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| 1 | 外语能力磨蚀的性别差异初探显示文摘对300余名大学生进行了英语阅读和听力测试,并从中随机抽取男女生各50名进行了写作测试,得出如下结论:(1)外语磨蚀程度存在明显的性别差异;(2)男女生在深度阅读、短对话听力以及段落听力方面的磨蚀差异不显著;(3)女生在快速阅读能力方面的磨蚀程度明显超过男生;(4)女生写作能力在切题性、连贯性以及清楚性方面的磨蚀程度显著大于男生,而在语言的正确性方面的磨蚀没有明显超过男生。 | 于中根 Chan Swee Heng Ain Nadzimah Bt Abdullah Bahaman bin Abu Samah Yap Ngee Thai | 2010 | 南京邮电大学学报(社会科学版)2010，12，2： | 19 |
| 2 | Transparent, stretchable, and rapid-response humidity sensor for body-attachable wearable electronics显示文摘能为连续地在人的身体或潮湿附近监视环境的湿度被纳入人的身体的可拉长、保角的湿度传感器人的皮肤铺平能在电子皮肤和个人保健应用程序起一个重要作用。然而,很可拉长的湿度传感器基于 non-stretchable 部件的几何工程,仅仅一些详细研究在在应用机械变丑下面的可拉长的湿度传感器上是可得到的。在这份报纸,我们与一个简单制造过程建议一个透明、可拉长的湿度传感器,有提供与快反应和松驰时间一起的高 stretchability,敏感,和稳定性的内在地可拉长的部件。减少的 graphene 氧化物聚氨酯 composites 和一个弹性体的传导性的电极镇静,这台设备分别地象 3.5 和 7 s 一样快展出出色的反应和松驰时间。responsivity 和反应和松驰面对在拉长直到 60% 并且在 10,000 以后的紧张下面几乎未改变的湿度遗体设备预定在 40% 紧张拉长周期。进一步,这些可拉长的湿度传感器能容易并且保角地为在人的身体,湿目标,或人的皮肤附近监视环境的湿度层次被纳入一根手指。 | Tran Quang Trung Le Thai Duy Subramanian Ramasundaram Nae-Eung Lee | 2017 | Nano Research2017，10，6： | 15 |
| 3 | A hybrid machine learning ensemble approach based on a Radial Basis Function neural network and Rotation Forest for landslide susceptibility modeling:A case study in the Himalayan area, India显示文摘In this paper, a hybrid machine learning ensemble approach namely the Rotation Forest based Radial Basis Function(RFRBF) neural network is proposed for spatial prediction of landslides in part of the Himalayan area(India). The proposed approach is an integration of the Radial Basis Function(RBF) neural network classifier and Rotation Forest ensemble, which are state-of-the art machine learning algorithms for classification problems. For this purpose, a spatial database of the study area was established that consists of 930 landslide locations and fifteen influencing parameters(slope angle, road density, curvature, land use, distance to road, plan curvature, lineament density, distance to lineaments, rainfall,distance to river, profile curvature, elevation, slope aspect, river density, and soil type). Using the database, training and validation datasets were generated for constructing and validating the model. Performance of the model was assessed using the Receiver Operating Characteristic(ROC) curve, area under the ROC curve(AUC), statistical analysis methods, and the Chi square test. In addition, Logistic Regression(LR), Multi-layer Perceptron Neural Networks(MLP Neural Nets), Na(?)ve Bayes(NB), and the hybrid model of Rotation Forest and Decision Trees(RFDT) were selected for comparison. The results show that the proposed RFRBF model has the highest prediction capability in comparison to the other models(LR, MLP Neural Nets, NB, and RFDT); therefore, the proposed RFRBF model is promising and should be used as an alternative technique for landslide susceptibility modeling. | Binh Thai Pham Ataollah Shirzadi Dieu Tien Bui Indra Prakash M.B.Dholakia | 2018 | International Journal of Sediment Research2018，33，2： | 14 |
| 4 | 基于稳健统计学和EDA技术的地球化学异常下限确定显示文摘当地球化学数据并不服从正态分布或对数正态分布,甚至连数据转换之后也不服从正态分布时,很难用传统的方法进行统计分析。这里以一个具体的地区为例,应用了基于稳健统计学和EDA技术的地球化学异常下限确定方法,其具有简单和'稳健'的特点,也不要求数据服从任何分布。通过比较分析了基于稳健统计学和EDA技术的地球化学异常下限确定方法与传统方法的优缺点。实践表明,用该方法圈定的地球化学异常符合客观实际,异常范围大,与已知矿床(点)吻合很好。 | Nguyen Tien Thanh 刘修国 陈春亮 任泽 Dang Thai Son | 2013 | 物探化探计算技术2013，35，3： | 12 |
