|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice显示文摘 | Zhidan Luo Liqun Ma Zhigang Zhao Hongbo He Dachun Yang Xiaoli Feng Shuangtao Ma Xiaoping Chen Tianqi Zhu Tingbing Cao Daoyan Liu Bernd Nilius Yu Huang Zhencheng Yan Zhiming Zhu | 2012 | Cell Research2012，22，3： | 18 |
| 2 | Effects of subchronic oral toxic metal exposure on the intestinal microbiota of mice显示文摘Oral exposure to toxic metals such as cadmium(Cd), lead(Pb), copper(Cu) and aluminum(Al) can induce various adverse health effects in humans and animals. However, the effects of these metals on the gut microbiota have received limited attention. The present study demonstrated that long-term toxic metal exposure altered the intestinal microbiota of mice in a metal-specific and time-dependent manner.Subchronic oral Cu exposure for eight weeks caused a profound decline in gut microbial diversity in mice,whereas no significant changes were observed in groups treated with other metals. Cd exposure significantly increased the relative abundances of organisms from the genera Alistipes and Odoribacter and caused marked decreases in Mollicutes and unclassified Ruminococcaceae. Pb exposure significantly decreased the abundances of eight genera: unclassified and uncultured Ruminococcaceae, unclassified Lachnospiraceae, Ruminiclostridium_9, Rikenellaceae_RC9_gut_group, Oscillibacter, Anaerotruncus and Lachnoclostridium. Cu exposure affected abundances of the genera Alistipes, Bacteroides,Ruminococcaceae_UCG-014, Allobaculum, Mollicutes_RF9_norank, Rikenellaceae_RC9_gut_group,Ruminococcaceae_unclassified and Turicibacter. Al exposure increased the abundance of Odoribacter and decreased that of Anaerotruncus. Exposure to any metal for eight weeks significantly decreased the abundance of Akkermansia. These results provide a new understanding regarding the role of toxic metals in the pathogenesis of intestinal and systemic disorders in the host within the gut microbiota framework. | Qixiao Zhai Tianqi Li Leilei Yu Yue Xiao Saisai Feng Jiangping Wu Jianxin Zhao Hao Zhang Wei Chen | 2017 | Science Bulletin2017，62，12： | 12 |
| 3 | Mass-transport Deposits of the Upper Cretaceous Qingshankou Formation, Songliao Terrestrial Basin, Northeast China: Depositional Characteristics, Recognition Criteria and External Geometry显示文摘Extensive mass transport deposits(MTDs), which form a significant component of the stratigraphic record in ancient and modern deep water systems, mostly distributed in the continental margin of ocean basins worldwide. To date, no large-scale MTDs have been found in Chinese terrestrial basins. Based on integrated analysis of the seismic, drilling, core and logging data, this article report MTDs have been found in Songliao terrestrial basin(SLTB), Northeast China. During the depositional period of the Upper Cretaceous Qingshankou Formation, slope break of lacustrine basins was an ideal discharge place for gravity depositions. Regional sedimentary study of MTDs reveals that Cretaceous-age MTDs in SLTB were deposited in slope-break environments by slide, slump and debris flow, and MTDs were mixed with little turbidite simultaneously. Besides the massive aspect, key features of MTDs are the common presence of deformational structures or softsedimentary deformation, floating shale clasts, boudins, microfaults, distortion beddings, rotated sand debris. Detailed mapping of two three-dimensional(3-D) seismic surveys acquired in Yingtai(YT) and Haituozi(HTZ) areas reveals that MTDs are characterized by chaotic, mounded, and transparent seismic reflection. Growth fault, slope gully and geomorphology of the slope break greatly influenced the sedimentary process and external geometry of MTDs, and as a consequence, MTDs in SLTB exhibit classic fan-like geometry and some special(non-fan-like) external geometry. Furthermore, fanlike MTDs can be divided into three subcategories, including isolated fan, mother-son fan and stacked fan. Non-fan-like MTDs can be divided into two subcategories, strip-like MTDs and faulted-pit MTDs. A new sedimentary model has been built for MTDs in SLTB. MTDs have become a new exploration and development target in the SLTB. | PAN Shuxin WEI Pingsheng WANG Tianqi LIU Caiyan CHEN Bintao LIANG Sujuan | 2014 | Acta Geologica Sinica(English Edition)2014，88，1： | 9 |
