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| 1 | Relationship between the exocrine and endocrine pancreas after acute pancreatitis显示文摘AIM:To determine the prevalence and time course of pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.METHODS:Relevant literature cited in three major biomedical journal databases(EMBASE,MEDLINE,and Scopus)was reviewed independently by two authors.There were no language constraints but the search was limited to human studies.Studies included were cohort studies of adult patients who were discharged after an attack of acute pancreatitis.Patients were excluded if they were under 18 years of age or had a previous diagnosis of prediabetes or diabetes mellitus,pancreatic exocrine insufficiency,or chronic pancreatitis.The main outcome measure was the prevalence of concomitant pancreatic exocrine insufficiency in patients who were diagnosed with prediabetes and diabetes mellitus after an attack of acute pancreatitis.Subgroup analysis was conducted for patients who were diagnosed with prediabetes only and those who were diagnosed withdiabetes mellitus only.Subgroup analysis looking at the time course of concomitant pancreatic exocrine and endocrine insufficiency was also conducted.Pooled prevalence and corresponding 95%confidence intervals were calculated for all outcome measures and P-values<0.05 were deemed statistically significant.RESULTS:Eight clinical studies comprising of 234patients met all eligibility criteria.The pooled prevalence of newly diagnosed prediabetes or diabetes in individuals after acute pancreatitis was 43%(95%CI:30%-56%).The pooled prevalence of pancreatic exocrine insufficiency in individuals after acute pancreatitis was 29%(95%CI:19%-39%).The prevalence of concomitant pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes was 40%(95%CI:25%-55%).The prevalence of concomitant pancreatic exocrine insufficiency among individuals with prediabetes alone and diabetes mellitus alone was 41%(95%CI:12%-75%)and 39%(95%CI:28%-51%),respectively.Further analysis showed that the prevalence of concomitant pancreatic exocrine insufficiency in individuals with prediabetes or diabetes decreases over time after an attack of acute pancreatitis.CONCLUSION:Pancreatic exocrine insufficiency occurs in 40%of individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.Further studies are needed to investigate the pathogenesis of diabetes in this setting. | Stephanie L M Das James I C Kennedy Rinki Murphy Anthony R J Phillips John A Windsor Maxim S Petrov | 2014 | World Journal of Gastroenterology2014，20，45： | 9 |
| 2 | Predictors of suboptimal bowel preparation in asymptomatic patients undergoing average-risk screening colonoscopy显示文摘AIM To identify risk factors for a suboptimal preparation among a population undergoing screening or surveillance colonoscopy.METHODS Retrospective review of the University of Michigan and Veteran's Administration(VA) Hospital records from 2009 to identify patients age 50 and older who underwent screening or surveillance procedure and had resection of polyps less than 1 cm in size and no more than 2 polyps. Patients with inflammatory bowel disease or a family history of colorectal cancer were excluded. Suboptimal procedures were defined as procedure preparations categorized as fair, poor or inadequate by the endoscopist. Multivariable logistic regression was used to identify predictors of suboptimal preparation.RESULTS Of 4427 colonoscopies reviewed, 2401 met our inclusion criteria and were analyzed. Of our population, 16% had a suboptimal preparation. African Americans were 70% more likely to have a suboptimal preparation(95%CI: 1.2-2.4). Univariable analysis revealed that narcotic and tricyclic antidepressants(TCA) use, diabetes, prep type, site(VA vs non-VA), and presence of a gastroenterology(GI) fellow were associated with suboptimal prep quality. In a multivariable model controlling for gender, age, ethnicity, procedure site and presence of a GI fellow, diabetes [odds ratio(OR) = 2.3; 95%CI: 1.6-3.2], TCA use(OR = 2.5; 95%CI: 1.3-4.9), narcotic use(OR = 1.7; 95%CI: 1.2-2.5) and Miralax-Gatorade prep vs 4L polyethylene glycol 3350(OR = 0.6; 95%CI: 0.4-0.9) were associated with a suboptimal prep quality. CONCLUSION Diabetes, narcotics use and TCA use were identified as predictors of poor preparation in screening colonoscopies while Miralax-Gatorade preps were associated with better bowel preparation. | Shail M Govani Eric E Elliott Stacy B Menees Stephanie L Judd Sameer D Saini Constantinos P Anastassiades Annette L Urganus Suzanna J Boyce Philip S Schoenfeld | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，17： | 7 |