| 5 | Bi和Sr改性Al-7Si-0.4Mg合金显微组织的影响(英文)显示文摘研究单独添加Bi和联合添加Bi与Sr在不同凝固条件下对Al-7Si-0.4Mg合金中共晶硅结构的影响。结果表明:添加Bi对共晶硅有细化作用,其细化能力随着Bi质量分数(在<0.5%范围内)的增加而增强。当Bi添加到Sr改性的合金中时,为了得到充分的共晶硅改性,较高的Sr/Bi质量比(至少0.45)是必要的。 | S. FARAHANY A. OURDJINI M. H. IDRIS L. T. THAI | 2011 | Transactions of Nonferrous Metals Society of China2011，21，7： | 7 |
| 6 | Gut microbiota,inflammatory bowel disease and colorectal cancer显示文摘The gut microbiota is a complex community of microorganisms that inhabit the digestive tracts of humans,living in symbiosis with the host.Dysbiosis,characterized by an imbalance between the beneficial and opportunistic gut microbiota,is associated with several gastrointestinal disorders,such as irritable bowel syndrome(IBS);inflammatory bowel disease(IBD),represented by ulcerative colitis and Crohn’s disease;and colorectal cancer(CRC).Dysbiosis can disrupt the mucosal barrier,resulting in perpetuation of inflammation and carcinogenesis.The increase in some specific groups of harmful bacteria,such as Escherichia coli(E.coli)and enterotoxigenic Bacteroides fragilis(ETBF),has been associated with chronic tissue inflammation and the release of pro-inflammatory and carcinogenic mediators,increasing the chance of developing CRC,following the inflammationdysplasia-cancer sequence in IBD patients.Therefore,the aim of the present review was to analyze the correlation between changes in the gut microbiota and the development and maintenance of IBD,CRC,and IBD-associated CRC.Patients with IBD and CRC have shown reduced bacterial diversity and abundance compared to healthy individuals,with enrichment of Firmicute sand Bacteroidetes.Specific bacteria are also associated with the onset and progression of CRC,such as Fusobacterium nucleatum,E.coli,Enterococcus faecalis,Streptococcus gallolyticus,and ETBF.Future research can evaluate the advantages of modulating the gut microbiota as preventive measures in CRC high-risk patients,directly affecting the prognosis of the disease and the quality of life of patients. | Ana Elisa Valencise Quaglio Thais Gagno Grillo Ellen Cristina Souza De Oliveira Luiz Claudio Di Stasi Ligia Yukie Sassaki | 2022 | World Journal of Gastroenterology2022，28，30： | 7 |
| 7 | Single-operator, single-session EUS-guided anterograde cholangiopancreatography in failed ERCP or inaccessible papilla显示文摘 | Janak N. Shah Fernando Marson Frank Weilert Yasser M. Bhat Thai Nguyen-Tang Richard E. Shaw Kenneth F. Binmoeller | 2012 | Gastrointestinal Endoscopy2012，，1： | 5 |
| 8 | 东南亚断裂构造的演化(英文)显示文摘本研究项目是采用诸如地质学解释、影像判读和地球物理探测等多种方法相结合进行的。在所得结果 的基础上参考了越南国内外同行的一些资料编制了东南亚、越南及邻区的断裂构造图,其比例尺分别为1∶4百万 和1∶1百万。分析所得结果显示出东南亚断裂构造演化的下列情况: 1)在现今地质结构方面 东南亚是欧亚岩石圈板块的东南部分,由一条消减带围绕,这条消减带的伸展从 Myanmer开始,通过Nicobar,JavaTimor直到东菲律宾。东南亚被SongHong(即红河)断裂,ThreePagodas断裂 和Hainam Natuna断裂等2级断裂系统分成3个微板块。 2)在早新生代,东南亚是分为5个微板块的。它们的分界断裂中有2个一级断裂(中央东海扩张带和Lupar Kuching消减带)和3个二级断裂(即上述3个)。 3)上述绝大多数二和三级断裂从晚新生代起活化且继承了从早新生代即已发生和发展了的二、三级断裂,但 在某些条件下,运动方向却完全变成了相反,尤其是走滑运动的方向。我们的研究结果表明:在这一地区内,盆地、 隆起、岩浆侵入、褶皱和局部断裂等构造的形成都取决于这些沿着一、二级走滑断裂的微板块运动。 | 高庭朝 阮友宣 黎文勇 范南雄 Mai Xuan Bach Thai Anh Tuan | 2005 | 大地测量与地球动力学2005，25，1： | 5 |
