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| 1 | The role of oxidative stress in the toxicib induced by anlyloid β-peptide in Alzheimer's disease显示文摘 | Soledad M Carlos O Luis FL | 2000 | Progress in Neurobiology2000，62，： | 1 |
| 2 | Allopurinol and Progression of CKD and Cardiovascular Events: Long-term Follow-up of a Randomized Clinical Trial显示文摘 | Marian Goicoechea Soledad M. Garcia de Vinuesa Ursula Verdalles Eduardo Verde Nicolas Macias Alba Santos Ana Pérez de Jose Santiago Cede?o Tania Linares Jose Lu?o | 2014 | American Journal of Kidney Diseases2014，，： | 1 |
| 3 | Citrin deficiency, a perplexing global disorder显示文摘 | David Dimmock Bruno Maranda Carlo Dionisi-Vici Jing Wang Soledad Kleppe Giuseppe Fiermonte Renkui Bai Bryan Hainline Ada Hamosh William E. O’Brien Fernando Scaglia Lee-Jun Wong | 2008 | Molecular Genetics and Metabolism2008，，1： | 1 |
| 4 | Post-transcriptional regulation of seed dormancy and germination: Current understanding and future directions显示文摘Seed dormancy is a developmental checkpoint that prevents mature seeds from germinating under conditions that are otherwise favorable for germination.Temperature and light are themost relevant environmental factors that regulate seed dormancy and germination.These environmental cues can trigger molecular and physiological responses including hormone signaling,particularly that of abscisic acid and gibberellin.The balance between the content and sensitivity of these hormones is the key to the regulation of seed dormancy.Temperature and light tightly regulate the transcription of thousands of genes,as well as other aspects of gene expression such asmRNAsplicing,translation,and stability.Chromatin remodeling determines specific transcriptional outputs,and alternative splicing leads to different outcomes and produces transcripts that encode proteins with altered or lost functions.Proper regulation of chromatin remodeling and alternative splicing may be highly relevant to seed germination.Moreover,microRNAs are also critical for the control of gene expression in seeds.This review aims to discuss recent updates on post-transcriptional regulation during seed maturation,dormancy,germination,and post-germination events.We propose future prospects for understanding howdifferent post-transcriptional processes in crop seeds can contribute to the design of genotypes with better performance and higher productivity. | Rocío Soledad Tognacca Javier Francisco Botto | 2021 | Plant Communications2021，2，4： | 1 |
| 5 | Circulating levels and hepatic expression of molecular mediators of atherosclerosis in nonalcoholic fatty liver disease显示文摘 | Silvia Sookoian Gustavo O. Casta?o Adriana L. Burgue?o María Soledad Rosselli Tomas Fernández Gianotti Pablo Mallardi Julio San Martino Carlos Jose Pirola | 2009 | Atherosclerosis2009，，2： | 1 |
| 6 | Do MSIL sporadic colorectal tumors develop through “mild mutator pathway”显示文摘 | Soledad O Cristina M S Mariano M A | 2006 | Clin Oncol2006，29，4： | 1 |
| 7 | The role of oxidative stress in the toxicity induced by amyloid β-peptide in Alzheimers disease显示文摘 | Soledad M Carlos O Luis FL | 2000 | Progress in Neurobiology2000，62，6： | 1 |
| 8 | Palynology of the To areian-Aalenian global boundary stratotype section and point (GSSP) at Fuentelsaz (Lower Middle Jurassic, Iberian Range, Spain)显示文摘 | Eduardo B Soledad U Antonio O | 2010 | Review of Palaeobotany and Palynology2010，162，1： | 1 |
| 9 | Application of fast ultrasound water-bath assisted enzymatic hydrolysis – High performance liquid chromatography–inductively coupled plasma-mass spectrometry procedures for arsenic speciation in seafood materials显示文摘 | Antonio Moreda-Pi?eiro Jorge Moreda-Pi?eiro Paloma Herbello-Hermelo Pilar Bermejo-Barrera Soledad Muniategui-Lorenzo Purificación López-Mahía Darío Prada-Rodríguez | 2011 | Journal of Chromatography A2011，，39： | 1 |
