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| 1 | Gully Erosion Regionalization of Black Soil Area in Northeastern China显示文摘Gully erosion is the frequent and main form of soil erosion in the black soil area of the northeastern China, which is one of the most important commodity grain production bases in China. It is encroaching upon the fertile farmland there. Regionalization of gully erosion can reveal the spatial distribution and regularity of the development of gully erosion. Based on the eco-geographical regional background features of the black soil area, this study combined the regionalization with influencing factors of the development of gully erosion. GIS spatial analysis, geostatistical analysis, spatial statistics, reclassification, debris polygon processing and map algebra methods were employed. As a result, the black soil area was divided into 12 subregions. The field survey data on type, length, volume and other characteristics indicators of gully erosion were used to calibrate the results. Then the features of every subregion, such as where the gully erosion is, how serious it is, and why it happens and develops, were expounded. The result is not only an essential prerequisite for gully erosion surveys and monitoring, but also an important basis for gully erosion prevention. | YANG Jiuchun ZHANG Shuwen CHANG Liping LI Fei LI Tianqi GAO Yan | 2017 | Chinese Geographical Science2017,27,1: | 13 |
| 2 | Effects of subchronic oral toxic metal exposure on the intestinal microbiota of mice显示文摘Oral exposure to toxic metals such as cadmium(Cd), lead(Pb), copper(Cu) and aluminum(Al) can induce various adverse health effects in humans and animals. However, the effects of these metals on the gut microbiota have received limited attention. The present study demonstrated that long-term toxic metal exposure altered the intestinal microbiota of mice in a metal-specific and time-dependent manner.Subchronic oral Cu exposure for eight weeks caused a profound decline in gut microbial diversity in mice,whereas no significant changes were observed in groups treated with other metals. Cd exposure significantly increased the relative abundances of organisms from the genera Alistipes and Odoribacter and caused marked decreases in Mollicutes and unclassified Ruminococcaceae. Pb exposure significantly decreased the abundances of eight genera: unclassified and uncultured Ruminococcaceae, unclassified Lachnospiraceae, Ruminiclostridium_9, Rikenellaceae_RC9_gut_group, Oscillibacter, Anaerotruncus and Lachnoclostridium. Cu exposure affected abundances of the genera Alistipes, Bacteroides,Ruminococcaceae_UCG-014, Allobaculum, Mollicutes_RF9_norank, Rikenellaceae_RC9_gut_group,Ruminococcaceae_unclassified and Turicibacter. Al exposure increased the abundance of Odoribacter and decreased that of Anaerotruncus. Exposure to any metal for eight weeks significantly decreased the abundance of Akkermansia. These results provide a new understanding regarding the role of toxic metals in the pathogenesis of intestinal and systemic disorders in the host within the gut microbiota framework. | Qixiao Zhai Tianqi Li Leilei Yu Yue Xiao Saisai Feng Jiangping Wu Jianxin Zhao Hao Zhang Wei Chen | 2017 | Science Bulletin2017,62,12: | 12 |
| 3 | Remote Sensing Monitoring of Gullies on a Regional Scale: A Case Study of Kebai Region in Heilongjiang Province, China显示文摘Gully erosion is one of the major causes of land degradation in most areas and attracts increasing attention from researchers. We monitored gullies in the Kebai region in Heilongjiang Province of China by using remote sensing data and found that gully density increased with the increase in slope when the slope was less than 3°. Gully density in sunny slopes or windward slopes was greater than in shady slopes or leeward slopes because of the impacts of freezing and thawing, wind and solar radiation. Specifically, the gully density in northeast slope was the greatest and in southwest was the smallest. Gully density was reduced with increasing slope length and the longer the slope length, the less the gully density changed between 1965 and 2005. Affected by runoff, gullies most easily to occur in concave slopes and the critical elevation for gully erosion was 250–275 m. Moreover, hilly regions had the greatest gully density, followed by tableland regions, whereas the gully density in flatlands was the lowest. However, the gully density of these three types of landforms all increased between 1945 and 2000, and the portion of increase was 57.45%(hill), 52.91%(mesa) and 25.32%(plain), respectively. | ZHANG Shuwen LI Fei LI Tianqi YANG Jiuchun BU Kun CHANG Liping WANG Wenjuan YAN Yechao | 2015 | Chinese Geographical Science2015,25,5: | 10 |
