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| 1 | Quality analysis of commercial samples of Ziziphi spinosae semen(suanzaoren) by means of chromatographic fingerprinting assisted by principal component analysis显示文摘Due to the scarcity of resources of Ziziphi spinosae semen(ZSS), many inferior goods and even adulterants are generally found in medicine markets. To strengthen the quality control, HPLC fingerprint common pattern established in this paper showed three main bioactive compounds in one chromatogram simultaneously. Principal component analysis based on DAD signals could discriminate adulterants and inferiorities. Principal component analysis indicated that all samples could be mainly regrouped into two main clusters according to the first principal component(PC1, redefined as Vicenin II)and the second principal component(PC2, redefined as zizyphusine). PC1 and PC2 could explain 91.42%of the variance. Content of zizyphusine fluctuated more greatly than that of spinosin, and this result was also confirmed by the HPTLC result. Samples with low content of jujubosides and two common adulterants could not be used equivalently with authenticated ones in clinic, while one reference standard extract could substitute the crude drug in pharmaceutical production. Giving special consideration to the well-known bioactive saponins but with low response by end absorption, a fast and cheap HPTLC methodfor quality control of ZSS was developed and the result obtained was commensurate well with that of HPLC analysis. Samples having similar fingerprints to HPTLC common pattern targeting at saponins could be regarded as authenticated ones. This work provided a faster and cheaper way for quality control of ZSS and laid foundation for establishing a more effective quality control method for ZSS. | Shuai Sun Hailing Liu Shunjun Xu Yuzhen Yan Peishan Xie | 2014 | Journal of Pharmaceutical Analysis2014，4，3： | 17 |
| 2 | Small RNA Profiling Reveals Phosphorus Deficiency as a Contributing Factor in Symptom Expression for Citrus Huanglongbing Disease显示文摘Huanglongbing (HLB ) 是与类 Candidatus Liberibacter 的细菌被联系的破坏柠檬疾病(Ca。L.) 。强大的诊断工具和管理策略被需要控制 HLB。小 RNA (sRNA ) 玩的主人在调整主人回答到病原体感染的一个重要角色并且为许多人的疾病被用作早诊断的标记,包括癌症。决定是否柠檬 sRNAs 调整主人回答到 HLB, sRNAs 从柠檬 sinensis 被介绍有 Ca 的 10 和 14 星期柱子 grafting。L。asiaticus (Las ) 积极或健康的织物。十新 microRNAs (miRNAs ) , 76 保存 miRNAs,和许多小介入 RNA (siRNAs ) 被发现。几 miRNAs 和 siRNAs 被 Las 感染高度导致,并且能潜在地被开发进 HLB 的早诊断标记。miR399,被磷饥饿在另外的植物种类导致,被与类似于 HLB 的症状引起柠檬 stubborna 疾病的 Las 然而并非 Spiroplasma citri 的感染明确地导致。我们与健康的树相比在 Las 积极的柠檬树上发现了磷的 35% 减小。HLB 积极的香甜的橘子树的适用的磷 oxyanion 答案减少了 HLB 症状严厉并且显著地在西南佛罗里达在 3 年的地试用期间改进了水果生产。我们的分子,生理,并且地数据建议那磷缺乏被连接到 HLB 疾病 symptomology。 | Hongwei Zhao Ruobai Sun Ute Albrecht Chellappan Padmanabhan Airong Wanga Michael D. Coffey Thomas Girke Zonghua Wang Timothy J. Close Mikeal Roose Raymond K. Yokomi Svetlana Folimonova Georgios Vidalakis Robert Rouse Kim D. Bowman Hailing Jin | 2013 | Molecular Plant2013，6，2： | 12 |
| 3 | Investigation into the Formation, Structure, and Evolution of an EF4 Tornado in East China Using a High-Resolution Numerical Simulation显示文摘Devastating tornadoes in China have received growing attention in recent years, but little is known about their formation, structure, and evolution on the tornadic scale. Most of these tornadoes develop within the East Asian monsoon regime, in an environment quite different from tornadoes in the U.S. In this study, we used an idealized, highresolution(25-m grid spacing) numerical simulation to investigate the deadly EF4(Enhanced Fujita scale category 4)tornado that occurred on 23 June 2016 and claimed 99 lives in Yancheng, Jiangsu Province. A tornadic supercell developed in the simulation that had striking similarities to radar observations. The violent tornado in Funing County was reproduced, exceeding EF4(74 ms–1), consistent with the on-site damage survey. It was accompanied by a funnel cloud that extended to the surface, and exhibited a double-helix vorticity structure. The signal of tornado genesis was found first at the cloud base in the pressure perturbation field, and then developed both upward and downward in terms of