Network显示文摘 | Jianmin Xu Shufang Wu Yu hong | 2014 | Optik2014，125，9： | 1 |
| 19 | EXPONENTIAL TIKHONOV REGULARIZATION METHOD FOR SOLVING AN INVERSE SOURCE PROBLEM OF TIME FRACTIONAL DIFFUSION EQUATION显示文摘In this paper,we mainly study an inverse source problem of time fractional diffusion equation in a bounded domain with an over-specified terminal condition at a fixed time.A novel regularization method,which we call the exponential Tikhonov regularization method with a parameter γ,is proposed to solve the inverse source problem,and the corresponding convergence analysis is given under a-priori and a-posteriori regularization parameter choice rules.Whenγis less than or equal to zero,the optimal convergence rate can be achieved and it is independent of the value of γ.However,when γ is greater than zero,the optimal convergence rate depends on the value of γ which is related to the regularity of the unknown source.Finally,numerical experiments are conducted for showing the effectiveness of the proposed exponential regularization method. | Zewen Wang Shufang Qiu Shuang Yu Bin Wu Wen Zhang | 2023 | Journal of Computational Mathematics2023，41，2： | 1 |
| 20 | Incorporation ofγ-aminobutyric acid and cesium cations to formamidinium lead halide perovskites for highly efficient solar cells显示文摘The stability issue has become one of the main challenges for the commercialization of perovskite solar cells(PSCs).Formamidinium(FA)-based perovskites have shown great promise owing to their improved thermal and moisture stability.However,these perovskites are suffering from phase transition and separation.Here,a method of incorporating of γ-aminobutyric acid(GABA) and cesium cations into FAPbl_(3) is developed to improve the phase stability.It is demonstrated that the crystallinity of α-FAPbl_(3) phase is greatly improved and the phase transition temperature is significantly dropped.The resultant solar cell therefore obtains a champion power conversion efficiency(PCE) of 23.71%,which is one of the highest efficiencies for methylammonium-free PSCs.Furthermore,it shows an impressively enhanced stability under illumination,exhibiting the great potential of FA-based perovskites for efficient and stable solar cells. | Yanqiang Hu Yansu Shan Zhaolei Yu Haojie Sui Ting Qiu Shufang Zhang Wei Ruan Qinfeng Xu Mengmeng Jiao Dehua Wang Yunyi Wu Chuanlu Yang Feng Xu | 2022 | Journal of Energy Chemistry2022，31，1： | 1 |
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