| 9 | Novel fibrin-fibronectin matrix accelerates mice skin wound healing显示文摘Plasma fibrinogen(F1)and fibronectin(pFN)polymerize to form a fibrin clot that is both a hemostatic and provisional matrix for wound healing.About 90%of plasma F1 has a homodimeric pair ofγchains(γγF1),and 10%has a heterodimeric pair ofγand more acidicγ′chains(γγ′F1).We have synthesized a novel fibrin matrix exclusively from a 1:1(molar ratio)complex ofγγ′F1 and pFN in the presence of highly active thrombin and recombinant Factor XIII(rFXIIIa).In this matrix,the fibrin nanofibers were decorated with pFN nanoclusters(termedγγ′F1:pFN fibrin).In contrast,fibrin made from 1:1 mixture ofγγF1 and pFN formed a sporadic distribution of“pFN droplets”(termedγγF1+pFN fibrin).Theγγ′F1:pFN fibrin enhanced the adhesion of primary human umbilical vein endothelium cells(HUVECs)relative to theγγF1+FN fibrin.Three dimensional(3D)culturing showed that theγγ′F1:pFN complex fibrin matrix enhanced the proliferation of both HUVECs and primary human fibroblasts.HUVECs in the 3Dγγ′F1:pFN fibrin exhibited a starkly enhanced vascular morphogenesis while an apoptotic growth profile was observed in theγγF1+pFN fibrin.Relative toγγF1+pFN fibrin,mouse dermal wounds that were sealed byγγ′F1:pFN fibrin exhibited accelerated and enhanced healing.This study suggests that a 3D pFN presentation on a fibrin matrix promotes wound healing. | Carlos Poblete Jara Ou Wang Thais Paulino do Prado Ayman Ismail Frank Marco Fabian Han Li Licio A.Velloso Mark A.Carlson William Burgess Yuguo Lei William H.Velander Eliana P.Araújo | 2020 | Bioactive Materials2020，5，4： | 5 |
| 10 | Double-loop Control Structure Using Proportional Resonant and Sequence-decoupled Resonant Controllers in Static Coordinates for Dynamic Voltage Restorer显示文摘Among incidents on grids,the sag/swell voltage is considered as the most frequent incident.To solve this problem,custom power devices are used.In particular,the dynamic voltage restorer(DVR)is a modern and efficient customer device.DVRs are used to mitigate voltage sag/swells and harmonics on the load bus,thus protecting the sensitive loads.The DVR is a serial compensator that applies a voltage to the point of common coupling to maintain the voltage of sensitive load at the nominal value.To improve the performance of DVRs,in this study,the control strategy of the two-stage loop circuit is implemented.The external voltage control loop uses a sequence-decoupled resonant(SDR)controller,and the inner current-control loop uses the proportional resonant(PR)controller implemented in the stationary frameαβ. | Vu Thai Hung Hongchun Shu Le Ngoc Giang Nguyen Duc The | 2019 | Chinese Journal of Electrical Engineering2019，5，3： | 4 |
| 11 | 新型器官保存液低温保存猪小肠的实验研究显示文摘目的探讨Lifor器官保存液对猪小肠的低温保存效果。方法 24只白色杂种猪,随机分成Lifor液组和威斯康星大学保存液(University of Wisconsin solution,UW液)组,分别采用4℃的Lifor液和UW液灌洗并低温保存移植小肠,每组再根据供肠保存时间的不同随机分成两个亚组,分别为保存6h、9h组,每个亚组6只动物。建立猪自体节段性小肠移植模型。比较低温保存小肠结束时Lifor液组和UW液组小肠黏膜的组织病理学及三磷腺苷(ATP)含量的改变,并测定移植小肠造口输注麦芽糖后各时间点的血糖水平,观察移植后小肠吸收功能情况。结果供肠保存6h和9h后,Lifor液组与UW液组的小肠组织病理学改变基本一致,比较差异无统计学意义(均为P>0.05),保存9h的小肠黏膜形态异常,损伤较保存6h的小肠黏膜严重。供肠保存6h和9h后,Lifor液组与UW液组的小肠黏膜ATP含量比较差异无统计学意义(均为P>0.05),小肠黏膜的ATP含量随保存时间的延长逐渐降低。移植后7、14d两组小肠吸收功能差异亦无统计学意义(P>0.05)。结论 Lifor液低温保存小肠的效果与UW液相当,且成本低廉,具有一定的临床应用前景。 | 郭明晓 李幼生 王志梁 THAI Ngoc L 黎介寿 | 2013 | 器官移植2013，4，1： | 4 |