| 3 | Unique case of presumed lisinopril-induced hepatotoxicity显示文摘 | Sandip KZ Saurabh S Stephanie L | 2010 | Am J Health- Syst Pharm2010，67，16： | 1 |
| 4 | Bacterial RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited condition 显示文摘 | Paolo C Dave W Robert J B Don C A Jay H Martin S Mark A Ganesh K Sara S Robert D Santiago N Stephanie B Mary F Jayaprakash T Santanu D Christopher B Michael H L Jacqueline E H | 2008 | Plant Physiology2008，147，2： | 1 |
| 5 | Providing social support may be more beneficial than receiving it: Results from a prospective study of mortality显示文摘 | Stephanie L B Randolph M N Amiram D V Dylan M S | 2003 | Psychology Science2003，，4： | 1 |
| 6 | Carvedilol therapy in pediatric patients with congestive heart failure: a study in- vestigating clinical and pharmacokinetic parameters 显示文摘 | Stephanie L Thomas S Frederike B | 2002 | Am Heart J2002，143，： | 1 |
| 7 | Carvedilol therapy in pediatric patients with congestive heart failure: a study investi- gating clinical and pharmacokinetic parameters 显示文摘 | Stephanie L Thorns S Frederike B | 2002 | Am Heart J2002，143，： | 1 |
| 8 | Calcium addition at the hubbard brook experimental forest increases the capacity forstress tolerance and carbon capture in red spruce trees during the cold season显示文摘 | PAUL G S RAKESH M STEPHANIE L | 2011 | Trees2011，25，6： | 1 |
| 9 | Turf grass establishment on various root zones显示文摘 | James A M H iranthi S Josh A H Lawson T J Stephanie L M | 2004 | USGA Green Section Record2004，42，4： | 1 |
| 10 | Data gathering algorithms in sensor networks using energy metrics显示文摘 | STEPHANIE L CAULIGI R KRISHNA M S | 2002 | IEEE Transactions on Parallel and Distributed Systems2002，13，9： | 1 |
| 11 | Processing, mosaicking and management of the Monterey Bay digital sidescan-sonar images显示文摘 | Pat S Chavez JoAnn Isbrecht Peter Galanis Gregory L Gabel Stuart C Sides Deborah L Soltesz Stephanie L Ross Miguel G Velasco | 2002 | Marine Geology2002，，1： | 1 |
| 12 | Isotopes of volatile organic compounds: an emerging approach for studying atmospheric budgets and chemistry显示文摘 | ALLEN H G STEPHANIE L S | 2003 | Chem Rev2003，103，： | 1 |
| 13 | Prevalence, course,and risk factors for antenatal anxiety and depression 显示文摘 | Antoinetle M L Siu K L Stephanie M S | 2007 | Obstetricis Gynecol2007，110，5： | 1 |
| 14 | Calcium Plus Vitamin D Supplementation and the Risk of Incident Diabetes in the Women’s Health Initiative显示文摘 | Connelly Stephanie Curb J David Howard Barbara V Kestenbaum Bryan Larson Joseph C Manson JoAnn E Margolis Karen L Siscovick David S Weiss Noel S | 2008 | Diabetes Care2008，，4： | 1 |
| 15 | Antioxidant defensesystem is altered by dietary oxidized lipid in first -feedingrainbow trout (Oncorhynchus mykiss) 显示文摘 | Stephanie F Emilie L Anne S | 2014 | Aquaculture2014，，： | 1 |
| 16 | Prenatal Phthalate Exposure Is Associated with Childhood Behavior and Executive Functioning显示文摘 | Engel Stephanie M Miodovnik Amir Canfield Richard L Zhu Chenbo Silva Manori J Calafat Antonia M Wolff Mary S | 2010 | Environmental Health Perspectives2010，，4： | 1 |
| 17 | Chemicals Present in Automobile Traffie Tunnels and the Possible Community Health Hazards:A Review of the Literature显示文摘 | Jim R K Stephanie L S Dennis P | | 0，，09： | 1 |
| 18 | The children's sleep habits questionnaire in toddlers and preschool children显示文摘 | Beth L G Stephanie L S Karen T | 2008 | J Dev Behav Pediatr2008，29，2： | 1 |
| 19 | Postopera- tive radiotherapy for advanced medullary thyroid cancer- local disease control in the modern era显示文摘 | Schwartz D L Vishal R Stephanie S | 2008 | Head & Neck2008，30，7： | 1 |
| 20 | When Should Endometrial Polyps Be Treated显示文摘 | Stephanie Cruz L Brent S Andrew M | 2012 | Curr Obstet Gynecol Rep2012，，1： | 1 |
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