maximum vertical velocity overlapping with the intense vertical vorticity centers. The tornado's demise was found to accompany strong downdrafts overlapping with the intense vorticity centers. One of the interesting findings of this work is that a violent surface vortex was able to be generated and maintained, even though the simulation employed a free-slip lower boundary condition. The success of this simulation, despite using an idealized numerical approach, provides a means to investigate more historical tornadoes in China. | Dan YAO Haile XUE Jinfang YIN Jisong SUN Xudong LIANG Jianping GUO | 2018 | Journal of Meteorological Research2018，32，2： | 10 |
| 4 | On the Kinematic Characteristics and Dynamic Process of Boundary faults of the Nansha Ultra-crust Layer-Block显示文摘The Nansha ultra-crust layer-block is confined by ultra-crustal boundary faults of distinctive features, bordering the Kangtai-Shuangzi-Xiongnan extensional faulted zone on the north, the Baxian-Baram-Yoca-Cuyo nappe faulted zone on the south, the Wan’an-Natuna strike-slip tensional faulted zone on the west and the Mondoro-Panay strike-slip compressive faulted zone on the east. These faults take the top of the Nansha asthenosphere as their common detachmental surface. The Cenozoic dynamic process of the ultra-crust layer-block can be divided into four stages: K2-E21, during which the northern boundary faults extended, this ultra-crust layer-block was separated from the South China-Indosinian continental margin, the Palaeo-South China Sea subducted southwards and the Sibu accretion wedge was formed; E22-E31, during which the Southwest sub-sea basin extended and orogeny was active due to the collision of the Sibu accretion wedge; E32-N11, during which the central sub-sea basin extended, the Miri | LIU Hailing SUN Yan GUO Lingzhi SHU Liangshu YANG Shukang ZHOU Di ZHANG Yixiang | 1999 | Acta Geologica Sinica(English Edition)1999，73，4： | 9 |
| 5 | Atomically thin defect-rich Ni-Se-S hybrid nanosheets as hydrogen evolution reaction electrocatalysts显示文摘Facile design of economic-effective hydrogen evolution reaction(HER)catalysts with non-noble materials are promising for the production of renewable chemical fuels.Two-dimensional(2D)ultrathin transition metal dichalcogenides(TMDs)materials with large specific surface area and abundant catalytic active sites can significantly enhance their catalytic activities.Herein,we design and synthesize an atomically thin Ni-Se-S based hybrid nanosheet(NiSe1.2S0.8)via a simple solvothermal method,the thickness of NiSe1.2S0.8 nanosheets is only about 1.1 nm.Benefiting from the ultrathin nanostructure and rich defects,the optimal NiSe1.2S0.8 exhibits good electrocatalytic activity with the overpotential of 144 mV at−10 mA·cm−2,a small Tafel slope of 59 mV·dec−1,and outstanding catalytic stability in acid electrolyte for HER.The theoretical results show that hybrid electrocatalyst by S incorporation possesses the optimal adsorption free energy of hydrogen(ΔGH*).This study provides a simple method to synthesize a highperformance multicomponent electrocatalysts with the ultrathin nanostructures and abundant defects. | Jianpeng Sun Xiangting Hu Zhaodi Huang Tianxiang Huang Xiaokang Wang Hailing Guo Fangna Dai Daofeng Sun | 2020 | Nano Research2020，13，8： | 5 |
| 6 | Enhanced catalysis of ultrasmall Au-MoS_2 clusters against reactive oxygen species for radiation protection显示文摘Ionizing radiation produces excessive reactive oxygen species(ROS) which impose detrimental effects on biological systems. Thus, it is important to explore clinically safe and efficacious radioprotection agents to scavenge ROS and reduce the risks of radiotherapy. Recently, emerging catalytic nanomaterials such as sulfide nanomaterials have shown capability of clearing ROS in vivo by unique electron transfers between atoms, but their catalytic activities are yet suboptimal. As such, there is an unmet need to improve catalytic properties for stronger antioxidant activities and radiation protection. Herein, we prepared ultrasmall Au-MoS_2 clusters(~2.5 nm) and they showed enhanced catalytic properties via gold intercalation facilitating