| 12 | Toll-like receptor 9 is correlated to disease activity in Chinese systemic lupus erythematosus population显示文摘 | MU Rong SUN Xiao-yun Lik Thai Lim XU Chuan-hui DAI Chen-xian SU Yin JIA Ru-lin LI Zhan-guo | 2012 | Chinese Medical Journal2012，，16： | 3 |
| 13 | Phosphomonoester Phosphoethanolamine Induces Apoptosis in Human Chronic Myeloid Leukemia Cells显示文摘Background:Leukemia is a type of cancer that starts in the blood or blood-forming tissues.It results from the clonal proliferation of hematopoietic cells in the bone marrow and/or lymphoid tissues,which subsequently reach the peripheral circulation and can infiltrate other systems.There are many different kinds of leukemia,and treatments are different for each one.Chronic leukemia is with a slower growing than acute leukemia but could be just as life-threatening.Phospholipids are antitumor analogs,such as synthetic phosphoethanolamine,which is a phosphorylated compound capable of controlling cellular proliferation and inducing apoptosis in several types of tumor cells.Methods:K562 and K562-Lucena(MDR+)human chronic myeloid leukemia cells were treated with synthetic phosphoethanolamine(Pho-s).The viability was evaluated by sulforhodamine B(SRB)assay and cell cycle phases,apoptosis,markers expression,and mitochondrial potential were assessed by flow cytometry.Results:Tumor cells formed clusters in suspension and decreased significantly viability.The concentrations for IC50%were obtained.Pho-s treated were 43.1 mM(K562)and 145.9 mM(K562-Lucena MDR+)in a period of 24 hours.Pho-s induced changes in the distribution of cell population phases of cell cycle which showed an increase in fragmented DNA and increased markers expression envolved apoptosis pathways a decrease in the G1/G0 phase.Discussion:Treatment of K562 and K562-Lucena(MDR+)chronic myeloid leukemia cells with Pho-s showed dose and time dependent cytotoxic effects.This cytotoxicity induced a decrease in proliferative capacity,mitochondrial electrical potential,and consequently release of cytochrome C;inhibition of Bcl-2 family protein expression,increase in pro-apoptotic family members Bad and Bax,dependent on p53 expression.Conclusion:This study presented a significant therapeutic potential of Phos-s in this type of leukemia through the apoptotic effects on tumor cells independently of the molecular resistance profile(MDR+). | Thais de Oliveira Conceicao Manuela Garcia Laveli da Silva Durvanei Augusto Maria | 2019 | Journal of Pharmacy and Pharmacology2019，7，7： | 3 |
| 14 | Operation Strategies for Coordinating Battery Energy Storage with Wind Power Generation and Their Effects on System Reliability显示文摘The variability of wind power generation requires the allocation of a flexible energy reserve which is capable of compensating for possible imbalances between the load and generation. To reduce the variability of wind power generation and loss of load in generation deficit, we propose operation strategies for coordinating battery energy storage with wind power generation. The effects of the operation strategies on system reliability are evaluated by the developed computation model that represents the main aspects and operation limitations of the batteries. The performance evaluation of the power system is based on the composite reliability indices of loss of load probability(LOLP) and expected energy not supplied(EENS), which is calculated through sequential Monte Carlo simulation. Tests are performed by the developed model with a tutorial system consisting of five busbars and the IEEE RTS system. The results show that the use of large-scale batteries is an alternative to physically guarantee the wind power plants and to act as an operation reserve to reduce the risk of loss of load. | Thais P.Teixeira Carmen L.T.Borges | 2021 | Journal of Modern Power Systems and Clean Energy2021，9，1： | 2 |
