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| 1 | Pregnancy and inflammatory bowel diseases: Current perspectives, risks and patient management显示文摘Inflammatory bowel diseases(IBD) are chronic idiopathic inflammatory conditions characterized by relapsing and remitting episodes of inflammation which can affect several different regions of the gastrointestinal tract, but also shows extra-intestinal manifestations. IBD is most frequently diagnosed during peak female reproductive years, with 25% of women with IBD conceiving after their diagnosis. While IBD therapy has improved dramatically with enhanced surveillance and more abundant and powerful treatment options, IBD disease can have important effects on pregnancy and presents several challenges for maintaining optimal outcomes for mothers with IBD and the developing fetus/neonate. Women with IBD, the medical team treating them(both gastroenterologists and obstetricians/gynecologists) must often make highly complicated choices regarding conception, pregnancy, and post-natal care(particularly breastfeeding) related to their choice of treatment options at different phases of pregnancy as well as post-partum. This current review discusses current concerns and recommendations for pregnancy duringIBD and is intended for gastroenterologists, general practitioners and IBD patients intending to become,(or already) pregnant, and their families. We have addressed patterns of IBD inheritance, effects of IBD on fertility and conception(in both men and women), the effects of IBD disease activity on maintenance of pregnancy and outcomes, risks of diagnostic procedures during pregnancy and potential risks and complications associated with different classes of IBD therapeutics. We also have evaluated the clinical experience using 'top-down' care with biologics, which is currently the standard care at our institution. Post-partum care and breastfeeding recommendations are also addressed. | Pegah Hosseini-Carroll Monica Mutyala Abhishek Seth Shaheen Nageeb Demiana Soliman Moheb Boktor Ankur Sheth Jonathon Chapman James Morris Paul Jordan Kenneth Manas Felix Becker Jonathan Steven Alexander | 2015 | World Journal of Gastrointestinal Pharmacology and Therapeutics2015，6，4： | 4 |
| 2 | Endogenous Glucagon-Like Peptide-1 Slows Gastric Emptying in Healthy Subjects, Attenuating Postprandial Glycemia显示文摘 | Adam M. Deane Nam Q. Nguyen Julie E. Stevens Robert J. L. Fraser Richard H. Holloway Laura K. Besanko Carly Burgstad Karen L. Jones Marianne J. Chapman Chris K. Rayner Michael Horowitz | 2010 | The Journal of Clinical Endocrinology & Metabolism2010，，1： | 1 |
| 3 | 18Fluorodeoxyglucose-Positron Emission Tomography in the Management of Patients With Suspected Pancreatic Cancer显示文摘 | D. Michael Rose Dominique Delbeke R. Daniel Beauchamp William C. Chapman Martin P. Sandler Kenneth W. Sharp William O. Richards J. Kelly Wright Maria E. Frexes C. Wright Pinson Steven D. Leach | 1999 | Annals of Surgery1999，，5： | 1 |
| 4 | Bile duct injuries 12 years after the introduction of laparoscopic cholecystectomy显示文摘 | William C. Chapman M.D Michael Abecassis M.D. William Jarnagin M.D. Sean Mulvihill M.D. Steven M. Strasberg M.D | 2003 | Journal of Gastrointestinal Surgery2003，，3： | 1 |
| 5 | Detec- tion of the virulent form of AVR3a from Phytophthora infestans following artificial evolution of potato resis- tance gene R3a 显示文摘 | Chapman S Stevens L J Boevink P C | 2014 | PLoS ONE2014，9，11： | 1 |