increased active sites and synergistic effects. Electrocatalysis results revealed that the catalytic activity of Au-MoS_2 towards H2O_2 was superior to ultrasmall MoS_2 without Au. As a result, we found that improving the electrocatalytic property of Au-MoS_2 can effectively enhance corresponding antioxidant activities and radioprotection effects in vivo. In addition, Au-MoS_2 also showed significant radioprotection in vitro and dramatically reduced the excess of radiation-induced adverse ROS. It also rescued radiation-induced DNA damages and protected the bone marrow hematopoietic system from ionizing radiation. | Peixian Bian Jinxuan Zhang Junying Wang Jiang Yang Jingya Wang Haile Liu Yuanming Sun Meixian Li Xiao-Dong Zhang | 2018 | Science Bulletin2018，63，14： | 2 |
| 7 | Study of the aerostatic and aerodynamic stability of super long-span cable-stayed bridges显示文摘With the increase of span length,the bridge tends to be more flexible,and the wind stability becomes an important problem for the design and construction of super long-span cable-stayed bridges. By taking a super long-span cable-stayed bridge with a main span of 1 400 m as example,the aerostatic and aerodynamic stability of the bridge are investigated by three-dimensional nonlinear aerostatic and aerodynamic stability analysis,and the results are compared with those of a suspension bridge with a main span of 1 385 m,and from the aspect of wind stability,the feasibility of using cable-stayed bridge in super long-span bridge with a main span above 1 000 m is discussed. In addition,the influences of design parameters including the depth and width of the girder,the tower structure,the tower height-to-span ratio,the side-to-main span ratio,the auxiliary piers in the side span and the anchorage system of stay cables,etc on the aerostatic and aerodynamic stability of super long-span cable-stayed bridges are investigated numerically;the key design parameters are pointed out,and also their reasonable values are proposed. | Zhang Xinjun Sun Hailing | 2014 | Engineering Sciences2014，12，2： | 2 |
| 8 | Apoptosis as a novel target for cancer chemoprevention显示文摘 | Sun SY Hail N Jr Lotan R | 2004 | J Natl Cancer Inst2004，96，9： | 1 |
| 9 | Apoptosis as a novel target for cancer chemoprevention 显示文摘 | Sun SY Hail N Jr Lotan R | 2004 | J Natl Cancer lnst2004，96，9： | 1 |
| 10 | Ligand controlled structure of cadmium(Ⅱ) metal-organic frameworks for fluorescence sensing of Fe^(3+) ion and nitroaromatic compounds显示文摘Three cadmium(II) metal-organic frameworks(MOFs) based on tetracarboxylate ligands, namely[Cd_2(TTTA)(DMF)_3]·2 DMF(1),[Cd_2(TB)(H_2O)_4]·3DMF·H_2O(2)and [Cd(TEB)_(0.5)].2 DMF.4 H_2O(3) have been designed and synthesized. Complex 1 is a 2-dimensional(2 D) 3,4-connected network with 3,4 L13 topology, complex 2 features a 3-dimensional(3D) 3,4-connected tfa topology with a 2-fold interpenetrating structure and complex 3 has a 3D 4-connected dia topology with a 4-fold interpenetrating structure. Interestingly, 2 exhibits permanent pores and selective adsorption of CO_2 over CH_4. In addition, 2 shows fluorescence sensing of Fe^(3+) ion and rapid detection of nitroaromatic compounds(NACs) through fluorescence quenching. | Xia Wang Weidong Fan Ming Zhang Yizhu Shang Yutong Wang Di Liu Hailing Guo Fangna Dai Daofeng Sun | 2019 | Chinese Chemical Letters2019，30，3： | 1 |
| 11 | Apoptosis as a novel target for cancer chemoprevention显示文摘 | Sun SY Hail N Jr Lotan R | 2004 | J Natl Cancer Inst2004，96，9： | 1 |
| 12 | Preparation and electrochemical characterization of slngle-crystalline spherical LiNi1/3 Co1/3 Mnv30z pow- ders cathode material for Li-ion batteries显示文摘 | Xiaoyan Hail Qingfei Meng Taolei Sun | 2010 | J Power Sources2010，19，： | 1 |
| 13 | Apoptosis as a novel target for cancer chemoprevention 显示文摘 | Sun S Y Hail N J Lotan R | 2004 | J Nat Cancer Inst2004，96，9： | 1 |
| 14 | Ultrasonic-assisted enzymatic degradation of cholecterol in egg yolk 显示文摘 | Yan Sun Hailing Yang Xueming Zhong | 2011 | Innovative Food Science and Emerging Technologies2011，12，： | 1 |
| 15 | Apoptosis as a novel target for cancer chemoprevention显示文摘 | Sun SY Hail N Lotan R | 2004 | J Natl Cancer lnst2004，96，9： | 1 |