| 15 | MicroRNA expression in inflammatory bowel disease-associated colorectal cancer显示文摘MicroRNAs(miRNAs)are non-coding RNA molecules composed of 19–25 nucleotides that regulate gene expression and play a central role in the regulation of several immune-mediated disorders,including inflammatory bowel diseases(IBD).IBD,represented by ulcerative colitis and Crohn’s disease,is characterized by chronic intestinal inflammation associated with an increased risk of colorectal cancer(CRC).CRC is one of the most prevalent tumors in the world,and its main risk factors are obesity,physical inactivity,smoking,alcoholism,advanced age,and some eating habits,in addition to chronic intestinal inflammatory processes and the use of immunosuppressants administered to IBD patients.Recent studies have identified miRNAs associated with an increased risk of developing CRC in this population.The identification of miRNAs involved in this tumorigenic process could be useful to stratify cancer risk development for patients with IBD and to monitor and assess prognosis.Thus,the present review aimed to summarize the role of miRNAs as biomarkers for the diagnosis and prognosis of IBD-associated CRC.In the future,therapies based on miRNA modulation could be used both in clinical practice to achieve remission of the disease and restore the quality of life for patients with IBD,and to identify the patients with IBD at high risk for tumor development. | Thais Gagno Grillo Ana Elisa Valencise Quaglio Rodrigo Fedatto Beraldo Talles Bazeia Lima Julio Pinheiro Baima Luiz Claudio Di Stasi Ligia Yukie Sassaki | 2021 | World Journal of Gastrointestinal Oncology2021，13，9： | 2 |
| 16 | Hepatocellular carcinoma with child Pugh-A Cirrhosis treated with stereotactic body radiotherapy显示文摘AIM To evaluate the control, survival, and hepatic function for Child Pugh(CP)-A patients after Stereotactic body radiotherapy(SBRT) in hepatocellular carcinoma(HCC).METHODS From 2009 to 2016, 40 patients with Barcelona Liver Clinic(BCLC) stages 0-B HCC and CP-A cirrhosis completed liver SBRT. The mean prescription dose was 45 Gy(40 to 50 Gy in 4-5 fractions). Local relapse, defined as recurrence within the planning target volume was assessed with intravenous multiphase contrast computed tomography or magnetic resonance imaging every 4-6 mo after completion of SBRT. Progression of cirrhosis was evaluated by CP and Model for End Stage Liver Disease scores every 3-4 mo. Toxicities were graded per the Common Terminology Criteria for Adverse Events(v4.03). Median follow-up was 24 mo.RESULTS Forty-nine HCC lesions among 40 patients were analyzed in this IRB approved retrospective study. Median tumor diameter was 3.5 cm(1.5-8.9 cm). Six patients with tumors ≥ 5 cm completed planned selected transarterial chemoembolization(TACE) in combination with SBRT. Eight