| 4 | Release of VEGF and BMP9 from injectable alginate based composite hydrogel for treatment of myocardial infarction显示文摘Myocardial infarction(MI)is one of cardiovascular diseases that pose a serious threat to human health.The pathophysiology of MI is complex and contains several sequential phases including blockage of a coronary artery,necrosis of myocardial cells,inflammation,and myocardial fibrosis.Aiming at the treatment of different stages of MI,in this work,an injectable alginate based composite hydrogel is developed to load vascular endothelial active factor(VEGF)and silk fibroin(SF)microspheres containing bone morphogenetic protein 9(BMP9)for releasing VEGF and BMP9 to realize their respective functions.The results of in vitro experiments indicate a rapid initial release of VEGF during the first few days and a relatively slow and sustained release of BMP9 for days,facilitating the formation of blood vessels in the early stage and inhibiting myocardial fibrosis in the long-term stage,respectively.Intramyocardial injection of such composite hydrogel into the infarct border zone of mice MI model via multiple points promotes angiogenesis and reduces the infarction size.Taken together,these results indicate that the dual-release of VEGF and BMP9 from the composite hydrogel results in a collaborative effect on the treatment of MI and improvement of heart function,showing a promising potential for cardiac clinical application. | Yong Wu Tianqi Chang Weiqian Chen Xiaoyu Wang Jingjing Li Yueqiu Chen You Yu Zhenya Shen Qian Yu Yanxia Zhang | 2021 | Bioactive Materials2021,6,2: | 7 |
| 5 | NON-YELLOWING2 (NYE2), a Close Paralog of NYE1, Plays a Positive Role in Chlorophyll Degradation in Arabidopsis显示文摘 | Wu, Shouxin Li, Zhongpeng Yang, Lifeng Xie, Zuokun Chen, Junyi Zhang, Wei Liu, Tianqi Gao, Shan Gao, Jiong Zhu, Yihua Xin, Jiwen Ren, Guodong Kuai, Benke | 2016 | Molecular Plant2016,9,4: | 6 |
| 6 | Performance of the Autism Spectrum Rating Scale and Social Responsiveness Scale in Identifying Autism Spectrum Disorder Among Cases of Intellectual Disability显示文摘The Autism Spectrum Rating Scale(ASRS) and the Social Responsiveness Scale(SRS) have been widely used for screening autism spectrum disorder(ASD) in the general population during epidemiological studies, but studies of individuals with intellectual disability(ID) are quite limited. Therefore, we recruited the parents/caregivers of 204 ASD cases, 71 ID cases aged 6–18 years from special education schools, and 402 typically developing(TD) children in the same age span from a communitybased population to complete the ASRS and SRS. The results showed that the ID group scored significantly lower on total and subscale scores than the ASD group on both scales(P \ 0.05) but higher than TD children(P \ 0.05).Receiver operating characteristic analyses demonstrated a similar fair performance in discriminating ASD from ID with the ASRS(area under the curve(AUC) = 0.709,sensitivity = 77.0%, specificity = 52.1%, positive predictive value(PPV) = 82.2%) and the SRS(AUC = 0.742,sensitivity = 59.8%, specificity = 77.5%, PPV = 88.4%).The results showed that individuals with ID had clear autistic traits and discriminating ASD from ID cases was quite challenging, while assessment tools such as ASRS and SRS, help to some degree. | Chunpei Li Hao Zhou Tianqi Wang Shasha Long Xiaonan Du Xiu Xu Weili Yan Yi Wang | 2018 | Neuroscience Bulletin2018,34,6: | 5 |