| 6 | Long-term effects of maximally intensive statin therapy on changes in coronary atheroma composition: insights from SATURN显示文摘 | Rishi Puri Peter Libby Steven E. Nissen Kathy Wolski Christie M. Ballantyne Phillip J. Barter M. John Chapman Raimund Erbel Joel S. Raichlen Kiyoko Uno Yu Kataoka E. Murat Tuzcu Stephen J. Nicholls | 2014 | European Heart Journal – Cardiovascular Imaging2014，，： | 1 |
| 7 | Myocarditis and Heart Failure Associated With Hepatitis C Virus Infection显示文摘 | Akira Matsumori Toshio Shimada Nora M. Chapman Steven M. Tracy Jay W. Mason | 2006 | Journal of Cardiac Failure2006，，4： | 1 |
| 8 | Coronary atheroma volume and cardiovascular events during maximally intensive statin therapy显示文摘 | Rishi Puri Steven E. Nissen Mingyuan Shao Christie M. Ballantyne Phillip J. Barter M. John Chapman Raimund Erbel Peter Libby Joel S. Raichlen Kiyoko Uno Yu Kataoka Stephen J. Nicholls | 2013 | European Heart Journal2013，，41： | 1 |
| 9 | Characteristic brain magnetic resonance imaging pattern in patients with macrocephaly and PTEN mutations显示文摘 | Adeline Vanderver Davide Tonduti Ilana Kahn Johanna Schmidt Livija Medne Jodie Vento Kimberly A. Chapman Brendan Lanpher Phillip Pearl Andrea Gropman Charles Lourenco John‐Steven Bamforth Cynthia Sharpe Mercédes Pineda Jens Schallner Olaf Bodamer Simona O | 2014 | Genet2014，，3： | 1 |
| 10 | Gastric Emptying, Incretin Hormone Secretion, and Postprandial Glycemia in Cystic Fibrosis—Effects of Pancreatic Enzyme Supplementation显示文摘 | Paul Kuo Julie E. Stevens Antonietta Russo Anne Maddox Judith M. Wishart Karen L. Jones Hugh Greville David Hetzel Ian Chapman Michael Horowitz Christopher K. Rayner | 2011 | The Journal of Clinical Endocrinology & Metabolism2011，，5： | 1 |
| 11 | Impact of statins on progression of atherosclerosis: rationale and design of SATURN (Study of Coronary Atheroma by InTravascular Ultrasound: Effect of Rosuvastatin versus AtorvastatiN)显示文摘 | Stephen J. Nicholls Marilyn Borgman Steven E. Nissen Joel S. Raichlen Christie Ballantyne Philip Barter M. John Chapman Raimund Erbel Peter Libby | 2011 | Current Medical Research & Opinion2011，，6： | 1 |
| 12 | Genomic determinants of cardiovirulence in coxsackievirus B3 clinical Isolates: localization to the 5' nontranslated region显示文摘 | James J Dunn Nora M Chapman Steven Tracy | 2000 | J Virol2000，74，10： | 1 |
| 13 | 氢氯噻嗪和阿替洛尔的降压作用及对代谢的影响显示文摘除影响血压水平外,噻嗪类利尿剂和β受体阻滞剂还会造成不良的代谢作用(adversemetaboliceffects,AME),这两种影响是否由相同的机制造成还不明确。 | Steven M. Smith Yan Gong Stephen T. Turner Rhonda M. Cooper-DeHoff Amber L. Beitelshees Arlene B. Chapman Eric Boerwinkle Kent Bailey Julie A. Johnson John G. Gums 罗冬梅 叶鹏 | 2012 | 中华高血压杂志2012，20，6： | 1 |
| 14 | Convenient and inexpensive procedure for oxidation of secondary alcohols to ketones 显示文摘 | Stevens R V Chapman K T Weller H N | 1980 | J Org Chem1980，45，10： | 1 |
| 15 | Bile duct injuries 12 years after the introduction of laparoscopic cholecystectomy显示文摘 | William C. Chapman Michael Abecassis William Jarnagin Sean Mulvihill Steven M. Strasberg | 2003 | Journal of Gastrointestinal Surgery2003，，3： | 1 |
| 16 | C-Reactive Protein, but not Low-Density Lipoprotein Cholesterol Levels, Associate With Coronary Atheroma Regression and Cardiovascular Events After Maximally Intensive Statin Therapy显示文摘 | Rishi Puri Steven E. Nissen Peter Libby Mingyuan Shao Christie M. Ballantyne Phillip J. Barter M. John Chapman Raimund Erbel Joel S. Raichlen Kiyoko Uno Yu Kataoka Stephen J. Nicholls | 2013 | Circulation2013，，22： | 1 |
