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| 1 | Fat cell-secreted adiponectin mediates physical exercise-induced hippocampal neurogenesis: an alternative anti-depressive treatment?显示文摘Psychological depression is drawing accumulating attention nowadays, due to the skyrocketing incidence worldwide and the enormous burdens it incurs. Physical exercise has been long recognized for its therapeutic effects on depressive disorders, although knowledge of the underlying mechanisms remains limited. Suppressed hippocampal neurogenesis in adult brains has been regarded, at least partly, contributive to depression, whereas physical exercise that restores neurogenesis accordingly exerts the anti-depressive action. Several recent publications have suggested the potential role of adiponectin, a protein hormone secreted by peripheral mature adipocytes, in mediating physical exercise-triggered enhancement of hippocampal neurogenesis and alleviation of depression. Here, we briefly review these novel findings and discuss the possibility of counteracting depression by modulating adiponectin signaling in the hippocampus with interventions including physical exercise and administration of pharmacological agents. | Suk Yu Yau Ang Li Aimin Xu Kwok-fai So | 2015 | Neural Regeneration Research2015，10，1： | 7 |
| 2 | Differential diagnosis of left-sided abdominal pain:Primary epiploic appendagitis vs colonic diverticulitis显示文摘AIM:To investigate the clinical characteristics of left primary epiploic appendagitis and to compare them with those of left colonic diverticulitis.METHODS:We retrospectively reviewed the clinical records and radiologic images of the patients who presented with left-sided acute abdominal pain and had computer tomography(CT) performed at the time of presentation showing radiological signs of left primary epiploic appendagitis(PEA) or left acute colonic diverticulitis(ACD) between January 2001 and December 2011. A total of 53 consecutive patients were enrolled and evaluated. We also compared the clinical characteristics,laboratory findings,treatments,and clinical results of left PEA with those of left ACD.RESULTS:Twenty-eight patients and twenty-five patients were diagnosed with symptomatic left PEA and ACD,respectively. The patients with left PEA had focal abdominal tenderness on the left lower quadrant(82.1%). On CT examination,most(89.3%) of the patients with left PEA were found to have an oval fatty mass with a hyperattenuated ring sign. In cases of left ACD,the patients presented with a more diffuse abdominal tenderness throughout the left side(52.0%vs 14.3%; P = 0.003). The patients with left ACD had fever and rebound tenderness more often than those with left PEA(40.0% vs 7.1%,P = 0.004; 52.0% vs14.3%,P = 0.003,respectively). Laboratory abnormalities such as leukocytosis were also more frequently observed in left ACD(52.0% vs 15.4%,P = 0.006).CONCLUSION:If patients have left-sided localized abdominal pain without associated symptoms or laboratory abnormalities,clinicians should suspect the diagnosis of PEA and consider a CT scan. | Jeong Ah Hwang Sun Moon Kim Hyun Jung Song Yu Mi Lee Kyung Min Moon Chang Gi Moon Hoon Sup Koo Kyung Ho Song Yong Seok Kim Tae Hee Lee Kyu Chan Huh Young Woo Choi Young Woo Kang Woo Suk Chung | 2013 | World Journal of Gastroenterology2013，19，40： | 6 |
