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| 1 | Endoscopic ultrasound and magnetic resonance imaging for re-staging rectal cancer after radiotherapy显示文摘AIM:To compare the sensitivity and specificity of two imaging techniques,endoscopic ultrasound (EUS) and magnetic resonance imaging (MRI),in patients with rectal cancer after neoadjuvant chemoradiation therapy. And we compared EUS and MRI data with histological fi ndings from surgical specimens. METHODS:Thirty-nine consecutive patients (51.3% Male; mean age:68.2 ± 8.9 years) with histologically confirmed distal rectal cancer were examined for staging. All patients underwent EUS and MRI imaging before and after neoadjuvant chemoradiation therapy. RESULTS:After neoadjuvant chemoradiation,EUS and MRI correctly classified 46% (18/39) and 44% (17/39) of patients,respectively,in line with their histological T stage (P > 0.05). These proportions were higher for both techniques when nodal involvement was considered:69% (27/39) and 62% (24/39). When patients were sorted into T and N subgroups,the diagnostic accuracy of EUS was better than MRI for patients withT0-T2 (44% vs 33%,P > 0.05) and N0 disease (87% vs 52%,P = 0.013). However,MRI was more accurate than EUS in T and N staging for patients with more advanced disease after radiotherapy,though these differences did not reach statistical significance. CONCLUSION:EUS and MRI are accurate imaging techniques for staging rectal cancer. However,after neoadjuvant RT-CT,the role of both methods in the assessment of residual rectal tumors remains uncertain. | Gianni Mezzi Paolo Giorgio Arcidiacono Silvia Carrara Francesco Perri Maria Chiara Petrone Francesco De Cobelli Simone Gusmini Carlo Staudacher Alessandro Del Maschio Pier Alberto Testoni | 2009 | World Journal of Gastroenterology2009，15，44： | 9 |
| 2 | Significance of signet ring cells in high-grade mucinous adenocarcinoma of the peritoneum from appendiceal origin显示文摘 | S. Joseph Sirintrapun Aaron U. Blackham Greg Russell Konstantinos Votanopoulos John H. Stewart Perry Shen Edward A. Levine Kim R. Geisinger Simon Bergman | 2014 | Human Pathology2014，，： | 1 |
| 3 | Interrelationship and clinical significance of increased resistance in the uterine arteries in patients with hypertension or preeclanpsia or both 显示文摘 | Kafinas AD Perry M Simon NV | 1992 | Am j Obstet Gynecol1992，166，： | 1 |
| 4 | THE ROLE OF ROOT EXUDATES IN RHIZOSPHERE INTERACTIONS WITH PLANTS AND OTHER ORGANISMS显示文摘 | Harsh P. Bais Tiffany L. Weir Laura G. Perry Simon Gilroy Jorge M. Vivanco | 2006 | Annual Review of Plant Biology2006，，： | 1 |
| 5 | Interaction of ochratoxin A with human serum albumin, preferential binding of the dianion and pH effects显示文摘 | I1' ichev Y V Perry J L Simon J D | 2002 | J Phys Chem B2002，106，2： | 1 |
| 6 | Interaction of ochratoxin A with human serum albumin:preferential binding of the dianion and pH effects显示文摘 | LL'ICHEV Y V PERRY J L SIMON J D | 2002 | J Phys Chem B2002，106，： | 1 |
| 7 | Interaction of Ochratoxin A with Human Serum Albumin Preferential Binding of the Dianion and pH Effects显示文摘 | Ilichev Y V Perry J L Simon J D | 2002 | J Phys Chem B2002，106，3： | 1 |
| 8 | Synthesis of mechanical driver and power generation configurations(Ⅰ):Optimization framework 显示文摘 | Frank L Del Nogal Jin-Kuk Kim Simon Perry Robin Smith | 2010 | AIChE Journal2010，56，9： | 1 |
| 9 | Pediatric peritonsillar abscess:Quinsy ie versus interval tonsillectomy显示文摘 | SIMON L M MATIJASEC J W PERRY A P | 2013 | Int J Pediatr Otorhinolaryngol2013，77，： | 1 |