patients underwent orthotropic live transplant(OLT) with SBRT as a bridging treatment(median time to transplant was 12 mo, range 5 to 23 mo). The Pathologic complete response(PCR) rate in this group was 62.5%. The 2-year in-field local control was 98%(1 failure). Intrahepatic control was 82% and 62% at 1 and 2 years, respectively. Overall survival(OS) was 92% and 60% at 1 and 2 years, with a median survival of 41 mo per Kaplan Meier analysis. At 1 and 2 years, 71% and 61% of patients retained CPA status. Of the patients with intrahepatic failures, 58% developed progressive cirrhosis, compared to 27% with controlled disease(P = 0.06). Survival specific to hepatic failure was 92%, 81%, and 69% at 12, 18, and 24 mo. There was no grade 3 or higher toxicity. On univariate analysis, gross tumor volume(GTV) < 23 cc was associated with freedom from CP progression(P = 0.05), hepatic failure-specific survival(P = 0.02), and trended with OS(P = 0.10).CONCLUSION SBRT is safe and effective in HCC with early cirrhosis and may extend waiting time for transplant in patients who may not otherwise be immediate candidates. | Shaakir Hasan Ngoc Thai Tadahiro Uemura Vijay Kudithipudi Paul Renz Stephen Abel Alexander V Kirichenko | 2017 | World Journal of Gastrointestinal Surgery2017，9，12： | 2 |
| 17 | Induction of Root Hair Growth in a Phosphorus-Buffered Culture Solution显示文摘A system to control the release of phosphate in water was successfully established, based on solubility product of [Ca2+]and [PO43-] using tricalcium phosphate as P source in the hydroponic solution, and adding CaCl2 for supplementing extraCa2+. The system, similar to soil solutions, was a P nutrient buffer solution with very low bioavailable P. The buffersolution induced the roots of both monocotyledon and dicotyledon species to grow abundant root hairs, 3 mm inmaximum length. The monocotyledons were corn (Zea mays L.) (var. Yellow Rose), wheat (Triticum aestivum L.) (var.Yanzhong 144), Triticale secale L. (var. Jingsong 5), and ryegrass (Lolium rigidum L.) (var. Ruanni), and the dicotyledonswere Arabidopsis thaliana L. (var. Columbia), white clover (Trifolium repens) (var. Kopu), Lotus (Lotus peduncucatusCav. Luliginosus Schkuhr) (var. Grasslands Maku). For these species we proved that the root environment controls theinduction of root hair formation. However, the hydroponic buffer solution failed to induce root hairs on the roots of onion(Allium cepa L.). Other investigators have concluded that corn does not form root hairs in hydroponics, but abundantlong root hairs on corn were induced by this buffer system. The roots with abundant long root hairs are called “hedgehogroots” because they have hairs everywhere just like a hedgehog. | LIU Guo-dong James Dunlop Thai Phung | 2006 | Agricultural Sciences in China2006，5，5： | 2 |