| 4 | Release of VEGF and BMP9 from injectable alginate based composite hydrogel for treatment of myocardial infarction显示文摘Myocardial infarction(MI)is one of cardiovascular diseases that pose a serious threat to human health.The pathophysiology of MI is complex and contains several sequential phases including blockage of a coronary artery,necrosis of myocardial cells,inflammation,and myocardial fibrosis.Aiming at the treatment of different stages of MI,in this work,an injectable alginate based composite hydrogel is developed to load vascular endothelial active factor(VEGF)and silk fibroin(SF)microspheres containing bone morphogenetic protein 9(BMP9)for releasing VEGF and BMP9 to realize their respective functions.The results of in vitro experiments indicate a rapid initial release of VEGF during the first few days and a relatively slow and sustained release of BMP9 for days,facilitating the formation of blood vessels in the early stage and inhibiting myocardial fibrosis in the long-term stage,respectively.Intramyocardial injection of such composite hydrogel into the infarct border zone of mice MI model via multiple points promotes angiogenesis and reduces the infarction size.Taken together,these results indicate that the dual-release of VEGF and BMP9 from the composite hydrogel results in a collaborative effect on the treatment of MI and improvement of heart function,showing a promising potential for cardiac clinical application. | Yong Wu Tianqi Chang Weiqian Chen Xiaoyu Wang Jingjing Li Yueqiu Chen You Yu Zhenya Shen Qian Yu Yanxia Zhang | 2021 | Bioactive Materials2021，6，2： | 7 |
| 5 | N‑Doped Graphene‑Decorated NiCo Alloy Coupled with Mesoporous NiCoMoO Nano‑sheet Heterojunction for Enhanced Water Electrolysis Activity at High Current Density显示文摘Developing highly effective and stable non-noble metalbased bifunctional catalyst working at high current density is an urgent issue for water electrolysis(WE).Herein,we prepare the N-doped graphene-decorated NiCo alloy coupled with mesoporous NiCoMoO nano-sheet grown on 3D nickel foam(NiCo@C-NiCoMoO/NF)for water splitting.NiCo@C-NiCoMoO/NF exhibits outstanding activity with low overpotentials for hydrogen and oxygen evolution reaction(HER:39/266 mV;OER:260/390 mV)at±10 and±1000 mA cm^(−2).More importantly,in 6.0 M KOH solution at 60℃ for WE,it only requires 1.90 V to reach 1000 mA cm−2 and shows excellent stability for 43 h,exhibiting the potential for actual application.The good performance can be assigned to N-doped graphene-decorated NiCo alloy and mesoporous NiCoMoO nano-sheet,which not only increase the intrinsic activity and expose abundant catalytic activity sites,but also enhance its chemical and mechanical stability.This work thus could provide a promising material for industrial hydrogen production. | Guangfu Qian Jinli Chen Tianqi Yu Lin Luo Shibin Yin | 2021 | Nano-Micro Letters2021，13，5： | 7 |
| 6 | NON-YELLOWING2 (NYE2), a Close Paralog of NYE1, Plays a Positive Role in Chlorophyll Degradation in Arabidopsis显示文摘 | Wu, Shouxin Li, Zhongpeng Yang, Lifeng Xie, Zuokun Chen, Junyi Zhang, Wei Liu, Tianqi Gao, Shan Gao, Jiong Zhu, Yihua Xin, Jiwen Ren, Guodong Kuai, Benke | 2016 | Molecular Plant2016，9，4： | 6 |
| 7 | A Survey of Accelerator Architectures for Deep Neural Networks显示文摘Recently,due to the availability of big data and the rapid growth of computing power,artificial intelligence(AI)has regained tremendous attention and investment.Machine learning(ML)approaches have been successfully applied to solve many problems in academia and in industry.Although the explosion of big data applications is driving the development of ML,it also imposes severe challenges of data processing speed and scalability on conventional computer systems.Computing platforms that are dedicatedly designed for AI applications have been considered,ranging from a complement to von Neumann platforms to a“must-have”and stand-alone technical solution.These