| 10 | Nat Genet:科学家设计新方法找到抑制癌症发育的新基因显示文摘英国桑格研究院的研究人员和他们的合作者们最近发现了帮助阻止前列腺癌、皮肤癌和乳腺癌发育的新基因。这些基因能够与众所周知的肿瘤抑制基因PTEN配合发挥作用,该研究还发现这些基因与人类前列腺肿瘤存在相关性。相关研究结果发表在国际学术期刊Nature Genetics上。该研究揭示了一些参与癌症发育的新途径,这些基因有望成为治疗PTEN突变癌症的新药物靶点。这项研究开发的一些方法也可以用于发现其他协同抑制癌症生长的基因。 | Jorge de la Rosa, Mathias Josef Friedrich, Yilong Li, Lena Rad, Hannes Ponstingl, Qi Liang, Sandra Bernaldo de Quirós, Imran Noorani, Emmanouil Metzakopian, Alexander Strong, Meng Amy Li, Gary J Hoffman, Rocío Fuente, George S Vassiliou, Roland Rad, Allan Bradley Juan Cadiñanos Jorge de la Rosa Juan Cadiñanos Jorge de la Rosa Carlos López-Otín Julia Weber Roland Rad Julia Weber Roland Rad Aurora Astudillo María Teresa Fernández-García María Soledad Fernández-García Gary J Hoffman Carlos López-Otín | 2017 | 现代生物医学进展2017，17，15： | 0 |
| 11 | Enhanced depth OCT imaging of the lamina cribrosa for 24 hours显示文摘The lamina cribrosa thickness(LCT) could be affected by dynamic changes in its structure.Using spectral-domainoptical coherence tomography(SD-OCT),we have studied the behaviour of the laminar region in 14 young subjects over 24 h.Significant changes in LCT were observed,depending on the time at which the measurement was taken,with the maximum thickness being observed at 7.30 p.m.,and the minimum at 7.30 a.m.This finding could suggests a circadian pattern in the LCT thickness in healthy subjects,which could have implications for the classification,diagnosis and prognosis of both normal and glaucomatous subjects. | Pedro Naranjo Bonilla Rafael Giménez Gómez David Ríos Jiménez María Luísa Varas Fabra María del Carmen Munoz Villanueva Rocío García Catalán Pilar Font Ugalde María Soledad Poblador Fernández JoséLuís Lancho Alonso JoséMaría Gallardo Galera | 2017 | International Journal of Ophthalmology(English edition)2017，10，2： | 0 |
| 12 | Implementation of a virtual multicenter gastrointestinal tumor board to reduce cancer disparities in Argentina显示文摘Given the increasing complexity of cancer care,multidisciplinary tumor boards have become essential in daily clinical oncology practice.The Project Extension for Community Healthcare Outcomes(ECHO)initiative developed an innovative telementoring model using a'hub and spoke'design consisting of a team of experts(hub)that offers a full service to multiple participants(the spokes)during regularly scheduled sessions discussing patients'clinical cases.The Alexander Fleming Cancer Institute in Buenos Aires was the first hub in Latin America to implement Project ECHO for gastrointestinal tumors.In our 3-year experience,80 patients from 37 centers were evaluated within Project ECHO and a range of three to five cases were discussed in each meeting.From our perspective,the impact of this novel approach was a remarkable strategy to reduce care disparities by equalizing access to high-quality medical knowledge in a multidisciplinary environment for medical discussions.Additionally,it was shown to have a cost-effective impact directly on the patients and the local health system,since relevant costs were saved after unnecessary treatments,studies and travel expenses were avoided. | Federico Esteso Natalia Soledad Tissera Juan Manuel O'Connor Romina Luca Eduardo Huertas Fernando Sánchez Loria Ivana Pedraza Alejandro Pairola Fernando Brancato Lisandro Paganini Mariana Kucharczyk Mora Amat Maria Teresa Pombo Mariana Galli Luisina Bruno Luis Caro Andrés Rodriguez Diego Enrico Federico Waisberg Matías Chacón | 2022 | World Journal of Clinical Oncology2022，13，6： | 0 |
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