| 10 | Modulation of the Vitamin D3 Response by Cancer-Associated Mutant p53显示文摘 | Perry Stambolsky Yuval Tabach Giulia Fontemaggi Lilach Weisz Revital Maor-Aloni Zahava Sigfried Idit Shiff Ira Kogan Moshe Shay Eyal Kalo Giovanni Blandino Itamar Simon Moshe Oren Varda Rotter | 2010 | Cancer Cell2010，，3： | 1 |
| 11 | THE ROLE OF ROOT EXUDATES IN RHIZOSPHERE INTERACTIONS WITH PLANTS AND OTHER ORGANISMS显示文摘 | Harsh P. Bais Tiffany L. Weir Laura G. Perry Simon Gilroy Jorge M. Vivanco | 2006 | Annual Review of Plant Biology2006，，： | 1 |
| 12 | Prognostic factors and oncologic outcome in 146 patients with colorectal peritoneal carcinomatosis treated with cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy: Italian multicenter study S.I.T.I.L.O.显示文摘 | F. Cavaliere M. De Simone S. Virzì M. Deraco C.R. Rossi A. Garofalo F. Di Filippo D. Giannarelli M. Vaira M. Valle P. Pilati P. Perri M. La Pinta I. Monsellato F. Guadagni | 2010 | European Journal of Surgical Oncology2010，，2： | 1 |
| 13 | THE ROLE OF ROOT EXUDATES IN RHIZOSPHERE INTERACTIONS WITH PLANTS AND OTHER ORGANISMS显示文摘 | Harsh P. Bais Tiffany L. Weir Laura G. Perry Simon Gilroy Jorge M. Vivanco | 2006 | Annual Review of Plant Biology2006，，： | 1 |
| 14 | Matrix metalloproteinase levels are elevated in inflammatory bowel disease显示文摘 | Mark D. Baugh Michael J. Perry Anthony P. Hollander D.Rhodri Davies Simon S. Cross Alan J. Lobo Christopher J. Taylor Gareth S. Evans | 1999 | Gastroenterology1999，，4： | 1 |
| 15 | Effects of Pressure Overload on Extracellular Matrix Expression in the Heart of the Atrial Natriuretic Peptide–Null Mouse显示文摘 | Dajun Wang Suzanne Oparil Ji An Feng Peng Li Gilbert Perry Lan Bo Chen Meiru Dai Simon W.M. John Yiu-Fai Chen | 2003 | Hypertension: Journal of the American Heart Association2003，，1： | 1 |
| 16 | Impact behavior of plain concrete loading in uniaxial compression显示文摘 | Bischoff Peter H Perry Simon H | 1995 | Journal of Engineering Mechanics1995，121，6： | 1 |
| 17 | Impact behavior of plain concrete loaded in uniaxial compression 显示文摘 | Bischoff P Perry H Simon H | 1995 | Journal of Engineering Mechanics1995，121，： | 1 |
| 18 | Optimal Design of Mixed RofrigerantCyc]es 显示文摘 | Frank Del Nogal Jin Kuk IGm and Simon Perry | 2008 | Ind Eng Chem Res2008，47，22： | 1 |
| 19 | 心肌型脂肪酸结合蛋白是冠脉搭桥术后死亡和心室功能不全的独立预测因素显示文摘背景心肌型脂肪酸结合蛋白(heart-typefattyacidbindingprotein,hFABP)作为心肌脂肪酸的转运体,在心肌损害的早期即可释放入血。我们假设hFABP可用于早期预测冠脉搭桥术围术期心肌损害的发生,其敏感性更优于传统的心脏生物标志物。方法本研究为前瞻性队列研究,共纳入两家医疗机构体外循环下行冠脉搭桥术(coronaryarterybypassgraft,CABG)的患者1298例。在围术期的7个不同时点分别检测了血浆中的4种心肌损害标志物:hFABP、肌钙蛋白Ⅰ、心肌型肌酸激酶同工酶MB(creatingkinaseMB,CK-MB)以及肌红蛋白。采用Cox比例风险模型,评价围术期心肌标志物水平与心室功能不全、住院时间以及术后5年死亡率(时间中位数3.3年)的相关性。患者住院期间心室功能不全定义:需要新增加2种或以上的强心药物治疗、安置新的主动脉内球囊反搏、需要在术中停止体外循环时或者术后在监护室中使用心室辅助装置。结果hFABP对于心脏手术患者死亡率的阳性和阴性预测值分别为13%(95%可信区间,9%。19%)和95%(95%可信区间,94%-96%),高于肌钙蛋白Ⅰ和CK.MB。将其作为临床预测因素进行校正后,术后第1天hFABP水平及其峰值水平均是冠脉搭桥术后心室功能不全(P〈0.0001)、住院时间延长(P〈0.05)和5年死亡率增加(P〈0.0001)的独立预测因素。另外,术后第1天hFABP水平及其峰值水平在预测患者死亡率时显著优于研究纳入的其他生物标志物。在重复测量方差分析中,hFABP与其他拟合模型相比能更好的预测患者住院时间。术后第2天hFABP高于停止体外循环时水平的患者,其死亡率显著高于术后第2天hFABP低于停止体外循环时水平的患者(风险比,10.9;95%可信区间,5.0-23.7;P=7.2×10^-10)。出现延迟性hFABP峰值的120例患者(占患者总人数的10%)的死亡率为18.3%,未出现延迟性hFABP峰值患者的死亡率仅为4.7%。而是否出现肌钙蛋白Ⅰ和CK-MB的延迟峰值对患者死亡率无显著影响。结论与冠脉搭桥术后传统的心肌损伤标志物相比较,hFABP在CABG术后早期可达峰值,是一种更具优势的患者术后死亡和心室功能不全的独立预测因素。 | Jochen D. Muehlschlegel, MD Tjorvi E. Perry, MD Kuang-Yu Liu, PhD Amanda A. Fox, MD Charles D. Collard, MD Stanton K. Shernan, MD Simon C. Body, MD 刘媛媛(译) 彭丽桦(译) | 2012 | 麻醉与镇痛2012，8，1： | 0 |
| 20 | 英国女王的一天显示文摘伊丽莎白女王已经打破纪录,成为英国有史以来在位时间最长的君主,对她而言,最重要的就是始终如一。这位女性于1952年登基,当时25岁的她已经是两个孩子的妈妈。在担任君主的这65年的岁月中,她一直过着极其有规律的生活,这种生活规律一直保持不变,令人惊叹。 | Simon Perry 两袖清风 | 2017 | 新东方英语(中学版)2017，0，4： | 0 |
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