platforms,which belong to a larger category named“domain-specific computing,”focus on specific customization for AI.In this article,we focus on summarizing the recent advances in accelerator designs for deep neural networks(DNNs)-that is,DNN accelerators.We discuss various architectures that support DNN executions in terms of computing units,dataflow optimization,targeted network topologies,architectures on emerging technologies,and accelerators for emerging applications.We also provide our visions on the future trend of AI chip designs. | Yiran Chen Yuan Xie Linghao Song Fan Chen Tianqi Tang | 2020 | Engineering2020，6，3： | 5 |
| 8 | Joint multiple parameters estimation for coherent chirp signals using vector sensor array显示文摘In this paper, an algorithm is proposed to estimate starting frequency (SF), chirp rate (CR), 2-D direction-of-arrivals (DOA) and polarization of coherent chirp signals with vector sensor arrays. The fractional Fourier transformation (FRFT) is used to estimate SF and CR of chirp signals in this method. And a new correlation matrix is reconstructed to suppress the noise. The property of the vector sensor array is employed to solve the problem of insufficient rank from signal coherence. The L-shaped uniform array of expend aperture is used to improve the precision of estimation, and the method of solving the ambiguity of angle under the condition of coherent signals is presented. The performance of this algorithm is compared with that of spatial smoothing method to verify the efficacy of this approach. | WEN Zhong LI LiPing CHEN TianQi ZHANG XiXiang | 2008 | Science in China(Series F)2008，51，1： | 4 |
| 9 | Three-Phase Heterojunction NiMo-Based Nano-Needle for Water Splitting at Industrial Alkaline Condition显示文摘Constructing heterojunction is an effective strategy to develop high-performance non-preciousmetal-based catalysts for electrochemical water splitting(WS).Herein,we design and prepare an N-doped-carbon-encapsulated Ni/MoO_(2) nano-needle with three-phase heterojunction(Ni/MoO_(2)@CN)for accelerating the WS under industrial alkaline condition.Density functional theory calculations reveal that the electrons are redistributed at the three-phase heterojunction interface,which optimizes the adsorption energy of H-and O-containing intermediates to obtain the best ΔG_(H*) for hydrogen evolution reaction(HER)and decrease the ΔG value of ratedetermining step for oxygen evolution reaction(OER),thus enhancing the HER/OER catalytic activity.Electrochemical results confirm that Ni/MoO_(2)@CN exhibits good activity for HER(ƞ_(-10)=33 mV,ƞ_(-1000)=267 mV)and OER(ƞ_(10)=250 mV,ƞ_(1000)=420 mV).It shows a low potential of 1.86 V at 1000 mA cm^(−2) for WS in 6.0 M KOH solution at 60℃ and can steadily operate for 330 h.This good HER/OER performance can be attributed to the three-phase heterojunction with high intrinsic activity and the self-supporting nano-needle with more active sites,faster mass diffusion,and bubbles release.This work provides a unique idea for designing high efficiency catalytic materials for WS. | Guangfu Qian Jinli Chen Tianqi Yu Jiacheng Liu Lin Luo Shibin Yin | 2022 | Nano-Micro Letters2022，14，1： | 4 |
| 10 | Traditional Chinese Medicines alleviated myocardial ischemia by regulating Qi and promoting blood circulation显示文摘OBJECTIVE:To investigate the efficacy of Chinese medicines on Qi stagnation and blood stasis in rats with myocardial ischemia.METHODS:Fifty male Wistar rats were randomly divided into five groups(n=10)as follows:(a)sham operation(Sham),(b)myocardial ischemia(Model),(c)treatment that regulates Qi(Qi),(d)treatment that promotes blood circulation(Blood),(e)treatment that both regulates Qi and promotes blood circulation(QB).The rat model was established via activities restriction for 6 h followed by tail clamp stimulation for 5 mins every day for 7 d and occlusion left coronary anterior descending artery.Afterwards rats were treated with medicines that regulate Qi and/or promote blood circulation via gavage for 14 d.Behavioral parameters were evaluated using open field and elevated plus-maze tests.The tongue