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| 1 | First-line single-agent cetuximab in elderly patients with metastatic colorectal cancer. A phase II clinical and molecular study of the Spanish group for digestive tumor therapy (TTD)显示文摘 | J. Sastre E. Aranda C. Grávalos B. Massutí M. Varella-Garcia F. Rivera G. Soler A. Carrato J.L. Manzano E. Díaz-Rubio M. Hidalgo | 2009 | Critical Reviews in Oncology and Hematology2009，，1： | 2 |
| 2 | ddRAD sequencing-based genotyping for population structure analysis in cultivated tomato provides new insights into the genomic diversity of Mediterranean‘da serbo’type long shelf-life germplasm显示文摘Double digest restriction-site associated sequencing(ddRAD-seq)is a flexible and cost-effective strategy for providing in-depth insights into the genetic architecture of germplasm collections.Using this methodology,we investigated the genomic diversity of a panel of 288 diverse tomato(Solanum lycopersicum L.)accessions enriched in‘da serbo’(called‘de penjar’in Spain)long shelf life(LSL)materials(152 accessions)mostly originating from Italy and Spain.The rest of the materials originate from different countries and include landraces for fresh consumption,elite cultivars,heirlooms,and breeding lines.Apart from their LSL trait,‘da serbo’landraces are of remarkable interest for their resilience.We identified 32,799 high-quality SNPs,which were used for model ancestry population structure and non-parametric hierarchical clustering.Six genetic subgroups were revealed,clearly separating most‘da serbo’landraces,but also the Spanish germplasm,suggesting a subdivision of the population based on type and geographical provenance.Linkage disequilibrium(LD)in the collection decayed very rapidly within<5 kb.We then investigated SNPs showing contrasted minor frequency allele(MAF)in‘da serbo’materials,resulting in the identification of high frequencies in this germplasm of several mutations in genes related to stress tolerance and fruit maturation such as CTR1 and JAR1.Finally,a mini-core collection of 58 accessions encompassing most of the diversity was selected for further exploitation of key traits.Our findings suggest the presence of a genetic footprint of the‘da serbo’germplasm selected in the Mediterranean basin.Moreover,we provide novel insights on LSL‘da serbo’germplasm as a promising source of alleles for tolerance to stresses. | Salvatore Esposito Teodoro Cardi Gabriele Campanelli Sara Sestili María JoséDíez Salvador Soler Jaime Prohens Pasquale Tripodi | 2020 | Horticulture Research2020，7，1： | 2 |
| 3 | Developmental switches in chemokine response profiles during B cell differentiation and maturation显示文摘 | Campbell JJ Soler D | 2000 | J Exp Med2000，191，8： | 1 |
| 4 | Analysis of B and T cell clonality and HLA class Ⅱ alleles in patients with idio- pathic thrombocytopenic purpura: correlation with Helico- bacter pylori infection and response to eradication treatment 显示文摘 | Veneri D De Matteis G Soler P | 2005 | Platelats2005，16，5： | 1 |
| 5 | Angiotensin-converting enzyme 2: enhancing the degradation ofangiotemin ]I as a potential therapy for diabetic nephropathy显示文摘 | Batlle D Wysocki J Soler M J | 2012 | Kidney Int2012，81，6： | 1 |
| 6 | Nanocrystalline transition-metal oxide spheres with controlled multi-scale porosity 显示文摘 | Grosso D Soler Illia G J de A A Crepaldi E L | 2003 | Adv Funct Mater2003，13，1： | 1 |
| 7 | Developmental switches in chemokine response profiles during B cell diffe-rentiation and maturation显示文摘 | Campbell JJ Soler D | 2000 | J Exp Med2000，191，8： | 1 |
| 8 | Differential chemokine responses and homing patterns of murine TCR alpha beta NKT cell subsets显示文摘 | Kim CH Soler D | 2003 | J Immunol2003，171，： | 1 |
| 9 | Recent advances in liver imaging 显示文摘 | Mutter D Soler L Marescaux J | 2010 | Expert Rev Gastroenterol Hepatol2010，4，5： | 1 |
| 10 | Sarcoidosis显示文摘 | Nunes H Bouvry D Soler P | 2007 | Orphanet J of Rare Dis- eases2007，2，： | 1 |
| 11 | Density-func- tional method for very large systems with LCAO basis sets 显示文摘 | Sanchez-Portal D Ordejon P Soler J M | 1997 | Int J Quantum Chem1997，65，： | 1 |
| 12 | Analysis of 13000 unique citrus clusters associated with fruit quality ,production and salinity tolerance显示文摘 | TEROL J CONESA A COLMENERO J CERCOS M TADEO F AGUSTI J ALOS E ANDRES F SOLER G BRUMOS J IGLESIAS D GOTZ S LEGAZ F ARGOIUT X COURTOIS B OLLITRAULT P DOSSART C WINCKER P MORILLON R TALON M | 2007 | BMC Genomics2007，8，： | 1 |
| 13 | Differential chemokine responses and homing patterns of murine TCR alphabeta NKT cell subsets显示文摘 | Johnston B Kim CH Soler D | 2003 | J lmmunol2003，171，6： | 1 |
| 14 | Calculation of the elastic demand curve for a day-ahead secondary reserve market显示文摘 | SOLER D FRJAS P GOMEZ T | 2010 | IEEE Trans on Power Systems2010，25，2： | 1 |
| 15 | Evolution of tolerance by magpies to brood parasitism by great spotted cuckoos显示文摘 | Soler JJ Martín-Gálvez D Martínez JG Soler M Canestrari D Abad-Gomez JM M(o)ller AP | | 0，，： | 1 |
| 16 | Angiotensin-conver- ring enzyme 2 : enhancing the degradation of angiotensin Ill as a potential therapy for diabetic nephropathy显示文摘 | Batlle D Wysocki J Soler MJ | 2012 | Kidney Int2012，81，： | 1 |
| 17 | ACE2 and diabetes: ACE of ACEs? 显示文摘 | Batlle D Jose Soler M Ye M | 2010 | Diabetes2010，59，12： | 1 |
| 18 | Recent advances in liver imaging 显示文摘 | Mutter D Soler L Marescaux J | 2010 | Expert Rev Gastroenterol Hepatol2010，4，5： | 1 |
| 19 | Recent advances in liver imaging显示文摘 | Mutter D Soler L Marescaux J | 2010 | Hepatol2010，4，5： | 1 |
| 20 | CCR8 expression identi fies CD4 memory T cells entriched for FOXP^3+ regulatory and Th2 effector lymphocytes 显示文摘 | Soler D Chapman TR Poisson LR | 2006 | J Immunol2006，177，10： | 1 |
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