| 3 | Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma according to baseline status: Subset analyses of the phase III Sorafenib Asia–Pacific trial显示文摘 | Ann-Lii Cheng Zhongzhen Guan Zhendong Chen Chao-Jung Tsao Shukui Qin Jun Suk Kim Tsai-Sheng Yang Won Young Tak Hongming Pan Shiying Yu Jianming Xu Fang Fang Jessie Zou Giuseppe Lentini Dimitris Voliotis Yoon-Koo Kang | 2011 | European Journal of Cancer2011，，10： | 4 |
| 4 | Effect of serum testosterone and percent tumor volume on extra-prostatic extension and biochemical recurrence after laparoscopic radical prostatectomy显示文摘几研究表明了外科手术前的浆液睾丸激素和百分比肿瘤体积(PTV ) 在激进的前列腺切除术以后预言 extra-prostatic 扩展(EPE ) 和生物化学的复发(BCR ) 。这研究在 laparoscopic 激进分子前列腺切除术(LRP ) 以后在与 EPE 和 BCR 的关系调查了浆液睾丸激素和 PTV 的预示的意义。我们考察了经历了在 2004 和 2012 之间的 LRP 的 520 个病人。PTV 在每节作为所有视觉上估计的肿瘤 foci 的和被决定。BCR 被定义为手术后的前列腺特定的抗原(PSA ) 的二连续增加 > 0.2 ng ml 1 。为浆液总数睾丸激素的阀值是 3.0 ng ml 1 。Multivariate 逻辑回归被用来在 EPE 和 BCR 的风险上定义变量的效果。低浆液睾丸激素(< 3.0 ng ml 1) 与高浆液 PSA,格利森分数,前列腺活体检视的积极核心百分比, PTV,和所有病理学的变量被联系。在 multivariate 分析上,类似于以前的研究,浆液 PSA,活体检视积极核心百分比,格利森分数,和病理学的变量预言了 EPE 和 BCR。另外,低浆液睾丸激素(< 3.0 ng ml 1 ,调整或, 8.52;95% CI, 5.04-14.4, P= 0.001 ) 预言的 EPE 和 PTV (调整或, 1.02;95% CI, 1.01-1.05, P= 0.046 ) 预言的 BCR。除了 EPE 和 BCR 的以前的预言者,低浆液睾丸激素和 PTV 在 LRP 以后是 EPE 和 BCR 的珍贵预言者。 | Eu Chang Hwang Seong Hyeon Yu Yang Hyun Jo Seung I1 Jung Taek Won Kang Dong Deuk Kwon Chan Choi Suk Hee Heo Jun Eul Hwang Sung-Hoon Jung Tae-Young Jung | 2016 | Asian Journal of Andrology2016，18，1： | 3 |
| 5 | Clinical characteristics of sibling patients with comitant strabismus显示文摘AIM:To investigate the clinical characteristics of sibling patients with comitant strabismus. METHODS:Sibling patients who were diagnosed with comitant strabismus from January 2005 to December 2014 were retrospectively reviewed. Factors including age, sex, types of strabismus, refractive errors, angle of deviation, and coexistence of other strabismus were analyzed. RESULTS:A total of 62 patients(31 pairs of siblings) were included. Of these, 26 pairs had intermittent exotropia, 3 had accommodative esotropia, and 2 had infantile esotropia. There were no pairs with different subtypes of strabismus. The age at first visit was 3.7±2.6y and the mean follow-up period was 30.5±24.1mo. In siblings with intermittent exotropia, there was no difference in age of onset, age at operation, or refractive errors between the first and second-born children. The 20(77%) pairs of siblings with exotropia showed more than 80% concordance of maximum angle of deviation during follow-up. In the 9 pairs in which both siblings had an operation, the final angle of deviation after the operation was 8.2±8.1 prism diopters(PD) in first-born children and 8.6±6.5 PD in second-born children. CONCLUSION:The subtypes of strabismus are the same in all pairs of siblings and clinical characteristics of strabismus are similar between the first and secondborn children. This similarity could be an indicator for the diagnosis of second-born children. Further prospective study including a larger number of sibling patients is needed. | Haeng Jin Lee Seong-Joon Kim Young Suk Yu | 2017 | International Journal of Ophthalmology(English edition)2017，10，5： | 2 |
| 6 | Usefulness of continuous renal replacement therapy for correcting hypernatremia in a patient with severe congestive heart failure显示文摘 | Hoon Suk Park Yu Ah Hong Hyun Gyung Kim Sun Ryoung Choi In O. Sun Byung Ha Chung Cheol Whee Park Chul Woo Yang Yong Soo Kim Bum Soon Choi | 2012 | Hemodial Int2012，，4： | 1 |