| 18 | Prediction of Flash Flood Susceptibility of Hilly Terrain Using Deep Neural Network:A Case Study of Vietnam显示文摘Flash floods are one of the most dangerous natural disasters,especially in hilly terrain,causing loss of life,property,and infrastructures and sudden disruption of traffic.These types of floods are mostly associated with landslides and erosion of roads within a short time.Most of Vietnamis hilly and mountainous;thus,the problem due to flash flood is severe and requires systematic studies to correctly identify flood susceptible areas for proper landuse planning and traffic management.In this study,three Machine Learning(ML)methods namely Deep Learning Neural Network(DL),Correlation-based FeatureWeighted Naive Bayes(CFWNB),and Adaboost(AB-CFWNB)were used for the development of flash flood susceptibility maps for hilly road section(115 km length)of National Highway(NH)-6 inHoa Binh province,Vietnam.In the proposedmodels,88 past flash flood events were used together with 14 flash floods affecting topographical and geo-environmental factors.The performance of themodels was evaluated using standard statisticalmeasures including Receiver Operating Characteristic(ROC)Curve,Area Under Curve(AUC)and Root Mean Square Error(RMSE).The results revealed that all the models performed well(AUC>0.80)in predicting flash flood susceptibility zones,but the performance of the DL model is the best(AUC:0.972,RMSE:0.352).Therefore,the DL model can be applied to develop an accurate flash flood susceptibility map of hilly terrain which can be used for proper planning and designing of the highways and other infrastructure facilities besides landuse management of the area. | Huong Thi Thanh Ngo Nguyen Duc Dam Quynh-Anh Thi Bui Nadhir Al-Ansari Romulus Costache Hang Ha Quynh Duy Bui Sy Hung Mai Indra Prakash Binh Thai Pham | 2023 | Computer Modeling in Engineering & Sciences2023，，6： | 2 |
| 19 | Osteoblastic glucocorticoid signaling exacerbates high-fat-diet-induced bone loss and obesity显示文摘Chronic high-fat diet(HFD)consumption not only promotes obesity and insulin resistance,but also causes bone loss through mechanisms that are not well understood.Here,we fed wild-type CD-1 mice either chow or a HFD(43%of energy from fat)for 18 weeks;HFD-fed mice exhibited decreased trabecular volume(-28%)and cortical thickness(-14%)compared to chow-fed mice.In HFD-fed mice,bone loss was due to reduced bone formation and mineral apposition,without obvious effects on bone resorption.HFD feeding also increased skeletal expression of sclerostin and caused deterioration of the osteocyte lacunocanalicular network(LCN).In mice fed HFD,skeletal glucocorticoid signaling was activated relative to chow-fed mice,independent of serum corticosterone concentrations.We therefore examined whether skeletal glucocorticoid signaling was necessary for HFD-induced bone loss,using transgenic mice lacking glucocorticoid signaling in osteoblasts and osteocytes(HSD2^(OB/OCY)-tg mice).In HSD2^(OB/OCY)-tg mice,bone formation and mineral apposition rates were not suppressed by HFD,and bone loss was significantly attenuated.Interestingly,in HSD2^(OB/OCY)-tg mice fed HFD,both Wnt signaling(less sclerostin induction,increased P | Sarah Kim Holger Henneicke Lauryn L.Cavanagh Eugenie Macfarlane Lee Joanne Thai Daphne Foong Sylvia J.Gasparini Colette Fong-Yee Michael M.Swarbrick Markus J.Seibel Hong Zhou | 2021 | Bone Research2021，9，4： | 2 |
| 20 | Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein显示文摘 | Li-Fan Lu To-Ha Thai Dinis Pedro Calado Ashutosh Chaudhry Masato Kubo Kentaro Tanaka Gabriel B. Loeb Hana Lee Akihiko Yoshimura Klaus Rajewsky Alexander Y. Rudensky | 2009 | Immunity2009，，1： | 2 |
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