| 7 | Small molecules in targeted cancer therapy:advances,challenges,and future perspectives显示文摘Due to the advantages in efficacy and safety compared with traditional chemotherapy drugs,targeted therapeutic drugs have become mainstream cancer treatments.Since the first tyrosine kinase inhibitor imatinib was approved to enter the market by the US Food and Drug Administration(FDA)in 2001,an increasing number of small-molecule targeted drugs have been developed for the treatment of malignancies.By December 2020,89 small-molecule targeted antitumor drugs have been approved by the US FDA and the National Medical Products Administration(NMPA)of China.Despite great progress,small-molecule targeted anti-cancer drugs still face many challenges,such as a low response rate and drug resistance.To better promote the development of targeted anti-cancer drugs,we conducted a comprehensive review of small-molecule targeted anti-cancer drugs according to the target classification.We present all the approved drugs as well as important drug candidates in clinical trials for each target,discuss the current challenges,and provide insights and perspectives for the research and development of anti-cancer drugs. | Lei Zhong Yueshan Li Liang Xiong Wenjing Wang Ming Wu Ting Yuan Wei Yang Chenyu Tian Zhuang Miao Tianqi Wang Shengyong Yang | 2021 | Signal Transduction and Targeted Therapy2021,6,6: | 5 |
| 8 | Joint multiple parameters estimation for coherent chirp signals using vector sensor array显示文摘In this paper, an algorithm is proposed to estimate starting frequency (SF), chirp rate (CR), 2-D direction-of-arrivals (DOA) and polarization of coherent chirp signals with vector sensor arrays. The fractional Fourier transformation (FRFT) is used to estimate SF and CR of chirp signals in this method. And a new correlation matrix is reconstructed to suppress the noise. The property of the vector sensor array is employed to solve the problem of insufficient rank from signal coherence. The L-shaped uniform array of expend aperture is used to improve the precision of estimation, and the method of solving the ambiguity of angle under the condition of coherent signals is presented. The performance of this algorithm is compared with that of spatial smoothing method to verify the efficacy of this approach. | WEN Zhong LI LiPing CHEN TianQi ZHANG XiXiang | 2008 | Science in China(Series F)2008,51,1: | 4 |
| 9 | A novel evolving model for power grids显示文摘In this paper,a novel power grid evolving model,which can well describe the evolving property of power grids,is presented. Based on the BA model,motivated by the fact that in real power grids,connectivity of node not only depends on its degree,but also is influenced by many uncertain factors,so we introduce the subconnection factor K for each node. Using the mean-field theory,we get the analytical expression of power-law degree distribution with the exponent γ∈ (3,∞ ). Finally,simulation results show that the new model can provide a satisfactory description for empirical characteristics of power network,and power network falls somewhere in between scale-free network and uncertain network. | LIU Xuan, LIU TianQi & LI XingYuan School of Electrical Engineering and Automation, Sichuan University, Chengdu 610065, China | 2010 | Science China(Technological Sciences)2010,53,10: | 4 |
| 10 | Abscisic acid signaling negatively regulates nitrate uptake via phosphorylation of NRT1.1 by SnRK2s in Arabidopsis显示文摘Nitrogen(N)is a limiting nutrient for plant growth and productivity.The phytohormone abscisic acid(ABA)has been suggested to play a vital role in nitrate uptake in fluctuating N environments.However,the molecular mechanisms underlying the involvement of ABA in N deficiency responses are largely unknown.In this study,we demonstrated that ABA signaling components,particularly the three subclass Ⅲ SUCROSE NON-FERMENTING1(SNF1)-RELATED PROTEIN KINASE 2 S(SnRK2)proteins,function in root foraging and uptake of nitrate under N deficiency in Arabidopsis thaliana.The snrk2.2 snrk2.3 snrk2.6 triple mutant grew a longer primary root and had a higher rate of nitrate influx and accumulation compared with wild-type plants under nitrate deficiency.Strikingly,SnRK2.2/2.3/2.6 proteins interacted with and phosphorylated the nitrate transceptor NITRATE TRANSPORTER1.1(NRT1.1)in vitro and in vivo.The phosphorylation of NRT1.1 by SnRK2 s resulted in a significant decrease of nitrate uptake and impairment of root growth.Moreover,we identified NRT1.1Ser585 as a previously unknown functional site:the phosphomimetic NRT1.1S585 D was impaired in both low-and high-affinity transport activities.Taken together,our findings provide new insight into how plants fine-tune growth via ABA signaling under N deficiency. | Hang Su Tian Wang Chuanfeng Ju Jinping Deng Tianqi Zhang Mengjiao Li Hui Tian Cun Wang | 2021 | Journal of Integrative Plant Biology2021,63,3: | 4 |