| 7 | Effect of corrosion method of the reinforcing bar on bond characteristics in rein- forced concrete specimens 显示文摘 | Yoon Suk Choi Seong-Tae Yi Myung Yu Kim | 2013 | Construction and Building Materials2013，，12： | 1 |
| 8 | Optical coherence tomographic finding in a case of macular coloboma显示文摘 | Joo Youn Oh MD Young Suk Yu MD | 2007 | Kor J Ophthalmol2007，21，3： | 1 |
| 9 | Surface properties of fluorinated oxetane polyol modified polyurethane block copolymers 显示文摘 | Yu - Seung Kim Jae - Suk Lee Qing Ji | 2002 | Polymer2002，43，25： | 1 |
| 10 | Financial development and economic growth: New evidence from panel data显示文摘 | KABIR M HASSAN BENITO SANCHEZ JUNG- SUK YU | 2011 | The Quarterly Review of E- conomics and Finance2011，51，1： | 1 |
| 11 | Variable phenotype of Pierson syndrome显示文摘 | Hyun Jin Choi Beom Hee Lee Ju Hyung Kang Hyoen Joo Jeong Kyung Chul Moon Il Soo Ha Young Suk Yu Verena Matejas Martin Zenker Yong Choi Hae Il Cheong | 2008 | Pediatric Nephrology2008，，6： | 1 |
| 12 | Direct GSK-3β Inhibition Enhances Mesenchymal Stromal Cell Migration by Increasing Expression of Beta-PIX and CXCR4显示文摘 | Young Seo Kim Min Young Noh Ji Young Kim Hyun-Jeung Yu Kyung Suk Kim Seung Hyun Kim Seong-Ho Koh | 2013 | Molecular Neurobiology2013，，2： | 1 |
| 13 | Fabrication of ordered uniform porous carbon networks and their application to a catalyst supporter显示文摘 | Jong Sung Yu Soonki Kang Suk Bon Yoon etal | 2002 | J Am Chem Soc2002，，124： | 1 |
| 14 | Global trends in Helicobacter pylori research from 1991 to 2008 analyzed with the Science Citation Index Expanded显示文摘 | Suk FM Lien GS Yu TC | 2011 | Eur J Gastroenterol Hepatol2011，23，4： | 1 |
| 15 | Inhibition of choroidal neovasularization by neovascularization by homeisoflavanone, a new angiogenesis inhibitor显示文摘 | Jeong Hun Kim Jin Hyoung Kim Young Suk Yu | 2008 | Mol Vis2008，14，： | 1 |
| 16 | Financial Development and Economic Growth: New Evidence from Panel Data显示文摘 | Kabir Hassan M Benito Sanchez Jung- Suk Yu | 2011 | The Quarterly Review of Economics and Finance2011，51，1： | 1 |
| 17 | Topographical Impact of Hepatitis B-related Hepatocellular Carcinoma on Local Recurrence After Radiofrequency Ablation显示文摘 | Joon Suk Kim Won Kim Young Ho So Su Jong Yu Byeong Gwan Kim | 2014 | Journal of Clinical Gastroenterology2014，，1： | 1 |
| 18 | Incidence and Clinical Features of Ethambutol-Induced Optic Neuropathy in Korea显示文摘 | Eun Ji Lee Seong-Joon Kim Ho Kyung Choung Jeong Hun Kim Young Suk Yu | 2008 | Journal of Neuro-Ophthalmology2008，，4： | 1 |
| 19 | TP53 codon 72 polymorphism associated with prognosis in patients with advanced gastric cancer treated with paclitaxel and cisplatin显示文摘 | Jong Gwang Kim Sang Kyun Sohn Yee Soo Chae Hong Suk Song Ki-Young Kwon Young Rok Do Min Kyoung Kim Kyung Hee Lee Myung Soo Hyun Won Sik Lee Chang-Hak Sohn Joo Seop Jung Gab Chul Kim Ho Young Chung Wansik Yu | 2009 | Cancer Chemotherapy and Pharmacology2009，，2： | 1 |
| 20 | Hepatitis B Virus X Protein Induces Hepatic Steatosis Via Transcriptional Activation of SREBP1 and PPARγ显示文摘 | Kook Hwan Kim Hye–Jun Shin Kyeongjin Kim Hyun Mi Choi Sang Hoon Rhee Hyung–Bae Moon Hyeong Hoe Kim Ung Suk Yang Dae–Yeul Yu Jaehun Cheong | 2007 | Gastroenterology2007，，5： | 1 |
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