color and sublingual vein were visually examined.Blood flow perfusion of tongue and auricle were detected using PIMⅡ.The mesenteric microcirculation was examined via capillaroscopy,and hemodynamics was assessed using a polygraph system.Serum homocysteine(Hcy),creatine kinase isoenzyme(CKMB)levels and endothelin-1(ET-1)were measured.Hematoxylin and eosin staining and transmission electron microscopy were employed to detect the myocardial morphology and ultrastructure,respectively.RESULTS:Compared with findings in Sham group,rats in model group had coarse hair,dark mucosa of the lips and claw,low activity,and increased anxiety.Compared with findings in Model group,rats in the three treatment groups exhibited a lighter tongue color without an extended and varicose sublingual vein.There were significant increases of auricle blood flow perfusion in the Qi group and tongue bottom blood flow perfusion in the QB group.Compared with findings in Model rats,rats in Blood group exhibited improved mesenteric microcirculation associated with increased mesenteric blood flow and a larger arteriole diameter.Moreover,compared with findings in Model rats,Qi and QB rats exhibited increased left ventricular±dp/dtmax,decreased serum CKMB,Hcy,ET-1 levels,and reduced myocardial ultrastructural damage.CONCLUSION:Myocardial ischemia damage was suppressed by Traditional Chinese Medicines that regulate Qi and promote blood circulation. | Wang Chen Wang Xiaoreng Tao Tianqi Song Dandan Wang Jianli Wang You Liu Xiuhua Wu Xudong | 2020 | Journal of Traditional Chinese Medicine2020，40，6： | 4 |
| 11 | New direction of arrival estimation method for wideband coherent signals显示文摘To estimate the direction-of-arrival (DOA) of wideband coherent signals, a new method by modifying the orthogonality of the projected subspaces method is proposed. And it can deal with randomly position perturbed arrays by using the Toeplitz method. This method needn't the primary information of DOA for focusing matrix and the sector dividing of interpolated method, which improving the precision of estimation and reducing the computational complexity. Simulations illustrate the effectiveness of this method. | Wang Ling Yin Jihao Chen Tianqi | 2008 | Journal of Systems Engineering and Electronics2008，19，3： | 4 |
| 12 | Extremely regular periodic surface structures in a large area efficiently induced on silicon by temporally shaped femtosecond laser显示文摘Femtosecond laser-induced periodic surface structures(LIPSS) have several applications in surface structuring and functionalization. Three major challenges exist in the fabrication of regular and uniform LIPSS: enhancing the periodic energy deposition, reducing the residual heat, and avoiding the deposited debris. Herein, we fabricate an extremely regular low-spatial-frequency LIPSS(LSFL) on a silicon surface by a temporally shaped femtosecond laser. Based on a 4 f configuration zero-dispersion pulse shaping system, a Fourier transform limit(FTL) pulse is shaped into a pulse train with varying intervals in the range of 0.25–16.2 ps using periodic π-phase step modulation. Under the irradiation of the shaped pulse with an interval of 16.2 ps, extremely regular LSFLs are efficiently fabricated on silicon. The scan velocity for fabricating regular LSFL is 2.3 times faster, while the LSFL depth is 2 times deeper, and the diffraction efficiency is 3 times higher than those of LSFL using the FTL pulse.The formation mechanisms of regular LSFL have been studied experimentally and theoretically. The results show that the temporally shaped pulse enhances the excitation of surface plasmon polaritons and the periodic energy deposition while reducing the residual thermal effects and avoiding the deposition of the ejected debris, eventually resulting in regular and deeper LSFL on the silicon surface. | YUCHAN ZHANG QILIN JIANG KAIQIANG CAO TIANQI CHEN KE CHENG SHIAN ZHANG DONGHAI FENG TIANQING JIA ZHENRONG SUN JIANRONG QIU | 2021 | Photonics Research2021，9，5： | 4 |