| 16 | High brightness NIR-Ⅱ nanofluorophores based on fused-ring acceptor molecules显示文摘It is challenging to develop molecular fluorophores in the second near-infrared(NIR-Ⅱ)window with long wavelength emission and high brightness,which can improve the performance of biological imaging.Herein,we report a molecular engineering approach to afford NIR-Ⅱ fluorophores with these merits based on fused-ring acceptor(FRA)molecules.Dioctyl 3,4-propylenedioxy thiophene(PDOT-C8)is utilized as the bridging donor to replace 3-ethylhexyloxy thiophene(3-EHOT),leading to more than 20 times enhancement of brightness.The nanofluorophores(NFs)based on the optimized CPTIC-4F molecule exhibit an emission peak of 1,110 nm with a fluorescence quantum yield(QY)of 0.39%(QY of IR-26 is 0.050%in dichloroethane as reference)and peak absorption coefficient of 14.5 x 10^4 M^-1·cm^-1 in aqueous solutions,which are significantly higher than those of 3-EHOT based COTIC-4F NFs.It is found that PDOT-C8 can weaken intermolecular aggregation,enhance protection of molecular backbone from water,and decrease backbone distortion,beneficial for the high brightness.Compared with indocyanine green with same injection dose,CPTIC-4F NFs show 10 times higher signal-to-background ratio for whole body vessels imaging at 1,300 nm long pass filters. | Xingfu Zhu Chunchen Liu Zhubin Hu Haile Liu Jiang Wang Yang Wang Xinyuan Wang Rui Ma Xiaodong Zhang Haitao Sun Yongye Liang | 2020 | Nano Research2020，13，9： | 1 |
| 17 | Overexpression of PvWOX3a in switchgrass promotes stem development and increases plant height显示文摘Switchgrass(Panicum virgatum L.)is an important perennial,noninvasive,tall ornamental grass that adds color and texture to gardens and landscapes.Moreover,switchgrass has been considered a forage and bioenergy crop because of its vigorous growth,low-input requirements,and broad geography.Here,we identified PvWOX3a from switchgrass,which encodes a WUSCHEL-related homeobox transcription factor.Transgenic overexpression of PvWOX3a in switchgrass increased stem length,internode diameter,and leaf blade length and width,all of which contributed to a 95%average increase in dry weight biomass compared with control plants.Yeast one-hybrid and transient dual-luciferase assays showed that PvWOX3a can repress the expression of gibberellin 2-oxidase and cytokinin oxidase/dehydrogenase through apparently direct interaction with their promoter sequences.These results suggested that overexpression of PvWOX3a could increase gibberellin and cytokinin levels in transgenic switchgrass plants,which promotes cell division,elongation,and vascular bundle development.We also overexpressed PvWOX3a in a transgenic miR156-overexpressing switchgrass line that characteristically exhibited more tillers,thinner internodes,and narrower leaf blades.Double transgenic switchgrass plants displayed significant increases in internode length and diameter,leaf blade width,and plant height but retained a tiller number comparable to that of plants expressing miR156 alone.Ultimately,the double transgenic switchgrass plants produced 174%more dry-weight biomass and 162%more solubilized sugars on average than control plants.These findings indicated that PvWOX3a is a viable potential genetic target for engineering improved shoot architecture and biomass yield of horticulture,fodder,and biofuel crops. | Ruijuan Yang Zhenying Wu Chen Bai Zhichao Sun Mengqi Wang Yuzhu Huo Hailing Zhang Yamei Wang Huapeng Zhou Shaojun Dai Wenwen Liu Chunxiang Fu | 2021 | Horticulture Research2021，8，1： | 1 |
| 18 | Apoptosis as a novel target for cancer chemoprevention显示文摘 | Sun S Y Hail N Jr Lotan R | 2004 | J Natl Cancer Inst2004，96，9： | 1 |
| 19 | Apoptosis as a Novel target for cancer Chemprevention 显示文摘 | Sun SY Hail N Jr lotan R | 2004 | J Nail Cancer Inst2004，96，9： | 1 |
| 20 | Isolation and characterization of collagen from the cartilage of Amur sturgeon ( Acipenser schrenckii )显示文摘 | Qiufang Liang Lin Wang Weihong Sun Zhenbin Wang Junmin Xu Haile Ma | 2013 | Process Biochemistry2013，，： | 1 |
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