| 17 | 盛夏,携一缕清凉入心显示文摘Salad Servers由实心山毛榉木制成的沙拉搅拌勺,外形看上去就像是一对网球拍,兼具实用性与美观性,当作礼物送给素食主义者、网球爱好者或喜欢趣味设计的朋友是不是再好不过呢?(设计:Matt Chapman)盛夏,气温节节攀升,高温预警似乎每天都在发着警告,柔风夹裹热浪扑面而来,带来闷热的窒息感,人们想尽办法地消暑解热,假日的海边总是挤满了人潮,卖冷饮的店家更是座无虚席。到了夜晚,穿一双简单的人字拖鞋,配上拉风的短裤,即使是转钟过后的凌晨时分,街道两旁的烧烤摊依旧生意兴隆,要上一打生蚝,一盘扇贝再配上几瓶冰啤酒下肚,清凉从从唇间直透心间,销魂得觉得幸福不过如此。 | AANDERSSON Benjamin Hubert Matt Chapman Muubs Malene Lütken Norm Architects Pablo Figuera & álvaro Goula Preutz & Wihlborg & Braasch & Karlsson SUCKUK Spark & Rocket Simon Stevens Torben J?rgensen wmf 伏平 范嘉苑 | 2016 | 现代装饰(家居)2016，，8： | 0 |
| 18 | X-ray focusing with efficient high-NA multilayer Laue lenses显示文摘Multilayer Laue lenses are volume diffraction elements for the efficient focusing of X-rays.With a new manufacturing technique that we introduced,it is possible to fabricate lenses of sufficiently high numerical aperture(NA)to achieve focal spot sizes below 10 nm.The alternating layers of the materials that form the lens must span a broad range of thicknesses on the nanometer scale to achieve the necessary range of X-ray deflection angles required to achieve a high NA.This poses a challenge to both the accuracy of the deposition process and the control of the materials properties,which often vary with layer thickness.We introduced a new pair of materials—tungsten carbide and silicon carbide—to prepare layered structures with smooth and sharp interfaces and with no material phase transitions that hampered the manufacture of previous lenses.Using a pair of multilayer Laue lenses(MLLs)fabricated from this system,we achieved a two-dimensional focus of 8.4×6.8 nm2 at a photon energy of 16.3 keV with high diffraction efficiency and demonstrated scanning-based imaging of samples with a resolution well below 10 nm.The high NA also allowed projection holographic imaging with strong phase contrast over a large range of magnifications.An error analysis indicates the possibility of achieving 1 nm focusing. | Saša Bajt Mauro Prasciolu Holger Fleckenstein Martin Domaracký Henry N Chapman Andrew J Morgan Oleksandr Yefanov Marc Messerschmidt Yang Du Kevin T Murray Valerio Mariani Manuela Kuhn Steven Aplin Kanupriya Pande Pablo Villanueva-Perez Karolina Stachnik Joe PJ Chen Andrzej Andrejczuk Alke Meents Anja Burkhardt David Pennicard Xiaojing Huang Hanfei Yan Evgeny Nazaretski Yong S Chu Christian E Hamm | 2017 | Light(Science & Applications)2017，6，1： | 0 |
| 19 | Deriving the coronal hole electron temperature: electron density dependent ionization / recombination considerations显示文摘Comparison of appropriate theoretically derived line ratios with observational data can yield estimates of a plasma’s physical parameters,such as electron density or temperature.The usual practice in the calculation of the line ratio is the assumption of excitation by electrons/protons followed by radiative decay.Furthermore,it is normal to use the so-called coronal approximation,i.e.one only considers ionization and recombination to and from the ground-state.A more accurate treatment is to include ionization/recombination to and from metastable levels.Here,we apply this to two lines from adjacent ionization stages,Mg IX 368 and Mg X 625 ,which has been shown to be a very useful temperature diagnostic.At densities typical of coronal hole conditions,the difference between the electron temperature derived assuming the zero density limit compared with the electron density dependent ionization/recombination is small.This,however,is not the case for flares where the electron density is orders of magnitude larger.The derived temperature for the coronal hole at solar maximum is around 1.04MK compared to just below 0.82MK at solar minimum. | John Gerard Doyle Steven Chapman Paul Bryans David Pérez-Suárez Avninda Singh Hugh Summers Daniel Wolf Savin | 2010 | Research in Astronomy and Astrophysics2010，10，1： | 0 |
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