| 13 | A Smooth and Efficient Gait Planning for Humanoids Based on Human ZMP显示文摘Based on the ZMP(zero moment point)trajectory and the walking data of human,a new method is proposed to improve the robot walking smoothness as well as to save energy.Firstly,a measurement system is designed to measure the data of humans including the ZMP trajectory and the waist trajectory.Secondly,a new gait planning method which includes presetting the allowable ZMP region is proposed through analyzing human data.Thirdly,the new planning method is applied to the multi-link model based gait planning method.Finally,the feasibility of the proposed method is verified by simulation and experiments. | YANG Tianqi ZHANG Weimin HUANG Qiang CHEN Xuechao YU Zhanguo MENG Libo | 2017 | 机器人2017，39，5： | 3 |
| 14 | SDNMS: A Software Defined Network Measurement System for NFV Networks显示文摘As a promising technology to completely transform how we architect, deploy, operate and manage various networks, software-based Network Function Virtualization(NFV) enables hardware-independent, flexible, fast and efficient network service provision. With the increasing popularity of NFV paradigm, the Internet has also transformed to be a hybrid environment where NFV-based network entities coexist with traditional network devices. To facilitate our understanding, design, evaluate and manage of such novel network environment, there is a great need for a new NFV-compatible network measurement system which is still in absent so far. To bridge this gap, a system, named Software Defined Network Measurement System(SDNMS), is presented in this paper. Firstly, the architecture of SDNMS is proposed. In this architecture, a formal method to describe the working mode of the network measurement is defined. This method can also be utilized to generate a network measurement middle box(NMMB) in a specific location of the NFV network according to the customized description file, and to flexibly deploy the network measurement function. Secondly, the technology of virtual network measurement function(VNMF) combined with LXC is studied to form NMMB function. Thirdly, a control method is presented to control the start, stop, and update NMMB to form a specific network measurement system function. Finally, a prototype of SDNMS with network monitoring function to monitor network performance anomalies and locate faults is introduced. Experimental results have shown that SDNMS architecture and related technologies are feasible and effective to deploy and control network measurement functions in NFV networks. We hope SDNMS could provide a new method for practitioners to conduct network management and research at the age of NFV. | Tianqi Zhang Ming Chen Xianglin Wei Bing Chen Chao Hu | 2019 | China Communications2019，16，4： | 3 |
| 15 | Cancer classification with data augmentation based on generative adversarial networks显示文摘Accurate diagnosis is a significant step in cancer treatment.Machine learning can support doctors in prognosis decision-making,and its performance is always weakened by the high dimension and small quantity of genetic data.Fortunately,deep learning can effectively process the high dimensional data with growing.However,the problem of inadequate data remains unsolved and has lowered the performance of deep learning.To end it,we propose a generative adversarial model that uses non target cancer data to help target generator training.We use the reconstruction loss to further stabilize model training and improve the quality of generated samples.We also present a cancer classification model to optimize classification performance.Experimental results prove that mean absolute error of cancer gene made by our model is 19.3%lower than DC-GAN,and the classification accuracy rate of our produced data is higher than the data created by GAN.As for the classification model,the classification accuracy of our model reaches 92.6%,which is 7.6%higher than the model without any generated data. | Kaimin WEI Tianqi LI Feiran HUANG Jinpeng CHEN Zefan HE | 2022 | Frontiers of Computer Science2022，16，2： | 2 |
