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您的检索式：作者名="Stallhofer"
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| 1 | Lipocalin-2 Is a Disease Activity Marker in Inflammatory Bowel Disease Regulated by IL-17A, IL-22, and TNF-α and Modulated by IL23R Genotype Status显示文摘 | Johannes Stallhofer Matthias Friedrich Astrid Konrad-Zerna Martin Wetzke Peter Lohse Jürgen Glas Cornelia Tillack-Schreiber Fabian Schnitzler Florian Beigel Stephan Brand | 2015 | Inflammatory Bowel Diseases2015，，10： | 2 |
| 2 | Analysis of IL2/IL21 gene variants in cholestatic liver diseases revealsan association with primary sclerosing cholangitis显示文摘 | Stallhofer J Denk GU Glas J ? | 2011 | Digestion2011，84，1： | 1 |
| 3 | Intestinal Wnt in the transition from physiology to oncology显示文摘Adult stem cells are necessary for self-renewal tissues and regeneration after damage.Especially in the intestine,which self-renews every few days,they play a key role in tissue homeostasis.Therefore,complex regulatory mechanisms are needed to prevent hyperproliferation,which can lead in the worst case to carcinogenesis or under-activation of stem cells,which can result in dysfunctional epithelial.One main regulatory signaling pathway is the Wnt/β-catenin signaling pathway.It is a highly conserved pathway,withβ-catenin,a transcription factor,as target protein.Translocation ofβ-catenin from cytoplasm to nucleus activates the transcription of numerous genes involved in regulating stem cell pluripotency,proliferation,cell differentiation and regulation of cell death.This review presents a brief overview of the Wnt/β-catenin signaling pathway,the regulatory mechanism of this pathway and its role in intestinal homeostasis.Additionally,this review highlights the molecular mechanisms and the histomorphological features of Wnt hyperactivation.Furthermore,the central role of the Wnt signaling pathway in intestinal carcinogenesis as well as its clinical relevance in colorectal carcinoma are discussed. | Julia Swoboda Patrick Mittelsdorf Yuan Chen Ralf Weiskirchen Johannes Stallhofer Silke Schüle Nikolaus Gassler | 2022 | World Journal of Clinical Oncology2022，13，3： | 1 |
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