| 11 | PEG-assisted Hydrothermal synthesis and photoluminescence of CdMoO 4 :Tb 3+ green phosphor显示文摘 | Junjun Zhang Tianqi Zhao Bingnan Wang Linlin Li Lianchun Zou Shucai Gan | 2014 | Journal of Physics and Chemistry of Solids2014,,: | 4 |
| 12 | Comparison and Analysis of Agricultural and Forest Land Changes in Typical Agricultural Regions of Northern Mid-latitudes显示文摘The northeastern China, the United States, and the western Europe are important agricultural regions both on the global and regional scales. The western Europe has a longer history of agricultural land development than the eastern United States. These two regions have changed from the deforestation and reclamation phase in the past to the current land abandonment and reforestation phase. Compared with the two regions, large-scale land exploitation has only been practiced in the northeastern China during the last century. After a short high-intensity deforestation and reclamation period, agricultural and forest lands are basically in a dynamic steady state. By comparing domestic and international agro-forestry development and considering the ecological environment and socio-economic benefits that can be derived from agro-forestry, this paper suggests that large area of reforestation would be inevitable in future though persistent and large agricultural demand in coming decades even more. And local reforestation at slope farmland with ecological vulnerability should be imperative at present to avoid severer damage. At the same time, from the perspective of Land Change Science, the results demonstrate that the research on land use change in the agro-forestry ecotone is typical and critical, particularly those dealing with the analysis of spatial and temporal characteristics and the simulation of climate, hydrology, and other environmental effects. | LIU Tingxiang ZHANG Shuwen TANG Junmei LI Tianqi | 2013 | Chinese Geographical Science2013,23,2: | 3 |
| 13 | A New Species of the Genus Achalinus from Huangshan, Anhui, China(Squamata: Xenodermidae)显示文摘A new species of the genus Achalinus is described based on five specimens collected from the villages of Huangjialing and Fuxi, Huangshan, Anhui, China. It can be morphologically differentia ted from all the other species in Achalinus except for A. spinalis and A. werneri by the presence of a dotted black streak in the middle of the subcaudal. It can be distinguished from A. spinalis in that its two anterior temporals are in contact with eye, and A. werneri by its light brown flanks. The phylogenetic rela tionship of Achalinus was reconstructed using the mitochondrial locus of cytochrome coxidase subunit 1(CO1). The five new specimens form a monophyletic clade with strong support. The uncorrected p-dista nces between the new species and other representatives of Achalinus range from 13.6% to 21.7%. The recognition of the new species increases the number of described Achalinus species to 14. | Ruyi HUANG Lifang PENG Lei YU Tianqi HUANG Ke JIANG Li DING Jinkang CHANG Diancheng YANG Yuhao XU Song HUANG | 2021 | Asian Herpetological Research2021,12,2: | 3 |