| 16 | A time-driven transmission method for well logging networks显示文摘Long delays and poor real-time transmission are disadvantageous to well logging networks consisting of multiple subnets.In this paper,we proposed a time-driven transmission method(TDTM)to improve the efficiency and precision of logging networks.Using TDTM,we obtained well logging curves by fusing the depth acquired on the surface,and the data acquired in downhole instruments based on the synchronization timestamp.For the TDTM,the precision of time synchronization and the data fusion algorithm were two main factors influencing system errors.A piecewise fractal interpolation was proposed to fast fuse data in each interval of the logging curves.Intervals with similar characteristics in curves were extracted based on the change in the histogram of the interval.The TDTM is evaluated with a sonic curve,as an example.Experimental results showed that the fused data had little error,and the TDTM was effective and suitable for the logging networks. | Wu Ruiqing Chen Wei Chen Tianqi Li Qun | 2009 | Petroleum Science2009，6，3： | 2 |
| 17 | DFT based channel estimation methods for OFDM 显示文摘 | ZHANG Wei CHEN Qianbin ZHANG Tianqi | 2007 | Journal of Chongqing University of Posts and Telecommuni- cations : Natural Science Edition2007，19，4： | 1 |
| 18 | Comparative Study on Coastal Depth Inversion Based on Multi-source Remote Sensing Data显示文摘Coastal depth is an important research focus of coastal waters and is also a key factor in coastal environment. Dongluo Island in South China Sea was taken as a typical study area. The band ratio model was established by using measured points and three multispectral images of Landsat-8, SPOT-6(Systeme Probatoire d'Observation de la Terre, No.6) and WorldView-2. The band ratio model with the highest accuracy is selected for the depth inversion respectively. The results show that the accuracy of SPOT-6 image is the highest in the inversion of coastal depth. Meanwhile, analyzing the error of inversion from different depth ranges, the accuracy of the inversion is lower in the range of 0–5 m because of the influence of human activities. The inversion accuracy of 5–10 m is the highest, and the inversion error increases with the increase of water depth in the range of 5–20 m for the three kinds of satellite images. There is no linear relationship between the accuracy of remote sensing water depth inversion and spatial resolution of remote sensing data, and it is affected by performance and parameters of sensor. It is necessary to strengthen the research of remote sensor in order to further improve the accuracy of inversion. | LU Tianqi CHEN Shengbo TU Yuan YU Yan CAO Yijing JIANG Deyang | 2019 | Chinese Geographical Science2019，29，2： | 1 |
| 19 | Ammonia promotes the proliferation of bone marrow-derived mesenchymal stem cells by regulating the Akt/mTOR/S6k pathway显示文摘Ammonia plays an important role in cellular metabolism.However,ammonia is considered a toxic product.In bone marrow-derived mesenchymal stem cells,multipotent stem cells with high expression of glutamine synthetase(GS)in bone marrow,ammonia and glutamate can be converted to glutamine via glutamine synthetase activity to support the proliferation of MSCs.As a major nutritional amino acid for biosynthesis,glutamine can activate the Akt/mTOR/S6k pathway to stimulate cell proliferation.The activation of mTOR can promote cell entry into S phase,thereby enhancing DNA synthesis and cell proliferation.Our studies demonstrated that mesenchymal stem cells can convert the toxic waste product ammonia into nutritional glutamine via GS activity.Then,the Akt/mTOR/S6k pathway is activated to promote bone marrow-derived mesenchymal stem cell proliferation.These results suggest a new therapeutic strategy and potential target for the treatment of diseases involving hyperammonemia. | Yu Liu Xiangxian Zhang Wei Wang Ting Liu Jun Ren Siyuan Chen Tianqi Lu Yan Tie Xia Yuan Fei Mo Jingyun Yang Yuquan Wei Xiawei Wei | 2022 | Bone Research2022，10，4： | 1 |
| 20 | Direction-of-arrival estimation using a sparse representation of array covariance vectors 显示文摘 | Yin Jihao Chen Tianqi | 2011 | IEEE Transactions on Signal Processing2011，59，9： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员