| 14 | The Arabidopsis catalase triple mutant reveals important roles of catalases and peroxisome-derived signaling in plant development显示文摘Hydrogen peroxide(H_2O_2)is generated in many metabolic processes.As a signaling molecule,H_2O_2plays important roles in plant growth and development,as well as environmental stress response.In Arabidopsis,there are three catalase genes,CAT1,CAT2,and CAT3.The encoded catalases are predominately peroxisomal proteins and are critical for scavenging H_2O_2.Since CAT1 and CAT3 are linked on chromosome 1,it has been almost impossible to generate cat1/3 and cat1/2/3 mutants by traditional genetic tools.In this study,we constructed cat1/3 double mutants and cat1/2/3 triple mutants by CRISPR/Cas9 to investigate the role of catalases.The cat1/2/3 triple mutants displayed severe redox disturbance and growth defects under physiological conditions compared with wild-type and the cat2/3 double mutants.Transcriptome analysis showed a more profound transcriptional response in the cat1/2/3 triple mutants compared to the cat2/3 mutants.These differentially expressed genes are involved in plant growth regulation as well as abiotic and biotic stress responses.In addition,expression of OXI1(OXIDATIVE SIGNAL INDUCIBLE 1)and several MAPK cascade genes were changed dramatically in the catalase triple mutant,suggesting that H_2O_2produced in peroxisomes could serve as a peroxisomal retrograde signal. | Tong Su Pingping Wang Huijuan Li Yiwu Zhao Yao Lu Peng Dai Tianqi Ren Xiaofeng Wang Xuezhi Li Qun Shao Dazhong Zhao Yanxiu Zhao Changle Ma | 2018 | Journal of Integrative Plant Biology2018,60,7: | 3 |
| 15 | Tunable seesaw-like 3D capacitive sensor for force and acceleration sensing显示文摘To address the resource-competing issue between high sensitivity and wide working range for a stand-alone sensor,development of capacitive sensors with an adjustable gap between two electrodes has been of growing interest.While several approaches have been developed to fabricate tunable capacitive sensors,it remains challenging to achieve,simultaneously,a broad range of tunable sensitivity and working range in a single device.In this work,a 3D capacitive sensor with a seesaw-like shape is designed and fabricated by the controlled compressive buckling assembly,which leverages the mechanically tunable configuration to achieve high-precision force sensing(resolution~5.22 nN)and unprecedented adjustment range(by~33 times)of sensitivity.The mechanical tests under different loading conditions demonstrate the stability and reliability of capacitive sensors.Incorporation of an asymmetric seesaw-like structure design in the capacitive sensor allows the acceleration measurement with a tunable sensitivity.These results suggest simple and low-cost routes to high-performance,tunable 3D capacitive sensors,with diverse potential applications in wearable electronics and biomedical devices. | Jilong Ye Fan Zhang Zhangming Shen Shunze Cao Tianqi Jin Xiaogang Guo Zhihong Li Li Lin Yihui Zhang | 2021 | npj Flexible Electronics2021,5,1: | 2 |
| 16 | Identifying the Optimal Age for Herpes Zoster Vaccination—Yichang City,Hubei Province,China,2017–2019显示文摘Summary What is already known about this topic?Herpes zoster(shingles)is a common skin condition in older adults,which usually presents as a painful rash with blisters.Vaccination is the most effective method to prevent shingles.However,there is not sufficient population-based epidemiological data in China to optimize the timing of zoster vaccination.What is added by this report?Clustering analyses of population-wide epidemiological data from the Healthcare Big Data Platform in Yichang,China showed that the average annual zoster incidence is the highest among people 55 years or older,at 10 cases per thousand persons per year,making this age group the optimal target population for vaccination.Incidence was lower but increased with age among younger adults,28–54 years old.What are the implications for public health practice?With limited vaccination resources,zoster vaccinations should be targeted at adults 55 years or older who are at the greatest risk for shingles.Research should be conducted to understand the risk of shingles among young and middle-aged adults and identify triggers of shingles:potentially leading to preventive measures. | Meiying You Tianqi Wang Miaomiao Wang Wei Jiang Jing Jiang Xudong Li Yuehua Hu Dapeng Yin | 2022 | China CDC weekly2022,4,29: | 2 |
| 17 | Electrospun Scaff old of Collagen and Polycaprolactone Containing ZnO Quantum Dots for Skin Wound Regeneration显示文摘Nanofibers(NFs)have been widely used in tissue engineering such as wound healing.In this work,the antibacterial ZnO quantum dots(ZnO QDs)have been incorporated into the biocompatible poly(ε-caprolactone)/collagen(PCL/Col)fibrous scaffolds for wound healing.The as-fabricated PCL-Col/ZnO fibrous scaffolds exhibited good swelling,antibacterial activity,and biodegradation behaviors,which were beneficial for the applications as a wound dressing.Moreover,the PCL-Col/ZnO fibrous scaffolds showed excellent cytocompatibility for promoting cell proliferation.The resultant PCL-Col/ZnO fibrous scaffolds containing vascular endothelial growth factor(VEGF)also exhibited promoted wound-healing effect through promoting expression of transforming growth factor-β(TGF-β)and the vascular factor(CD31)in tissues in the early stages of wound healing.This new electrospun fibrous scaffolds with wound-healing promotion and antibacterial property should be convenient for treating wound healing. | Pengfei Li Liming Ruan Ruofan Wang Tianqi Liu Gao Song Xiaofei Gao Guohua Jiang Xiaoyan Liu | 2021 | Journal of Bionic Engineering2021,18,6: | 2 |
| 18 | Technological Exploration of RRAM Crossbar Array for Matrix-Vector Multiplication显示文摘矩阵向量增加是为许多计算地集中的算法的关键操作。抵抗切换的随机的存取存储器(RRAM ) 设备和 RRAM 闩穿的新兴的金属氧化物表明了模拟矩阵向量增加的一条有希望的硬件认识与超离频精力效率。在这篇论文,我们分析设备水平和电路水平的影响非理想的因素包括 RRAM 设备的非线性的当前电压的关系,设备制造的变化并且给操作,和 interconnect 抵抗以及另外的闩数组写参数。在那上,我们建议工艺的探索流动让设备参数配置克服非理想的因素的影响并且为各特定的申请在性能,精力,和可靠性之中完成一宗更好的交易。我们向量机器(SVM ) 和混合公民标准和技术(MNIST ) 模式识别数据集开创的支持的模拟结果证明那个 RRAM 闩数组基于 SVM 是柔韧的输入信号变化但是对通道差距偏差敏感。进一步的抵抗决定测试一台 6 位的 RRAM 设备对有能力的礼品在 90% 附近认识到识别精确性,显示 RRAM 闩数组的物理可行性基于 SVM。另外,建议工艺的探索流动能与以前的工作相比在 MNIST 数据集和 26.4% 精力积蓄上完成识别精确性的 10.98% 改进。试验性的结果也证明节省的超过 84.4% 力量能以很少精确性减小的成本被完成。 | Lixue Xia Peng Gu Boxun Li Tianqi Tang Xiling Yin Wenqin Huangfu Shimeng Yu Yu Cao Yu Wang Huazhong Yang | 2016 | Journal of Computer Science & Technology2016,31,1: | 2 |
| 19 | Cancer classification with data augmentation based on generative adversarial networks显示文摘Accurate diagnosis is a significant step in cancer treatment.Machine learning can support doctors in prognosis decision-making,and its performance is always weakened by the high dimension and small quantity of genetic data.Fortunately,deep learning can effectively process the high dimensional data with growing.However,the problem of inadequate data remains unsolved and has lowered the performance of deep learning.To end it,we propose a generative adversarial model that uses non target cancer data to help target generator training.We use the reconstruction loss to further stabilize model training and improve the quality of generated samples.We also present a cancer classification model to optimize classification performance.Experimental results prove that mean absolute error of cancer gene made by our model is 19.3%lower than DC-GAN,and the classification accuracy rate of our produced data is higher than the data created by GAN.As for the classification model,the classification accuracy of our model reaches 92.6%,which is 7.6%higher than the model without any generated data. | Kaimin WEI Tianqi LI Feiran HUANG Jinpeng CHEN Zefan HE | 2022 | Frontiers of Computer Science2022,16,2: | 2 |
| 20 | A time-driven transmission method for well logging networks显示文摘Long delays and poor real-time transmission are disadvantageous to well logging networks consisting of multiple subnets.In this paper,we proposed a time-driven transmission method(TDTM)to improve the efficiency and precision of logging networks.Using TDTM,we obtained well logging curves by fusing the depth acquired on the surface,and the data acquired in downhole instruments based on the synchronization timestamp.For the TDTM,the precision of time synchronization and the data fusion algorithm were two main factors influencing system errors.A piecewise fractal interpolation was proposed to fast fuse data in each interval of the logging curves.Intervals with similar characteristics in curves were extracted based on the change in the histogram of the interval.The TDTM is evaluated with a sonic curve,as an example.Experimental results showed that the fused data had little error,and the TDTM was effective and suitable for the logging networks. | Wu Ruiqing Chen Wei Chen Tianqi Li Qun | 2009 | Petroleum Science2009,6,3: | 2 |